79results about How to "Little pain" patented technology

A system for extracting a bodily fluid sample (e.g., an interstitial fluid [ISF] sample) and monitoring an analyte therein includes a disposable cartridge and a local controller module. The disposable cartridge includes a sampling module adapted to extract a bodily fluid sample and an analysis module adapted to measure an analyte (e.g., glucose) in the bodily fluid sample. The local controller module is in electronic communication with the disposable cartridge and is adapted to receive and store measurement data from the analysis module. An ISF extraction device includes a penetration member configured for penetrating and residing in a target site of a user's skin layer and, subsequently, extracting an ISF sample therefrom. The device also includes a pressure ring(s) adapted for applying pressure to the user's skin layer in the vicinity of the target site. The device is configured such that the pressure ring(s) is capable of applying pressure in an oscillating manner whereby an ISF glucose lag of the ISF sample extracted by the penetration member is mitigated. A method for extracting ISF includes providing an ISF fluid extraction device with a penetration member and a pressure ring(s). Next, a user's skin layer is contacted by the pressure ring(s) and penetrated by the penetration member. An ISF sample is then extracted from the user's skin layer while pressure is being applied in an oscillating manner by the pressure ring(s). The oscillating pressure mitigates an ISF glucose lag of the extracted ISF sample extracted.

An interstitial fluid (ISF) extraction device includes a penetration member configured for penetrating a target site of a user's skin layer and, subsequently, residing in the user's skin layer and extracting an ISF sample therefrom and at least three concentrically-arranged pressure rings, each adapted for applying pressure to the user's skin layer in the vicinity of the target site while the penetration member is residing in the user's skin layer. In addition, the ISF extraction device is configured such that (i) the pressure rings apply pressure in an oscillating manner with asymmetric deployment and retraction cycles and (ii) only one of the at least three concentrically-arranged pressure rings is deployed at a time, thereby mitigating an ISF glucose lag of the ISF sample extracted by the penetration member.

A device for sensing analyte concentration, and in particular glucose concentration, in vivo or in vitro is disclosed. An optical conduit, preferably an optical fiber has an optical system at the proximal end of the optical conduit. A sensing element is attached to the distal end of the optical conduit, and comprises at least one binding protein adapted to bind with at least one target analyte. The sensing element further comprises at least one reporter group that undergoes a luminescence change with changing analyte concentrations. Optionally, the sensing element includes reference groups with luminescence properties that are substantially unchanged by variations in the analyte concentrations.

Systems and methods are provided for extracting a bodily fluid sample (e.g., an interstitial fluid sample) and monitoring an analyte therein. Certain of the systems include a a penetration member configured for penetrating and residing in a target site of a user's skin layer and, subsequently, extracting a fluid sample therefrom. The system also includes a pressure ring(s) adapted for applying pressure to the user's skin layer in the vicinity of the target site. The system is configured such that the pressure ring(s) is capable of applying pressure in an oscillating manner. Certain methods include penetrating the skin and applying pressure to the skin in an oscillating manner.

Apparatuses and methods to generate high frequency shock waves in a controlled manner. The generated shock waves can be delivered to certain cellular structures of a patient for use in medical and / or aesthetic therapeutic applications. The shock waves can be configured to impose sufficient mechanical stress to the targeted cells of the tissue to rupture the targeted cells. Embodiments of the apparatuses and methods of the present invention provide targeted rupturing of specific cells without damaging side effects such as cavitation or thermal degradation of surrounding non-targeted cells.

The invention relates to a stem cell repairing material as well as a preparation method and application thereof. The stem cell repairing material comprises a stem cell and a cell carrier, wherein the stem cell is an autologous adipose-derived mesenchymal stem cell (ADSC) with a concentration of 105-108 / ml, and the cell carrier is autoserum, normal saline (0.9%) or a glucose injection (5%). In the invention, adopted seed cells are prepared through separating and purifying autologous adipose tissues of patients, thereby avoiding the ethical disputes and the immunological rejection. The material drawing of the adipose tissues can be performed by using an instrument suction method, which is simple in operation and can bring less traumas and pains to the patients. The cell carrier used in the invention is the autoserum, normal saline (0.9%) or glucose injection (5%), therefore, the cell carrier mixed with mesenchymal stem cells and other ingredients can be injected into the patents by virtue of syringes. By using the stem cell repairing material provided by the invention, the operation process is simple, no scar is left, and the wounds and pains for the patients are avoided, therefore, the stem cell repairing material can be easily accepted by the patients.

