Compound colistin sulfate soluble powder for treating lamb dysentery and preparation method thereof

A colistin sulfate, soluble technology, applied in the field of compound colistin sulfate soluble powder and its preparation, can solve the problems of not being able to treat well, not being able to quickly stop diarrhea, slow onset of action and the like, and improving the cure rate , reduce losses, easy to achieve effect

Inactive Publication Date: 2010-02-24
TIANJIN SHENGJI GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing medicines for treating lamb dysentery, such as colistin sulfate soluble powder and sulfathiazole sodium soluble powder, have a slow onset speed due to a process of sterilization. During the sterilization process, diarrhea cannot be stopped quickly, and lambs often develop Severe dehydration can cause other diseases and lead to death, but cannot be treated well

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] (1) Sieve colistin sulfate, sulfathiazole sodium, atropine sulfate, vitamin K, and anhydrous glucose through 80-mesh sieve respectively, and set aside.

[0020] (2) Weigh 2 kg of sieved colistin sulfate, 20 kg of sulfathiazole sodium, 0.05 kg of atropine sulfate, and 0.2 kg of vitamin K, and fully mix them in a V-shaped mixer.

[0021] (3) Add 77.75 kg of sieved anhydrous glucose into the mixture of colistin sulfate, sodium sulfathiazole, atropine sulfate and vitamin K, fully mix in a common mixer, discharge, and pass through an 80-mesh sieve The compound colistin sulfate soluble powder for treating lamb dysentery of the present invention is obtained.

Embodiment 2

[0023] (1) Sieve colistin sulfate, sulfathiazole sodium, atropine sulfate, vitamin K, and anhydrous glucose through 80-mesh sieve respectively, and set aside.

[0024] (2) Weigh 10 kg of sieved colistin sulfate, 5 kg of sulfathiazole sodium, 0.5 kg of atropine sulfate, and 0.2 kg of vitamin K, and mix them fully in a V-shaped mixer.

[0025] (3) Add 84.3 kg of sieved anhydrous glucose into the mixture of colistin sulfate, sodium sulfathiazole, atropine sulfate and vitamin K, fully mix in a common mixer, discharge, and pass through an 80-mesh sieve The compound colistin sulfate soluble powder for treating lamb dysentery of the present invention is obtained.

Embodiment 3

[0027] (1) Sieve colistin sulfate, sulfathiazole sodium, atropine sulfate, vitamin K, and anhydrous glucose through 80-mesh sieve respectively, and set aside.

[0028] (2) Weigh 4 kg of sieved colistin sulfate, 15 kg of sulfathiazole sodium, 0.3 kg of atropine sulfate, and 0.2 kg of vitamin K and fully mix them in a V-shaped mixer.

[0029] (3) Add 80.5 kg of sieved anhydrous glucose into the mixture of colistin sulfate, sodium sulfathiazole, atropine sulfate and vitamin K, fully mix in a common mixer, discharge, and pass through an 80-mesh sieve The compound colistin sulfate soluble powder for treating lamb dysentery of the present invention is obtained.

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PUM

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Abstract

The invention discloses compound colistin sulfate soluble powder for treating lamb dysentery and a preparation method thereof and aims to provide the compound colistin sulfate soluble powder which hasa quick therapeutic effect on lamb dysentery, has efficacy in secondary infection bacteria and is convenient to use, and the preparation method which has a simple process and is easy to implement. The powder comprises the following components in percentage by weight: 2 to 10 percent of colistin sulfate, 5 to 20 percent of sulfathiazole sodium, 0.05 to 0.5 percent of atropine sulfate, 0.2 percentof vitamin K, and the balance of anhydrous dextrose. The soluble powder is a compound preparation of the combination of four medicaments, wherein the colistin sulfate and the sulfathiazole sodium areantibacterial for killing pathogens, the atropine sulfate controls diarrhea, reduces water loss and accelerates the treatment speed, and the vitamin K prevents and treats intestinal tract bleeding; and the four medicaments are mixed together reasonably so that the powder has a quick response, treats both symptoms and root causes, and can reduce the losses of raisers. The compound colistin sulfatesoluble powder is soluble powder, is soluble in milk, is used for feeding lambs through the milk and is more convenient to use.

Description

technical field [0001] The invention relates to a compound colistin sulfate soluble powder for treating lamb dysentery and a preparation method thereof. Background technique [0002] Lamb dysentery is a unique disease of lambs. It is caused by Clostridium welchii, and some mixed infections with Escherichia coli, enterococcus, and salmonella are more serious. It is mainly characterized by severe diarrhea and ulcers in the small intestine. [0003] The disease mainly occurs in the lamb stage, and the lamb will soon die due to dehydration due to its poor physique. Existing medicines for treating lamb dysentery, such as colistin sulfate soluble powder and sulfathiazole sodium soluble powder, have a slow onset speed due to a process of sterilization. During the sterilization process, diarrhea cannot be stopped quickly, and lambs often develop Severe dehydration can cause other diseases and lead to death, which cannot be treated well. Contents of the invention [0004] The pre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/14A61K38/12A61K31/426A61K31/46A61K31/122A61P1/12A61P31/04
Inventor 徐克福
Owner TIANJIN SHENGJI GRP CO LTD
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