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430 results about "Nano emulsion" patented technology

Nanoemulsions are considered a type of nanomaterial, since they contain nano-sized droplets of drug-loaded oil particles. Nanomedicine research has shown that materials and particles on the nano scale have enhanced cellular uptake properties, through natural cellular mechanisms.

PHA / PVA nanoscale paper-based barrier emulsion as well as preparation method and application thereof

The invention discloses a PHA / PVA nano-scale paper-based barrier emulsion as well as a preparation method and application thereof. The water-based emulsion comprises PHA particles with the average particle size ranging from 100 nanometers to 300 nanometers and PVA, the PHA and the PVA are blended according to a specific proportion, and the PVA serves as a main film forming component and a barrier property contribution component and is blended with the PHA to form the nano-emulsion. The preparation method comprises the following steps: mixing PHA particles with an initial average particle size of 1-100 microns with a PVA aqueous solution, and carrying out high-pressure homogenization and other nanocrystallization means to obtain the nano-emulsion. The emulsion can be coated on the surfaces of paper-based materials such as paper and paperboards, and a barrier coating is formed after the emulsion is dried. The obtained emulsion is small in particle size, good in stability and good in leveling property, a uniform and compact barrier film is easily formed on a paper base, the film has excellent water vapor, oxygen and grease barrier performance, and the material is bio-based, biodegradable and environmentally friendly.
Owner:DU BAI CHENG NEW MATERIAL TECH (SHANGHAI) CO LTD +1

A kind of oxidized hyaluronic acid-PDRN-polypeptide nanoemulsion and preparation method thereof

ActiveCN117017824BCosmetic preparationsAntibacterial agentsTissue repairLayer by layer self assembly
The present invention belongs to the technical field of cosmetic raw materials, and specifically relates to a kind of oxidized hyaluronic acid-PDRN-peptide nanoemulsion and its preparation method. The nanoemulsion comprises oxidized hyaluronic acid, PDRN and polypeptide, and the nanoemulsion is formed by oxidized hyaluronic acid, PDRN and polypeptide through layer-by-layer self-assembly technology. Specifically: positively charged polypeptide is used to wrap negatively charged PDRN to form positively charged composite particles, or negatively charged PDRN is used to wrap positively charged polypeptide to form electrostatic composite particles, and then, the positively charged composite particles or the electrostatic composite particles are further wrapped with oxidized hyaluronic acid as a packaging material, and finally oxidized hyaluronic acid-PDRN-peptide nanoemulsion is formed. The nanoemulsion of the present invention can improve the stability of polypeptides, improve the problems that polypeptide molecules are difficult to penetrate the skin and have low bioavailability, and effectively improve the transdermal rate and stability of PDRN, give play to the tissue repair function of PDRN, further amplify the anti-inflammatory effects of the two, and improve the bioavailability of active ingredients.
Owner:SHAANXI BAIHONG SYNTHETIC BIOTECHNOLOGY CO LTD

A PHA / PVA nano-scale paper-based barrier emulsion and its preparation method and application

The present invention discloses a PHA / PVA nanoscale paper-based barrier emulsion, and its preparation method and application. The aqueous emulsion comprises PHA particles with an average particle size of 100 nanometers to 300 nanometers and PVA, wherein PHA and PVA are blended in a specific ratio, and PVA is blended with PHA as the main film-forming component and barrier performance contributing component to form the nanoemulsion. The preparation method comprises mixing PHA particles with an initial average particle size of 1 micron to 100 microns with a PVA aqueous solution, and processing the nanoemulsion by nano-processing means such as high-pressure homogenization. The emulsion can be applied to paper-based materials, such as paper and cardboard surfaces, and forms a barrier coating after drying. The emulsion obtained by the present invention has small particle size, good stability, good leveling properties, and is easy to form a uniform and dense barrier film on the paper base. The film has excellent water vapor, oxygen and grease barrier properties, and the material is bio-based, biodegradable, and environmentally friendly.
Owner:DU BAI CHENG NEW MATERIAL TECH (SHANGHAI) CO LTD +1

