1075 results about "Skin wound" patented technology

An oxygenation and temperature thermal therapy and oxygenation treatment pad with a plurality of air chambers is disclosed for treatment of skin wound tissues. The air chambers are filled and released by a valve assembly that may be separate from or integrated within the blanket. The thermal therapy and oxygenation treatment pad includes a fluid bladder for delivering hot and / or cold therapy to a patient in conjunction with oxygenation. The temperature therapy blanket may also include an air bladder for providing compression. Oxygenation is provided subsequent to initial heating in order to promote oxygen absorption by the wound tissues prior to the cooling thereof which facilitates pulling oxygen into the wound tissues. This Abstract is provided to comply with rules requiring an Abstract that allows a searcher or other reader to quickly ascertain subject matter of the technical disclosure. This Abstract is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. 37 CFR 1.72(b).

The invention discloses a skin wound locking device for facilitation of wound natural healing, which comprises two strip shape support band and base band arranged along the two sides of the skin wound, wherein the base band is arranged on the upper surface of the bar-shaped support band, the base band is provided with one or multiple pairs of locking device for connecting the base band. The skin wound locking device can facilitate wound permeability, drainage and medicine changing, and also facilitate the survey for wound healing condition, thus can be widely applied to the wound closure of surgical operation.

A portable, self-contained device is described for the topical application of oxygen and the removal of wound exudates to promote the healing of skin wounds. The device includes a wound dressing that incorporates at least one electrochemical cell for generating oxygen. The device can regulate the supply of oxygen to the wound at various concentrations, pressures and dosages and is used to produce a high concentration of oxygen at the wound site. By reversing the polarity of the power source a reduced pressure can be created in a reservoir attached to our device. The reduced pressure in the reservoir draws naturally flowing exudates away from the wound. Alternately, two reverse polarity cells are used to alternately supply oxygen and draw away exudates.

A method and device for inducing or promoting growth and proliferation of skin cells or tissue or for controlling bacterial skin infection is described. The skin cells are irradiated with a low-intensity broad spectrum light at a wavelength of between about 340 to 3,000 nm. The increase in rate of cultivated cells is useful for example to obtain skin-like tissue needed for skin grafts or for promoting healing of skin wounds or lesions. Light-induced skin bacteria control is useful for example in the treatment of bacterial infections of the skin.

The present invention discloses a skin wound stapler, which is characterized in that the both sides of a skin wound (1) are provided with strip-shaped base cloth (2), the base cloth is connected with a plurality of locking devices, each locking device is composed of a support strip (4), latches (5) and a tension belt (3), the upper surface of the support strip is provided with latches (5) at intervals, the lower surface of the support strip is connected with the base cloth, the latches consist of upper latches (9) and lower latches (8), the upper surfaces of the lower latches and the lower surfaces of the upper latches are respectively provided with convex slots and concave slots which are matched mutually, the tension belt penetrates the latches at the both sides of the wound, and the tension belt is regulated and fixed by the locking function of the upper latches and the lower latches, so as to provide the proper suturing force to the wound, further to constitute the skin stapler. The invention is used for suturing the linear or curved wounds, which can effectively shorten the surgical suture time, facilitate the nursing of the post-operative wounds, provide the smooth degree of the wound healing and reduce the scar residues.

The present invention relates to poloxamer compositions and the use thereof for the purpose of treating skin wounds on a human body.

Methods and pharmaceutical compositions for inducing or accelerating a healing process of a damaged skin or skin wound, comprise modulating expression and / or activity of at least two PKC isoforms in skin cells colonizing the damaged skin or skin wound area.

Implantable preparation comprising a material which can be obtained from globin that has been modified, especially chemically, to be, at least partially, soluble at physiological pH, the material being biocompatible, and biodegradable in the organism. The material may be soluble at physiological pH, or insoluble at that pH. The preparation may be in the form of a solution, suspension, paste, gel, film, sponge, powder or granules, or a solid implant. Application in particular to the healing, protection or filling of external skin wounds, the filling of wrinkles and skin flaws, the filling of tissue, as means for fixing prostheses or biomaterials, or means for preventing adhesion.

A system configured to provide feedback regarding fluid parameters in the skin and / or compartments of an individual to facilitate early diagnosis of skin wounds and compartment syndromes.

The use of acidified nitrate as an agent to produce local production of nitrate oxide at the skin surface is described in the treatment of peripheral ischaemia and associated conditions. The dosage form may be in any pharmaceutically acceptable carrier means and comprises an acidifying agent adapted to reduce the pH at the environment. A barrier consisting of a membrane allows diffusions of the nitrate ions while preventing direct contact of the skin and acidifying agent. Amongst the many potential applications for the invention is the management of chronic skin wounds, peripheral ischaemia conditions such as Raynaud's phenomenon. Compositions and methods of use for these applications are described.

