68 results about "Skin sensitization" patented technology

The present invention relates to a bio-based and biodegradable superabsorbent polymer (SAP) comprising sodium alginate, modified cellulose, at least one activation agent, and at least one crosslinking agent. The SAP exhibits a high bio-based content of up to 93% and fulfills industrial composting standards such as EN 13432. The crosslinking reactions are performed under mild conditions, including ambient temperatures and neutral to alkaline pH, eliminating the need for high thermal energy. The resulting SAP granules demonstrate excellent liquid absorption performance, rapid swelling, high retention, and no observed toxicity or skin sensitization. The invention provides a sustainable alternative to petroleum-based SAPs for use in hygiene products, agriculture, and other disposable applications.

The invention discloses a collateral-dredging and pain-relieving gel plaster and a preparation method thereof. The collateral dredging and pain relieving ointment is prepared from the following raw materials in percentage by mass: camphor, borneol, menthol, absolute ethyl alcohol, collateral dredging and pain relieving volatile oil, a surfactant, collateral dredging and pain relieving extract, tartaric acid, purified water, partially neutralized sodium polyacrylate, a cross-linking agent, an adhesive, glycerol, EDTA-2Na (Ethylene Diamine Tetraacetic Acid) and a filling agent. The plaster disclosed by the invention is high in application comfort, breathable, free from aching feeling after being uncovered, free from residue on skin and not sticky when being in contact with sweat; the use of an organic solvent is basically avoided in the production process; the matrix contains components such as water and glycerol, has the effects of moistening the skin and promoting skin hydration, and is free of irritation and sensitization to the skin; repeated uncovering and pasting can be achieved, and the viscosity influence is small.

The utility model provides a novel medical application adhesive tape which comprises a base layer and further comprises an adhesive layer with one side adhered to the base layer and release paper separably adhered to the other side of the adhesive layer, a plurality of transverse tearing lines and longitudinal tearing lines are arranged on the release paper, and base layer tearing lines corresponding to the longitudinal tearing lines are arranged on the base layer. A plurality of air holes are formed in the base layer in an array mode, the base layer is coated with the adhesive layer in a latticed mode, the adhesive layer is arranged to avoid the air holes, the base layer is coated with the adhesive layer in a rectangular latticed mode, and the air holes are formed in the base layer in a rectangular array mode. The novel medical application adhesive tape provided by the utility model not only is safe and reliable to paste wounds at different parts, has a better using effect, but also has better air permeability, and relieves uncomfortable symptoms such as skin allergy, redness, itching and the like which are easily caused by long-time use.

The invention discloses a signal acquisition system of a self-adaptive film electrode patch for heart diseases, and relates to the technical field of medical instruments, the signal acquisition system comprises a flexible substrate, a nano electrode wire, an electrode patch and a circuit module; a bonding layer is arranged on the bottom surface of the flexible substrate, an anti-allergic medicine is distributed in the bonding layer, and the flexible substrate is used for being attached to the skin surface through the bonding layer; the plurality of nano electrode wires are distributed on the bonding layer of the flexible substrate, one ends of the plurality of nano electrode wires are respectively arranged at the detection points, the other ends of the plurality of electrode wires are connected with the circuit module, and the circuit module is used for outputting electric signals collected by the electrode paste; the electrode patch comprises a flexible conductive base layer and a contact layer, a printed circuit is arranged on one side of the flexible conductive base layer, the contact layer is attached to the printed circuit, the other side of the flexible conductive base layer is used for being bonded to a flexible substrate and located at a detection point, and the flexible conductive base layer is conducted with the nano electrode wire; the collection system is simple to operate, and solves the problems that an existing lead wire is easy to wind, the surgical field is affected, and skin allergy is caused by patch. The method has high use value and popularization value.

The invention discloses essence with uniformly distributed oil drops and a preparation process thereof, and relates to the field of cosmetics, the essence comprises a water phase component and an oil phase component, the water phase component comprises 50-99 parts by weight of purified water, 2-30 parts by weight of a moisturizing factor, 0.001-0.2 part by weight of a chelating agent, 0.001-5 parts by weight of a thickening agent, and 0.5-2 parts by weight of a preservative; the oil phase component comprises 1-15 parts by weight of a grease component; the essence is in a transparent state, oil drops are uniformly distributed, and no emulsifier is added, so that the problems of skin allergy, irritation and the like possibly caused by the emulsifier are avoided, the product is more suitable for being used by sensitive skin, the original characteristics of water and oil are reserved, and purer use experience is brought to consumers; the whole product is in a transparent state, oil drops are in a suspended state, and the product can be sprayed and smeared and has unique sense of science and technology and visual attraction.