High-stability endotoxin-free PHA nano-emulsion and preparation method thereof

ActiveCN120585676ACosmetic preparationsToilet preparationsEndotoxin removalNanoparticle
The invention discloses a high-stability endotoxin-free PHA nano-emulsion and a preparation method thereof, and belongs to the technical field of biodegradable high polymer material compositions and processing thereof. The nano-emulsion is characterized in that the endotoxin content is not higher than 0.10 EU / g, the median particle size d50 is 100-200 nm, and the PDI is not higher than 0.15, and the nano-emulsion is stable in long-term storage. The preparation method is a continuous solvent-free process and comprises the steps of melt extrusion, high-pressure thermal emulsification and deep endotoxin removal. By adopting the specific pH-insensitive cationic polymer emulsifier and the crystallization inhibitor, the chemical contradiction that an efficient alkaline purification process is incompatible with a nano-emulsion stable system is solved, physical aging is inhibited, and an unexpected technical effect is obtained. The invention also discloses an O / W type cream containing the nano emulsion.
Owner:DU BAI CHENG NEW MATERIAL TECH (SHANGHAI) CO LTD +1

Cationic core-shell PHA (Polyhydroxyalkanoate) nano-emulsion enhancer as well as preparation and application

The invention discloses a cationic core-shell PHA nano-emulsion reinforcing agent as well as preparation and application thereof, and belongs to the technical field of papermaking chemicals. The problems that a traditional wet strength agent is poor in environmental protection property and difficult to recycle, and a conventional bio-based material needs high-temperature curing and is high in energy consumption are solved. According to the reinforcing agent, low-MFFT bio-based polyhydroxyalkanoate is used as a core, and a positive ion shell layer with strong positive charges is wrapped outside the core. The method has the core advantages that extra high-temperature curing is not needed, the film can be efficiently formed under the conventional 105 DEG C drying condition, and the energy consumption is remarkably reduced; meanwhile, high dry and wet strength and water resistance are achieved, the treated paper has excellent re-pulping recycling suitability, and the industrial pain point that traditional wet strength paper is difficult to recycle is solved.
Owner:DU BAI CHENG NEW MATERIAL TECH (SHANGHAI) CO LTD +3

Pro-NANO-emulsions comprising omega 3 and use thereof

The present invention relates to pro-nano-emulsion compositions comprising at least one type of Omega 3 fatty acid capable of converting to nano-emulsion composition having average droplet size of below Ip, typically below 0.5p, and use thereof, particularly as dietary supplement, for preferential delivery of the Omega 3 fatty acid to heart and / or liver tissue of a subject consuming the composition, thereby maintaining normal cardiovascular / hepatic function and / or improving cardiovascular / hepatic disease or disorders.
Owner:HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LTD +1

Multiple nano emulsion adjuvant and preparation method thereof

The invention relates to the technical field of pharmaceutical preparations, in particular to a multiple nano emulsion adjuvant and a preparation method thereof. The multiple nano emulsion adjuvant is prepared from 2.73 to 6.37 g of an oil phase matrix based on 100 g of a raw material system, 0.10 to 0.25 g of a sterol compound; 0.212 to 0.424 g of a nonionic surfactant; 0.00050 to 0.00200 g of a triterpenoid saponin type active adjuvant; 0.010 to 0.020 g of an anionic polymer modifier; 0.005 to 0.015 g of a cationic polymer modifier; 70-90 g of a buffer solution; the total mass of the raw materials is 100 g. The nano emulsion adjuvant prepared by the invention can be stored for 6 months at 2-8 DEG C under a low sterol condition, the particle size change does not exceed + 5%, no crystallization or layering is generated, and the stability of the active adjuvant is remarkably improved.
Owner:JIANGSU WALVAX BIOTECHNOLOGY CO LTD

Preparation method of avocado soup rich in eucommia seeds

The invention discloses a preparation method of avocado soup rich in eucommia ulmoides seeds, which comprises the following steps: modifying chickpea protein isolate (CPI) through dynamic high-pressure microjet (DHPM), assisting grafting modification of CPI and arabinose (AB) by DHPM, preparing nano-emulsion rich in eucommia ulmoides seed oil by using the modified chickpea protein isolate (CPI) as an emulsifier, and adding the nano-emulsion into the avocado soup to improve the fat-soluble nutrient content of the avocado soup.
Owner:ZHENGZHOU UNIVERSITY OF LIGHT INDUSTRY

