63 results about "Biliary stents" patented technology

The invention discloses a biliary tract stent capable of being accurately released, which comprises a stent far end, a stent straight section and a stent near end which are connected in sequence, the number of layers of the stent is at least one, and the stent far end and the stent near end are made of materials with different colors. The number of layers of the stent is one, the materials of the stent far end, the stent straight section and the stent near end of the stent comprise but are not limited to silicone rubber, polyurethane, polyethylene, nylon or modified nylon Pebax, and the material hardness of the stent far end, the stent straight section and the stent near end of the stent ranges from Shore 25D to Shore 72D. Compared with a traditional stent of the same specification, the biliary tract stent capable of being accurately released has the advantages that the cross sectional area of an inner cavity is larger by 40%-100%, meanwhile, the inner surface of the stent is made of the super-smooth material, a biological membrane and bile mud are not prone to being attached, and the smooth time of the biliary tract stent is greatly prolonged.

The utility model provides a self-discharging type double-helix biliary stent, and belongs to the technical field of medical drainage catheters. Comprising a stent body, and the stent body comprises a connecting pipe, a first spiral pipe and a second spiral pipe; the connecting pipe is used for fixedly connecting the first spiral pipe and the second spiral pipe; the first spiral tube is mounted on one side of the connecting tube and used for draining bile; the second spiral pipe is installed on the side, away from the first spiral pipe, of the connecting pipe. Compared with an existing double-pigtail stent or a self-discharging type biliary tract spiral stent, the spiral structure of the two sets of spiral tubes can better adapt to the physiological form of the biliary tract, stable fixation is formed, the risk that an original stent with one end being of a vertical structure possibly pierces the intestinal wall is avoided, and the intestinal tract can be more stably fixed. Due to the arrangement of the self-discharging double-helix biliary stent, convenience is provided for taking out the stent subsequently.

This application relates to the technical field of medical devices and discloses a plastic biliary stent, comprising a stent body, a delivery unit, and a guidewire. The stent body comprises a main tube, a first wing, and a second wing. The first wing is disposed at the distal end of the main tube, and the second wing is disposed at the proximal end of the main tube. The ends of the first and second wing adjacent to each other can be unfolded relative to the main tube. The delivery unit comprises a sheath tube and an inner tube. The inner tube moves within the sheath tube, and the distal end of the inner tube includes a cutting head. The guidewire is sequentially passed through the main tube and the inner tube. The first wing is received in the main tube via a connecting line. The distal end of the sheath tube is sheathed over the main tube and receives the second wing. The distal end of the inner tube extends into the proximal end of the main tube, and the inner tube has a limiting mechanism for abutting the main tube to limit the main tube. This application can prevent the stent from scratching tissue during delivery.

A guide tube (220) has a guidewire-engaging portion (222) at a distal portion (260) thereof, a first stent (54) surrounding the guide tube, advanceable together with the guide tube into a subject's lumen, a guidewire (12) arranged (i) entering the guide tube from a distal-end (320) opening thereof, (ii) disposed in the guidewire-engaging portion, and (iii) passing out of the guide tube proximally to the guidewire-engaging portion, and a second stent (54), proximal to the first stent, surrounding a proximal portion (240) of the guide tube and the guidewire. The first stent is slidably deployable off the distal end of the guide tube upon the guidewire having laterally exited the guidewire-engaging portion, and the second stent is slidably deployable off the distal end of the guide tube subsequently to deployment of the first stent, without the guidewire having been moved proximally. Other applications are also described.

The invention discloses a biliary tract stent with a positioning structure for hepatobiliary pancreatic surgery, relates to the technical field of biliary tract stents.The biliary tract stent is suitable for treating biliary tract stenosis or obstruction, and comprises a tubular stent body and the positioning structure, the positioning structure comprises a Y-shaped anchoring protrusion and a developing mark, the Y-shaped anchoring protrusion is arranged on the outer wall of the stent, and the developing mark is arranged on the outer wall of the stent. Both the cross section and the vertical section are Y-shaped, the embedding force with the inner wall of the biliary tract is remarkably enhanced, the postoperative displacement risk is reduced, the developing mark adopts iodine-doped polylactic acid or gold rings and tantalum particles, X-ray and ultrasonic bimodal developing is supported, the intraoperative positioning accuracy is improved, the stent body and the anchoring protrusions can be made of degradable materials, the degradation performance is excellent, and the stent is suitable for popularization and application. The stent is suitable for short-term implantation, does not need to be taken out through a secondary operation and is good in biocompatibility, the surface of the stent can be coated with a hydrophilic or antibacterial coating, and inflammation and infection risks are reduced. The manufacturing process adopts extrusion molding, laser cutting, injection molding, hot pressing or mechanical embedding, the process is simplified, the efficiency is high, and the method is suitable for micro bracket production.

