33 results about "Biliary stents" patented technology

A tissue luminal stent is provided comprising a body having an elongated tubular configuration and a deployed configuration.SOLUTION: A tissue lumen stent includes a body having an elongated tubular configuration and a deployed configuration. When deployed, each of the first end and the opposite second end of the body expands into the first and second flange structures, leaving a generally cylindrical saddle region therebetween. At least one of the first and second flange structures has at least first and second inflection points defining first and second segments of the flange structure, wherein an angle of the first inflection point defined by the first segment and the cylindrical saddle region is at least as large as an angle of the second inflection point defined by the first segment and the second segment. The first segment includes a portion of increasing diameter and the second segment includes a portion of decreasing diameter.SELECTED DRAWING: Figure 10B

An example of a biodegradable biliary stent may comprise an elongated tubular member having a first end region, a second end region, and an intermediate region disposed therebetween, the elongated tubular member comprising at least one filament; and a biodegradable anchoring material that is coupled to and overlays a portion of the elongated tubular member, wherein the biodegradable anchoring material is coupled to and overlays at least to the first end region, the second end region, or both the first end region and the second end region.

The application provides application of a substance for detecting neutrophil and / or total bilirubin level in preparation of a kit for predicting early postoperative hemorrhage risk after endoscopic biliary stent implantation, and provides a related prediction model. The application firstly verifies that the substance for detecting neutrophil and / or total bilirubin level can be used for predicting early postoperative hemorrhage risk after endoscopic biliary stent implantation, and based on this, provides a related prediction model, the model has good discrimination ability, and can provide a valuable evaluation tool for preventing hemorrhage of a patient subjected to endoscopic biliary stent implantation.

The application relates to the field of metal nanopowder or plasma spraying, and particularly discloses a biliary stent prepared by combining metal nanopowder with a plasma spraying process. The ZrNbFeLa coating prepared by the plasma spraying process has good corrosion resistance, but the hemolysis rate is poor. Further, a proper amount of metal Ti is injected into the ZrNbFeLa coating, so that the biocompatibility of the ZrNbFeLa coating can be significantly improved, the corrosion resistance is not greatly affected, and the ZrNbFeLa coating can meet the use requirements of medical materials such as the biliary stent. It should be noted that the ion injection amount of the metal Ti needs to be controlled within 2.8*10 5 ions / cm 2 -1.2*10 12 ions / cm 2 , otherwise, too much titanium will cause the corrosion resistance of the ZrNbFeLa coating to sharply decrease.

The invention discloses a biliary stent for univariably regulating and controlling the dosage of an electron beam bactericide and a preparation method of the biliary stent, and belongs to the technical field of degradable biomedical materials and medical instruments. According to the stent, highly-oriented poly-L-lactic acid (PLLA) monofilaments serve as the unique raw material, and the self-expanding stent is woven after melt extrusion, solid-state thermal stretching and thermal setting; through univariate dose treatment of an electron beam sterilization (EBS) technology, the degradation rate and the degradation period can be precisely regulated and controlled in a gradient manner under the same process condition, and different clinical scenes such as gall bladder resection, biliary-intestinal anastomosis and biliary tract radiography can be matched respectively; the individual requirement of'etiological adaptation type 'is met, and a brand new normal form of single material, single variable and system one-way adjustment is provided for large-scale production and accurate application of the degradable biliary tract stent.

This invention relates to the field of medical device technology, and provides a biliary stent and its preparation method, comprising: a stent body, the stent body including a first structure and a second structure sequentially from one end to the other, the second structure including a channel body that maintains a spatial spiral in its natural state; the first structure including a first support ring and multiple first support wires; and a fixing structure, one end of the fixing structure being connected to the first support ring and / or multiple first support wires, and the other end being connected to the stent body, such that the multiple first support wires protrude outwards from the stent body, and the maximum diameter of the first structure is greater than the minimum diameter of the channel body; when the fixing structure loses its fixing function, the multiple first support wires are straight, and the average diameter of the first structure is smaller than the average diameter of the channel body. The biliary stent of this application solves the technical problems of stents in the prior art, such as easy displacement, easy breakage leading to large stent fragments, and difficulty in subsequent removal.