This invention relates to the field of hydrogel electrode patch technology, and more particularly to a microstructured hydrogel patch and its preparation method, comprising a base layer, a conductive layer, and a hydrogel electrode layer stacked sequentially. The skin-contact surface of the hydrogel electrode layer is arrayed with micro-protrusions, each micro-protrusion having a micro-flared adsorption portion at its end, and an inward-curving portion at the end of the adsorption portion. A mesh-like breathing channel is provided between the micro-protrusions, and a breathable channel is axially opened on each micro-protrusion. A microporous one-way breathing valve communicating with the breathing and breathable channels is provided on the base layer. During preparation, the micro-protrusions and their end structures are formed using a mold, and the breathable channels are constructed. This invention enhances the adhesion between the patch and the skin through the micro-flared adsorption portion and the inward-curving portion, and combined with the breathable structure, improves breathability and wearing comfort, avoids skin allergies, and provides stable signal acquisition, making it suitable for long-term physiological signal monitoring.

The utility model discloses a navel patch, which comprises a navel patch body, an adhesive tape, a first adhesive tape and a second adhesive tape, and is characterized in that the navel patch body is provided with opposite inner and outer sides; the medicine core is arranged in the navel patch body, the medicine core is provided with a protruding part, the protruding part protrudes out of the inner side of the navel patch body, and the protruding part is attached to the navel of a user; and the protective cover is buckled on the navel patch body and covers the convex part of the medicine core. According to the utility model, the warm compress and the medicine core are integrally combined, so that the volatilization of the medicine effect is improved, and the product effect is improved; the protective cover prevents the medicine core from being squeezed in the transportation process and dirt caused in the packaging process, the medicine core is fixed by the breathable protective film, the protective film plays a role in fixing the medicine core and preventing the medicine core from moving, the problem that the medicine core is difficult to clean due to the fact that the medicine core falls into the navel hole is solved, and the breathable holes can effectively keep skin breathable and avoid skin allergy.

The invention discloses an application of a composition of isoliquiritigenin (glycoside), licochalcone and ethnic groups thereof in personal care products, and relates to the technical field of daily chemicals, and the composition is an anti-allergy soothing composition prepared based on a natural plant licorice extract isoliquiritigenin or a glycoside compound isoliquiritigenin thereof, licochalcone A and ethnic groups of licochalcone B, C, D, E and G. The traditional Chinese medicine composition has multiple functions of resisting allergy, relieving, resisting bacteria, diminishing inflammation, improving skin itch and stabbing pain and the like, does not contain hormones and antibiotics, has no toxic or side effect, is mild in effect and non-irritant to skin, can be used for treating skin allergy, red and swollen skin, itch and stabbing pain caused by various reasons, is applied to cosmetics and skin care products, such as gel, cream, masks and facial cleansers, and can be used for treating skin allergy, red and swollen skin, pruritus and stabbing pain caused by various reasons. The skin care product is mild to human bodies, safe and non-irritant, is suitable for sensitive skin, is suitable for people of all ages to use, has strong market competitiveness, and has relatively high economic and social benefits and the like.

The invention provides a silk fibroin composition for injection and a preparation method thereof, and belongs to the technical field of medical cosmetology. The silk fibroin composition is prepared from the following components in percentage by mass: 0.1 to 0.7 weight percent of hyaluronic acid or salt thereof, 0.1 to 10 weight percent of silk fibroin and the balance of phosphate buffer solution. The silk fibroin composition is used for water-light injection, can promote collagen production and inhibit collagen fibrosis, does not have adverse reactions such as skin allergy, hardening and the like, and has the effects of quickly improving the dry state of skin, fading fine wrinkles or wrinkles, replenishing water, preserving moisture and tightening the skin.

