The invention belongs to the technical field of biological
medicine, and discloses disposable
eye lotion for double-effect repair of
cornea and a preparation method of the disposable
eye lotion. The eye moistening liquid comprises 0.1-0.3% by
mass volume of
sodium hyaluronate with the weight-average molecular weight of 50,000-200,000 Da and 0.05-0.2% by
mass volume of
chitosan with the number-average molecular weight of 3,000-10,000 Da and the deacetylation degree of more than or equal to 85%, the
mass ratio of the
sodium hyaluronate to the
chitosan is 2: 1-6: 1, a
phosphate buffer
system and
sodium chloride are used for adjusting the pH value to 6.5-7.8, and the
osmotic pressure is 260-340 mOsm / KgH2O. The functional limitation that traditional eye moistening liquid is only limited to symptom relieving is broken through, a prevention and repair integrated
ocular surface nursing solution is constructed, the product has the double-effect functions of instant
lubrication and promotion of
corneal epithelial cell migration and proliferation and barrier reconstruction under the
preservative-free condition, and the product is stable in physicochemical property, high in safety and suitable for popularization and application. A novel intervention means with safety, effectiveness and convenience is provided for
contact lens related
ocular surface damage.