16 results about "Common bile duct dilatation" patented technology

The invention relates to the technical field of ultrasonic examination, in particular to an ultrasonic lateral clinostatism examination bed beneficial for displaying a long axis of a common bile duct pancreatic segment, which comprises a support, wheels symmetrically arranged are rotatably mounted at the bottom of the support, and a fixing plate is fixed on the support; the first bed plate and the second bed plate are arranged on the fixing plate, and a supporting mechanism connected with the first bed plate and the second bed plate is arranged on the fixing plate; the lifting mechanism is arranged on the fixing plate and connected with the supporting mechanism; the nursing bed is characterized by further comprising an adjusting assembly which is arranged on the fixing plate and connected with the supporting mechanism, and the adjusting assembly can drive the first bed plate and the second bed plate to move through the supporting mechanism; the overturning assembly is arranged on the fixing plate and connected with the supporting mechanism; and the protective fences are symmetrically arranged on the fixing plate, and the fixing plate is further provided with a protective mechanism connected with the protective fences and the supporting mechanism.

This invention provides a single-operated duodenal sphincter cutter, comprising: an outer sheath, a guidewire, a metal wire, and a handle. The guidewire is inserted into the interior of the outer sheath through its wall and exits from its tip. The handle is connected to the tail of the outer sheath. One end of the metal wire is fixedly connected to the front of the outer sheath, and the other end is inserted into the interior of the outer sheath and connected to the handle. This invention features a dual-channel tube, with the guidewire entering the guidewire channel through the side wall. Its outer diameter is thinner than that of a conventional three-channel tube. The guidewire is led out through the side wall of the tube. With the outer sheath fixed in place, the operator can insert the guidewire into the common bile duct or pancreatic duct without the assistance of an assistant, increasing the success rate of cannulation.

[Problem] To provide: a cannula that can be easily inserted into a common bile duct or a pancreatic duct via a major duodenal papilla; and an endoscopic system provided with such a cannula. [Solution] A second camera 30 of a cannula 12 captures an image of the entrance of a common bile duct or a pancreatic duct in a state where the second camera 30 is inserted from the opening of a major duodenal papilla. A transparent shield 124 provides a cavity around the second camera 30 and ensures a field of view Vf of the second camera 30 in a state where the transparent shield 124 is inserted from the opening. The shield 124 has a convex surface 124c around the central axis CA of the field of view Vf of the second camera 30. The portion having the convex surface 124c has a uniform thickness. A guide wire 15 is configured to advance within the field of view Vf of the second camera 30.

The utility model relates to medical instrument technical field especially, and it is a kind of covered stent and implantation system.This covered stent includes support framework and film, wherein: support framework is the hollowed out cylinder structure of peripheral surface, it can be radially compressed and expand;Film is coated on part support framework, and drainage mesh is formed at the region of support framework not being coated by film.Due to film being coated on part support framework, drainage mesh is formed at the region of support framework not being coated by film, bile of gallbladder, bile in common hepatic duct and pancreatic juice in pancreatic duct can enter the inside of covered stent through drainage mesh and reach duodenal papilla, thereby avoiding the phenomenon that bile and pancreatic juice cannot flow out from common bile duct and reach duodenal papilla due to common bile duct being pressed by stent, and simultaneously, a plastic stent does not need to be additionally implanted in common bile duct to help common bile duct drainage, to achieve the purpose of reducing operation cost and operation complexity.

The utility model provides a multifunctional calculus extraction net basket, including net basket cap, outer sheath, net basket, connecting pipe and handle, net basket cap sets up at the head end outside of outer sheath, net basket and connecting pipe are placed in the inside of outer sheath, the head end of net basket is connected with the tail end of net basket cap, and the tail end is connected with the head end of connecting pipe, connecting pipe is inserted to the inside of outer sheath through the tail end of outer sheath, and the tail end of connecting pipe is connected with handle, and handle is located at the tail end outside of outer sheath, the utility model has multiple functions, can be directly placed into to common bile duct and carries out calculus extraction, also can be placed into to common bile duct, intrahepatic bile duct and gallbladder duct under the guidance of guide wire and carries out positioning calculus extraction, when the huge calculus is taken out, can be placed into the guide wire and carries out lithotripsy through the guide wire channel, and then the broken stone is taken out.

The invention discloses a bile duct millstone stent for ERCP. The bile duct millstone stent comprises a stent inner opening, anti-falling fins, a stent cylinder, stent millstone teeth, stent pore channels, stent outer fins and a stent outer opening. According to the bile duct millstone stent for ERCP, stone can be conveniently and automatically ground and discharged, after the stent bile duct is placed, under the combined action of duodenum physiologic peristalsis, bile flow and human body daily activities, the stent can generate micro-amplitude rotation and axial displacement, so that the stent millstone teeth can effectively scrape and grind common bile duct stone in contact with the stent cylinder, and the stent can be used for effectively removing the bile duct stone. The ground calculus can pass through a pore channel of the stent and is smoothly discharged into the duodenum under the flushing of bile which increases the flow rate and is generated due to the fact that the inner opening is large and the outer opening is small, the design is particularly suitable for emergency treatment of patients who suffer from bile duct calculus obstruction or cannot tolerate long-time ERCP operation, and through clinical use, the surgical instrument is convenient, rapid and flexible to use and operate, and has a wide application prospect. The problem of treatment of complex biliary calculi is effectively solved, and surgical operation safety is guaranteed.