A depilatory emulsion containing paclitaxel is made from the following raw materials: 10% to 20% of oil, 8% to 12% of humectant, 4% to 6% of auxiliary emulsifier, 4% to 6% of emulsifier, 8% to 12% of paclitaxel solution, 0.5% to 1.0% of preservative, 0.01% to 0.05% of mineral, 0.05% to 0.10% of fragrance essential oil, and water for balance. This depilatory emulsion is designed to allow the paclitaxel and other active depilatory components to be absorbed by hair follicles while preventing absorption into dermis, thereby achieving advantages of an effective depilation, safety, absence of odor, reduced risk of skin allergy, and suitability for continuous use. A preparation method of this depilatory emulsion employs stepwise cooling and gradual emulsification to ensure that all components are fully dispersed and uniformly distributed, forming a stable emulsion system, which has advantages of simple steps and good emulsion stability.

The invention discloses indigowoad root indigo antibacterial solid soap and a preparation method thereof. The indigowoad root indigo antibacterial solid soap is prepared from the following components in parts by mass: 5-30 parts of indigowoad root powder, 1000-1100 parts of soap base and 36-40 parts of coconut oil. The invention relates to the technical field of daily chemicals. According to the indigo indigo antibacterial solid soap and the preparation method thereof, high-purity indigo indigo powder is specially extracted, and a low-temperature cold soap making method is adopted, so that decomposition of indigo indigo and indirubin under high temperature and strong alkali is greatly avoided, and high efficiency of antibacterial and anti-inflammatory biological activity is ensured; impurities in crude indigo naturalis are removed, the risk of skin allergy and friction is reduced, the compounded soap base also makes the soap foam fine and smooth, and the skin is moist and not tight after the soap is used.

The application provides a kind of image positioning sticker marking method based on iodine-gallium complex chelate, through chelation reaction to prepare excellent stability iodine-gallium complex developer, non-woven fabric substrate is modified by chitosan coating, combined with screen printing process to prepare high-precision positioning sticker, and establish standardized clinical marking process. The method uses iodine-gallium double element synergistic development mechanism, so that the CT value of the marking area is 350-400HU, the contrast of the surrounding tissue is improved by 40%, the development clarity retention rate is more than 92% after 48 hours of sticking, the positioning error is stable within 0.3mm, solves the pain points of traditional marking easy diffusion and poor adhesion. The application has excellent biocompatibility, the skin allergy rate is only 0.8%, the single patient positioning operation time is shortened to 5-10 minutes, the production cost is reduced by 40%, can be widely used in precise medical positioning scenes such as tumor radiotherapy and interventional surgery, has significant clinical popularization value.

This invention belongs to the field of essential oil preparation technology, specifically relating to a method for preparing hypoallergenic agarwood essential oil and its application. The method involves desensitizing the raw agarwood essential oil obtained by supercritical carbon dioxide extraction. The desensitization process involves heating at low temperature followed by dissolution with water to remove the sensitizing components. The agarwood essential oil prepared by this method can reduce skin sensitization and irritation while retaining the main active ingredients of the agarwood essential oil.

The present application relates to the technical field of computational theoretical chemistry, and particularly relates to a preparation and optimization method of a long-acting moisture-permeable anti-allergic electrocardio electrode, which comprises the following steps: setting electrode-skin interface stability target parameters; calculating the binding energy strength of each candidate polymer material and the skin stratum corneum, and screening the candidate polymer material meeting the allergic reaction probability threshold; constructing a microporous structure model according to the chemical molecular structure of the candidate polymer material, adjusting the micropore gradient distribution parameters until the simulated sweat diffusion rate reaches the sweat diffusion rate threshold; performing dynamic impedance simulation, and when the detection does not reach the impedance decay rate threshold, re-triggering the adjustment of the micropore gradient distribution parameters; and generating and outputting the physical structure parameter set of the electrocardio electrode based on the micropore gradient distribution parameters and the microporous structure model. Through the present application, the problems of insufficient moisture permeability, electrical signal attenuation and skin allergy risk caused by the conflict between sweat diffusion and interface impedance during the material selection and preparation of the existing electrocardio electrode are effectively solved.

The utility model relates to an infusion film for a remaining needle, and aims to solve the problems of the traditional film in the aspects of stability, air permeability, observation convenience, material waste and the like. The sticking film consists of a main sticking film and an extended sticking strip which are fixedly connected into a whole. An observation window groove is formed in the main pasting film, so that medical staff can directly observe the puncture part of a patient under the condition that the pasting film is not removed. The edge of the observation window groove is subjected to smooth treatment so as to reduce irritation to the skin of a patient. Both the main pasting film and the extension pasting strip are made of medical-grade non-woven fabrics or polyurethane materials with low sensitivity and good air permeability, so that the comfort level of a patient is improved, and the risk of skin allergy is reduced. Through the design of the pasting film, the stability is enhanced, the air permeability is improved, the effects of observation convenience and material saving are achieved, and safer, more comfortable and more efficient nursing service is provided for a patient.