Preparation process of pure plant essential oil disinfectant

The invention discloses a preparation process of a pure plant essential oil disinfectant, and relates to the technical field of disinfectants. The problems that plant essential oil is poor in solubility in a water phase, low in stability and the like are solved. The method specifically comprises the following steps: preparing raw materials; preparing a nano emulsion; preparing a solvent and mixing; constructing a natural stable system to obtain a primary product; filtering and sterilizing; and carrying out sterile filling on the disinfectant finished product. The invention provides a pure plant essential oil disinfectant prepared by dissolving type 1 and 8 melaleuca alternifolia essential oil in water, efficient dispersion is realized through a nano-emulsification and natural stabilization technology so as to form a stable aqueous solution, an amphiphilic structure of soapbark saponin is utilized, aglycone and essential oil terpene form a supramolecular compound, and the stable aqueous solution can be used for sterilizing the melaleuca alternifolia essential oil and the melaleuca alternifolia essential oil and the melaleuca alternifolia essential oil. The technical problems of poor dissolvability and low stability of plant essential oil in a water phase are solved, and the plant essential oil has broad-spectrum antibacterial and antiviral characteristics and can meet the disinfection requirements in multiple fields such as medical treatment, object surface treatment, home furnishing and personal care.
Owner:HEILONGJIANG ZHONGNONG TIANSHUN ECOLOGICAL AGRICULTURE DEVELOPMENT CO LTD

Ultrasonic microreactor

The utility model discloses an ultrasonic microreactor which is formed by directly attaching an ultrasonic transducer and a microreactor, the ultrasonic microreactor is formed by connecting a plurality of fluid microchannel reaction layers in series; the fluid micro-channel reaction layer is formed by alternately connecting a plurality of thin channels and thick channels; a reaction layer turbulent flow chip is arranged in the middle of the thick channel; under the synergistic effect of ultrasound and the microreactor, the ultrasonic microreactor has higher energy density and more accurate sound field and flow field regulation and control capability, and can solve the problems that channels are easy to block and the like, so that nano-emulsion with uniform particle size can be continuously prepared, and the efficiency of an emulsification process and the quality of an emulsion product are improved.
Owner:GUANGDONG UNIV OF TECH +1

Camellia composition nano-emulsion with anti-aging and repairing effects on fatigue skin as well as preparation and application of camellia composition nano-emulsion

The invention belongs to the technical field of plant extraction and cosmetics, and particularly relates to camellia composition nano-emulsion with anti-aging and repairing effects on fatigue skin as well as a preparation method and application of the camellia composition nano-emulsion. The camellia flower extract, the camellia leaf extract, the camellia seed oil, the camellia seed extract and the PEG-40 hydrogenated castor oil are used as raw materials and are compounded according to a certain dosage to prepare the nano-emulsion, and the nano-emulsion has multiple effects of moisturizing, tightening, removing acnes and the like; the skin care product solves the problems that a conventional skin care product is not remarkable enough in fatigue muscle improvement effect, not quick enough in effect and insufficient in pertinence, and the skin is restored to be tender, moisturized and bright.
Owner:SHANGHAI FOREST CABIN BIOLOGICAL-TECH CO LTD

Slow-release antibacterial antioxidant composite preservative film and preparation method thereof

The invention discloses a slow-release antibacterial and antioxidant composite preservative film and a preparation method thereof. The slow-release antibacterial and antioxidant composite preservative film is prepared from a chitosan matrix and Chuzhou chrysanthemum essential oil nano-emulsion loaded in the chitosan matrix, the Chuzhou chrysanthemum essential oil nano-emulsion comprises Chuzhou chrysanthemum essential oil, a surfactant and a cosurfactant, and the average particle size of the Chuzhou chrysanthemum essential oil nano-emulsion is smaller than 200 nm; the composite preservative film has the function of slowly releasing the Chuzhou chrysanthemum essential oil and shows antibacterial and antioxidant activity; the preparation method comprises the following steps: firstly preparing Chuzhou chrysanthemum essential oil into a nano-emulsion by adopting a nano-encapsulation method through a high-pressure homogenization method to form the Chuzhou chrysanthemum essential oil nano-emulsion, then embedding the Chuzhou chrysanthemum essential oil nano-emulsion into chitosan to prepare an active chitosan composite film, and finally applying the antibacterial coating material to food preservation. The antibacterial coating film not only can effectively inhibit pathogenic microorganism infection in berry storage and logistics transportation in a wider spectrum, but also can regulate physiological metabolism of picked berries, delay the senescence process and reduce loss of internal moisture.
Owner:CHUZHOU UNIV