A tissue luminal stent is provided comprising a body having an elongated tubular configuration and a deployed configuration.SOLUTION: A tissue lumen stent includes a body having an elongated tubular configuration and a deployed configuration. When deployed, each of the first end and the opposite second end of the body expands into the first and second flange structures, leaving a generally cylindrical saddle region therebetween. At least one of the first and second flange structures has at least first and second inflection points defining first and second segments of the flange structure, wherein an angle of the first inflection point defined by the first segment and the cylindrical saddle region is at least as large as an angle of the second inflection point defined by the first segment and the second segment. The first segment includes a portion of increasing diameter and the second segment includes a portion of decreasing diameter.SELECTED DRAWING: Figure 10B

An example of a biodegradable biliary stent may comprise an elongated tubular member having a first end region, a second end region, and an intermediate region disposed therebetween, the elongated tubular member comprising at least one filament; and a biodegradable anchoring material that is coupled to and overlays a portion of the elongated tubular member, wherein the biodegradable anchoring material is coupled to and overlays at least to the first end region, the second end region, or both the first end region and the second end region.

The application provides application of a substance for detecting neutrophil and / or total bilirubin level in preparation of a kit for predicting early postoperative hemorrhage risk after endoscopic biliary stent implantation, and provides a related prediction model. The application firstly verifies that the substance for detecting neutrophil and / or total bilirubin level can be used for predicting early postoperative hemorrhage risk after endoscopic biliary stent implantation, and based on this, provides a related prediction model, the model has good discrimination ability, and can provide a valuable evaluation tool for preventing hemorrhage of a patient subjected to endoscopic biliary stent implantation.

The application relates to the field of metal nanopowder or plasma spraying, and particularly discloses a biliary stent prepared by combining metal nanopowder with a plasma spraying process. The ZrNbFeLa coating prepared by the plasma spraying process has good corrosion resistance, but the hemolysis rate is poor. Further, a proper amount of metal Ti is injected into the ZrNbFeLa coating, so that the biocompatibility of the ZrNbFeLa coating can be significantly improved, the corrosion resistance is not greatly affected, and the ZrNbFeLa coating can meet the use requirements of medical materials such as the biliary stent. It should be noted that the ion injection amount of the metal Ti needs to be controlled within 2.8*10 5 ions / cm 2 -1.2*10 12 ions / cm 2 , otherwise, too much titanium will cause the corrosion resistance of the ZrNbFeLa coating to sharply decrease.

The invention provides a novel anti-reflux integrated biliary tract stent for bile flow monitoring, which comprises a biliary tract stent in the shape of a woven mesh cylinder, and a flexible covering film is arranged in the biliary tract stent. A flow sensor unit for monitoring the flow and the flow velocity of bile in the biliary tract of a patient in real time and an anti-reflux assembly are mounted in the flexible covering film; wherein the anti-reflux assembly comprises an anti-reflux membrane flap, a plurality of through holes are formed in the anti-reflux membrane flap, and a plurality of anti-reflux flexible parts are arranged in the through holes; the biliary tract bile flow monitoring system has the advantages that a flow sensor in the flow sensor unit can monitor the flow and the flow speed of bile in the biliary tract of a patient in real time, the flow sensor can transmit collected information to an in-vitro terminal device through a Bluetooth module, and therefore the bile flow related characteristics can be monitored in real time; and bile in the biliary tract is prevented from entering the biliary tract stent and flowing back into the biliary tract through the anti-reflux flap and the anti-reflux flexible piece.

The invention discloses a biliary stent for univariably regulating and controlling the dosage of an electron beam bactericide and a preparation method of the biliary stent, and belongs to the technical field of degradable biomedical materials and medical instruments. According to the stent, highly-oriented poly-L-lactic acid (PLLA) monofilaments serve as the unique raw material, and the self-expanding stent is woven after melt extrusion, solid-state thermal stretching and thermal setting; through univariate dose treatment of an electron beam sterilization (EBS) technology, the degradation rate and the degradation period can be precisely regulated and controlled in a gradient manner under the same process condition, and different clinical scenes such as gall bladder resection, biliary-intestinal anastomosis and biliary tract radiography can be matched respectively; the individual requirement of'etiological adaptation type 'is met, and a brand new normal form of single material, single variable and system one-way adjustment is provided for large-scale production and accurate application of the degradable biliary tract stent.