The utility model relates to the technical field of medicine patches, and discloses an acupuncture point patch convenient to paste and tear, which comprises a positioning frame, a detachable frame is sleeved on the outer surface of the positioning frame, a handrail is inserted in the detachable frame, a tear film is arranged in the detachable frame, and the positioning frame, the detachable frame, the handrail and the tear film are arranged in the detachable frame. The acupuncture point patch is reasonable in structure, medicine in the fixing ring is heated by the heating layer through the breathable layer in the using process, the medicine is volatilized, the breathable layer enables the medicine to be volatilized and breathable, skin allergy caused by stuffiness at the application position due to the fact that the acupuncture point patch is not breathable is reduced, the connecting buckle is in butt joint with the snap fastener, the breathable layer is fixed, and the acupuncture point patch is convenient to use. The problem of displacement of the breathable layer in the using process is solved, the hollowed-out breathable plate is in butt joint and pasted through the pasting layer, the cleaning cloth is folded to be folded into the hollowed-out breathable plate, the cleaning cloth is folded to wipe the pasting position of the cleaning cloth, and the problem that the skin is allergic due to the fact that wiping is not in place is solved.

This information processing device comprises a processor, wherein the processor uses a plurality of determination models pertaining to different events among a plurality of events including an important event in an expression pathway of skin sensitization of a chemical substance and including an expression itself of skin sensitization, outputs a determination result of presence / absence of skin sensitization of the chemical substance from each of the determination models, and performs final determination of presence / absence of skin sensitization of the chemical substance on the basis of a plurality of determination results output from each of the determination models.

The invention discloses a skincare stem cell exosome separation and extraction method, and relates to the technical field of biological medicine, the skincare stem cell exosome separation and extraction method comprises the following steps: S1, culture of mixed stem cells: unfreezing urine-derived stem cells and pilose antler stem cells, resuspending in an improved DMEM culture medium, and carrying out mixed culture to prepare a mixed culture solution; epidermal growth factors, cholera toxin, penicillin, streptomycin, transferrin, IL-2 and IL-15 are added into the improved DMEM culture medium; s2, pretreatment of the mixed culture solution: performing centrifugal treatment on the mixed culture solution, and separating to obtain a precipitate and a supernatant, the precipitate being mixed stem cells. The urine-derived stem cells and the pilose antler stem cells are subjected to mixed culture and matched with the improved culture medium containing IL-2, IL-15 and other components, so that the yield and biological activity of the exosome are remarkably improved, high purity and low impurity protein residue of the exosome are achieved by means of a complete purification process of multi-step centrifugation, ultrafiltration concentration and filter membrane filtration, and the yield of the exosome is improved. The skin allergy stimulation risk is effectively reduced.

This application discloses a plant extract composition, its preparation method, and its application. The plant extract composition is prepared by mixing trumpet creeper alcohol extract, thistle glycerol extract, and cardamom alcohol extract in a mass ratio of 100:(28~305):(28~305). The combination of these three extracts in the composition exhibits a synergistic effect, effectively protecting the skin from UV damage while simultaneously soothing and repairing it, achieving both core benefits and overcoming the limitations of traditional single-herb extraction methods that cannot fundamentally address skin allergies and fragility. Furthermore, the use of alcohol and glycerol extraction methods, compared to the irritating organic solvents used in traditional processes, is more suitable for people with sensitive skin, broadening the product's applicability.

A method of predictively assessing skin sensitization of a personal care product formulation includes: calculating an upper confidence limit at a desired confidence level from multiple physical tests for skin sensitization of each of the ingredients in the personal care product formulation to define calculated skin sensitization values for the respective ingredients; applying at least one safety factor to at least one of the calculated skin sensitization values for the ingredients to define adjusted skin sensitization values for the respective ingredients; summing the adjusted skin sensitization values of the ingredients to define a total sensitization of the personal care product formulation; and comparing the total sensitization to a target product sensitization for the personal care product formulation. Such personal care product formulations do not require further testing and are capable of application to skin by users. Predictive systems and methods of preparing a personal care products are also disclosed.

