The invention belongs to the field of traditional Chinese medicine and discloses a pelvic inflammatory disease treating medicine and a preparation method thereof. The pelvic inflammatory disease treating medicine comprises active medicinal materials including Sowthistle Tasselflower Herb, Herba Melastomatis Dodecandri, Juncellus serotinus, Polygonum posumbu, Radix Salviae Miltiorrhizae, Fortune Loosestrife Herb, Salix Alba, Fructus Cannabis, Herba Ixeris, Radix et Rhizoma Iridis Sanguineae, aerial roots of ficus microcarpa, Herba Strobilanthis Japonici, Rhizoma Ligustici Wallichii, Flos Rhododendri Mollis, Lignum Sappan and Cortex Cinnamomi. The selected medicinal materials are excellent in compatibility and perfect in complementation, has efficacies of blood circulation promoting, menstruation regulating, stasis removing, pain relieving, stasis dispersing, urination promoting, meridian warming and activating and the like, and jointly and straightly action in lesions. Therefore, the pelvic inflammatory disease treating medicine has the advantages of safety, convenience, freeness of toxic and side effects, high cure rate and quick action in treatment of symptoms including fallopian tube adhesion, irregular menstruation, pelvic effusion, pelvic bearing-down pain, uterus pressing pain, lower abdomen stabbing pain and the like caused by pelvic inflammatory and is cheap, easy to prepare and worthy of extensive clinical popularization and application.