A blood collecting needle, which comprises: a needle hub; a human-body puncturing needle tube provided at one side of the needle hub; and a plug-body puncturing needle tube provided at the other side of the needle hub, wherein an outer diameter of a tip of the human-body puncturing needle tube and an outer diameter of a tip of the plug-body puncturing needle tube are different from each other.

The invention refers to a puncturing device for generating a puncturing wound by means of a replaceable lancet that comprises a coupling element for transmitting a torque, whereby the puncturing device comprises a lancet drive which, for a puncture, transmits a torque to an inserted lancet that is coupled to the lancet drive by means of its coupling element such that the inserted lancet performs a puncturing motion in the form of a rotational motion about a geometric axis. According to embodiments of the invention, the geometric axis extends through the coupling element. The invention also refers to a lancet supply ribbon comprising lancets for such device and lancets comprising a lancet body having a lancet tip, whereby the lancet body, for coupling to a lancet drive of a puncturing device, comprises a coupling element by means of which the lancet can be made to perform a rotational motion and has a test field for assaying a body fluid sample to which a body fluid sample can be supplied only after the lancet tip has been pulled out of a puncturing wound that has been generated.

A medical instrument, in particular a hysteroscope, has a shaft part (12) having a first shaft and an optical system having a second shaft (40), in which the shaft part (12) and optical system can be displaced with respect to one another along the shafts thereof such that, in a first position, the second shaft (40) of the optical system extends beyond the first shaft of the shaft part (12) on the distal side and that, in a second position, a distal end (23) of the first shaft of the shaft part (12) comes to rest approximately level with a distal end (41) of the second shaft (40) of the optical system.

This adhesive includes a copolymer that includes monomer units represented by (a-1), (a-2), (a-3), and (a-4) described below, and the following content is contained among all of the monomers which constitute the copolymer:(a-1) 5 to 45 wt % of an alkyl(meth)acrylate;(a-2) 0.01 to 10 wt % of a (meth)acrylate having a hydroxyl group or an allyl ether having a hydroxyl group;(a-3) 50 to 78 wt % of an alkoxyalkyl (meth)acrylate;(a-4) 1 to 25 wt % of an alkoxypolyalkylene glycol mono(meth)acrylate or an alkoxypolyalkylene glycol allyl ether.

The invention discloses a medicine and a treatment method thereof for the eradication of acne. The medicine comprises externally applied acne removing ointment and orally taken acne removing capsules. The invention is characterized in that: fire acupuncture technology is used together with the medicine for face acne removing treatment, and the acupuncture positions are acne parts on the face and the Feiyu acupuncture point on the back. Therein the externally applied acne removing ointment comprises the following components by weight: 10 grams of gingko, 60 grams of oldenlandia, 15 grams of red sange root, 10 grams of tree peony bark, and 15 grams of wild chrysanthemum. The orally taken acne removing capsules comprise the following components by weight: 20 grams of honeysuckle flower, 8 grams of weeping forsythia, 20 grams of taraxacum, 20 grams of corydalis, 20 grams of figwort, 8 grams of muscardine silkworm, 8 grams of dittany, 8 grams of flavescent sophora root, 8 grams of broom cypress fruit, 9 grams of ledebouriella root, 8 grams of schizonepeta, 8 grams of wild rue, 8 grams of pepper mint, and 8 grams of cicada slough. By the invention, externally applied and orally taken Chinese traditional medicines are both used together with the fire acupuncture treatment method, so acne is removed thoroughly and pain feeling is alleviated by one fold compared with that by the prior acne acupuncture. Moreover, no pigment marks are left, the treatment effect is remarkable, and the aim of removing acne thoroughly is achieved.

The invention discloses a rechargeable particle catheter. The rechargeable particle catheter includes a catheter body, the catheter body is provided with a charge-in channel and a bag which surrounds the catheter body, one end of the charge-in channel is provided with a valve, the other end of the charge-in channel is communicated with the bag, the bag is provided with radioactive particles, and when the bag inflates, the inflated bag cannot extrude a drainage cavity. The rechargeable particle catheter can be widely used in obstructed or narrow cavities and tracts such as esophagi, stomach and intestines, bile ducts, nephric ducts and vena cave vessels in human bodies, and is wide in application prospect and high in application value. In the process of treating a patient, the catheter only needs to be introduced once, gas charging or liquid charging can be repeatedly conducted on the bag many times, after tumor treatment reaches an expected effect, gas discharging or liquid discharging can be conducted on the bag and then the particle catheter is taken out; multiple operations are not needed, the treatment process is simplified, treatment effects are ensured, the pain of patients is slight, wounds are small, and the rechargeable particle catheter is more acceptable to the patients.

