269 results about "Nano emulsion" patented technology

The invention discloses a cationic core-shell PHA nano-emulsion reinforcing agent as well as preparation and application thereof, and belongs to the technical field of papermaking chemicals. The problems that a traditional wet strength agent is poor in environmental protection property and difficult to recycle, and a conventional bio-based material needs high-temperature curing and is high in energy consumption are solved. According to the reinforcing agent, low-MFFT bio-based polyhydroxyalkanoate is used as a core, and a positive ion shell layer with strong positive charges is wrapped outside the core. The method has the core advantages that extra high-temperature curing is not needed, the film can be efficiently formed under the conventional 105 DEG C drying condition, and the energy consumption is remarkably reduced; meanwhile, high dry and wet strength and water resistance are achieved, the treated paper has excellent re-pulping recycling suitability, and the industrial pain point that traditional wet strength paper is difficult to recycle is solved.

The invention relates to the technical field of pharmaceutical preparations, in particular to a multiple nano emulsion adjuvant and a preparation method thereof. The multiple nano emulsion adjuvant is prepared from 2.73 to 6.37 g of an oil phase matrix based on 100 g of a raw material system, 0.10 to 0.25 g of a sterol compound; 0.212 to 0.424 g of a nonionic surfactant; 0.00050 to 0.00200 g of a triterpenoid saponin type active adjuvant; 0.010 to 0.020 g of an anionic polymer modifier; 0.005 to 0.015 g of a cationic polymer modifier; 70-90 g of a buffer solution; the total mass of the raw materials is 100 g. The nano emulsion adjuvant prepared by the invention can be stored for 6 months at 2-8 DEG C under a low sterol condition, the particle size change does not exceed + 5%, no crystallization or layering is generated, and the stability of the active adjuvant is remarkably improved.

The invention discloses a preparation process of a pure plant essential oil disinfectant, and relates to the technical field of disinfectants. The problems that plant essential oil is poor in solubility in a water phase, low in stability and the like are solved. The method specifically comprises the following steps: preparing raw materials; preparing a nano emulsion; preparing a solvent and mixing; constructing a natural stable system to obtain a primary product; filtering and sterilizing; and carrying out sterile filling on the disinfectant finished product. The invention provides a pure plant essential oil disinfectant prepared by dissolving type 1 and 8 melaleuca alternifolia essential oil in water, efficient dispersion is realized through a nano-emulsification and natural stabilization technology so as to form a stable aqueous solution, an amphiphilic structure of soapbark saponin is utilized, aglycone and essential oil terpene form a supramolecular compound, and the stable aqueous solution can be used for sterilizing the melaleuca alternifolia essential oil and the melaleuca alternifolia essential oil and the melaleuca alternifolia essential oil. The technical problems of poor dissolvability and low stability of plant essential oil in a water phase are solved, and the plant essential oil has broad-spectrum antibacterial and antiviral characteristics and can meet the disinfection requirements in multiple fields such as medical treatment, object surface treatment, home furnishing and personal care.

The invention discloses a slow-release antibacterial and antioxidant composite preservative film and a preparation method thereof. The slow-release antibacterial and antioxidant composite preservative film is prepared from a chitosan matrix and Chuzhou chrysanthemum essential oil nano-emulsion loaded in the chitosan matrix, the Chuzhou chrysanthemum essential oil nano-emulsion comprises Chuzhou chrysanthemum essential oil, a surfactant and a cosurfactant, and the average particle size of the Chuzhou chrysanthemum essential oil nano-emulsion is smaller than 200 nm; the composite preservative film has the function of slowly releasing the Chuzhou chrysanthemum essential oil and shows antibacterial and antioxidant activity; the preparation method comprises the following steps: firstly preparing Chuzhou chrysanthemum essential oil into a nano-emulsion by adopting a nano-encapsulation method through a high-pressure homogenization method to form the Chuzhou chrysanthemum essential oil nano-emulsion, then embedding the Chuzhou chrysanthemum essential oil nano-emulsion into chitosan to prepare an active chitosan composite film, and finally applying the antibacterial coating material to food preservation. The antibacterial coating film not only can effectively inhibit pathogenic microorganism infection in berry storage and logistics transportation in a wider spectrum, but also can regulate physiological metabolism of picked berries, delay the senescence process and reduce loss of internal moisture.

