89 results about "Antiallergic agent" patented technology

A drug for topically administration which is effective as an antiallergic agent. The drug for topically administration contains as an active ingredient an adenine compound represented by the general formula (1):[wherein ring A represents a 6 to 10 membered, mono or bicyclic, aromatic hydrocarbon or a 5 to 10 membered, mono or bicyclic, aromatic heterocycle containing one to three heteroatoms selected among 0 to 2 nitrogen atoms, 0 or 1 oxygen atom, and 0 or 1 sulfur atom; n is an integer of 0 to 2; m is an integer of 0 to 2; R represents halogeno, (un)substituted alkyl, etc.; X1 represents oxygen, sulfur, NR1 (R1 represents hydrogen or alkyl), or a single bond; Y1 represents a single bond, alkylene, etc.; Y2 represents a single bond, alkylene, etc.; Z represents alkylene; and at least one of Q1 and Q2 represents —COOR10 (wherein R10 represents (un)substituted alkyl, etc.), etc.] or a pharmaceutically acceptable salt of the compound.

The present invention provides an 8-oxoadenine compound having immunemodulating activities such as an interferon inducing activity and useful as an antiviral agent and antiallergic agent, which is represented by the following formula (1):[wherein the ring A represents a 6-10 membered aromatic carbocyclic ring and the like, R represents a halogen atom, an alkyl group and the like, n represents an integer of 0-2, Z1 represents alkylene, X2 represents oxygen atom, sulfur atom, SO2, NR5, CO, CONR5, NR5CO and the like, Y1, Y2 and Y3 represent independently a single bond or an alkylene group, X1 represents oxygen atom, sulfur atom, NR4 (R4 is hydrogen atom or an alkyl group) or a single bond, R2 represents a substituted or unsubstituted alkyl group, R1 represents hydrogen atom, hydroxy group, an alkoxy group, an alkoxycarbonyl group or a haloalkyl group]or its pharmaceutically acceptable salt.

A medicament for the preventive and / or therapeutic treatment of allergic diseases and / or endometriosis and / or hysteromyoma which comprises as an active ingredient a substance selected from the group consisting of a compound represented by the following general formula (I) and a pharmacologically acceptable salt thereof, and a hydrate thereof and a solvate thereof:wherein X represents a connecting group whose number of atoms in the main chain is 2 to 5 (said connecting group may be substituted), A represents hydrogen atom or acetyl group, E represents an aryl group which may be substituted or a hetero aryl group which may be substituted, ring Z represents an arene which may have one or more substitutents in addition to the group represented by formula —O-A wherein A has the same meaning as that defined above and the group represented by formula —X-E wherein each of X and E has the same meaning as that defined above, or a heteroarene which may have one or more substitutents in addition to the group represented by formula —O-A wherein A has the same meaning as that defined above and the group represented by formula —X-E wherein each of X and E has the same meaning as that defined above.

The invention relates to a whitening and moisturizing toner which is especially used for human face skin. The whitening and moisturizing toner is prepared by the following steps: heating 3-5 parts of 1,3-butylene glycol, 4-6 parts of sodium pyrrolidone carboxylate, 0.2-0.4 part of dipotassium glycyrrhizinate, 2-4 parts of NMF-50, 4-6 parts of antiallergic agent (CD-2901), 100-110 parts of pure water, 4-6 parts of hyaluronic acid (1%), 1.5-2.5 parts of arbutin, 4-6 parts of nonane diacid derivative and the like, keeping the temperature, and stirring. Compared with the prior art, the invention has the following advantages: 1. the whitening and moisturizing toner does not have the smell or color of Chinese medicinal herbs, and thus, is welcomed by users; 2. since the antiallergic agent (CD-2901) is added into the product, the whitening and moisturizing toner can prevent skin allergy, so the users can use the whitening and moisturizing toner safely; and 3. since the whitening agent, moisturizing agent and humectant are added into the whitening and moisturizing toner, the whitening and moisturizing toner not only can soften the skin, but also can perform the function of nourishing the skin.

