158 results about "Spondylitis" patented technology

The invention relates to a Chinese traditional made medicine, in particular to an orally-taken pill preparation for treating cervical spondylosis, prolapse of lumbar intervertebral disc, hyperosteogeny, sciatica, spondylitis ankylosans and rheumatism and rheumatoid diseases. Canon of internal medicine considers that bone weakness and muscular flaccidity are so called that the three qi of wind, cold, dampness blends and combines to result in diseases; after all, either prolapse of lumbar intervertebral disc or annulus fibrosus bulge or spinal stenosis is the result of bone weakness caused by kidney deficiency, muscular flaccidity caused by liver deficiency and meridian blockage caused by wind cold phlegm blood stasis, the diseases are treated based on the principle of replenishing governor meridian and converging urogenital region, invigorating spinal cord and strengthening bones and muscles; and Wulong zhengzhui dan is developed based on the theory plus ancestral secret prescriptions. Wulong zhengzhui dan can treat cervical spondylosis, thoracic vertebra disease, lumbar vertebra disease, sciatica, spondylitis ankylosans and rheumatism and rheumatoid diseases for reinforcing kidney and strengthening resistance as well as supplementing vital substances and nourishing marrow, and can treat the diseases in both symptoms and causes without recurrence after healing.

The invention discloses application of an exosome of a mesenchymal stem cell source in preparation of a drug for treating ankylosing spondylitis. The exosome of the mesenchymal stem cell source has the inhibition effect on both chronic inflammations and pathological osteogenesis and has the advantages of being low in side effect and cost and more durable in effect.

The present invention discloses one kind of arthritis treating Chinese medicine composition and its preparation process. The Chinese medicine composition contains the effective components of frankincense, myrrh, safflower, curcuma, clematis root and other six kinds of Chinese medicinal materials, and may be prepared into granule, tablet, capsule or other pharmaceutical preparation form. It has the functions of promoting blood circulation to disperse blood clots, dredging meridian and relieving pain, and may be used in treating rheumatic arthritis, rheumatoid arthritis, bone arthrosis, gout and ankylosing spondylitis.

The invention provides a medicine for treating rheumatoid arthritis and ankylosing spondylitis and its preparation method, wherein the preparation is prepared form Chinese medicinal herbs incluing multibanded krait, black-tail snake, earthworm, buthus martensi kirsch, centipede, pangolin scales, American ginseng, dragon's blood resin, notoginseng, wood louse, batryticated silkworm, apiary, deer horn gum, root of herbaceous peony, arisaema tuber, corydalis tuber, licorice root, and borneol.

The invention discloses a medicine for treating rheumatoid arthritis, femur necrosis and ankylosing spondylitis wherein the medicine mainly comprises (by weight ratio) astragalus root, magnolia obavata, chicken's gizzard-skin, malt, amomum fruit, dried orange peel, medicated leaven, radix adenophorae, Chinese angelica root, Ligusticum wallichii, Poria cocos, bitter orange, atractylodes rhizome, white atractylodes rhizome, job's tears, large-leaf gentian root, Japanese yam, ledebouriella root, rhizoma corydalis, common fennel fruit, Chinese honeylocust spine, oyster shell, drynaria, buck grass, Bupleurum root, cimicifuga rhizome.

The invention relates to a Chinese medicine composition for treating ischemic necrosis of femoral head, which solves the problems that the western medicine only releases pain, the Chinese medicine has long treatment period and slow effect, and the operation treatment has large risk and high cost as well as easy recrudescence. The Chinese medicine composition is prepared by the following raw materials according to the weight proportion: 10-100g of angelica, 20-50g of corydalis tuber, 20-60g of heracleum hemsleyanum michaux, 20-40g of frankincense, 20-40g of myrrh, 10-50g of angelica dahurica, 20-50g of cinnamon, 30-100g of rhizoma drynariae, 20-60g of radix dipsaci from Sichuan of China, 20-50g of rhizoma cibotii, 40-100g of lopseed, 20-50g of dragon's blood and 10-50g of eupolyphage sece steleophaga. The Chinese medicine composition has short treatment period and rapid effect, can eliminate the ischemic necrosis of femoral head and the inflammatory pain of rachitis, can eliminate mechanical pain of cervical vertebra and lumbar intervertebral disc protrusion, can repair fiber ring scission, builds the health, improves the microcirculation without side and toxic effects, and promotes the sequestrum absorption of the ischemic necrosis of femoral head and the regeneration of the bone trabecula, thereby achieving the purpose of addressing both the symptoms and root causes.