The invention discloses a medical bionic transparent film implanting material which is a transparent porous material generated by electrostatic spinning and crosslinking. The thickness of the film ranges from 0.400 mu m to 800 mu m, the transparency of the film ranges from 75.0% to 99.9%, and the film comprises the following components in percentage by weight: 75.00%-95.00% of collagen, 1.50%-15.00% of polysaccharides, 0.01%-3.00% of therapeutic substances, and the balance being water. The film is prepared by an electrostatic spinning method. According to the invention, the technology is simple, the whole process is free of pollution, the transparency of the film is high, and the implanting material has a function of slow releasing on the loaded therapeutic substances, can remarkably improve a human tissue damage repair effect, and can be applied to ocular surface damage membrana tectoria, skin wound dressing, bone tooth defect regeneration guide films and other viscera repair separation films.

A wound dressing that includes two layers for a two part solution to the needs of a healing skin wound. The first step involves a relatively closed system wherein moisture is kept near the skin to promote healing. The second step allows for removal of a top layer of the dressing to reveal a layer with a series of apertures that allows for 100% moisture vapor and oxygen transmission rates to avoid irritation and itching of the skin. At the same time, the bottom layer of the wound dressing maintains a significant outer perimeter that prevents the perimeter migration of microorganisms into the healing wound. The wound dressing can also be used as a means for securing medical instruments, such as intravenous catheters, to the skin of a patient while avoiding the itching and irritation associated with traditional methods.

This invention relates to methods of promoting the healing of skin wounds, products for promoting the healing of skin wounds and processes for making such products. More particularly, this invention relates to layered absorbent dressings which absorb wound exudate in conjunction with additional products for assisting the healing of wounds at each stage of wound healing, as well as methods of using these dressings and methods of making these dressings.

An implantable preparation comprises a material which can be obtained from globin that has been modified, especially chemically, to be, at least partially, soluble at physiological pH. The material is biocompatible, and biodegradable in the organism. The material may be soluble at physiological pH, or insoluble at that pH. The preparation may be in the form of a solution, suspension, paste, gel, film, sponge, powder or granules, or a solid implant. The preparation can be used for the healing, protection or filling of external skin wounds, the filling of wrinkles and skin flaws, the filling of tissue, as a device for fixing prostheses or biomaterials, or as a device for preventing adhesion.

A scar treatment silicone dressing used for attaching onto wound of skin, comprising: a surface layer, a connection layer, a silicone layer, and a protection film. The surface layer is moisture permeable and water resistant thus providing protection function, and on one of its sides is disposed a silicone layer through a connection layer. The silicone layer is provided with penetrating through holes for controlling dissipation of moisture of skin wounds, as such assisting skin exiting perspiration to said surface layer via said through holes, hereby reducing the possibility that the acidic metabolite in perspiration getting in touch with the skin for long period of time in causing irritations / inflammations of the skin; meanwhile, it is also capable of preventing over-dissipation of moisture from the surface of skin, thus it will not adversely affect the repair and reconstruction of the scar tissue.

The invention relates to an alginate-based hydrogel dressing and a preparation method thereof, and belongs to the technical field of medical supplies. Raw materials of the invention are a compound of sodium alginate or other alginates and a thickener, a moisturizer and other functional matters, are subjected to swelling dosing, pre-crosslinking, film coating, spray crosslinking, constant-temperature crosslinking plasticizing and film-covering shear forming, and are then prepared into a three-dimensional water-containing grid structure through covalent cross-linking and ion cross-linking. The medical hydrogel dressing is a topical gel dressing, has good moisturizing performance, toughness and adhesion, is mainly suitable for superficial skin damage, such as cut wound, lacerated wound, scratch, burns, suture wounds and the like, protects skin wound healing of a patient, has effects of easing pain, inhibiting bacteria, resisting inflammation, keeping the wound moist, promoting wound healing, and improving the wound repairing quality, is more suitable for treating bedsore wounds, ulcer wounds and other sites hard to be bound after a surgery, can also be used for non-wound sites, and plays a role of moisturizing.

The present application is concerned with an improved wound dressing for use in the treatment of skin wounds with some level of exudation, especially for use in those wounds which are infected or under risk of being infected by microorganisms.

The invention relates to the cosmetic technology field, and especially relates to a cosmetic or skin care product preparation rich in growth factors and a preparation method therefor. A cosmetic or skin care product preparation rich in growth factors and composed of main ingredients: cell growth factors, micromolecule polypeptides, water, grease, surfactants, humectants, anti-oxidants and preservatives and a preparation method are provided. Through mutual cooperation of ingredients, the composition preparation can accelerate metabolism of skin cells, restore fractured shallow epidermal layer fibrocytes, has protruding rapid restoration function to skin wound surfaces, and has a plurality of functions of whitening, wrinkle removing, calmness, anti-allergy, skin smoothing, anti-wrinkle, brightening, refreshing, anti-aging, anti-radiation, stain prevention and reduction and the like.