Plant compound essential oil as well as preparation method and application thereof

PendingCN120360145AFruit and vegetables preservationBiotechnologyPenicillium digitatum
A preparation method of plant compound essential oil comprises the following steps: preparing mixed powder from dried lemon slices, mint and litsea coreana, carrying out carbon dioxide supercritical extraction, and collecting an extract; the preparation method comprises the following steps: dropwise adding a carboxymethyl-beta-cyclodextrin solution into a mixture of eugenol and thymol, carrying out ultrasonic treatment to obtain an ultrasonic mixed solution, standing, centrifuging, collecting supernate, and drying to obtain a white powdery inclusion compound; and adding lecithin, Tween 80, disodium pyrophosphate and deionized water into the extract, heating and stirring, continuing to add the inclusion compound, homogenizing to obtain a nano-emulsion, adding gelatin and propylene glycol, heating and preserving heat, and cooling to obtain the plant composite essential oil. The compound essential oil disclosed by the invention has antibacterial and antioxidant effects, and has relatively strong antibacterial ability on botrytis cinerea and penicillium germs, and the DPPH free radical scavenging rate is greater than or equal to 90%. According to the invention, the active ingredients of the essential oil are wrapped by carboxymethyl-beta-cyclodextrin and synergistically embedded by lipidosome through a nano-embedding technology to realize slow release, so that the antioxidant and antibacterial properties are effectively prolonged.
Owner:CHONGQING UNIV OF ARTS & SCI

Preparation process of moxidectin pouring solution

The invention discloses a preparation process of a moxidectin pouring solution. The preparation process comprises the following steps: S1, respectively preparing a moxidectin initial solution and a thickener premixed solution; s2, the moxidectin initial solution and the thickener premixed solution are stirred and mixed uniformly at the temperature of 25-35 DEG C to form a mixture A, the stirring speed is 150-250 rpm, and the mixing time is 10-20 min; s3, adding auxiliary materials into the mixture A, and uniformly mixing to form a mixture B; s4, supplementing the second solvent into the mixture B to the total amount, uniformly mixing, and filtering to obtain a moxidectin pouring solution; the method comprises the following steps: dissolving a moxidectin raw material in a first solvent to obtain a moxidectin initial solution, and synthesizing the moxidectin raw material by using biological catalysis; the first solvent is a nano-emulsion formed after homogenization. According to the preparation method, the solubility of the medicament, the stability of the preparation and the transdermal drug delivery efficiency are improved by improving the solvent system and controlling the process in the preparation process of the moxidectin pouring solution.
Owner:JINAN GUANGSHENGYUAN BIOTECH

Dendrobium huoshanense polysaccharide nanoemulsion immunologic adjuvant and preparation method thereof

The invention discloses a dendrobium huoshanense polysaccharide nanoemulsion immunologic adjuvant and a preparation method thereof. The dendrobium huoshanense polysaccharide nanoemulsion immunologic adjuvant is prepared from the following raw materials in percentage by mass: 0.1%-2.0% of dendrobium huoshanense polysaccharide, 20%-30% of a surfactant, 5%-10% of a cosurfactant, 5%-10% of an oil phase and the balance of deionized water. The preparation method of the nano-emulsion is simple and easy to implement, equipment is easy to control, the cost is low, and the obtained nano-emulsion is small in droplet particle size, high in stability and capable of improving the spleen lymphocyte proliferation activity of immunocompromised mice. The nanoemulsion can significantly improve the immunomodulatory activity of dendrobium huoshanense polysaccharide, and has the potential of developing immunopotentiators, thereby promoting the development and utilization of traditional Chinese medicine resources and active components thereof.
Owner:WEST ANHUI UNIV

High-performance shellac nano emulsion paint protein film and preparation method thereof