The invention discloses a sinomenine vesicle and a preparation method thereof, a preparation containing the sinomenine vesicle and a preparation method of the preparation, which belong to the field of medicament preparations. The sinomenine vesicle is prepared from sinomenine, a nonionic surfactant and an additive. The sinomenine vesicle is preferably prepared into external gel. A sinomenine transdermal administration external preparation has a unique advantage to the medicament. Due to the application of a novel vesicle administration system, transdermal absorption of the medicament is improved, and a clinical curative effect is enhanced. The sinomenine vesicle can be used for treating rheumatism, rheumatoid arthritis, a glomerular disease, hyperosteogeny, spondylitis, arrhythmia, systemic lupus erythematosus, a heroin addict withdrawal symptom and the like.

The invention belongs to the field of Chinese medicaments, and relates to medicinal liquor for treating rheumatism, rheumatoid and pains of neck, shoulders, waist and legs. The medicinal liquor is prepared from prepared monkshood, prepared kusnezoff monkshood root, eucommia bark, safflower, cassia bark, medicinal cyathula root, whole worm, long-noded pit viper, divaricate saposhnikovia root, Chinese angelica, obscured homalomena rhizome, schizonepeta, clematis root, asarum, dipsacus root, pseudo-ginseng and white spirit. The Chinese medicaments and the white spirit with functions of promoting blood circulation are prepared into the medicinal liquor and are mutually supplemented and pressed; the medicinal liquor has the effects of eliminating the pathogenic factor without damaging healthy energy, supporting healthy energy without leaving pathogenic factor, promoting blood circulation to remove blood stasis, promoting blood circulation and regulating vital energy, promoting restoration of consciousness and activating collaterals, dispelling wind and dampness, warming meridians to dissipate cold, decreasing swelling and relieving pain, softening hardness to dissipate stagnation, reinforcing kidney to strengthen yang, alleviating pain and diminishing inflammation, clearing heat and detoxifying, cultivating blood losing muscles and bones of human joints, smoothing blood vessels and meridians and removing pathogenic factors of wind, cold, dampness and heat so as to eliminate various joint pains. The medicinal liquor has a unique curative effect on rheumatism, rheumatoid arthritis, pains of waist and legs, scapulohumeral periarthritis, numbness of limbs, sciatica, hyperostosis, protrusion of intervertebral disc, cervical spondylosis, ankylosing spondylitis, hyperplasia of mammary glands, various pains and chronic and stubborn diseases, crooked mouths and oblique eyes.

The invention involves a Chinese materia medica combination and its preparation technique, particularly involves a combination prescription and its preparation technique for treatment of dizziness hand numb and back and shoulder pain which is often seen in cervical syndrome; knee and loin aching and limp, lower extremity pain, heel pain often seen in lumbar spondylosis; limbs joint pain, intumesce, ankylosing spondylitis seen in rheumatism, rheumatoid arthritis disease. They are made into necessary dosage form according to clinical needs.

The invention discloses a method for testing susceptibility of ankylosing spondylitis. The method comprises the following steps that: a TAPI gene or a transcript of an individual is detected and compared with a normal TAPI gene or a normal transcript; and simultaneously, an LMP2 gene or the transcript of the individual is detected and compared with a normal LMP2 gene or the normal transcript, wherein the existence of difference shows that the possibility of the individual with ankylosing spondylitis is higher than that of a normal group. The invention also discloses a corresponding detection kit.