The invention relates to hydrogel wound dressing for treating laser cauma and burns and scalds. The active components of the hydrogel wound dressing include an antibacterial agent, a humectant and a stabilizer, wherein the antibacterial agent inhibits adhesion and growth of the wound of laser cauma and surrounding bacteria and can kill various pathogenic bacteria at the cauma part, so as to effectively promote union of the laser cauma. The antibacterial agent adopted by the invention does not generate drug resistance, the humectant can maintain moisture of the wound, promote union of the wound surface, prevent formation of scars and alleviate wound pain. With the adoption of the stabilizer, the hydrogel maintains long-time antibacterial effectiveness. Experiments verify that the hydrogel dressing provided by the invention has the effects of effectively relieving wound pain, controlling local infection, maintaining moisture of wound skins, protecting skins, accelerating and promoting union of wound surface and wound and preventing formation of scars, and can be used for healing laser-burned skin wound surfaces (such as laser mole removal and the like) and wound surfaces of burns and scalds.

An oxygenation and temperature thermal therapy and oxygenation treatment pad with a plurality of air chambers is disclosed for treatment of skin wound tissues. The air chambers are filled and released by a valve assembly that may be separate from or integrated within the blanket. The thermal therapy and oxygenation treatment pad includes a fluid bladder for delivering hot and / or cold therapy to a patient in conjunction with oxygenation. The temperature therapy blanket may also include an air bladder for providing compression. Oxygenation is provided subsequent to initial heating in order to promote oxygen absorption by the wound tissues prior to the cooling thereof which facilitates pulling oxygen into the wound tissues. This Abstract is provided to comply with rules requiring an Abstract that allows a searcher or other reader to quickly ascertain subject matter of the technical disclosure. This Abstract is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. 37 CFR 1.72(b).

The invention discloses a wound nursing dressing containing hyaluronic acid. The dressing comprises hyaluronic acid and salt thereof, and soluble silver salt effective ingredients, wherein the hyaluronic acid comprises high molecular weight hyaluronic acid and low molecular weight hyaluronic acid or oligomeric hyaluronic acid, wherein the high molecular weight hyaluronic acid is excellent in viscoelasticity, moisture retention and hydroscopicity, and the low molecular weight has a remarkable effect of promoting angiogenesis; the hyaluronic acids with two molecular weights both have multiple effects to wound healing, and have the effect of playing quick response and long action; and the soluble silver salt is stable in quality, has a good bacteriostatic effect, and plays a synergetic effect when being compounded with hyaluronic acids with high and low molecular weights. The dressing can be used for disinfection, anti-infection and healing acceleration of various skin wounds, ulcer and the like, and has a remarkable effect.

The invention relates to a chitosan transparent hydrogel wound dressing for medical use, comprising polyacrylic acid (PAA), polyvinyl ketopyrrolidine (PVP) and chitosan, the weight ratio thereof is 4-20:1.5-15:0.15-3; the wound dressing is transparent flake. The preparation method comprises the following steps: respectively configuring chitosan serum, PVP solution and polyacrylate sodium solution; mixing the 3 solutions and adding evocating agent and cross linking agent to the 3 solutions; pouring the mixture into a mould and obtaining the primary product after reaction at the temperature of 40-75 DEG C; adding preservative to the surface of the primary product and drying the product at the temperature of 40 DEG C; obtaining the wound dressing after cutting, ventilated membrane addition, encapsulation and gamma ray sterilization. The wound dressing can be applied to skin wounds, outside body wounds and tissue engineering. The hydrogel wound dressing of the invention has the characteristics of diminishing inflammation and stanching, and having good hydroscopic property, good conformity and the like, as a result, the wound dressing can partially replace the traditional gauze dressing; the preparation method thereof is simple in operation, low in cost, friendly to the environment and high in economic benefits.

Methods for inducing or accelerating a healing process of a damaged skin or skin wounds are described. The methods include administering to the skin cells colonizing the damaged skin or skin wound a therapeutically effective amount of an adipokine, an adipocyte or preadipocyte modulator, adipocytes, preadipocytes, or stem cells, or transforming the skin cells colonizing the damaged skin or skin wound such as to express and secrete an adipokine, thereby inducing or accelerating the healing process of the damaged skin or skin wound.