The invention discloses a preparation process of a moxidectin pouring solution. The preparation process comprises the following steps: S1, respectively preparing a moxidectin initial solution and a thickener premixed solution; s2, the moxidectin initial solution and the thickener premixed solution are stirred and mixed uniformly at the temperature of 25-35 DEG C to form a mixture A, the stirring speed is 150-250 rpm, and the mixing time is 10-20 min; s3, adding auxiliary materials into the mixture A, and uniformly mixing to form a mixture B; s4, supplementing the second solvent into the mixture B to the total amount, uniformly mixing, and filtering to obtain a moxidectin pouring solution; the method comprises the following steps: dissolving a moxidectin raw material in a first solvent to obtain a moxidectin initial solution, and synthesizing the moxidectin raw material by using biological catalysis; the first solvent is a nano-emulsion formed after homogenization. According to the preparation method, the solubility of the medicament, the stability of the preparation and the transdermal drug delivery efficiency are improved by improving the solvent system and controlling the process in the preparation process of the moxidectin pouring solution.

The invention discloses a multilevel liver targeting drug delivery system based on ionizable amino lipid and a preparation method thereof, the system comprises the following components: target modified ionizable amino lipid, ionizable amino lipid, auxiliary lipid and structural lipid in a molar ratio of (10-30): (30-60): (5-40): (15-55), according to the system, nano lipid particles exist in a water-in-oil-in-water nano emulsion form; wherein the ionizable ammonia lipid is a compound with a structure as shown in a formula (I). The system is suitable for delivering nucleic acid, protein and other active pharmaceutical ingredients to the liver so as to improve the accuracy and treatment effect of drug delivery and reduce the side effects of non-target organs.

The invention discloses a self-emulsifying adjuvant of a vaccine and a preparation method of the self-emulsifying adjuvant, and relates to the technical field of vaccine adjuvants. The adjuvant comprises an oil phase, an emulsifier and a freeze-drying protective agent, the oil phase comprises squalene and tocopherol, the emulsifier comprises polysorbate and a polyoxyethylene-polyoxypropylene block copolymer, and the freeze-drying protective agent comprises sugar and sugar alcohol. The preparation method comprises the following steps: emulsifying an oil phase and a water phase to form a nano-emulsion, and then freeze-drying to obtain freeze-dried powder. The adjuvant has the advantages of small particle size, uniform distribution, high stability, rapid reconstruction and the like, and can effectively maintain active components and improve the immune effect of vaccines.

The invention discloses a nanometer emulsion based on a citrus extract and a preparation method of the nanometer emulsion. The nano-emulsion takes citrus pectin as a main chain, gallic acid, ascorbic acid-phosphate and oleic acid are sequentially grafted, the oleic acid is lipophilic, the rest is hydrophilic, and the amphiphilic pectin can form the whitening nano-emulsion which can be stably stored for a long time. The natural citrus extract is used for replacing traditional synthetic components, has the anti-oxidation, whitening and anti-inflammatory effects, can reduce the skin sensitivity risk, and conforms to the green beauty makeup trend; meanwhile, the oil phase is anchored by a hydrophobic block, steric hindrance is formed by a hydrophilic block, the stability of the emulsion is remarkably improved, and the shelf life is prolonged to 24 months; phenolic acid and ascorbic acid contained in the traditional Chinese medicine composition can effectively scavenge free radicals, inhibit tyrosinase activity, reduce melanogenesis and reduce release of a proinflammatory factor IL-6; the composition is low in cost, environment-friendly, suitable for the fields of cosmetics and medicines and wide in market prospect.

The invention provides a rare ginsenoside high-internal-phase Pickering emulsion microcapsule, a preparation method thereof and application of the rare ginsenoside high-internal-phase Pickering emulsion microcapsule in the aspects of uric acid reduction and kidney protection, and the preparation method comprises the following steps: (1) mixing a pectin aqueous solution and a tannic acid aqueous solution, adjusting the pH value, and stirring to obtain pectin-tannic acid composite sol, namely a water phase; (2) adding rare ginsenoside into the oil, and stirring to fully dissolve the rare ginsenoside to obtain an oil phase; (3) mixing the water phase and the oil phase, stirring, standing and carrying out ultrasonic treatment to obtain a crude emulsion; (4) emulsifying and homogenizing the crude emulsion to obtain crude emulsion; (5) carrying out high-pressure homogenization on the crude emulsion, so as to obtain a rare ginsenoside high-internal-phase Pickering emulsion; and (6) drying the rare ginsenoside high internal phase Pickering emulsion, so as to obtain the rare ginsenoside high internal phase Pickering emulsion microcapsule. The invention solves the problems of low safety, poor stability and low bioavailability of the traditional nano-emulsion, and belongs to the technical field of functional foods.

