The present invention discloses a handheld fluorescent
endoscopic imaging device and method based on a coaxial
optical path, which relates to the technical field of
optical imaging, and comprises a light homogenizing mechanism, a light modulating mechanism, a
beam splitter prism, a light transmitting mechanism, a color camera and a near-
infrared camera. The excitation light emitted by the light homogenizing mechanism enters the
beam splitter prism through the light modulating mechanism, and the excitation light of a set
wavelength band enters the light transmitting mechanism after passing through the
beam splitter prism to excite the fluorescent
signal of human tissue, and the mixed
white light signal and fluorescent
signal enter the beam splitter prism through the light transmitting mechanism to perform light separation, the
white light signal enters the color camera to obtain a
color image, and the fluorescent signal enters the near-
infrared camera to obtain a fluorescent image; the handheld fluorescent
endoscopic imaging device and method not only reduce the difficulty of the
assembly process and
image alignment, but also can easily realize the pixel-
level fusion of the fluorescent image and the
color image; in addition, the device as a whole is in a handheld and portable form, occupies a small space, is not restricted by the medical environment, and improves the application scope and flexibility.