The invention provides a silica gel vacuum sealing drainage dressing, and belongs to the technical field of medical equipment. The silica gel vacuum sealing drainage dressing solves the technical problem that an existing silica gel vacuum sealing drainage dressing is poor in drainage effect. The silica gel vacuum sealing drainage dressing comprises a dressing body. A drainage structure which can discharge percolate under the effect of negative pressure is connected to the dressing body. The silica gel vacuum sealing drainage dressing is characterized in that the dressing body comprises a silica gel layer which can be attached to a human body, through holes are evenly distributed in the silica gel layer, a liquid storage and filter layer and an absorption structure are sequentially arranged on the silica gel layer, the liquid storage and filter layer has the storage and filter functions, and the absorption structure has the percolate absorption function. The silica gel vacuum sealing drainage dressing can be used for processing a small amount of percolate at a postoperative incision, the drainage effect is good, wounds can be prevented from bleeding, and the silica gel vacuum sealing drainage dressing has the advantages of accelerating wound healing, decreasing the number of dressing change times and saving resources.

An object of the present invention is to provide an automatic injection device that allows setting of conditions of puncture according to the thickness of a syringe needle, the puncture depth, and so forth to reduce pain in the puncture and reduce the impact in the puncture to allow alleviation of anxiety and fear of a patient. An automatic injection device of the present invention has a syringe holder that holds a syringe attachably and detachably, a first drive unit that causes the syringe holder holding the syringe to advance to perform puncture by a syringe needle, and a control unit that controls the first drive unit to control the puncture speed.

The invention relates to a subcutaneous medicine controllable release biological needle and a preparation method thereof. By adopting the biological needle, a medicine can be controlled to being released subcutaneously with slight pain, and in addition, the medicine can be administrated by a patient self. The biological needle comprises a needle shell part and a needle core part, wherein the needle shell part is made of a soluble polymer material; the needle core part is composed of accumulated medicine carrier microspheres. The biological needle is sufficient in mechanical property to puncture into skin and is rapidly dissolved to release medicine carrier microspheres carried by the biological needle, and the medicine carrier microspheres carried by the biological needle can be degraded subcutaneously to release the medicine. By adopting the subcutaneous medicine controllable release biological needle provided by the invention, a liver first-pass effect caused by an orally taken slowrelease tablet can be avoided, in addition, the defect that a subcutaneous implanting agent needs to be operated by a medical operator manually can be avoided, and both medicinal effects and economy can be greatly improved.

The invention discloses an establishment method and application of a tumor classification and identification model, belongs to the field of medical disease diagnosis, aims at the problems that samplepreprocessing is complex and time-consuming due to need of location and collection of tumor focus specimens in current pathological diagnosis, small tumor tissues such as early tumor, small residual diseases and circulating tumor cannot be screened diagnosed in the prior art, and provides the establishment method of the tumor classification and identification model. The method is established basedon a plasma emission spectrum of a biological liquid sample, and is combined with chemometrics and a machine learning classification algorithm. The model established through the method can be integrated into a tumor diagnosis and screening instrument, and a rapid and accurate method for large-scale tumor screening and diagnosis of the early tumor and precancerous lesion stage diseases is provided.

The disclosure claims a lumbar interbody fusion cage for treating lumbar spondylolisthesis via a lateral approach. The lumbar interbody fusion cage comprises a supporting frame body, wherein upper and lower blades are mounted on the upper and lower end surfaces of the supporting frame body, a distracting component for driving the upper and lower blades to axially distract along a lumbar interbody and an orthotopic moving component for driving the upper and lower blades to move along the lumbar interbody back and forth are mounted in the supporting frame body, the upper and lower blades respectively extend to form lateral lobes, fixing holes through which fixing nails penetrate are formed on the lateral lobes, the fixing nail of the upper lateral lobe penetrates backward from bottom to top in a slanting way to give a certain rear thrust to the slipped lumbar vertebrae and help reduction of the lumbar spondylolisthesis, and the fixing nailing of the lower lateral lobe penetrates forward from top to bottom to give a forward thrust to the lumbar vertebrae and help the reduction of the lumbar spondylolisthesis. The lumbar interbody fusion cage can solve both an intervertebral spacing and dislocation arisen from forward and backward lumbar spondylolisthesis, has easy operation and small pain to patients, and is safer and more reliable.