PendingCN120059270AShellac coatingsFlexible coversPolymer sciencePreservative
The invention discloses a high-performance shellac nano emulsion paint protein film and a preparation method thereof. The preparation method comprises the following steps: S1, preparing a protein film-forming solution; s2, pouring the protein film-forming liquid prepared in the step S1 on a plane template, casting to form a film, drying and taking down to form the film; s3, the shellac ethanol solution and polyethylene glycol are subjected to high-pressure homogenization, and shellac nano emulsion paint liquid is prepared; and S4, uniformly brushing the shell-lac nano emulsion paint solution prepared in the step S3 on two surfaces of the protein film in the step S2, and drying to obtain the shell-lac nano emulsion paint protein film. The preservative has the beneficial effects that the preservative is easy to biodegrade, free of environmental pollution, good in mechanical property, high in heat stability, high in water, light and oxygen blocking capacity and good in antibacterial and antioxidant effect, food spoilage bacteria can be effectively inhibited, oxygenolysis of nutritional ingredients in food can be slowed down, the preservative has good preservation performance, the food quality can be guaranteed, and the shelf life of the food can be prolonged.
Owner:TIANJIN MODERN VOCATIONAL TECH COLLEGE

Preparation method and application of novel amphiphilic cellulose carboxymethyl cellulose palmitate

The invention belongs to the technical field of preparation of modified cellulose carboxymethyl cellulose and nano-emulsion, and particularly relates to a preparation method of novel amphiphilic cellulose carboxymethyl cellulose palmitate, which comprises the following steps: S1, preparing palmitoleic acid from palm oil as a raw material, and further preparing palmitoleic acid into palmitoleic anhydride; and S2, reacting palmitoleic anhydride obtained in the step S1 with carboxymethyl cellulose, and purifying after the reaction is finished to obtain the carboxymethyl cellulose palmitate. According to the preparation method, ester bonds on palmitoleic acid anhydride and hydroxyl groups on carboxymethyl cellulose are replaced by utilizing the prepared novel palmitoleic acid anhydride derivative through ester exchange reaction, so that the amphipathic carboxymethyl cellulose palmitate is obtained. The novel amphiphilic cellulose carboxymethyl cellulose palmitate synthesized by the invention is green in reaction process and high in reaction activity of palmitic anhydride, and provides a basis for subsequent application in the aspect of self-assembly entrapment.
Owner:SOUTH CHINA AGRICULTURAL UNIVERSITY

Edible oil-in-water nanoemulsion formulations for preharvest treatment and / or postharvest preservation of fruits or vegetables

They are prepared by a high energy method (e.g. by sonication) from: an oily solution of edible oils (e.g. high-oleic sunflower oil) as solvent, with melatonin (e.g. 100 μM) and edible fat-soluble antioxidant agents (e.g. 100 μM α-tocopherol), and an aqueous solution of edible water-soluble stabilizing agents (e.g. dextrin 1% w / v). These formulations, applied externally (e.g. by spraying) are useful for preharvest application and / or postharvest preservation of fruits or vegetables, particularly of stone fruits, and specifically of sweet cherries. In two varieties of sweet cherries and two varieties of plums, preservations with the formulations are significantly better than those reached with aqueous solutions of melatonin, or with a commercial formulation, or in the absence of treatment.
Owner:UNIV DE BARCELONA

Preparation method of candy containing sodium alginate-whey protein composite wall material

The invention provides a preparation method of candies containing a sodium alginate-whey protein composite wall material. The preparation method comprises the following steps: dissolving sodium alginate and whey protein, and then adding active ingredients and the like to prepare a nano-emulsion; performing spray drying to obtain microcapsule powder; after the candy matrix is boiled, microcapsule powder and nano silicon dioxide aerogel are mixed in stages; and finally, carrying out surface coating and ultraviolet curing. The method mainly achieves the following breakthroughs: firstly, a triple protection system is formed, and the problem of survival of probiotics is solved; 2, synergistic release of flavor and functional components is realized; and thirdly, the adaptability problem of the composite wall material is solved, the stability is improved, and the moisture demand contradiction is solved.
Owner:中山市瑞美食品有限公司