The utility model discloses a biliary stent and a delivery system. The biliary tract stent comprises an integrally-formed stent body, the stent body comprises a first stent tube body and a second stent tube body which are connected, and the outer diameter of the first stent tube body is set to be smaller than that of the second stent tube body. By the adoption of the biliary tract stent, the size of the first stent tube body can be matched with the size of a gallbladder tube, the size of the second stent tube body can be matched with the size of a common bile duct so that the biliary tract stent can be lowered, and the first stent tube body and the second stent tube body are integrally formed, so that in the process that the biliary tract stent is released through a conveying device, the biliary tract stent is not damaged. The biliary stent can be conveniently recycled at any time, so that the release position of the whole biliary stent can be conveniently adjusted, and the placement difficulty of the biliary stent can be reduced.

The present invention relates to a photocurable composition for manufacturing a patient-customized biliary stent by using a 3D printer, and a patient-customized biliary stent using same. A conventional photocurable composition for a 3D printer is hard and cannot be used as a biliary stent, but the photocurable composition for a 3D printer, of the present invention, can exhibit physical properties at levels enabling use as a biliary stent, and can be manufactured, using biocompatible material properties, as a stent customized for a patient requiring a biliary stent procedure.

The invention relates to the technical field of medical instruments, and provides a biliary tract stent and a preparation method thereof.The biliary tract stent comprises a stent body, the stent body sequentially comprises a first structure and a second structure from one end to the other end, and the second structure comprises a channel body keeping spatial spiral in the natural state; the first structure comprises a first supporting ring and a plurality of first supporting wires; one end of the fixing structure is connected with the first supporting ring and / or the first supporting wires, the other end of the fixing structure is connected with the support body, the first supporting wires protrude towards the outer side of the support body, and the maximum diameter of the first structure is larger than the minimum diameter of the channel body; when the fixing structure loses the fixing function, the first supporting wires are linear, and the average diameter of the first structure is smaller than that of the channel body. According to the biliary tract stent, the technical problems that in the prior art, a stent is prone to displacement and breakage to form large stent fragments and is difficult to discharge subsequently are solved.

The invention relates to the technical field of medical instruments, in particular to an ERCP novel bile duct stent and a preparation method thereof.The bile duct stent prepared through the preparation method has certain antibacterial ability by using an AMP-Chol12 peptide chain with the antibacterial ability, the bacterial membrane structure is destroyed through the electric charge effect, bacterial death is caused, and the bile duct stent has a certain antibacterial ability. Therefore, the bacterial infection risk is reduced. The physical antibacterial mechanism does not depend on chemical release, so that the antibacterial property is lasting, silver ions and antibiotics are not contained, bacterial drug resistance is not caused, meanwhile, good biocompatibility is achieved, the lubricating property can be improved, friction and damage are reduced, and bile sludge deposition is reduced.

An example of a biodegradable biliary stent may comprise an elongated tubular member having a first end region, a second end region, and an intermediate region disposed therebetween, the elongated tubular member comprising at least one filament; and a biodegradable anchoring material that is coupled to and overlays a portion of the elongated tubular member, wherein the biodegradable anchoring material is coupled to and overlays at least to the first end region, the second end region, or both the first end region and the second end region.

The anti-displacement bile duct support comprises a supporting rod, a drainage tube section I, a drainage tube section II and a drainage tube section III, the drainage tube section I, the drainage tube section II and the drainage tube section III are sequentially connected from head to tail, the two ends of the supporting rod are connected with the drainage tube section I and the drainage tube section III respectively, and the drainage tube section II and the supporting rod are arranged in parallel and have elasticity. The arc-shaped spring can be relatively bounced off; communicated channels are formed in the drainage tube section I, the drainage tube section II and the drainage tube section III and are used for placing guide wires. The bile duct stent is placed in a common bile duct through an endoscope to drain bile, the drainage tube section II and the supporting tube are bounced off in an arc shape, and displacement of the bile duct stent can be avoided; and no damage is caused to the bile duct wall and the nipple mucosa in the stent taking-out process.

This invention provides apparatus, methods, and kits that allow for simplified stent placement and retention in biological tubes other than blood vessels, particularly in antegrade biliary stent placement. The apparatus and methods advantageously allow for shorter imaging and stent placement times and significantly improve stent tolerance and / or retention in the tube. In a further advantageous aspect, the envisioned stent forms a complex fluid path to facilitate drainage of the tube. Furthermore, the apparatus and methods proposed herein reduce or even completely eliminate partial contraction of the peritoneal space during imaging and stent placement, and thus prevent operator exposure to exhaust gases carrying harmful agents.

