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Compound gentamycin sulfate soluble powder and preparation method thereof

A gentamicin sulfate and soluble technology, which is applied in powder delivery, pharmaceutical formulations, organic active ingredients, etc., can solve problems such as difficulty in diagnosis by farmers’ technicians, difficulties in diagnosis and treatment, and inconvenient treatment for farmers, so as to improve the resistance Pathogenic ability, reducing the probability of bacterial resistance, and the effect of reducing the probability of drug resistance

Inactive Publication Date: 2010-03-17
TIANJIN SHENGJI GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Now due to the widespread use of a single antibiotic drug, the pathogen has strong drug resistance. In addition, the disease is not easy to distinguish what kind of pathogen is caused, and it is difficult for farmers or related technical personnel to diagnose. If it is a compound infection of multiple pathogens, this It brings greater difficulties to diagnosis and treatment, often brings great inconvenience to the treatment of farmers, and causes great losses

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Take by weighing 3kg of gentamicin sulfate after sieving, 15kg of acetylmethaquine, 3kg of colistin sulfate, 32kg of vitamin K, and 77kg of anhydrous glucose and fully mix for 1 hour. Compound gentamicin sulfate soluble powder for acute enteritis.

Embodiment 2

[0019] Take by weighing 15kg of gentamicin sulfate after sieving, acetylmethaquine 5kg, colistin sulfate 15kg, vitamin K32kg, anhydrous glucose 63kg and fully mix 1 hour, after mixing, obtain the present invention for the treatment of porcine bacteria Compound gentamicin sulfate soluble powder for acute enteritis.

Embodiment 3

[0021] Take by weighing 5 kg of gentamicin sulfate after sieving, 12 kg of acetylmethaquine, 12 kg of colistin sulfate, 32 kg of vitamin K, and 69 kg of anhydrous glucose and fully mix for 1 hour. Compound gentamicin sulfate soluble powder for acute enteritis.

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PUM

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Abstract

The invention discloses a compound gentamycin sulfate soluble powder and a preparation method thereof, aiming at providing the compound gentamycin sulfate soluble powder and the preparation method thereof, which is used for treating pig bacterial enteritis and has the advantages of fast effect, safe use, small side effect and drug resistance ratio reduction of pathogenic bacteria. The compound gentamycin sulfate soluble powder comprises the following components in weight percent, 3% to 15% of gentamycin sulfate, 5% to 15% of maquindox, 3% to 15% of colistin sulphate, 2% of vitamin K3, and thebalance water. The invention adopts three antimicrobial components of the gentamycin sulfate, the maquindox and the colistin sulphate; the gentamycin sulfate and the colistin sulphate are difficult toabsorb when being eaten, and can kill the pathogenic bacteria through contact so as not to strengthen burden to pig bodies caused by drug; the maquindox is easy to absorb when being eaten, and is widely distributed in the bodies so as to effectively kill bacteria in the blood. The gentamycin sulfate, the maquindox and the colistin sulphate are combined for use so as to effectively kill the pathogenic bacteria, and greatly reduce the drug resistance ratio of the pathogenic bacteria causing the pig bacterial enteritis; and the vitamin K3 has the functions of stopping and restraining blooding.

Description

technical field [0001] The invention relates to a compound gentamicin sulfate soluble powder for treating porcine bacterial enteritis and a preparation method thereof. Background technique [0002] Porcine bacterial enteritis is a type of infectious disease caused by Escherichia coli, Shigella, Salmonella, Listeria, etc. The main clinical features are diarrhea, yellow, gray, yellow-green, brown and other colored feces, and sometimes excretion The water sample or mushy feces have bleeding phenomenon, the condition is very similar, the sick pig is easy to dehydrate, and the mortality rate is high. [0003] Now due to the widespread use of a single antibiotic drug, the pathogen has strong drug resistance. In addition, the disease is not easy to distinguish what kind of pathogen is caused, and it is difficult for farmers or related technical personnel to diagnose. If it is a compound infection of multiple pathogens, this Bring bigger difficulty to diagnosis and treatment, often...

Claims

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Application Information

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IPC IPC(8): A61K38/12A61K9/14A61K47/26A61P31/04A61P1/00A61K31/7036A61K31/498A61K31/122
Inventor 徐克福
Owner TIANJIN SHENGJI GRP CO LTD
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