Medicinal composition for treating rhinitis

A composition and drug technology, applied in the direction of drug combination, drug delivery, pharmaceutical formulation, etc., can solve the problems of slow onset of action and easy drug-induced rhinitis

Inactive Publication Date: 2011-01-19
徐宏模
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The onset of these drugs is relatively slow, and it often takes 5-7 days to take effect. The side effects include nasal dryness, etc., and it is easy to cause drug-induced rhinitis.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Mix commercially available benzoline hydrochloride nasal drops, gentamicin sulfate injection, ribavirin injection, dexamethasone sodium phosphate injection, and chlorpheniramine maleate injection to make nasal Spray so that the following amounts of active ingredient are contained per 10 ml of liquid:

[0034] 5mg benzoline hydrochloride,

[0035] 50 mg gentamicin sulfate,

[0036] 50mg ribavirin,

[0037] 5 mg dexamethasone sodium phosphate,

[0038] 2 mg chlorpheniramine maleate.

Embodiment 2

[0040] Mix commercially available benzoline hydrochloride nasal drops, gentamicin sulfate injection, ribavirin injection, dexamethasone sodium phosphate injection, and chlorpheniramine maleate injection to make drops Nasal solution such that the following amounts of active ingredient are contained per 10 ml of liquid:

[0041] 1mg benzoline hydrochloride,

[0042] 20 mg gentamicin sulfate,

[0043] 50mg ribavirin,

[0044] 1 mg dexamethasone sodium phosphate,

[0045] 1 mg chlorpheniramine maleate.

Embodiment 3

[0047] Mix commercially available benzoline hydrochloride nasal drops, gentamicin sulfate injection, ribavirin injection, dexamethasone sodium phosphate injection, and chlorpheniramine maleate injection to make nasal Spray so that the following amounts of active ingredient are contained per 10 ml of liquid:

[0048] 10 mg benzazoline hydrochloride,

[0049] 50 mg gentamicin sulfate,

[0050] 50mg ribavirin,

[0051] 2 mg dexamethasone sodium phosphate,

[0052] 10 mg chlorpheniramine maleate.

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PUM

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Abstract

The invention discloses a medicinal composition, which comprises pharmaceutically effective dose of tolazoline hydrochloride, gentamycin sulfate, ribavirin, dexamethasone sodium phosphate, chlorphenamine maleate and a pharmaceutical carrier. The medicinal composition can be used for treating various acute or chronic rhinitis, sinusitis, purulent rhinitis, rhinitis sicca, atrophic rhinitis, allergic rhinitis and the like.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating rhinitis, in particular to nasal congestion, runny nose, dry nose, nasal The medicinal composition has good curative effect on symptoms such as odor, headache and dizziness. Background technique [0002] Acute and chronic rhinitis, sinusitis, atrophic rhinitis, allergic rhinitis, rhinitis sicca, etc. are clinically common multiple diseases, mainly including nasal congestion, runny nose, dry nose, nasal odor, headache and other symptoms, causing great harm to patients Pain and discomfort. These diseases are often related to the stimulation of harmful dust and gas. In recent years, with the development of industry and the intensification of air pollution, the incidence of these diseases has been increasing year by year. At present, the medicines for clinically treating these diseases include ephedrine normal saline solution, oxymetazoline hydrochloride spray and the like. The onset of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7056A61K31/7036A61K31/661A61K31/4402A61K31/4174A61K9/12A61K9/00A61P11/02
Inventor 徐宏模
Owner 徐宏模
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