The invention relates to the technical field of functional drinks, in particular to a polypeptide synergistically strengthened cubilose collagen composite drink with a breast enlarging function and a preparation method of the polypeptide synergistically strengthened cubilose collagen composite drink. The drink contains fish collagen tripeptide, elastin peptide, cubilose peptide, pueraria mirifica isoflavone, red clover isoflavone and saffron crocus extract. A lipidosome delivery system is adopted to entrap polypeptide to form a nano-scale compound, nano-emulsion entraps phytoestrogen, and berry polyphenol and lipidosome-polypeptide form a stable ternary compound. Through the multi-way synergistic effect that phytoestrogen activates a mammary gland estrogen receptor, polypeptide promotes connective tissue collagen synthesis and cubilose peptide activates a growth factor signal, mammary gland development is remarkably promoted, the breast enlarging effect is achieved, the bioavailability reaches 85% or above, and the retention rate of active ingredients stored at normal temperature for 24 months is larger than 90%.

The invention discloses a layered volatilization sleep-aiding essential oil product based on lavender essential oil and sandalwood essential oil and a preparation method of the layered volatilization sleep-aiding essential oil product. The preparation method comprises the following steps: mixing a high-volatility essential oil component and a low-volatility essential oil component with a natural emulsifier according to a specific ratio, carrying out an ultrasonic emulsification technology to obtain a nano-emulsion, and drying the nano-emulsion to prepare the microcapsule essential oil particles. According to the invention, different volatile components are coated by a specific emulsification method to reduce the volatilization loss and improve the stability, and layered slow release with synchronous starting and controllable speed is realized by utilizing the difference between high and low volatility; wherein the high-volatility component is quickly released in the early stage to provide an instant tranquilizing and allaying excitement effect, and the low-volatility component is slowly released in the later stage to provide a continuous sleep aiding effect. The layered volatile sleep-aiding essential oil product based on the lavender essential oil and the sandalwood essential oil provided by the invention is good in stability, has the advantages of rapid effect taking, lasting controlled release, uniform volatilization, good skin compatibility and the like, and can be used for preparing more sleep-aiding and nerve-soothing products.

The present disclosure relates to nanoemulsions of 5-amino-[4-(4-chlorobenzoyl)-3,5-dichlorobenzyl]-1,2,3-triazole-4-carboxamide (carboxy-amido-triazole or CAI), methods of preparing thereof, and their use in the treatment of inflammatory optic neuropathies.

The invention discloses ailanthus altissima extract nano-emulsion and a preparation method and application thereof, the nano-emulsion comprises ailanthus altissima extract, holly essential oil, an emulsifier and water, and the ailanthus altissima extract is ailanthus altissima bark extract; the preparation method comprises the following steps: uniformly mixing the ailanthus altissima extract, the holly essential oil and the emulsifier as an oil phase, dropwise adding water into the oil phase while stirring, and continuously stirring after dropwise adding to obtain the uniform ailanthus altissima extract nano-emulsion. Compared with the ailanthus altissima extract, the ailanthus altissima nano-emulsion has the advantages that the insecticidal effect is obviously improved, the obvious insecticidal effect on various pests is achieved, the plant source pesticide is good in environmental compatibility, diversified in biological activity, safe to higher animals and natural enemies and not prone to generating drug resistance to pests.

The present application relates to a kind of nanodroplet system based on interface crosslinking curcumin and its preparation method, by the crosslinking complexation between gallic acid ester, metal ion, curcumin to construct nanodroplet system.Gallic acid ester is polyphenol compound, contains a large number of phenolic hydroxyl in structure, has strong chelating metal ability, can be complexed with most of trivalent metal ions and divalent excessive metal ions, called metal phenolic network;Metal ions such as copper, iron and other metal ions form complex by electrostatic interaction with the beta diketone group in the structure of curcumin.Therefore, the nanodroplet system constructed by the present application can maintain the chemical stability and light stability of curcumin, and has wide prospect for improving the current food field curcumin low solubility, poor stability and other problems.

The subject matter of the present invention is a perfusion fluid in the form of an oil-in-water PFC nanoemulsion, methods of producing this perfusion fluid, and its use in particular for organ perfusion and as a blood substitute preparation.