A Chinese medicine for treating syringomyelia, lateral sclerosis, chronic spondylitis, arachnoid adhesion, etc is prepared from 13 Chinese-medicinal materials including pilose antler, prepared rehmannia root, wolfberry fruit, ginseng, astragalus root, etc. Its advantages are high curative effect, no toxic by-effect and no recurrence.

A mechanical assembly for single point torque adjustment, an apparatus and a method of use of an improved belt for body support and for assisting body during musculoskeletal activities like heavy lifting, kneeling, bending and walking are provided. The belt employs the single point torque adjusting mechanical assembly with an adjustable hinge (104) along with resilient means (105, 105') which stores potential energy when the user alters from a neutral position and may help the body to return to the neutral position. The belt employs structure to share and direct load from head, neck, and back to waist and ground. The apparatus may prevent the user from acquiring spondylitis, kyphosis or osteoporosis. The apparatus may be used for users who are subjected to frequent muscular work like bending us and down while carrying heavy loads, sitting too long, walking and the like.

The invention discloses a medicine for treating rheumatoid arthritis and ankylosing spondylitis and its preparation method, which is mainly prepared from Clematis chinensis, arisaema tuber, cantharis, semen strychni, ledebouriella root, cassia twig and camphor by a predetermined weight ratio, the medicament fits for external use by patients.

The invention relates to a pharmaceutical composition for treating bone diseases, an injection thereof and preparation methods thereof. The pharmaceutical composition is composed of an extraction liquid of pig four limbs and a melon seed extraction liquid. Further, the pharmaceutical composition is added with mixed extraction liquids respectively prepared from commen bomhax flower, flos buddlejae and herba eupatorii. The prepared pharmaceutical composition has substantially improved treatment effect on rheumatoid arthritis, degenerative osteoarthritis, ankylosing spondylitis, sciatica, lumbar disc herniation and other bone diseases, is improved in treatment effect on gout and has no toxic and side effects. Additionally, the provided injection has extremely high stability and is substantial in effect.

The invention discloses an analgesic ointment with the function of relaxing tendons and activating collaterals, which is composed of the following ingredients: lovage, angelica, notopterygium, angelica, shenjincao, eucommia, clematis, achyranthes bidentata, rhizome rhizome, and bone supplement Fat, Aconitum, Speranthum, Nuxychia, Chuanduan, Safflower, Fangfeng, Wholeworm, Centipede, Frankincense, Myrrh, Dried Blood, Borneol, Camphor. The ointment of the present invention has strong penetrating power, quick drug effect, strong muscles and bones, expelling cold and dehumidification, promoting blood circulation, reducing swelling, relieving pain, dredging meridians, and can treat frozen shoulder, headache, swelling and numbness, lumbar disc disease caused by neck thrust disease. Sciatica caused by protrusion, numbness and pain in the waist and legs, lumbar muscle strain, ankylosing spondylitis, soft tissue contusion, unknown mass, mammary gland mass, tenosynovitis, rheumatic pain and other pain diseases have obvious curative effects.

The present invention includes compositions and methods for treating diseases or disorders associated with pathological calcification or pathological ossification. In certain embodiments, the diseases or disorders are selected from the group consisting of Generalized Arterial Calcification of Infancy (GACI), Idiopathic Infantile Arterial Calcification (IIAC), Ossification of the Posterior Longitudinal Ligament (OPLL), hypophosphatemic rickets, osteoarthritis, calcification of atherosclerotic plaques, PXE, hereditary and non-hereditary forms of osteoarthritis, ankylosing spondylitis, hardening of the arteries occurring with aging, calciphylaxis resulting from end stage renal disease and progeria.