Devices, methods, and kits are presented that allow for simplified stent placement and stent retention in a biological vessel other than a blood vessel, and especially biliary stent placement in an antegrade manner. The devices and methods advantageously allow for shortened imaging and stent placement time, and substantially improve tolerability and / or retention of the stent in the vessel, and in further beneficial aspects, contemplated stents form a composite fluid path to facilitate drainage of the vessel. Still further, the devices and methods presented herein reduce or even entirely eliminate partial deflation of the peritoneal space during imaging and stent placement and so prevent exposure of operating personnel to vented gases carrying harmful agents.

A biliary stent includes an expandable stent body that is expandable from a pre-deployment collapsed configuration to a post-deployment expanded configuration and a spun coating that is disposed over at least part of the expandable stent body. The spun coating includes a plurality of fibers defining interstices therebetween. The spun coating is adapted to impact tissue ingrowth. The spun coating may be adapted to encourage tissue ingrowth. The spun coating may be adapted to discourage tissue ingrowth.

The utility model relates to the technical field of biliary tract stents, and discloses an easily taken-out biliary tract stent which comprises a biliary tract supporting rod, bile drainage holes and wing plates, the bile drainage holes are evenly distributed outside the biliary tract supporting rod, the wing plates are assembled on the two sides of the outer portion of the biliary tract supporting rod, and flat supporting pipes are assembled on the two sides of the biliary tract supporting rod. Barbs are evenly distributed on the outer portion of the flat supporting tube, baffle rings are assembled on the two sides of the outer portion of the biliary tract supporting rod, and the baffle rings are annular shading rings and assembled on the outer portion of the biliary tract supporting rod. According to the biliary tract stent easy to take out, the situation that the whole biliary tract supporting rod slides in the body of a patient is avoided, meanwhile, the biliary tract supporting rod is conveniently driven by an external instrument through the flat supporting pipe designed in a flat mode, and the problem that a traditional cylindrical stent is prone to slipping when driven through a tool is solved; and therefore, under the condition of frequent driving, the slips in the body of a patient, and the pain of the patient is increased.

The present application relates to anastomosis stent technical field, especially to a kind of self-adapting response cholangioenteric anastomosis stent.It mainly aims at the problems that drug release cannot be accurately matched with disease course, valve is easily affected by environment to hinder drainage, single drug coating is difficult to meet multiple requirements and release is unstable in existing biliary tract stent, and the following technical scheme is proposed, including support framework, the support framework includes first support cylinder and second support cylinder, first support cylinder and second support cylinder are fixedly connected with connecting cylinder, and connecting cylinder is located inside first support cylinder and second support cylinder;Anti-inflammatory layer is sleeved on the outer circle of connecting cylinder, and the anti-inflammatory layer is located between first support cylinder and second support cylinder.The present application can realize accurate drug release, guarantee normal bile drainage, meet multiple clinical requirements and release stably, so as to improve treatment effect, reduce postoperative complication risk and promote patient recovery.

The invention discloses a biliary stent and a preparation method thereof, and relates to the technical field of medical instruments. The biliary stent is of a concentric tubular structure and comprises a fastest degradation inner layer, a sub-fast degradation middle layer and a slowest degradation outer layer from inside to outside, and a plurality of supporting pieces are arranged between the layers. The used materials are all degradable materials with high safety and excellent biocompatibility. The provided biliary stent is a novel biliary stent which can be degraded in a gradient mode and is excellent in biocompatibility. The degradation process can be actively managed, the resilience force of the bile duct wall can be effectively resisted in the degradation period, continuous and reliable bile drainage is provided for bile flow, and the blocking risk is effectively avoided; finally, all degradation products are safely absorbed by the body, no foreign matter is left, secondary operation for taking out is not needed, patient pain and medical cost are reduced, and the method is expected to be vigorously popularized.

The present disclosure provides an endoprosthesis where a preferably polymeric coating has a number of surface features such as protrusions or textures that are arranged in a micropattern. The endoprosthesis optionally has an expanded state and a contracted state, and in some cases includes a stent with a polymeric coating attached to an outer surface of the stent. The stent may have an inner surface defining a lumen, an outer surface, and a stent thickness defined between the inner surface and outer surface. The stent may comprise a plurality of surface textures extending from the stent surfaces, wherein the textures are arranged in a macropattern.