The application discloses a preparation method of polyelectrolyte nanoemulsion for frozen meat preservation and an ice-coating method of the polyelectrolyte nanoemulsion, and has the characteristics that the method comprises the following steps: 1) filtering the thawing juice of collected frozen meat, and then performing ultrafiltration centrifugation by using a 8-10 kDa filter membrane; taking the filtrate, and obtaining an antifreeze peptide powder through freeze-drying; 2) slowly adding water-soluble sodium carboxymethyl cellulose into a chitosan solution to make the final mass concentration of the sodium carboxymethyl cellulose be 0.6-1%, and simultaneously adding the antifreeze peptide powder to make the final mass concentration of the antifreeze peptide powder be 6-10%, and then magnetically stirring to obtain a matrix aqueous solution; and 3) adding soybean oil containing essential oil drop by drop into the matrix aqueous solution with a volume of 8-12 times of the soybean oil, homogenizing by using a high-speed homogenizer, and then performing homogenization treatment by using a high-pressure homogenizer, and repeating the homogenization and the homogenization treatment for 3-8 times, so as to obtain the polyelectrolyte nanoemulsion, and the polyelectrolyte nanoemulsion has the advantages of good adhesion, good preservation effect, the ability to improve the quality of the frozen meat and the ability to prolong the shelf life of products.

The present nanoemulsions are a delivery system for virtually any non-opioid active agent for pain, and contain: a hydrocarbon lipid; a perfluorocarbon; water and / or buffered saline; a nonionic surfactant; and optionally a quaternary ammonium compound and / or an additional lipid. Droplets of the non-opioid analgesic formulations have a diameter of 150 nm or less, and preferably range from 90 nm to about 120 nm and have shelf stability for at least twelve months. The nanoemulsions are suitable for a wide variety of routes of administration, including but not limited to IV and parenteral, the latter having particular battlefield and war zone suitability.

The invention relates to a medium-chain triglyceride nano-composite emulsion and a preparation method thereof, and belongs to the technical field of nano-emulsions. The composite emulsion comprises medium chain triglyceride, glycerol, an emulsifying aid and deionized water, an ether esterification CNF is added as a stabilizer, and the composite emulsion is synthesized by a two-step method: firstly esterifying methacryloyl chloride and nano cellulose, then enabling the esterified methacryloyl chloride and nano cellulose to react with sulfhydrylated polyoxyethylene through thiol-ene click reaction initiated by ultraviolet light, and introducing a hydrophilic ether chain. According to the structure, the stabilizer can be firmly anchored on an oil drop interface, and aggregation is prevented through the steric hindrance effect. When the emulsion is prepared, the stabilizer is dispersed in the water phase, then the oil phase is added for preliminary emulsification, and finally high-pressure homogenization treatment is performed. The emulsion prepared by the method is fine and uniform in particle size, obviously improved in stability, not easy to layer at high temperature and under long-term storage, excellent in spreadability and refreshing in skin feeling, and suitable for high-end cosmetic carriers.

The application discloses a non-ionic gemini surfactant for displacement and a preparation method thereof, and a nano-emulsion displacement agent and a preparation method thereof. The nano-emulsion displacement agent comprises the following raw materials in parts by weight: 20-35 parts of a surfactant; 1-10 parts of a nanometer material; 5-10 parts of a dispersing agent; 15-20 parts of a stabilizer; 15-45 parts of an auxiliary agent; and 30-55 parts of an aqueous phase. The surfactant is a complex system of an anionic surfactant and a non-ionic gemini surfactant. The nano-emulsion displacement agent prepared by the application has good temperature resistance and salt resistance, small particle size, can significantly reduce the oil-water interfacial tension, can easily penetrate into the micro-pore throat of a stratum, can displace crude oil from the pore throat, can improve the oil displacement efficiency, and can further improve the crude oil recovery rate.

This invention provides a broad-spectrum antibacterial natural active ingredient nanoemulsion, its preparation method, and its application, relating to the field of food preservation technology. The preparation method of the broad-spectrum antibacterial natural active ingredient nanoemulsion provided by this invention includes the following steps: mixing soy protein isolate and citrate buffer to obtain an aqueous phase solution; mixing thymol, eugenol, ginger essential oil, spearmint oil, and soybean oil to obtain an oil phase solution; mixing the aqueous and oil phase solutions and performing shearing treatment to obtain a crude emulsion; and subjecting the crude emulsion to ultrasonic disruption to obtain the broad-spectrum antibacterial natural active ingredient nanoemulsion. This invention can improve the stability and water solubility of active ingredients such as eugenol, thymol, carvone, limonene, and α-soybeanene, improve their antibacterial properties, and effectively extend the shelf life of refrigerated prepared meat products.

