Degradable radioactive biliary stent and method for producing the same

A technology of bile duct stent and manufacturing method, which is applied in the field of medical devices, can solve problems such as bile duct stent stenosis, achieve the effect of short irradiation distance, and inhibit bile duct intima hyperplasia and tumor growth

Active Publication Date: 2007-05-16
六安市济民医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The main technical problem to be solved by the present invention is to overcome the defects of the existing biliary stents and provide a degradable radioactive biliary stent with a new structure, which not only solves the restenosis problem of the ordinary NiTi alloy wire braided biliary stent

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] (1) Use NiTi alloy wire to braid the bile duct stent by hand or machine;

[0032] (2) Brush a layer of mixed solution of collagen+hydrochloric acid (acetic acid)+P-32, Pd-103 or I-125 on the surface of the bile duct stent manufactured above to form peritoneum, and then place it in a cross-linked Soaking under the agent;

[0033] (3) It can be prepared after freezing and drying;

[0034] (4) Sterilize with ethylene oxide gas before use.

Embodiment 2

[0036] (1) Use NiTi alloy wire to braid the bile duct stent by hand or machine;

[0037] (2) Brush a layer of gelatin+water+P-32, Pd-103 or I-125 on the surface of the bile duct stent manufactured above to form a peritoneum, and then soak it under a cross-linking agent;

[0038] (3) It can be prepared after freezing and drying;

[0039] (4) Sterilize with ethylene oxide gas before use.

Embodiment 3

[0041] (1) Use NiTi alloy wire to braid the bile duct stent by hand or machine;

[0042] (2) Brush the mixed solution of one layer of chitosan+acetic acid+P-32, Pd-103 or I-125 on the surface of the bile duct stent manufactured above to form the peritoneum, and then place it in a cross-linking agent Soak under;

[0043] (3) It can be prepared after freezing and drying;

[0044] (4) Sterilize with ethylene oxide gas before use.

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PUM

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Abstract

The invention relates to a radioactive bile duct support which can be degraded, used to treat cancer, wherein it is formed by the common bile duct support woven from NiTi alloy lines and the degradable belly film made from radioactive material covering the support. And its production comprises (1), using NiTi alloy lines to weave the bile duct support; (2), plating belly layer on the support, emerging it in crosslinker; (3), freezing and drying; (4), before using, using epoxyethane gas to disinfect it. The invention can treat and restrain the membrane increment and cancer growth, without hurting normal organism. And the epoxyethane, dope and chitose of carrier can be degraded.

Description

technical field [0001] The invention relates to a medical device, more specifically to a degradable radiated bile duct stent for treating tumors and a manufacturing method thereof. Background technique [0002] In 1985, Carrasco invented the first metal expansion stent for bile duct (AJR Am J Roentgenol. 1985; 145(6): 1279-1281), which achieved relatively good therapeutic effect. Our country also gradually introduced this technology in the 1990s. Common metal expansion stents are used in bile duct drainage with less trauma, and a larger-diameter stent can be implanted with a smaller-diameter delivery tube. The case fatality rate is low. After being placed in the narrowed bile duct, it can expand to the original diameter at human body temperature, and produce continuous expansion force on the narrow tube wall, so as to maintain the stability of ordinary metal expansion stents and not easily shift. [0003] The bile duct stent braided by ordinary NiTi alloy wire is a good met...

Claims

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Application Information

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IPC IPC(8): A61L31/14A61L31/16A61L31/10A61L31/02
Inventor 沈阳
Owner 六安市济民医药科技有限公司
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