The invention relates to a minimally invasive embedded shape memory interbody fusion cage used for spine surgery. The minimally invasive embedded shape memory interbody fusion cage is of a frame-type hollow structure and is composed of multiple stand column shafts, front beams, side beams, memory deformation side beams, memory deformation front beams, multiple shaft peripheral rings and an open window. The front beams, the side beams, the memory deformation side beams and the memory deformation front beams are connected with the shaft peripheral rings through clamping groove structures and raised head structures, and the shaft peripheral rings of different layers are arranged on the corresponding stand column shafts in a sleeving mode, wherein the memory deformation side beams and the memory deformation front beams are made of medical titanium-nickel memory alloy with a shape memory function. The minimally invasive embedded shape memory interbody fusion cage can enter an intervertebral space through an existing tiny channel and has the advantages of being small in wound, less in pain, rapid in recovery, few in complication and the like; after the minimally invasive embedded shape memory interbody fusion cage is spread, the contact area of the interbody fusion cage and an upper end plate and a lower end plate of a vertebral body can be increased, more sclerotin can be implanted, and the fusion rate is increased.

A chiropractic apparatus that is not only easily portable, but also enables even a chiropractor not having a high level skill to perform easily a safe, correct and effective adjustment of any bone of a patient without causing a pain. The chiropractic apparatus includes: a chiropractic adjuster means containing a thrust member having a thrust head and a release-surface means attached to the chiropractic adjuster means, the release-surface means having a surface for forming a release surface. When a longitudinal forward thrust is applied to the thrust member so as to give a thrust to a body surface, the release-surface means and the thrust head are subjected to relative movement with respect to each other, whereby a release surface including the surface for forming a release surface is formed around the thrust head, the release surface having at least a part thereof placed in contact with the body surface.

The invention relates to a biliary tract inner support drainage tube and belongs to medical apparatuses and instruments. The biliary tract inner support drainage tube comprises a support drainage tube and a guiding wire placed in the support drainage tube. One end of the support drainage tube is in an oblique-face shape. Side through holes are evenly distributed in the tube wall of the support drainage tube. The support drainage tube and the guiding wire are used for replacing a T-shaped tube for being used in operative treatment of a patient with choledocholithiasis, after the choledocholith is fully taken out, the primary suture of the common bile duct is carried out without placing the traditional T-shaped tube, so operation time is shortened, operation difficulty is lowered, operation equipment cost is lowered, patient hospital staying time is shortened, hospital staying cost is lowered, postoperative complications are reduced, the patient can be recovered quickly, what is more important, the support drainage tube can be excreted out of the body along with excrement in about one week after operation, so that the patient does not need to suffer from the pain caused by long-term T-shaped tube retention, a series of complications caused by T-shaped tube placing are completed avoided, scars after operation become small, and accordingly the operation becomes more minimally invasive. If the biliary tract inner support drainage tube can be used widely and clinically, great benefit will be brought to the patient.

The invention discloses a decoction for treating blood deficiency intestinal dryness constipation and a preparation method thereof. Radix angelica sinensis is used for enriching blood and lubricating intestines; through the combination of traditional Chinese medicine ingredients of cistanche salsa, polygonum multiflorum, fructus cannabis and black sesame, the decoction has effects on various types of constipation and is good in treatment effect, rapid in effect and thorough in treatment; the applied raw material medicines are low in price and easy to obtain; the decoction has the advantages of being convenient and easy to manufacture, economical and practical; radix angelica sinensis is used for enriching blood and lubricating intestines; through the combination of traditional Chinese medicine ingredients of cistanche salsa, polygonum multiflorum, fructus cannabis and black sesame, the effects of enriching blood and lubricating intestines, relieving patient pains and relieving economic burdens are achieved.

A medicinal product (10) is for the care of an individual having at least one injury such as a burn wound or a skin abrasion, in particular with a large surface area. The product includes at least one functional surface (12, 12′, 14) to at least partially cover the injury and / or to fix the medicinal product (10) to the individual. At least one functional surface (12, 12′) includes stem parts (18) protruding from the surface. The free end-faces of the stem parts form an adhesion section able to adhere at least partially to the individual and / or to a further functional surface (12′), predominantly by Van der Waals forces.

A disposable optical format for lancing the skin of a patient and harvesting blood to determine blood chemistries such as glucose level includes a housing with openings defining an optical path. A translucent hollow capillary tube with multiple planar sides and an end cleaved to a sharp edge is mounted in the housing. The sides of the tube are formed of an optical material such as fused silica. Significantly less pain, high probability of blood harvesting and improved overall test time are achieved with integrating the lance, harvest and analysis operation.