This invention relates to the field of medical device technology, and provides a biliary stent and its preparation method, comprising: a stent body, the stent body including a first structure and a second structure sequentially from one end to the other, the second structure including a channel body that maintains a spatial spiral in its natural state; the first structure including a first support ring and multiple first support wires; and a fixing structure, one end of the fixing structure being connected to the first support ring and / or multiple first support wires, and the other end being connected to the stent body, such that the multiple first support wires protrude outwards from the stent body, and the maximum diameter of the first structure is greater than the minimum diameter of the channel body; when the fixing structure loses its fixing function, the multiple first support wires are straight, and the average diameter of the first structure is smaller than the average diameter of the channel body. The biliary stent of this application solves the technical problems of stents in the prior art, such as easy displacement, easy breakage leading to large stent fragments, and difficulty in subsequent removal.

The utility model discloses a biliary stent and a delivery system. The biliary tract stent comprises an integrally-formed stent body, the stent body comprises a first stent tube body and a second stent tube body which are connected, and the outer diameter of the first stent tube body is set to be smaller than that of the second stent tube body. By the adoption of the biliary tract stent, the size of the first stent tube body can be matched with the size of a gallbladder tube, the size of the second stent tube body can be matched with the size of a common bile duct so that the biliary tract stent can be lowered, and the first stent tube body and the second stent tube body are integrally formed, so that in the process that the biliary tract stent is released through a conveying device, the biliary tract stent is not damaged. The biliary stent can be conveniently recycled at any time, so that the release position of the whole biliary stent can be conveniently adjusted, and the placement difficulty of the biliary stent can be reduced.

The present invention relates to a photocurable composition for manufacturing a patient-customized biliary stent by using a 3D printer, and a patient-customized biliary stent using same. A conventional photocurable composition for a 3D printer is hard and cannot be used as a biliary stent, but the photocurable composition for a 3D printer, of the present invention, can exhibit physical properties at levels enabling use as a biliary stent, and can be manufactured, using biocompatible material properties, as a stent customized for a patient requiring a biliary stent procedure.

The invention discloses a disposable biliary tract stent and a pressure detection system, the disposable biliary tract stent comprises a pushing catheter, the outer side of the pushing catheter is sleeved with an auxiliary hose, the outer side of the auxiliary hose is movably connected with a biliary tract branch tube, and the top of the biliary tract branch tube is symmetrically provided with two notches. According to the biliary tract pressure detection device, the pressure on the outer side of the detection wire is detected, the real-time pressure extending into the biliary tract is detected, the detection stability is guaranteed, the guide wire is additionally arranged, the positions of the pushing catheter and the auxiliary hose are fixed, the pushing catheter and the auxiliary hose are detached during separation, and the biliary tract pressure threshold setting module is additionally arranged, so that the detection accuracy is improved. The pressure threshold value recorded in the biliary tract in real time is set, threshold value detection is conducted on the pressure stretching into the biliary tract through the set pressure threshold value, the safety of the pressure in the biliary tract is guaranteed, and danger during detection is avoided.

A tissue lumen stent is provided with a body having an elongated tubular configuration and a foreshortened configuration. In the foreshortened configuration, downstream and upstream ends of the body expand radially into downstream and upstream flange structures, leaving a generally cylindrical saddle region therebetween. In some embodiments, the flange structures are non-symmetrical with respect to one another. Systems and methods of using the stents are also disclosed.

The invention relates to the technical field of medical instruments, and provides a biliary tract stent and a preparation method thereof.The biliary tract stent comprises a stent body, the stent body sequentially comprises a first structure and a second structure from one end to the other end, and the second structure comprises a channel body keeping spatial spiral in the natural state; the first structure comprises a first supporting ring and a plurality of first supporting wires; one end of the fixing structure is connected with the first supporting ring and / or the first supporting wires, the other end of the fixing structure is connected with the support body, the first supporting wires protrude towards the outer side of the support body, and the maximum diameter of the first structure is larger than the minimum diameter of the channel body; when the fixing structure loses the fixing function, the first supporting wires are linear, and the average diameter of the first structure is smaller than that of the channel body. According to the biliary tract stent, the technical problems that in the prior art, a stent is prone to displacement and breakage to form large stent fragments and is difficult to discharge subsequently are solved.