Devices, systems, and methods for deploying biliary stents. The biliary stent is provided with leaflets and pleats to expand between a retracted position and an expanded position. The stent is loaded in a retracted position on a shaft of the delivery device, delivered to the bile duct. When the shaft retracts through the stent, flaps on the shaft apply an outward force to the stent, causing the stent to enter a larger expanded position. In the expansion position, the folds form a drainage channel so as to reduce blockage of the stent in the use period.

Apparatus (20) is provided for use with a guidewire (12). The apparatus includes a guide tube (22) having a guidewire-engaging portion (122) and a slit (28) extending proximally along a wall of the guide tube, from a distal end (32) of the tube, a proximal end (29) of the slit being located distally to a proximal end (30) of the tube. A first stent (52) surrounds the tube and is advanceable together with the tube into a lumen of a subject, the first stent being slidably advanceable off the distal end of the tube; and a second stent (54), proximal to the first stent, surrounding a proximal portion of the tube, and advanceable off the distal end of the tube into the lumen, and placed alongside the first stent subsequently to advancement of the first stent off the distal end of the tube. Other applications are also described.

The utility model discloses a biliary stent with a covering film. The biliary tract stent comprises an integrally-formed stent body and a covering film covering the stent body, the stent body comprises a first stent tube body and a second stent tube body which are connected, and the outer diameter of the first stent tube body is set to be smaller than that of the second stent tube body; wherein a channel for interstitial fluid to pass through is formed in a connecting area of the first stent tube body and the second stent tube body. By the adoption of the biliary tract stent, the size of the first stent tube body can be matched with the size of a gallbladder tube, the size of the second stent tube body can be matched with the size of a common bile duct so that the biliary tract stent can be lowered, and the first stent tube body and the second stent tube body are integrally formed, so that in the process that the biliary tract stent is released through a conveying device, the biliary tract stent is not damaged. The biliary stent can be conveniently recycled at any time, so that the release position of the whole biliary stent can be conveniently adjusted, and the placement difficulty of the biliary stent can be reduced.

The utility model belongs to the technical field of biliary tract stents, and particularly relates to an internal and external drainage biliary tract stent which comprises a connector and further comprises a compression cavity fixedly installed on one side of the connector, a threaded groove is fixedly formed in the inner wall of the compression cavity, a compression rod is installed on one side of the threaded groove in a penetrating mode, and the threaded groove is arranged through the compression cavity. Then the compression cavity is movably connected with the compression rod conveniently through the threaded groove, then the compression cavity and the air bag are conveniently connected through the air pipe, then when an operation starts, the stent is placed in an operation opening, and when the stent reaches a designated position, air in the compression cavity is reduced by screwing the compression rod, so that the air bag is inflated; the drainage tube is simple in structure and convenient to use, the inflation size of the air bag can be controlled, so that ectopic and falling of the drainage tube are avoided, the problem of intestinal juice backflow is solved, diseases such as cholangitis and septicopyemia of a patient caused by intestinal juice backflow are avoided, the safety of an operation is improved, and postoperative rehabilitation is accelerated.

The invention discloses a magnetic biliary tract stent pushing system which comprises a magnetic biliary tract stent composed of a stent body, a connecting part and a magnetic tail end. The pushing system is composed of an electromagnet, a lead wire, a switch assembly and a power plug; the electromagnet is connected with the magnetic tail end in an inserted mode. The invention provides a magnetic biliary stent pushing system. The instrument is based on magnetic field force, and simple, convenient and reliable release is realized by utilizing the switching characteristic of the electromagnet; and on the other hand, the positioning characteristic of the magnetic field force is utilized to ensure safe and simple recovery of the bracket. In addition, due to the fact that releasing and recycling are easy, convenient and safe, the influence of the length of the support on the treatment effect is reduced, and the adaptability of the device is improved; and meanwhile, the blunt design of the tail end of the bracket improves the application safety.