This invention belongs to the field of biomedical technology, specifically relating to the application of spermine in the preparation of drugs for treating biliary atresia. This invention is the first to verify, through animal experiments (RRV mouse model), that spermine has a clear therapeutic effect on biliary atresia, achieving common bile duct recanalization and significantly reducing liver inflammation. Spermine itself possesses multiple functions including antioxidant, anti-inflammatory, and direct JAK1 inhibition, potentially working synergistically through multiple mechanisms such as mitigating initial damage and regulating immune responses, providing a more comprehensive pathological intervention than single-target inhibitors. Furthermore, spermine, as a known compound, has low production costs, and its application will greatly improve the accessibility of treatment.

The utility model provides a duodenum papilla dilatation balloon catheter with pressure measurement function, including outer sheath, combination and a plurality of branch pipes, the outer sheath includes drainage pipe section I, drainage pipe section II and drainage pipe section III connected in proper order from head to tail, the surface of drainage pipe section II is wrapped double -deck cylindrical dilatation film, double -deck cylindrical dilatation film includes inner layer film and outer layer film, and the outer layer film is equipped with opening, and the opening is equipped with pressure sensor, the combination is connected with the tail end of drainage pipe section III, and a plurality of branch pipes are connected with the combination, the utility model can be under the assistance of guide wire and carry out common bile duct or pancreatic duct intubation, can detect the pressure between balloon and duodenum papilla sphincter while dilating duodenum papilla sphincter, and the size of papilla dilatation is determined through pressure value, avoids the incidence of complications such as papilla sphincter laceration hemorrhage, bile leakage, intestinal bile reflux etc.

The invention relates to the field of gall bladder drainage stents, in particular to a gall bladder drainage plastic stent for ERCP surgery, which comprises a near-end pigtail section, a middle drainage section and a far-end drainage section which are integrally formed in sequence, the near-end pigtail section is used for remaining in a gall bladder, and friction elements are integrated on the outer side wall and the inner side wall of the near-end pigtail section; the middle drainage section is used for penetrating through a gall bladder tube and a common bile duct, the far-end drainage section is used for being reserved in the duodenum, an air bag reinforcing mechanism is arranged on the middle drainage section, preliminary anchoring is achieved through a pigtail ring structure of the near-end pigtail section, and meanwhile the air bag reinforcing mechanism of the middle drainage section is matched, so that the drainage effect is improved. The inflated annular air bag is tightly attached to the inner wall of the gall bladder tube, an anchoring and attaching dual-fixing mode is formed, external force caused by gastrointestinal peristalsis and bile flow is effectively resisted, the risks of stent displacement and slippage are remarkably reduced, and it is guaranteed that a drainage channel is continuous and smooth.

The utility model discloses an umbrella-shaped common bile duct calculus removal net basket, which relates to the technical field of calculus removal net baskets, and comprises a catheter, a connecting rod, a net basket, a net bag and a joint, one end of the connecting rod is positioned in the catheter, and the outer side of the connecting rod is fixedly connected with a sliding limiting component. The connecting rod is conveniently pushed by arranging the sliding limiting assembly, so that the mesh basket and the net bag matched connector are opened to form an umbrella shape, small stones can pass through a gap formed between the umbrella-shaped edge and the net and enter the net to be taken by the mesh basket, and the problems that due to the fact that metal wires of an existing stone taking mesh basket are prone to transverse displacement, the shapes are not fixed, and the stones are prone to slipping off are solved. Meanwhile, the problems that when the calculus removing balloon is full, the root of a nipple is prone to tearing and bleeding, a patient with common bile duct dilatation is difficult to remove calculus, small calculus is prone to being sucked into the bile duct when the balloon is cleaned, calculus removing fails, inconvenience is caused in the using process, and the using effect of the calculus removing net basket is reduced are solved.

The embodiment of the present application provides a rat bile duct catheter, which comprises a first catheter (1), a single knot (2) connected with the first catheter (1), a second catheter (3) connected with the single knot (2), a first double knot (4) connected with the second catheter (3), and a third catheter (5) connected with the first double knot (4). The first catheter (1) is inserted into the common bile duct and fixed through the single knot (2), the third catheter (5) is inserted into the duodenum and fixed through the first double knot (4), and the bile is taken at the second catheter (3). The first catheter is inserted into the common bile duct and fixed on the side of the common bile duct through the single knot, the third catheter is inserted into the duodenum and fixed on the side of the duodenum through the first double knot, and the second catheter is located outside the rat body, so that the bile can be taken at the second catheter. The present application conforms to the physiological structure of the rat, is not easy to fall off after being fixed, meets the requirement of long-term periodic collection of bile, and conforms to the requirement of animal welfare.