Tricyclic triazolobenzazepine derivatives in the form or a prodrug are provided. The compounds according to the present invention are those represented by formula (I) and pharmacologically acceptable salts and solvates thereon. The compounds are useful as antiallergic agents and exhibit excellent bioavailability. wherein R1 represents hydrogen, OH, alkyl or phenyl alkyl, R2, R3, R4, and R5 represent hydrogen, halogen, optionally protected hydroxyl, formyl, optionally substituted alkyl, alkenyl, alkoxy or the like, and Q represents a group selected from the following groups (i) to (iv), halogen, or alkoxy:

It is intended to provide an anti-allergic agent, which efficaciously relieves symptoms accompanying an allergic disease without causing any serious side effect. This object is achieved by providing an anti-allergic agent which contains, as an effective ingredient, proteins collected from royal jelly or purified royal jelly, or royal jelly or purified royal jelly containing the proteins.

A drug effective for prevention and therapy of endometriosis is disclosed. The drug for prevention and / or therapy of endometriosis according to the present invention comprises an antiallergic agent as an effective ingredient.

The present invention provides an antiallergic agent containing, as an active ingredient, lactic acid bacteria selected from the group consisting of lactic acid bacteria of the species Lactobacillus acidophilus, Lactobacillus fermentum, and combinations thereof. The antiallergic agent is capable of improving allergic diathesis by reducing the IgE level, which is contributive to development of Type I allergy, and is easy to take and highly safe. The present invention also provides use of the antiallergic agent for reducing allergy, and a method for reducing allergy using the antiallergic agent.

It is intended to provide an anti-allergic agent, which efficaciously relieves symptoms accompanying an allergic disease without causing any serious side effect. This object is achieved by providing an anti-allergic agent which contains, as an effective ingredient, proteins collected from royal jelly or purified royal jelly, or royal jelly or purified royal jelly containing the proteins.

An object of the present invention is to provide an antiallergic composition useful for preventing and treating allergies, its preparation method, and its use as food, beverages, and the like. The solution includes an anti-allergic composition, which contains lactic acid bacteria with the following effects as an active ingredient: lymphocytes derived from the spleen of mice sensitized with ovalbumin are suspended in a culture medium containing ovalbumin, and added to When the lactic acid bacteria to be tested are cultured, the production of interleukin 12 is equivalent to that when Lactobacillus casei-like KW3110 strain is used as the lactic acid bacteria to be tested, or more than 60% of that when Lactobacillus casei-like KW3110 strain is used as the lactic acid bacteria to be tested, and the interleukin 12 The production amount of 4 was less than 50% of the control without adding lactic acid bacteria. The present invention includes a method for obtaining lactic acid bacteria with high anti-allergic activity as an active ingredient of the anti-allergic composition of the present invention, and the application of the anti-allergic composition of the present invention in food, beverages, etc., and further includes a method for preparing the lactic acid bacteria with high anti-allergic activity. , for use as an orally administered antiallergic agent.

The invention belonging to the field of cosmetics, and particularly relates to a Sargassum horneri alga powder mask and a preparation method thereof. The preparation method comprises the following steps: removing impurities from Sargassum horneri, washing, drying until the algae become embrittled, and pulverizing the dried Sargassum horneri to granules; regrinding the Sargassum horneri granules into powder, and screening to obtain Sargassum horneri powder; weighing raw materials according to the formula; adding deionized water into the weighed Sargassum horneri powder, and stirring to swell; and dissolving a moisturizer, an antioxidant, a metallic ion chelator, a preservative, a whitener, a deodorizer, a sebum inhibitor, a cutin dissolving agent, a bacteriostatic agent, an antiallergic agent and a nutrient additive in deionized water, adding the Sargassum horneri clay, continuing stirring while adding a tackifying agent and deionized water, and stirring uniformly. The mask has the advantages of favorable moisturizing property, low cost and low price, obviously improves the skin color, moisturizes the skin, prevents the skin from aging, reduces the wrinkles and is convenient to use.

The invention relates to the field of daily chemicals, in particular to a novel skin bacteriostat. The skin bacteriostat is characterized by being prepared from, by weight, 0.5-8% of humectants, 0.5-5% of emollient and 0.1-2% of an antiallergic agent; a bacteriostatic agent at least comprises, by weight, 0.1-1.5% of lysozyme, 0-0.2% of odorant and 0-0.4% of solubilizer; water is added until the total weight percentage is 100%. According to the principle of integration of prevention and treatment, the bacteriostatic agent which is natural, safe and free of irritation is adopted and matched with high-purity cosmetic materials, resistance of skin to external virus and bacteria invasion and irritation is improved while epidermis germs are killed, a natural protection barrier is formed for the skin, and the skin is well repaired, moisturized and cared to keep comfortable and healthy durably.