A biliary tract stent particle loading device relates to the technical field of auxiliary equipment for biliary tract stents and is characterized in that a moving mechanism is mounted in a sliding groove, clamping mechanisms are mounted on frame walls on two sides of the moving mechanism respectively, a filling mechanism is mounted on a main frame, a pressing end of the filling mechanism corresponds to a clamping end of each clamping mechanism, and a clamping end of the filling mechanism corresponds to a clamping end of each clamping mechanism. A power switch group is mounted on the main body frame, and the input end of the power switch group is connected with the output end of an external power supply; according to the biliary tract stent particle loading device, the biliary tract drainage tube needing to be provided with radioactive particles is clamped through the clamping mechanism, the notch, where the radioactive particles are installed, of the biliary tract drainage tube is adjusted, clamping does not need to be conducted again, operation is convenient for medical staff, and the working efficiency is improved. The clamping mechanism provided with the biliary tract drainage tube is driven by the moving mechanism to move, and radioactive particles are mounted in the biliary tract drainage tube through the filling mechanism, so that a worker can operate conveniently.

A biliary tract stent for inhibiting scar and endothelial proliferation comprises a left segment and a right segment, characterized in that: an intermediate segment is arranged between the left segment and the right segment, the left segment, the right segment and the intermediate segment are all mesh structures, the intermediate segment is a retracted type, so that the overall structure of the biliary tract stent is slightly smaller in the middle and larger at both ends; the intermediate segment is provided with a treatment layer, which is used to inhibit scar and endothelial proliferation; the technical scheme of the application adopts the synergistic effect of radiotherapy and mechanical support to accurately inhibit fibroblast proliferation at the stenosis site of the biliary tract anastomotic mouth, inhibit scar and reduce endothelial proliferation, solves the problem of repeated restenosis after traditional stent implantation, and greatly prolongs the patency time of the stent.

This invention relates to a biliary stent material, its preparation method, and its application, belonging to the field of biliary stent technology. A method for preparing a biliary stent material includes the following steps: dissolving 4-(ethylene glycol ketal)-ε-caprolactone and caprolactone copolymer in an organic solvent, then adding barium sulfate to obtain a mixed solution; after the organic solvent in the mixed solution evaporates, a composite casting membrane is obtained; the composite casting membrane is coated onto the surface of a mold, heated, cooled, and the mold is removed to obtain a tubular stent; the tubular stent is immersed in a dopamine hydrochloride buffer solution and stirred to obtain a tubular stent loaded with a polydopamine coating; curcumin is added to an amnion decellularized hydrogel solution to obtain a composite hydrogel solution; the tubular stent loaded with the polydopamine coating is then immersed in the composite hydrogel solution and allowed to gel statically to obtain the biliary stent material. The biliary stent material of this invention has the characteristics of being biodegradable, having good flexibility, and excellent biocompatibility.

The invention provides an antibacterial and anti-inflammatory bile duct stent, and belongs to the technical field of biological materials, the antibacterial and anti-inflammatory bile duct stent comprises a stent body, the stent body comprises a plurality of wave-shaped rings arranged in a first direction and a connecting piece connected with a supporting piece, and the plurality of wave-shaped rings form a drainage channel; a functional coating is arranged on the stent body, and the functional coating comprises a ternary complex formed by self-assembly of metal ions, polyphenol compounds and quaternary ammonium salt compounds. According to the bile duct stent, the narrow biliary tract can be effectively expanded, normal flow of bile is recovered, smoothness of the biliary duct is kept, and the multiple synergistic effects of resisting tumor development, resisting bacterial infection and resisting inflammation can be achieved.

A biliary stent includes an expandable stent body that is expandable from a pre-deployment collapsed configuration to a post-deployment expanded configuration and a spun coating that is disposed over at least part of the expandable stent body. The spun coating includes a plurality of fibers defining interstices therebetween. The spun coating is adapted to impact tissue ingrowth. The spun coating may be adapted to encourage tissue ingrowth. The spun coating may be adapted to discourage tissue ingrowth.

The application discloses a kind of supermolecular antibacterial material of construction by oxazine functional group composition, preparation method and application, belong to polymer material field.The antibacterial material is composed of supermolecular antibacterial agent, polymer resin material, compatible agent, antioxidant, lubricant, is formed by high temperature mixing, obtains various purposes antibacterial material and product, this antibacterial material has excellent bacteriostatic effect to escherichia coli and staphylococcus aureus, so that material has long-term antibacterial property, simultaneously still has higher strength, is applicable to biliary tract stent etc. human implant medical material, with wide application prospect.