The invention discloses a
traditional Chinese medicine composition for treating
rheumatoid arthritis and an extraction process thereof. The
traditional Chinese medicine composition is prepared from 10-30 g of thorny
elaeagnus root, 10-30 g of
bark of himalayan coralbean, 10-30 g of
kadsura longepedunculata root, 5-15 g of waxberry root, 5-15 g of
ardisia crenata, 5-15 g of rose mallow root, 5-15 g of glabrous sarcandra
herb and 3-9 g of
wikstroemia canescens root. The extraction process comprises the following steps: crushing the
traditional Chinese medicine components, sieving with a 12-mesh
sieve, uniformly mixing, adopting 60-80%
ethanol as an extraction
solvent, performing ultrasonic extraction under the conditions that the ultrasonic power is 500-700W, the frequency is 20-30KHz, the extraction temperature is 40-60 DEG C, the extraction time is 30-90min and the material-
liquid ratio is (8-12): 1 (mL / g), performing suction
filtration, and complementing the original volume to obtain an extracting solution. By optimizing the extraction process, the extraction efficiency and the quality stability are ensured; the extracting solution of the traditional Chinese
medicine composition can remarkably reduce the thickness of toes of mice, adjust
oxidative stress indexes, improve joint
pathological injuries and regulate and control JAK2 / STAT3 pathway related
protein expression, so that the effect of resisting
rheumatoid arthritis is achieved.