The invention discloses anti-allergy delicate-fragrance cream and a preparation method thereof. The anti-allergy delicate-fragrance cream comprises, by weight, 20-70 parts of bupleurum falcatum, 30-50 parts of Chinese gall, 20-40 parts of white oil, 40-60 parts of lanoline alcohol, 5-40 parts of Vaseline, 10-40 parts of lauric acid, 25-60 parts of lac, 15-45 parts of rheum officinale, 30-80 parts of vitamin, 40-60 parts of wheat germ oil, 30-70 parts of water-soluble essence, 50-70 parts of vegetable glue and 30-70 parts of water. The preparation method comprises the following steps of respectively putting bupleurum falcatum and Chinese gall into water, carrying out extraction, merging the supernatants, concentrating the extract, heating white oil, lanoline alcohol and Vaseline to a temperature of 50-60 DEG C, mixing the white oil, lanoline alcohol and Vaseline to obtain an oil phase, heating lauric acid and water to a temperature of 50-60 DEG C, mixing the lauric acid and water to obtain a water phase, slowly pouring the water phase into the oil phase with clockwise stirring of the oil phase, adding the rest of the ingredients and extract into the mixture, and carrying out continuous clockwise stirring to obtain the anti-allergy delicate-fragrance cream. The anti-allergy delicate-fragrance cream has effects of treating and resisting allergy and has anti-allergy effects improved by 16-20%.