The invention discloses a medicament for treating spondylitis, which is prepared mainly from deer horn gum, Cinnamomum cassia, Chinese ephedra, white mustard seed, buthus martensi karsch, centipede, root of red rooted saliva, bitter orange, morinda root, dipsacus root, east Asian tree fern rhizome, astragalus root and Chinese angelica root by a predetermined weight proportions. The medicament can be prepared into decoction, pills and capsules.

The invention provides a Chinese medicinal composition for treating rheumatic diseases, and a preparation method thereof. The Chinese medicinal composition is prepared from processed radix aconite, processed radix aconiti kusnezoffii, scorpions, honeycombs, menispermaceae roots, magnolia officinalis, calculus bovis factitious, liquorice and other raw medicinal materials. The preparation method comprises the following steps that: scorpions, honeycombs and menispermaceae roots are ground into coarse powder for standby; processed radix aconite, processed radix aconiti kusnezoffii, magnolia officinalis and liquorice are added with water 10 times the amount of the four materials, soaked for 2 hours, decocted for 2 hours, added with water 6 times the amount of the four materials and decocted again for 1 hour; decoction solutions are merged and filtered; filtrate is concentrated into thick paste of which the relative density is between 1.26 and 1.28 (65 DEG C); the thick paste is mixed well with the coarse powder; the mixture is dried in vacuum to be dry paste; the dry paste is ground into fine powder; the fine powder is ground with calculus bovis factitious; and the obtained product is sifted, mixed well and packed into capsules. The medicament has the efficacy in dispelling wind, promoting blood circulation, diminishing inflammation, easing pain and relaxing muscles, and is used for treating rheumatism, rheumatoid arthritis, ankylosing spondylitis, cervical spondylosis, lumbocrural pain, femoral head necrosis and the like, and has significant clinical effect.

The invention discloses a salt compound formed through the aceclofenac and the organic base and the assemblage and the use. The general formula of the salt compound is AxR mH2O; wherein, A is the aceclofenac (CAS RN: 89796-99-6) and x is 1, 2; R is nitrogen organic base and can be amine and basic amino acid. The amine is most suitable for being selected from the Meglumine and trometamol; the basic amino acid is most suitable for being selected from the Arginine, Lysine, Ornithine, Histidine and Citrulline. The spatial configurations of the amino acids include the DL type, D type, L type and optimized L type; m is 0, 1, 2, 3, 4, 5 and 6. The compound and the assemblage to which the invention relates can be applied to the diseases such as the inflammation and pain, sprain, pull, and other soft tissue injuries and fever, etc., caused by the rheumatoid arthritis, rheumatoid arthritis, osteoarthritis, spondylitis, etc. of the human beings or animals.

The invention discloses traditional Chinese medicine composition for treating bone fractures and a preparation method of the composition, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared to form a formula according to the principle of the monarch, the minister, the assistant and the guide; in the formula, stir-fried frankincense, stir-fried myrrh, stir-fried eucommia, common club herb, canton love-pea vine, Chinese angelica, sappan wood, Chinese gall, pangolin scales and garden balsam stem act on hearts, livers and spleens, have effects of promoting blood circulation to arrest pain, removing swelling and promoting granulation and serve asthe monarch; Chinese flowering quince, stir-fried nux vomica, dragon's blood, earthworms, safflower, centipedes, scorpions, lonicera vines, dahurian angelica roots and cassia bark have effects of dispersing blood, stimulating the menstrual flow, removing stasis and relieving pain and serve as the minister; forged native copper, fortune's drynaria rhizome, ground beetles, dipsacus roots, crabs and twotoothachyranthes roots serve as the assistant and have effects of benefiting livers, tonifying kidneys and promoting reunion of fractured bones; citron fruits, fennel fruits and sliced turmeric have effects of promoting qi circulation to relieve pain and guiding medicines to disease sites and serve as the guide. All the medicines are combined for use, so that the composition has effects of promoting blood circulation, removing stasis, relaxing channels, dredging collaterals, relieving swelling and pain and strengthening tendons and bones, is mainly used for treating various bone fractures and has significant effects on the bone fractures, spondylitis, femoral head necrosis and the like.