This invention describes of a means of stabilizing lipophilic drugs for long-term storage by incorporating them into a “thermally stabilized nanoemulsion” that has a phase transition temperature that is at or below the body temperature of 37 C and above a storage temperature of 4-8 C. One or more lipid soluble drugs are incorporated into the nanoemulsion at an elevated temperature above the phase transition temperature of the nanoemulsion and then stabilized for extended storage by lowering the temperature to below its phase transition temperature. This causes the nanoemulsion to transform into solid lipid nanospheres entrapping the drug within the solid lipid matrix. Upon rewarming the lipid nanospheres they will reconvert to an oil-in-water nanoemulsion suitable for administration to the patient in need. This invention further discloses disease targeting thermally stabilized nanoemulsions utilizing targeting agents such as antibodies, aptamers, binding peptides, hormones, cytokines and the like, attached to the exterior of the nanodroplets comprising the nanoemulsion.

The application provides a nanoemulsion and a preparation method and application thereof. The total amount of raw materials for preparing the nanoemulsion is 100%, and the raw materials include the following components: 1-40% of a composite surfactant, 1-25% of an oil phase, 1-30% of a co-surfactant, and the balance of a water phase; wherein the mass of the composite surfactant is 100%, and the composite surfactant includes the following components: 5-25% of a biological surfactant, 35-65% of a fatty alcohol polyoxyethylene ether surfactant, 1-20% of dodecyl benzene sulfonic acid and / or sodium salt thereof, 1-20% of oleic acid, and 1-5% of citric acid; the biological surfactant includes one or more than two combinations of sophorolipid, rhamnolipid, trehalose lipid, surfactin, alkyl polyglycoside, phosphatidylcholine, amino acid lipid, saponin, phospholipid, or derivatives thereof; and the average particle size of the emulsion droplets in the nanoemulsion is 1.5-5 nm. The nanoemulsion has excellent recovery performance.

The application discloses a preparation method of a self-emulsifying type wet spinning raw silk oil agent and a preparation method of high-uniformity carbon fibers, and belongs to the technical field of carbon fibers. In the application, polyglycerol and epsilon-caprolactone are catalytically prepared into PG-PCL; then the PG-PCL is reacted with acrylate to obtain acrylated PG-PCL; finally, the PG-PCL, the acrylated PG-PCL and perfluoropolyether acrylate are uniformly dissolved in acetone; then carboxylated cellulose nanocrystals and iron phthalocyanine are added and high-speed shearing emulsification is carried out, and water is gradually added to form a nanoemulsion; and the high-uniformity carbon fibers are obtained by combining a low-temperature preparation method of the carbon fibers. The method synchronously solves the problems of emulsion stability, fiber uniformity and carbonization compatibility, shortens a production cycle, is suitable for high-end fields such as aerospace and new energy vehicles, and has the advantages of high performance and green manufacturing.

This invention discloses a highly stable, endotoxin-free PHA nanoemulsion and its preparation method, belonging to the field of biodegradable polymer material compositions and their processing technology. This nanoemulsion has an endotoxin content of no more than 0.10 EU / g and a median particle size of d... 50 Characterized by a nanoparticle size of 100-200 nm and a PDI not exceeding 0.15, it exhibits long-term storage stability. Its preparation method is a continuous solvent-free process, including melt extrusion, high-pressure thermal emulsification, and deep endotoxin removal steps. This invention resolves the chemical incompatibility between efficient alkaline purification processes and the stable nanoemulsion system by employing specific pH-insensitive cationic polymer emulsifiers and crystallization inhibitors, and also inhibits physical aging, achieving unexpected technical effects. This invention also discloses an O / W type cream containing this nanoemulsion.

The invention relates to the field of skin care products, and discloses a nano-emulsion with high oxidation resistance as well as a preparation method and application of the nano-emulsion. The nano-emulsion is prepared from the following raw materials in percentage by mass: 0.1 to 2.0 percent of antioxidant compound extract, 0.1 to 4.0 percent of vegetable oil, 2.0 to 20.0 percent of saccharides, 0.3 to 8.5 percent of stabilizer and water. The vegetable oil is selected from one or more of camellia oil, sweet almond oil, apricot kernel oil, avocado oil, wheat germ seed oil and baobab oil. The nano-emulsion disclosed by the invention has excellent stability, anti-oxidation effect and biological safety, and can be applied to anti-skin aging products.