A method and composition for reducing or eliminating stinging that may accompany application of topical solution of a skin-compatible polymeric material to a skin wound, abrasion, burn or other skin injury. The topical solution may contain one or more skin-irritating chemicals, such as diethyl ether, ethanol, ethyl acetate, methyl acetate, acetone, methyl ethyl ketone and combinations thereof. The method includes: (i) providing a composition that contains between 1% and 10% by weight of the skin-compatible polymeric material dissolved in a liquid medium suitable for human topical use in which the liquid medium includes less than 20% combined weight of skin-irritating chemicals, and at least 45% combined weight of at least one volatile solvent and / or volatile co-solvent, in which the molecules constituting this 45% combined weight portion of the liquid medium contain at least 5 carbon atoms, and the liquid medium has an initial boiling point at 1 atmosphere of greater than 35° C. and less than 150° C., and causes little or no stinging when applied to a skin injury, and (ii) applying the composition to the skin of a patient at the site of the skin injury.

An oxygenation and temperature thermal therapy and oxygenation treatment pad with a plurality of air chambers is disclosed for treatment of skin wound tissues. The air chambers are filled and released by a valve assembly that may be separate from or integrated within the blanket. The thermal therapy and oxygenation treatment pad includes a fluid bladder for delivering hot and / or cold therapy to a patient in conjunction with oxygenation. The temperature therapy blanket may also include an air bladder for providing compression. Oxygenation is provided subsequent to initial heating in order to promote oxygen absorption by the wound tissues prior to the cooling thereof which facilitates pulling oxygen into the wound tissues. This Abstract is provided to comply with rules requiring an Abstract that allows a searcher or other reader to quickly ascertain subject matter of the technical disclosure. This Abstract is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.

The invention provides a medical dressing for protecting skin wounds and promoting repairing, an application of the medical dressing and a preparation method of the medical dressing. The medical dressing comprises a biological plural gel film dressing and a medical polyurethane adhesive film; the biological plural gel film dressing is composed of raw materials of a framework material synthesized by polyanion substances and polycation substances, hyaluronic acid, polypeptide and bonding polypeptide; and the potential of hydrogen (pH) value of the biological plural gel film dressing is 5.8-6.4. The medical dressing for protecting the skin wounds and promoting repairing of the skin wounds has the advantages of wound covering medical dressings, more importantly, by means of synergistic actions of the bonding polypeptide and the hyaluronic acid, the structural designs of medical dressing materials are optimized, and additional growth factors or living cells are not required for enabling the medical dressing materials to have functions of in-situ inducing tissue regeneration and repair.

This invention pertains to therapeutic antibacterial / antifungal-wound healing compositions comprising a therapeutically effective amount of antibacterial agents and / or antifungal agents and / or wound healing composition alone. In one embodiment, the wound healing composition comprises (a) zinc oxide; (b) calcium channel blocker, and (c) fat-soluble vitamins admixed with antibacterial and antifungal agents. The therapeutic antibacterial / antifungal-wound healing compositions may be utilized in a wide variety of pharmaceutical products and administered orally or topically.

The invention discloses a sodium alginate-sodium carboxymethylcellulose-chitosan wound dressing and a preparation method thereof, and relates to a dressing for human body skin wounds. The wound dressing is composed of 1%-1.4% of sodium alginate, 0.6%-1% of sodium carboxymethylcellulose, 0.3%-0.9% of chitosan, 6%-8% of glycerol and the balance of water. The preparation method comprises the following steps: adding sodium alginate and sodium carboxymethylcellulose into water, adding chitosan and acetic acid so as to obtain a uniform solution, and then pouring the uniform solution into a culture dish to perform first freeze drying; then putting the dried material into a CaCl2 solution and an NaOH solution in sequence to soak, performing second freeze drying, soaking in a glycerol aqueous solution, and performing a third freeze drying so as to obtain the product. The preparation technology is simple, the cost is low, the safety and the biocompatibility are better, the characteristics of being high in absorbability, capable of maintaining moist wound condition, low in adhesion, easy to replace and the like are achieved, and wound healing is facilitated.

The invention relates to the technical field of medicines, and in particular relates to a micro-emulsion thermosensitive gel for skin wound healing and a preparation method thereof. The micro-emulsion thermosensitive gel disclosed by the invention is composed of medicines, oil phase, a surfactant, a cosurfactant, a gel matrix and water, wherein the medicines are selected from resveratrol, paeonol and matrine. Proved by animal experiments, the prepared micro-emulsion thermosensitive gel has the characteristics of nearly no irritation to skin, safety in use, large percutaneous infiltration quantity, high percutaneous infiltration rate, long retention time of the micro-emulsion gel in the skin, high medicine concentration in the skin, good slow-release effect and good effect of promoting the healing of skin wound injury. The micro-emulsion thermosensitive gel disclosed by the invention has the advantages of simpleness in preparation method, low cost, convenience and safety in use and capability of effectively promoting the skin wound healing. According to the invention, a novel dosage form is provided for treating the skin wound.