Long-acting cool and refreshing resident paste based on compound matrix slow release and preparation method of long-acting cool and refreshing resident paste

The invention discloses a long-acting cool and refreshing lingering paste based on compound matrix slow release and a preparation method thereof, and belongs to the technical field of cosmetics. The ointment body comprises 20-24 parts of beewax, 35-40 parts of a substance with an HLB (Hydrophile-Lipophile Balance) value of 12-15, 28-35 parts of a freshener and 5-7 parts of a plant extract composition. The plant extract is embedded into the matrix in the form of nano emulsion by combining staged temperature control with a nano emulsion technology. The invention has the following effects: by regulating and controlling the proportion of the beewax and the esters with high HLB (Hydrophile Lipophile Balance) value, a honeycomb porous structure is formed, and the body temperature triggered slow release of high-concentration cooling components is realized; through a low-temperature gradient process, staged temperature control (melting-> 40 DEG C emulsification) is combined with a nano-emulsification technology, and the activity of volatile components is retained (the retention rate gt is 98%). The product provided by the invention has the advantages that the cooling feeling lasts for 4-6 hours, the irritation is obviously lower than that of similar products, and the product is suitable for non-face resident type cooling and refreshing nursing for adults.
Owner:ZHANGZHOU MINYI BIOTECHNOLOGY CO LTD

Multi-stage liver-targeted drug delivery system based on ionizable amino lipid and preparation method of multi-stage liver-targeted drug delivery system

The invention discloses a multilevel liver targeting drug delivery system based on ionizable amino lipid and a preparation method thereof, the system comprises the following components: target modified ionizable amino lipid, ionizable amino lipid, auxiliary lipid and structural lipid in a molar ratio of (10-30): (30-60): (5-40): (15-55), according to the system, nano lipid particles exist in a water-in-oil-in-water nano emulsion form; wherein the ionizable ammonia lipid is a compound with a structure as shown in a formula (I). The system is suitable for delivering nucleic acid, protein and other active pharmaceutical ingredients to the liver so as to improve the accuracy and treatment effect of drug delivery and reduce the side effects of non-target organs.
Owner:YANGTZE RIVER DELTA MEDICAL ADVANCED TECHNOLOGY INNOVATION CENTER

High-stability acer truncatum seed oil nano-emulsion and preparation method thereof

The invention belongs to the technical field of food, and particularly relates to a high-stability acer truncatum seed oil nano-emulsion and a preparation method thereof. The composition comprises the following raw materials in parts by weight: 15-25 parts of acer truncatum seed oil, 0.56-2.3 parts of an emulsifier, 2-4 parts of a processing aid and 70-85 parts of water, the emulsifier comprises polyglycerol fatty acid ester, Tween 80 and sucrose fatty acid ester. The prepared nano-emulsion is high in grease content and small in particle size, the average particle size is 200 nm, and the nano-emulsion can have good stability after being placed at normal temperature for 30 d, still has high nervonic acid content and does not deteriorate.
Owner:江苏菌钥生命科技发展有限公司

Reverse osmosis membrane as well as preparation method and application thereof

The invention relates to a reverse osmosis membrane and a preparation method and application thereof.The preparation method of the reverse osmosis membrane comprises the following steps that oil, a surfactant and water are mixed to prepare an oil-in-water type nano-emulsion, the surfactant comprises a nonionic surfactant, the average particle size of the oil-in-water type nano-emulsion is 80-200 nm, and the polydispersity index is smaller than or equal to 0.3; an aqueous solution of inorganic metal salt and an oil-in-water type nano-emulsion are sequentially placed on the same surface of a supporting film, dendrites are formed through heat treatment, and the mass ratio of the inorganic metal salt to the oil-in-water type nano-emulsion is 1: 50-1: 30; and preparing a polyamide separation layer on the surface of the support membrane on which the dendrites are distributed through reverse interfacial polymerization to obtain the reverse osmosis membrane. When the reverse osmosis membrane prepared by the preparation method is applied to water treatment, high desalination rate can be maintained, and meanwhile, high water flux is achieved.
Owner:HANGZHOU WATER TREATMENT TECH DEV CENT +1

