Pharmaceutical composition containing high-molecular complex for external use on skin and preparation method of pharmaceutical composition

By combining sodium humate with antibacterial and soothing compositions, a high molecular weight complex is formed, which solves the problems of limited antibacterial range and insufficient repair ability of existing topical skin preparations. It achieves effective antibacterial and rapid repair of the skin and is suitable for the improvement and health recovery of a variety of skin problems.

CN121197256APending Publication Date: 2025-12-26HUIZHOU ZHONGLI PHARMACEUTICAL TECHNOLOGY CO LTD
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Patent Information

Application Number
CN202511526846.3
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-10-24
Publication Date
2025-12-26

AI Technical Summary

Technical Problem

Existing topical skin preparations have a narrow antibacterial range and insufficient ability to repair damaged skin, leaving the skin still susceptible to infection after antibacterial treatment, which is not conducive to the healthy recovery of the skin.

Method used

Sodium humate is combined with an antibacterial and soothing composition to form a high molecular weight complex containing sodium humate, extracts of Eucommia ulmoides, Sophora flavescens, Cnidium monnieri, Pheretima aspergillum, and Kochia scoparia. The complex enhances the inhibitory effect on microorganisms, while ingredients such as tea oil and white petrolatum improve the skin barrier function.

Benefits of technology

It significantly enhances the inhibitory effect on microorganisms such as Candida albicans, Staphylococcus aureus, and Escherichia coli, promotes the rapid recovery of the skin to a healthy state, improves skin problems such as papular urticaria, eczema, tinea pedis, and perianal inflammation, and provides effective skin and mucous membrane repair and soothing.

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Abstract

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a pharmaceutical composition containing a high-molecular complex for external use on skin and a preparation method of the pharmaceutical composition, and the pharmaceutical composition comprises the following components in percentage by weight: 0.1-0.3% of sodium humate; 0.8 to 1.4% of a bacteriostatic composition; 0.8 to 1.4% of a soothing composition; 0.12 to 0.14 percent of chlorhexidine acetate; 6-20% of a humectant; 1-3% of an emulsifier; 0.1%-0.5% of a functional auxiliary material; the balance of pure water; the antibacterial composition comprises a glabrous sarcandra herb extract, a radix sophorae flavescentis extract and a fructus cnidii extract; the soothing composition comprises an earthworm extract and a fructus kochiae extract. The sodium humate is compounded with other components, so that the inhibition effect of the composition on microorganisms such as candida albicans, staphylococcus aureus and escherichia coli can be improved. Meanwhile, the sodium humate can effectively repair and relieve skin mucosa, so that the skin is quickly recovered to a healthy state.
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