The invention discloses an elastic antibacterial fabric as well as a preparation process and application thereof, and relates to the technical field of antibacterial fabrics, in order to realize long-acting antibacterial and hydrophilic effects of spandex fibers, the spandex fibers are subjected to intrinsic antibacterial treatment, a synthesis scheme of the spandex fibers is improved, guanidyl groups are introduced into the fabric fibers, and the antibacterial effect of the fabric is improved. The sulfonic acid group introduced in the process can significantly enhance the hydrophilicity of the spandex fiber, so that the spandex fiber has good moisture spreading ability, the defect of sweat accumulation caused by poor hydrophilicity due to sweating after exercise is avoided, and the antibacterial property of the synthetic fiber is improved; and the strong antibacterial property brought by guanidyl also can inhibit the reproduction of bacteria, so that the defects of bromhidrosis and even skin allergy are avoided.

This invention discloses a method for preparing tree tomato leaf extract, its products, and applications, belonging to the field of natural product extraction and application. The method involves taking tree tomato leaf powder, using a 60% ethanol aqueous solution as the extraction solvent, extracting at a material-to-liquid ratio of 1:30 g / mL and a temperature of 60°C for 45 min, repeating the extraction twice, combining the two filtrates, concentrating, and drying to obtain the tree tomato leaf extract. This extract is highly enriched with polyphenols, flavonoids, and other active ingredients, exhibiting multiple effects such as antioxidant, anti-inflammatory, tyrosinase inhibition, and promotion of hyaluronic acid synthesis. It has also been confirmed that it has no significant cytotoxicity, phototoxicity, or skin sensitization. Cosmetic compositions containing this extract can effectively improve skin hydration, barrier function, redness, and dullness, and are suitable for preparing multifunctional pharmaceuticals or cosmetics with anti-inflammatory, whitening, moisturizing, and anti-aging properties, providing strong support for the high-value utilization and development of tree tomato leaf resources.

The application discloses a soothing and repairing composition and application, and relates to the cosmetic technical field.The soothing and repairing composition comprises kava root extract, mussel extract, catnip extract and verbena flower extract.The four components have a synergistic effect, can repair the skin barrier, heal the skin structure, reduce the inflammatory reaction, and have a good moisturizing effect.The soothing and repairing composition can instantly soothe the skin allergic reaction and repair the skin barrier, restores the skin to a healthy state, is mild and non-irritating, and has a relatively wide application prospect.

The invention provides low-toxicity and low-sensitization fluororubber watchband glue as well as a preparation method and application thereof, and belongs to the technical field of rubber materials. According to the technical scheme of the invention, the raw fluororubber is polymerized by adopting the surfactant containing no fluorine element, and meanwhile, the reinforcing filler system is optimized, so that the skin sensitization and stimulation risks are remarkably reduced. The fluororubber watchband adhesive prepared by the preparation method disclosed by the invention shows excellent biological safety in a cytotoxicity test. The invention provides a novel environment-friendly material solution with safety and reliability for the field of wearable equipment, particularly watchband products in long-term contact with human skin, and has definite market application prospect and popularization value.

The application discloses a kind of semi-fluorocarbon for removing emulsified silicone oil filling and its preparation method and application, comprising, olefin and perfluoroalkyl iodine are dissolved in acetonitrile, initiator is added and reacted under light source, to obtain fluorine-containing iodoalkane;Fluorine-containing iodoalkane is dissolved in isopropyl alcohol, and after adding reducing agent and heating reaction, it is washed to obtain semi-fluorocarbon with the structure of CF3 (CF2) 3 (CH2) 4CH3, named semi-fluorinated nonafluorononane;Wherein, the molar ratio of the olefin and perfluoroalkyl iodine is 1:1-1.4, and the initiator is cuprous chloride.The application controls the proportion of raw materials, carries out reaction under the condition of suitable initiator, simultaneously preferably zinc powder is used as reducing agent, effectively improves product purity and product yield, and operation process is simple, safe, and CF3 (CF2) 3 (CH2) 4CH3 prepared has not only good stability, but also good biocompatibility, no cytotoxicity, no skin sensitization, no acute eye irritation, can dissolve or wrap emulsified silicone oil droplets, and play a great role in the removal of emulsified silicone oil.

