Compound common andrographis herb injection for treating high fever of pigs and preparation method thereof
A technology for compound andrographis paniculata and injection, which is applied in the directions of medical preparations, antipyretics, and pharmaceutical formulations containing active ingredients, can solve the problems that diseases cannot be well controlled, pathogens cannot be accurately determined, and treatment time is not timely, etc. To achieve the effect of reducing the drug resistance of pathogenic microorganisms, enhancing the function of phagocytic cells, and reducing the number of drugs
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Embodiment 1
[0020] (1) Take 25L of water for injection, add Andrographis paniculata extract 3kg, stir to dissolve, then add anhydrous sodium bisulfite 0.2kg, ammonium chloride bethanecholine 0.05kg, EDTA-2Na0.01kg, stir until all dissolve.
[0021] (2) Get 30L of water for injection, add 0.5kg of hydrochloric acid, after stirring evenly, add ofloxacin 4.5kg, after stirring and dissolving, add 1.5kg of gentamicin sulfate, stir and dissolve;
[0022] (3) Take Tween-801kg in a water bath and heat to 60°C, and mix well with 0.5kg of zedoary oil.
[0023] (4) Combine the prepared solution of step (1) and step (2), after stirring evenly, add Sulpyrine 30kg, after stirring and dissolving, mix evenly with the solution obtained from step (3), add water for injection to 100L, stir evenly, keep for 15-20min, adjust the pH value to 5.00-7.00 with 40% sodium hydroxide solution by mass percent concentration or 10% volume percent hydrochloric acid solution, and prepare it for use after the liquid is cl...
Embodiment 2
[0025] (1) Take 25L of water for injection, add Andrographis paniculata extract 7kg, stir to dissolve, then add anhydrous sodium bisulfite 0.2kg, ammonium chloride bethanecholine 0.05kg, EDTA-2Na0.01kg, stir until all dissolve.
[0026] (2) Get 30L of water for injection, add 0.5kg of hydrochloric acid, after stirring evenly, add ofloxacin 1.5kg, after stirring and dissolving, then add gentamicin sulfate 6kg, stir and dissolve;
[0027] (3) Take Tween-801kg in a water bath to 60°C, mix well with zedoary oil 1.5kg.
[0028] (4) Combine the solution prepared by step (1) and step (2), add and stir evenly, then add 8 kg of Sulpyrine, stir and dissolve, mix evenly with the solution obtained by step (3), add injection Water to 100L, stir evenly, keep for 15-20min, adjust the pH value to 5.00-7.00 with 40% sodium hydroxide solution by mass percent concentration or 10% volume percent hydrochloric acid solution, and prepare it after the liquid medicine becomes clear Compound Androgra...
Embodiment 3
[0030] (1) Take 25L of water for injection, add Andrographis paniculata extract 4kg, stir to dissolve, then add anhydrous sodium bisulfite 0.2kg, ammonium chloride bethanecholine 0.05kg, EDTA-2Na0.01kg, stir until all dissolve;
[0031] (2) Get 30L of water for injection, add 0.5kg of hydrochloric acid, after stirring evenly, add ofloxacin 4kg, after stirring and dissolving, then add gentamicin sulfate 2kg, stir and dissolve;
[0032] (3) Take Tween-801kg in a water bath to 60°C, mix well with zedoary oil 1.5kg.
[0033] (4) Combine the solutions obtained in steps (1) and (2), add and stir evenly, then add 25 kg of Sulpyrine, stir and dissolve, mix evenly with the solution obtained in step (3), add injection Water to 100L, stir evenly, keep for 15-20min, adjust the pH value to 5.00-7.00 with 40% sodium hydroxide solution by mass percent concentration or 10% volume percent hydrochloric acid solution, and prepare it after the liquid medicine becomes clear Compound Andrographis...
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