The invention discloses a cinnamon essential oil slow-release fresh-keeping pad based on a hydrogel system and a preparation method and application of the cinnamon essential oil slow-release fresh-keeping pad, and relates to the technical field of biology. The hydrogel base material is prepared from nano dialdehyde microfibrillated cellulose and carboxymethyl chitosan; the cinnamon essential oil nano-emulsion is prepared from Tween 80, cinnamon essential oil, starch sodium octenylsuccinate and deionized water. The hydrogel fresh-keeping pad is reasonable in design, combines hydrogel with a natural antioxidant, is suitable for refrigeration and cold-chain circulation after loquat picking, can remarkably inhibit fruit browning, hardening and water loss, keeps fruit quality, solves the problems that a traditional fresh-keeping sheet / pad / paper is single in function, poor in drug effect lasting performance and the like, and has good conversion and application prospects.

The application discloses a kind of nanodroplet based on citrus extract and preparation method thereof.The nanodroplet is grafted with gallic acid, ascorbic acid-phosphate and oleic acid in turn with citrus pectin as main chain, and oleic acid is lipophilic, and the rest is hydrophilic, and amphiphilic pectin can form long-term stable storage whitening nanodroplet.The application replaces traditional synthetic ingredients with natural citrus extract, has antioxidant, whitening and anti-inflammatory effects, can reduce the risk of skin sensitivity, and meets the trend of green beauty;At the same time, the hydrophobic block anchors the oil phase, and the hydrophilic segment forms steric hindrance, which significantly improves the stability of the emulsion and prolongs the shelf life to 24 months;The phenolic acid and ascorbic acid contained therein can effectively scavenge free radicals, inhibit tyrosinase activity, reduce melanin production and reduce the release of pro-inflammatory factor IL-6;It is low in cost and environmentally friendly, suitable for cosmetics and pharmaceutical field, and has broad market prospect.

The application relates to a preparation method of natural cyclic lipopeptide nano-encapsulates with high oil content, and the steps are as follows: natural emulsifiers, glycerol, oil and water are weighed, the natural emulsifiers comprise sodium subtilipetrol and polyglycerol-10 oleate; the natural emulsifiers and the glycerol are mixed and heated and stirred, the oil is added after being dissolved, and a gel phase is obtained; water is added to the gel phase until the gel phase is completely dispersed, and natural cyclic lipopeptide nano-encapsulates are obtained. The compounding and synergistic effect of the sodium subtilipetrol and the polyglycerol-10 oleate is used in the application, compared with two single emulsifiers, the oil loading content is improved and the particle size is reduced. The natural nano-emulsion with high oil content prepared by the application has the advantages of low emulsifier dosage, simple process, small particle size (less than 600 nm), high oil content (more than 20%) of the prepared nano-emulsion, strong stability, high active substance loading content, good penetration effect and the like, is suitable for most liquid oils, and has high application value in the field of cosmetics.

A gas-responsive nano-emulsion separation membrane and its application method, the present application belongs to the field of chemical separation technology, specifically relates to oil-water separation membrane. The separation membrane is woven by polar yarn, the surface of the polar yarn is covered with a polymer coating, the polymer coating is prepared by polymerization reaction of carbon dioxide responsive monomer and hard end monomer; the carbon dioxide responsive monomer is a monomer containing end double bond and tertiary amine response group; the hard end monomer is an unsaturated carbonyl compound containing end double bond; the sum of the warp density and the weft density of the woven is between 300T-400T, the pore size distribution of more than 80-90% of the separation membrane is 0.1-0.3um; the separation membrane is used for separating nano-scale dispersed phase emulsion, the nano-scale dispersed phase emulsion is oil-in-water emulsion or water-in-oil emulsion with dispersed phase particle size of 20nm-50nm. The separation membrane has switchable surface wettability, and can realize on-demand separation of water-in-oil emulsion and oil-in-water emulsion by adjusting the surface wettability.

A method of preparing a flavoring composition and composition thereof for imparting citrus juice flavor, taste, and aroma to food stuffs comprising a nano emulsion comprising a mixture of acids, emulsifiers, essential oils, weighting agents, and a thickening and texturizing agent wherein the composition comprises essential oils at 100 to 200 parts per million (ppm); flavor compound mix (selected from a group of recipes) at 50 to 100 ppm, pectin at 0.5 to 1.0 % by weight or 5,000 to 10,000 ppm among other ingredients specific to the type of citrus fruit to be imparted.