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Ultra-pure hemodialysis concentrated solution manufacturing system and manufacturing technology

A technology of hemodialysis and manufacturing process, applied in dialysis systems, suction devices, etc., can solve problems such as contamination and non-ultra-pure raw and auxiliary materials

Inactive Publication Date: 2016-06-08
TIANJIN STANDARD BIOLOGICS CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because the composition of hemodialysis fluid is composed of a variety of raw and auxiliary materials, these raw and auxiliary materials are not ultra-pure, and they themselves contain a higher level of endotoxin and colony counts (compared to ultra-pure hemodialysis fluid); the production process There is also a risk of contamination

Method used

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  • Ultra-pure hemodialysis concentrated solution manufacturing system and manufacturing technology
  • Ultra-pure hemodialysis concentrated solution manufacturing system and manufacturing technology
  • Ultra-pure hemodialysis concentrated solution manufacturing system and manufacturing technology

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Embodiment

[0016] The following is attached with the manual figure 2 , 3 , the ultra-pure hemodialysis concentrate manufacturing system and process of the present invention are described in detail:

[0017] Such as image 3 As shown, the ultra-pure hemodialysis concentrate manufacturing system includes: a dynamic mixing and dissolving tank, an activated carbon adsorber, a modified resin adsorber, a precision filter, a liquid storage tank, and a set between the dynamic mixing and dissolving tank and the activated carbon adsorber The first pressure regulating pump, the second pressure regulating pump arranged between the modified resin adsorber and the precision filter; the dynamic mixing and dissolving tank has a heating function; the materials used are: sodium chloride, potassium chloride, chlorine Calcium chloride, magnesium chloride, glacial acetic acid, sodium bicarbonate; the manufacturing process includes: mixing and dissolving materials, constant volume, semi-finished product in...

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Abstract

The invention relates to a hemodialysis solution manufacturing system and a manufacturing technology, in particular to an ultra-pure hemodialysis concentrated solution manufacturing system and a manufacturing technology. The amount of endotoxin is smaller than or equal to 0.03 eu / ml, and the number of formed bacterial colonies is smaller than or equal to 0.1 cfu / ml. The ultra-pure hemodialysis concentrated solution manufacturing system comprises a dynamic mixing and dissolving tank (1), an activated-charcoal adsorber (2), a modified resin adsorber (3), a precise filter (4) and a liquid storage tank (5). The dynamic mixing and dissolving tank has a heating function. The system has the advantages that the activated charcoal adsorption and modified resin adsorption technology is adopted additionally, the technology is adopted for adsorbing endotoxin and the bacterial colonies in products, and after adsorption, endotoxin and the bacterial colonies are eliminated.

Description

Technical field: [0001] The invention relates to a hemodialysis solution manufacturing system and a manufacturing process, in particular to an ultrapure hemodialysis concentrate manufacturing system and a manufacturing process with endotoxin ≤ 0.03eu / ml and colony formation number ≤ 0.1cfu / ml. Background technique: [0002] In the prior art, the production process of hemodialysis concentrate is as follows: figure 1 shown. The endotoxin content and colony-forming number in the finished product of this production of hemodialysis concentrate have always been one of the troublesome technical problems. Generally, the highest level that can be achieved is: endotoxin ≤ 0.25eu / ml, colony-forming number ≤ 100cfu / ml. Because the composition of hemodialysis fluid is composed of a variety of raw and auxiliary materials, these raw and auxiliary materials are not ultra-pure, and they themselves contain a higher level of endotoxin and colony counts (compared to ultra-pure hemodialysis f...

Claims

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Application Information

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IPC IPC(8): A61M1/16
CPCA61M1/1656A61M1/166A61M1/1672
Inventor 马树君王以富马程锦侯洪凯王昊田文静张健
Owner TIANJIN STANDARD BIOLOGICS CO LTD
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