The present invention relates to a negative pressure device, comprising: a hollow needle assembly including: a hollow needle adaptor, the hollow needle adaptor has an axial through hole, a proximal connector, a distal connector and a flange between the proximal connector and the distal connector, and at least one hollow needle, each of the at least one hollow needle has a tip and an axial through hole and is in fluid communication with the proximal connector of the hollow needle adaptor; a host machine, the host machine comprises a control module and a vacuum pump; and an exhaust pipe, the exhaust pipe is in fluid communication with the host machine and the distal connector of the hollow needle adaptor.

A levorotatory oxiracetam freeze-drying powder injection is prepared from the following raw and auxiliary materials by weight percentage: 35-41% of levorotatory oxiracetam, 23-30% of L-serine, 18-28% of mannitol, 5-12% of sodium glutamate, 3-10% of methionine and 1-3% of benzyl alcohol through the steps of concentration, dilution, freeze-drying and capping. According to the prepared levorotatory oxiracetam freeze-drying powder injection, an impurity level is increased less in a preparation process; the impurity level is only increased by 0.03%; the product has a fixed shape; a bottle spraying phenomenon does not occur in a freeze-drying preparation process; the product is good in uniformity and low in impurity level; characters of an upper layer and a lower layer are consistent; the total impurity level of the freeze-drying powder injection is less than 0.28%; the stability is good; a shelf life is up to 24 months; a pain feeling of a patient is milder in an injection process; and the patient is good in compliance.

The invention discloses a novel semiconductor laser medical heating regulation and control method based on a semiconductor laser output mode. According to the semiconductor laser medical heating regulation and control method, each cycle mainly consists of a heating period and a cooling period, laser radiation is stopped in the cooling period, and heating is boosted to realize an effective treatment temperature in a wave manner in the heating period of each cycle. By adopting the novel semiconductor laser medical heating regulation and control method, a semiconductor laser chip is allowed to output laser with relatively high peak power, so that the requirements on laser medical power can be met through a relatively small amount of laser chips, and the cost is lowered; in addition, the cooling waiting time is shortened, the working efficiency is improved, and meanwhile the ache of a patient can be effectively alleviated.

The invention relates to a locking and external fixation device used for treatment of tibial fractures, pertaining to the technical field of medical equipment. The device comprises a rectangular frame body and multiple screws. Multiple threaded holes are transversely formed in the rectangular frame body. The screws are screwed into the threaded holes. The threaded holes in the frame body match threads of the screws so that the effect of connecting the frame body with the screws is achieved. The locking and external fixation device used for treatment of tibial fractures has following beneficial effects: the locking and external fixation device belongs to the concept of external fixation and therefore a wound is small with little bleeding; a cut is reduced by times and only 3 to 4 cm in size and the scar is small and attractive; operative complications are increasingly reduced; due to the external fixation, the risk of a secondary operation is lowered; medical cost is saved for a patient; the device is made by light-weight material such as stainless steel, titanium alloy and the like; compared with a conventional external fixation frame, the frame body of the locking and external fixation device is small in size and low in weight and cause little harm to a patient and help the patient recover; damage to a pin track is little; complications of the pin track are fewer; the device is not easily loosened and loses efficacy; and safety of the operation is enhanced.

The invention relates to a medical device for stopping bleeding in an oppressing manner after the cutting operation of tonsil. The medical device comprises oppressing hemospheres capable of stretching an oral tonsillar pit and wrapped with hemostatic sponge and a supporting mat disposed at cheek outside the mouth and provided with adhesive, wherein the hemospheres are connected with the supporting mat by virtue of a V-shaped arm and provided with an adjusting apparatus capable of adjusting a clamping and oppressing force. The hemospheres can be in a ball shape or a rugby shape, and the hemostatic sponge wrapping the hemospheres are spongy or fiber hemostatic materials with the surface covered by hemostatic gauze or hemostatic drug. When primary or secondary hemorrhage occurs after the cutting operation of the tonsil, one end of the hemospheres of the clamping and oppressing hemostat stretches into the oral tonsillar pit to accurately oppress a bleeding point, the supporting mat is adhered to an appropriate part of cheek skin, an adjusting nut is rotated or the V-shaped arm is directly pressed, the clamping and oppressing force is adjusted, and the hemostat is appropriately fixed. The tonsil postoperation clamping and oppressing hemostat is convenient to use, small in trauma, light in pain and good in hemostatic effect.