The present application belongs to the technical field of cosmetics, and particularly relates to a bird's nest composition capable of reducing the sensitization of cosmetic ingredients, which is composed of the following components in parts by weight: 30-60 parts of bird's nest acid, 10-30 parts of bird's nest peptide, 10-20 parts of bird's nest extract, and 1-30 parts of hydrolyzed bird's nest. The present application is derived from natural bird's nest and has good moisturizing and anti-allergic effects, and can effectively reduce the allergy caused by irritating substances in cosmetics, and solve the problem of skin sensitization caused by irritating ingredients in cosmetics.

The invention relates to the technical field of multi-layer fabrics, in particular to a preparation method of a natural multi-layer anti-allergic garment fabric and a garment. Comprising the following steps: preparing propylene glycol alginate-sitosterol microcapsules, preparing an isosorbide-sodium alginate cross-linked body, and preparing the natural multi-layer anti-allergic garment fabric. According to the invention, the propylene glycol alginate and the beta-sitosterol are prepared into microcapsules, the microcapsules are used on the anti-allergy coating of the fabric, the microcapsules as phytosterol and beta-sitosterol can inhibit cells from releasing histamine so as to reduce skin anaphylaxis, and the polysaccharide structure of the propylene glycol alginate can also form a certain physical barrier, so that the anti-allergy effect of the fabric is improved. The anti-allergy garment material has the advantages that the anti-allergy garment material can be applied to the garment material, direct contact between external irritants or other components and skin can be reduced, allergy risks can be reduced, amphiphilic networks can be constructed by the beta-sitosterol and the propylene glycol alginate, accordingly, microencapsulation embedding can be realized, the sitosterol can be prevented from being layered or crystallized and separated out due to density difference, and anti-allergy effects of the garment material can be prolonged.

This invention discloses a method for preparing anthocyanin extract from tree tomato, along with its products and applications, belonging to the field of natural plant extraction and application. The method uses tree tomato peel as raw material, employing an acidic ethanol aqueous solution containing 0.5% (w / v) trifluoroacetic acid as the extraction solvent, at a material-to-liquid ratio of 1:30 (g / mL), at a temperature of 50℃, and for 60 minutes to obtain a high-content anthocyanin extract. This tree tomato anthocyanin extract possesses excellent anti-inflammatory, antioxidant, anti-glycation, elastase-inhibiting, and whitening activities, and exhibits low cytotoxicity, no phototoxicity, and no skin sensitization. The efficient and stable anthocyanin extraction process provided by this invention has high extraction efficiency and good enrichment effect of active ingredients, meeting the requirements for subsequent industrial production. The obtained extract has whitening, anti-aging, and anti-inflammatory effects, providing a high-quality raw material and formulation solution for developing multifunctional and highly safe natural plant-based skincare products.

The utility model discloses a novel hair dyeing protection tool, belongs to the technical field of hair dyeing protection, and aims to solve the technical problem that the face and the neck of a hair dyeing person are easily stained with hair dye in the hair dyeing process in the prior art. The novel hair dyeing protection tool comprises an inner sheath, the inner sheath is of an annular structure and has the flexible characteristic, the inner sheath is provided with a fracture, the two ends of the fracture of the inner sheath are provided with a male connecting lug and a female connecting lug respectively, and the male connecting lug and the female connecting lug are connected so that the inner sheath can be hooped on the head of the human body; and the outer sheath also has a flexible characteristic, the outer sheath is arranged around the outer side of the inner sheath, the bottoms of the outer sheath and the inner sheath are connected into a whole, and the two ends of the outer sheath are respectively connected with the two ends of the fracture of the inner sheath in a closed manner. The novel hair dyeing protection tool has a good hair dyeing protection effect, and solves the problem that the hair dye is easy to drop on the face, neck and other skins of a hair dyeing person to possibly cause skin anaphylaxis.

The invention provides a pure natural skin care composition with acne removing and mark fading functions and a preparation method and application thereof, and relates to the technical field of daily necessities. The pure natural skin care composition is prepared from the following components in parts by weight: 20 to 30 parts of alfalfa extract, 10 to 20 parts of tilia latifolia flower extract, 2 to 4 parts of pachysandra repens fruit extract, 2 to 4 parts of flos eriocauli flower / stem extract, 2 to 4 parts of porphyra yezoensis polysaccharide and 2 to 4 parts of polianthes tuberosa polysaccharide. The composition disclosed by the invention is safe, mild and non-irritating, has better anti-inflammatory and acne-removing effects, is not easy to relapse, solves the problem of skin inflammation caused by acnes, lightens acne marks, does not cause skin allergy, and reduces adverse reactions in a use process.