A Chinese medicine 'Anti-hyperosteogeny pill' for treating hypertrophic spondylitis, cervical spondylopathy, osteophyte, hyperplastic arthritis, etc is an improvement to existing relative medicine in the form of tablet. Its preparing process is also disclosed. Its advantages are high curative effect, high release speed and high biologic utilization rate.

The invention belongs to the field of medicine and pharmacology, and is Pharmaceuticals oral granule. The Aceclofenac granule is made by raw material drug aceclofenac, findings and disintegrant. The Aceclofenac granule is phenyl acetic acid non-steroidal anti-inflammatory agent. It has notable anti-inflammatory, analgesic and antipyretic effect. It applies to the treatment of various rheumatoid arthritis, atrophic arthritis, osteoarthritis and spondylitis. It is fit for pain and fever caused by various diseases, and the toxic and side effects is lower than other varieties. Aceclofenac has not granule in prior medicine market; it is innovative formula and benefit for absorbing drug to getting better curative effect and better taste. It is safe, reliable and new drug for treatment of acute, chronic pain and anti-inflammation.

The invention discloses a muscular and bone pain relieving medicinal liquor for treating ankylosing spondylitis. The muscular and bone pain relieving medicinal liquor mainly comprises raw materials including tripterygium wilfordii, safflowers, radix aconiti preparata, processed radix aconiti kusnezoffii, Himalayan teasel roots, (roasted) rhizoma atractylodis macrocephalae, obscured homalomena rhizome, rhizoma alismatis, ephedra, angelica sinensis, gentiana macrophylla, radix angelicae dahuricae, herba schizonepetae, zaocys dhumnade, radix cyathulae, licorice, cinnamon and glabrous greenbrier rhizome which are indicated by weight parts. The various raw materials which are Chinese herbal medicines are weighed according to the weight ratio of the muscular and bone pain relieving medicinal liquor for treating ankylosing spondylitis at first, are uniformly mixed, and are added into white spirit for soaking in a standing manner, and after filtering, filter liquor is separately packed to obtain finish medicinal liquor products. After being used for treating ankylosing spondylitis, the muscular and bone pain relieving medicinal liquor is obvious in curative effect, low in cost and free of toxic and side effect. Besides, the therapeutic effect for a patient using the medicinal liquor for treating ankylosing spondylitis is remarkable, and the effective rate is higher than 91%.

The invention discloses a preparation method of a compound three-snake powder composition. The compound three-snake powder has very good treatment efficacy on autoimmune diseases, can be used to fast and well treat rheumatoid arthritis, can be used to well treat gout, hypertension and ankylosing spondylitis, and can also used to realize beauty treatment, face nourishing and ageing delaying. The compound three-snake powder comprises, by weight, 10-30 parts of pit viper powder, 25-56 parts of zaocys dhumnade powder, 30-55 parts of dinodon rufozonatum snake powder, 10-15 parts of American ginseng, 5-8 parts of peach blossom, 6-9 parts of licorice root, 9-12 parts of Poria cocos, 5-7 parts of Spica Prunellae, 3-5 parts of unprepared Atractylodes lancea, and 10-15 parts of Herba Leonuri, and can be used to prepare various dosage forms, such as a tablet and a capsule.

The invention relates to application of ozonized oil in small surgical incisions or other wound such as mucosal ulcer, diabetic feet, cervical erosion, anal fissure, anus fistula, soft tissue injury,fall damage wound surface, recurrent wound, abscess, acne, arthritis, joint degeneration, cystitis, furunculosis, neurological disorder osteomyelitis, gangrene, ulcus cruris, synovitis, gout, sinusitis, spondylitis, scapulohumeral periarthritis, lumbocrural pain, periostitis and stomatitis. Through the modes of oral administration, intraperitoneal injection, clyster, gavage, intravenous injection,subcutaneous injection, intramuscular injection, external application, drop and suppository, the diseases can be effectively prevented and treated.