Degradable defoaming agent as well as preparation method and application thereof

The invention belongs to the technical field of defoaming agents, and particularly relates to a degradable defoaming agent as well as a preparation method and application thereof. The degradable vegetable oil acid amide in the defoaming agent is easily dispersed in liquid, so that the surface tension of the liquid is reduced; the polyol fatty acid ester can form insoluble particles for defoaming; the nano-emulsion stabilizing aid physically and efficiently defoams by adsorbing gas, and has a thickening effect; fatty alcohol can be quickly diffused to a foam interface, so that the surface tension is reduced, and a quick defoaming effect is achieved. The prepared degradable defoaming agent is free of silicone oil residues, biodegradable in bio-based component and environmentally friendly, the fatty alcohol and the degradable vegetable oleic acid amide can conduct defoaming in time, the nano emulsion stabilizing additive and the fatty acid ester can inhibit the foam regeneration effect, the lauric acid diethanol amine and the Tween 80 can improve the compatibility and dispersity of all the components of the defoaming agent, and the defoaming effect is good. Through the synergistic effect of all the components, the foam inhibitor has excellent degradability, dispersibility and foam inhibition when being applied to paint and ink.
Owner:JIANGSU SAIOUXINYUE DEFOAMER

Micro-nano bubble and bubble generator prepared from micro-nano emulsion

The invention relates to the technical field of micro-nano bubbles, and particularly discloses a bubble generator prepared from micro-nano bubbles and micro-nano emulsion, the bubble generator comprises a shell, the shell comprises a first shell and a second shell, the first shell is connected with the second shell, the first shell is divided into a liquid inlet cavity and a mixing cavity, and the liquid inlet cavity is communicated with the mixing cavity; a plurality of connecting holes are formed between the liquid inlet cavity and the mixing cavity; a first through hole is formed in the second shell, and a cutting block is arranged on the inner wall of the second shell; the spiral guide block is arranged in the first through hole; the back-flushing mechanism comprises a back-flushing shell, a back-flushing channel and a pressure pump, and the back-flushing channel is arranged in the second shell; and the one-way flow limiting mechanism comprises a steel ball, a flow limiting groove and a limiting net. The micro-nano bubble generator overcomes the defects that in the prior art, a micro-nano bubble generator is insufficient in generation effect and difficult to clean, disassemble, assemble and maintain, and the outflow speed of micro-nano bubbles or micro-nano emulsion is difficult to control.
Owner:SHANGHAI WEITAIKE ENVIRONMENTAL TECH CO LTD

Metformin hydrochloride-loaded PLGA (poly (lactic-co-glycolic acid)) nanoparticle material as well as preparation method and application thereof

The invention belongs to the technical field of medicines, and relates to a metformin hydrochloride-loaded PLGA (poly (lactic-co-glycolic acid)) nanoparticle material as well as a preparation method and application thereof. The preparation method comprises the following steps: carrying out first shear emulsification on a metformin hydrochloride aqueous solution and an organic solution containing a first emulsifier and PLGA (poly (lactic-co-glycolic acid)) to obtain a water-in-oil primary emulsion; carrying out second shear emulsification on the primary emulsion and an aqueous solution containing a second emulsifier to obtain a water-in-oil-in-water type crude emulsion; homogenizing and emulsifying the crude emulsion to obtain a W1 / O / W2 nano-emulsion; and removing the organic solvent from the nano-emulsion, centrifuging and drying to obtain the nano-emulsion. The preparation method disclosed by the invention not only has relatively high reproducibility for preparing the nano-particles, but also obviously reduces the average size of the obtained nano-particles, improves the bioavailability of the medicine, and simultaneously keeps the uniform dispersity and high biocompatibility of the nano-particles.
Owner:SHANDONG UNIV

Self-emulsifying adjuvant of vaccine and preparation method of self-emulsifying adjuvant

The invention discloses a self-emulsifying adjuvant of a vaccine and a preparation method of the self-emulsifying adjuvant, and relates to the technical field of vaccine adjuvants. The adjuvant comprises an oil phase, an emulsifier and a freeze-drying protective agent, the oil phase comprises squalene and tocopherol, the emulsifier comprises polysorbate and a polyoxyethylene-polyoxypropylene block copolymer, and the freeze-drying protective agent comprises sugar and sugar alcohol. The preparation method comprises the following steps: emulsifying an oil phase and a water phase to form a nano-emulsion, and then freeze-drying to obtain freeze-dried powder. The adjuvant has the advantages of small particle size, uniform distribution, high stability, rapid reconstruction and the like, and can effectively maintain active components and improve the immune effect of vaccines.
Owner:JIANGSU WALVAX BIOTECHNOLOGY CO LTD