The utility model provides a duodenum papilla sphincter muscle incision knife with pressure measurement function, including outer sheath, guide wire, wire and handle, the outer sheath includes the drainage tube section I, drainage tube section II, drainage tube section III and drainage tube section IV connected in proper order from head to tail, the tail end of drainage tube section IV is connected with handle, the pipe wall of drainage tube section II is opened with the installation groove, is equipped with pressure sensor in the installation groove, one end of wire is connected with the pipe wall of outer sheath, and the other end inserts the inside of outer sheath and handle, guide wire inserts through handle, passes through drainage tube section IV, drainage tube section III, drainage tube section II, drainage tube section I in proper order, and is worn out. The utility model can be under the assistance of guide wire to carry out the common bile duct or pancreatic duct intubation, detects the pressure of common bile duct, pancreatic duct and duodenum papilla sphincter muscle while carrying out endoscopic under papilla sphincter muscle incision, determines the size of papilla sphincter muscle incision through pressure value, avoids that papilla sphincter muscle is too small or too big.

This invention relates to a novel use of synephrine in the preparation of drugs for treating cholestatic liver disease, belonging to the field of pharmaceutical technology. Cholestatic liver disease is characterized by jaundice and conjugated bilirubin and / or total bilirubin hyperconjugation caused by impaired bilirubin excretion due to various reasons. Its causes include common bile duct stones, pancreatic duct cancer, common bile duct malignant tumors, pancreatic cancer, biliary parasitic diseases, viral hepatitis cirrhosis, alcoholic liver disease, fatty liver disease, drug-induced liver injury, primary biliary cirrhosis, intrahepatic sclerosing cholangitis, and certain congenital diseases such as Dubin-Johnson syndrome and Rotor syndrome. This invention establishes a mouse cholestasis model using bile duct ligation and administers synephrine by gavage to evaluate its protective effect against liver injury. The results showed that synephrine significantly improved jaundice caused by cholestasis, reduced hepatocellular necrosis and inflammatory infiltration caused by cholestasis, alleviated bile duct dilation, decreased serum total bilirubin (TBIL) and direct bilirubin (DBIL), and reduced the levels of total bile acids (BA) in liver tissue and plasma. Furthermore, the above-mentioned effects of synephrine in improving cholestasis showed a clear dose-dependent effect. This invention reveals for the first time the application of synephrine in cholestatic liver disease, demonstrating good safety and promising clinical development prospects.

This invention discloses a gallbladder stone removal device, comprising a mesh-like stent made of one or more interwoven braided filaments and a stent delivery system. The mesh-like stent includes a stent body and distal and proximal stent ends located at its two ends. When the mesh-like stent is in the released state, the diameter of the distal stent end is greater than or equal to the diameter of the stent body, and the diameter of the proximal stent end is greater than or equal to the diameter of the stent body. After the distal stent end of this invention is released, the stent diameter is greater than the inner diameter of the cystic duct and the common bile duct, forming a funnel-shaped structure that completely conforms to the bile duct wall. Combined with an external negative pressure suction device, gallstones in the gallbladder can be drawn into this funnel-shaped structure in one go and finally removed from the biliary system, eliminating the need for multiple insertions and removals of the gallbladder using a stone retrieval basket, thus avoiding damage to the gallbladder and bile ducts. The stent made of biodegradable filaments completely degrades within three months in the biliary system, eliminating the need for secondary surgery and avoiding complications.

The utility model provides a kind of double guide wire nipple sphincter incision knife, comprising: outer sheath, handle, first guide wire, second guide wire and wire, first guide wire is inserted to the inside of outer sheath through the pipe wall of outer sheath, and it is worn from the pipe wall of outer sheath;Handle is connected with the tail end of outer sheath, second guide wire is inserted to the inside of outer sheath through handle, and it is worn from the head end of outer sheath;One end of wire is fixedly connected on the pipe wall of outer sheath, the other end is inserted into the inside of outer sheath, and is connected with handle.The utility model uses, assistant can implement guide wire auxiliary nipple sphincter incision knife cannula into pancreatic duct, on the basis of not increasing nipple incision knife pipe diameter, operator can operate second guide wire and insert into common bile duct through pipe wall lateral wall, realize double person multi-angle cannulation, increase the success rate of bile duct cannulation.

The invention relates to the technical field of medical information processing and clinical decision support, in particular to a multi-mode interpretable machine learning prediction method for predicting bile duct calculus discharge. According to the method, clinical data of twenty core predictive factors including four dimensions of demographic and clinical basis, iconography features, laboratory dynamics and time and intervention are obtained, a composite feature set is constructed through feature engineering, and a limit gradient is adopted to promote an ensemble learning model to predict the probability of spontaneous discharge of bile duct calculus. The contribution degree of each feature is quantified in combination with a Shapril additive interpretation method, and a feature importance ranking graph, a feature dependency graph and an individualized prediction interpretation report are generated; through innovative combination of multi-modal data fusion and an interpretable artificial intelligence technology, high-precision prediction and decision-making mechanism transparency are achieved, unnecessary endoscopic retrograde cholangiopancreatography can be effectively avoided through the high negative prediction value, and the method has obvious clinical application value.