The invention discloses a method for preparing anti-hyperosteogeny tablets, which comprises the following steps of: crushing one half of suberect spatholobus stem and sieving, decocting the other half of suberect spatholobus stem, prepared rehmannia root, Chinese pyrola herb, burned fortune's drynaria rhizome, desertliving cistanche, epimedium herb and fried radish seed in water for two times, combining decocted filtrate, concentrating under reduced pressure to form thick paste, adding the crushed and sieved medicinal material into the concentrated thick paste, uniformly mixing, drying, crushing, adding auxiliary materials, uniformly mixing, pelleting, drying, tabletting and sugar-coating to obtain the anti-hyperosteogeny tablets. The anti-hyperosteogeny tablets prepared by the method have magic effect on hypertrophic spondylitis, cervical spondylosis, calcaneus spur, hypertrophic arthritis and kaschin beck disease, have higher dissolution rate and bioavailability than pills, have accurate dosage, stable quality, high yield and low cost, are convenient to take, carry, transport and the like, are suitable for mechanized production and easily meet the hygienic standard.

A Chinese medicine in the form of capsule for treating tonic spondylitis along with femur head necrosis is prepared from 12 Chinese-medicinal materials including Sichuan aconite root, astragalus, liquorice root, ground beetle, leech, etc through extracting and concentrating part of them, grinding others, mixing and capsulizing. Its advantages are high curative effect.

The invention relates to a medicine for treating ankylosing spondylitis, belonging to the technical field of orthopedics and traumatology treatment. The medicine is characterized by being prepared from the following active components in parts by weight: 2-4 parts of rhizoma cibotii, 1-3 parts of rhizoma curculiginis, 2-8 parts of dried body of ground beetle, 1-9 parts of rhynohophylla, 5-9 parts of astragalus membranaceus, 2-7 parts of cornu cervi degelatinatum, 2-6 parts of rhodiola rosea, 3-5 parts of asarum, 1-8 parts of myrrh, 3-7 parts of the root of bidentate achyranthes, 2-6 parts of radix clematidis, 1-8 parts of radix angelicae, 1-9 parts of pyrola, 2-8 parts of black semen sesame, 1-7 parts of poria cocos, 1-8 parts of divaricate saposhnikovia root, 2-8 parts of notopterygium root, 3-7 parts of ligusticum wallichii, 1-8 parts of the root of red-rooted salvia and 2-6 parts of lycopodium clavatum. According to the pathology principle of the ankylosing spondylitis and the reason for the ankylosing spondyliti, the medicine employs a pure traditional Chinese medicine formula, effective components are extracted to prepare the medicine into oral liquids, powder, tablets or capsules; when the medicine is orally taken and externally used, the ankylosing spondyliti can be effectively treated, and ideal effect is achieved.

The invention discloses application of BMP2 and Noggin in jointly preparing an ankylosing spondylitis diagnostic reagent kit.The invention further discloses application of BMP2 and Noggin in jointly preparing a reagent kit for predicting the severity of ankylosing spondylitis pathologic osteogenesis.The invention further discloses a BMP2 detection reagent kit and a Noggin detection reagent kit.By detecting the BMP2 level and the Noggin level at the same time, the specificity and sensitivity of diagnosis of ankylosing spondylitis can be improved, and the severity of ankylosing spondylitis pathologic osteogenesis can be predicted.By means of the BMP2 detection reagent kit and the Noggin detection reagent kit, the lower limit of the reagent kit detection allowable range is lowered, and the detection accuracy is improved.

A Chinese medicine for treating rheumatic and rheumatoid arthritis, hyperosteogeny, spondylitis, and ischemic femur head necrosis is prepared from 26 Chinese-medicinal materials including Sichuam aconite root, donkey-hide gelatin, phellodendron bark, Chuan-xiong rhizome, etc. Its preparing process is also disclosed.