Paper pulp-based hydroxyethyl cellulose antibacterial composite film as well as preparation method and application thereof

The invention relates to a paper pulp-based hydroxyethyl cellulose antibacterial composite film as well as a preparation method and application thereof. The preparation method comprises the following steps: (1) preparing paper pulp-based hydroxyethyl cellulose; (2) preparing a peppermint essential oil nano-emulsion; and (3) preparing the paper pulp-based hydroxyethyl cellulose antibacterial composite film. The average thickness of the paper pulp based hydroxyethyl cellulose antibacterial composite film provided by the invention is 0.205 + / -0.017 mm, and the density is 0.59 + / -0.05 g / cm < 3 >. Hydroxyl in paper pulp base HEC and carboxyl and hydroxyl of SA form a multiple hydrogen bond network; pO is used as a hydrophobic plasticizer and generates interfacial tension with a hydrophilic SA / HEC matrix, and tiny liquid drops or agglomerates are easily formed in the film forming process; ca < 2 + > and carboxylate radicals in SA form ionic bonds through electrostatic interaction to generate a calcium alginate gel network, so that the tensile strength of the paper pulp-based hydroxyethyl cellulose antibacterial composite film reaches 6.1 MPa, the water vapor permeability is 5.32 * 10 <-10 > g.m <-1 >. S <-1 >. Pa <-1 >, and the paper pulp-based hydroxyethyl cellulose antibacterial composite film has a remarkable inhibition effect on growth of penicillium oxalicum.
Owner:QILU UNIVERSITY OF TECHNOLOGY (SHANDONG ACADEMY OF SCIENCES)

Nanoemulsions for internal humectation of mycelium-based textiles

PendingUS20250066991A1Natural fibresBiotechnologyMicrobiology
Described herein are oil-in-water (o / w) nanoemulsions for internal humectation of mycelium-based textiles using fatty acids of vegetable origin and / or their synthetic derivatives and non-ionic surfactants. These nanoemulsions may be used as fatliquoring solutions in materials based on fungal mycelium, bacterial recombinant proteins, plant-based textiles, and / or other materials used as animal leather substitutes, including its potential use as environmentally friendly (e.g., “green”) and cost-effective fatliquoring alternative for animal leather. Also described are methods and apparatuses for scaling up, recovering, and reusing nanoemulsions. The nanoemulsion fatliquoring compositions and methods described herein may reduce frictional forces, improve tensile strength and elongation at break, introduce softness, and protect mycelium-based textile material against cracking.
Owner:SPORA CAYMAN HLDG LTD

Nano-emulsion based on citrus extract and preparation method of nano-emulsion

The invention discloses a nanometer emulsion based on a citrus extract and a preparation method of the nanometer emulsion. The nano-emulsion takes citrus pectin as a main chain, gallic acid, ascorbic acid-phosphate and oleic acid are sequentially grafted, the oleic acid is lipophilic, the rest is hydrophilic, and the amphiphilic pectin can form the whitening nano-emulsion which can be stably stored for a long time. The natural citrus extract is used for replacing traditional synthetic components, has the anti-oxidation, whitening and anti-inflammatory effects, can reduce the skin sensitivity risk, and conforms to the green beauty makeup trend; meanwhile, the oil phase is anchored by a hydrophobic block, steric hindrance is formed by a hydrophilic block, the stability of the emulsion is remarkably improved, and the shelf life is prolonged to 24 months; phenolic acid and ascorbic acid contained in the traditional Chinese medicine composition can effectively scavenge free radicals, inhibit tyrosinase activity, reduce melanogenesis and reduce release of a proinflammatory factor IL-6; the composition is low in cost, environment-friendly, suitable for the fields of cosmetics and medicines and wide in market prospect.
Owner:HUBEI ZHONGKANG ZHONGSHENG BIOTECHNOLOGY CO LTD