The invention relates to the technical field of medical instruments, in particular to an ERCP novel bile duct stent and a preparation method thereof.The bile duct stent prepared through the preparation method has certain antibacterial ability by using an AMP-Chol12 peptide chain with the antibacterial ability, the bacterial membrane structure is destroyed through the electric charge effect, bacterial death is caused, and the bile duct stent has a certain antibacterial ability. Therefore, the bacterial infection risk is reduced. The physical antibacterial mechanism does not depend on chemical release, so that the antibacterial property is lasting, silver ions and antibiotics are not contained, bacterial drug resistance is not caused, meanwhile, good biocompatibility is achieved, the lubricating property can be improved, friction and damage are reduced, and bile sludge deposition is reduced.

An example of a biodegradable biliary stent may comprise an elongated tubular member having a first end region, a second end region, and an intermediate region disposed therebetween, the elongated tubular member comprising at least one filament; and a biodegradable anchoring material that is coupled to and overlays a portion of the elongated tubular member, wherein the biodegradable anchoring material is coupled to and overlays at least to the first end region, the second end region, or both the first end region and the second end region.

A catheter (220) having: a guidewire engagement portion (222) at a distal portion (260) thereof; a first stent (54) surrounding the catheter, the first stent being capable of being advanced together with the catheter into a lumen of a subject; a guidewire (12) arranged to (i) enter the catheter from a distal end (320) opening of the catheter, (ii) be disposed in the guidewire engagement portion, and (iii) exit the catheter proximal to the guidewire engagement portion; and a second stent (54) proximal to the first stent, the second stent surrounding the proximal portion (240) of the catheter and the guidewire. The first stent is capable of being slidably deployed from the distal end of the catheter when the guidewire has laterally exited the guidewire engagement portion, and the second stent is capable of being slidably deployed from the distal end of the catheter after deployment of the first stent without moving the guidewire proximally. Other applications are also described.

The present invention relates to a medical device (100) for use as a ureteral stent, a biliary stent or a urinary catheter in a human or animal body. The medical device (100) comprises a hollow device body (101) having at least one body lumen (102), an inner body surface (105) and an outer body surface (106), wherein the inner body surface (105) delimits the at least one body lumen (102). The medical device (100) further comprises at least one array (110) of microstructures (111) located on the inner body surface (105) and / or the outer body surface (106) and configured to locally increase fluid-induced shear stress acting on the device body (101) in use of the medical device (100) in response to applying an acoustic field to the medical device (100). The invention further relates to a medical system comprising such as a medical device and an activation device configured to be positioned externally of a human or animal body, wherein the activation device comprises at least one sound transducer configured to generate an acoustic field for application from externally of the human or animal body to the medical device. The invention further relates to as to a method of acoustically activating such a medical device during use in a human or animal body, in particular for cleaning purposes and / or mass transport.

The anti-displacement bile duct support comprises a supporting rod, a drainage tube section I, a drainage tube section II and a drainage tube section III, the drainage tube section I, the drainage tube section II and the drainage tube section III are sequentially connected from head to tail, the two ends of the supporting rod are connected with the drainage tube section I and the drainage tube section III respectively, and the drainage tube section II and the supporting rod are arranged in parallel and have elasticity. The arc-shaped spring can be relatively bounced off; communicated channels are formed in the drainage tube section I, the drainage tube section II and the drainage tube section III and are used for placing guide wires. The bile duct stent is placed in a common bile duct through an endoscope to drain bile, the drainage tube section II and the supporting tube are bounced off in an arc shape, and displacement of the bile duct stent can be avoided; and no damage is caused to the bile duct wall and the nipple mucosa in the stent taking-out process.

This invention provides apparatus, methods, and kits that allow for simplified stent placement and retention in biological tubes other than blood vessels, particularly in antegrade biliary stent placement. The apparatus and methods advantageously allow for shorter imaging and stent placement times and significantly improve stent tolerance and / or retention in the tube. In a further advantageous aspect, the envisioned stent forms a complex fluid path to facilitate drainage of the tube. Furthermore, the apparatus and methods proposed herein reduce or even completely eliminate partial contraction of the peritoneal space during imaging and stent placement, and thus prevent operator exposure to exhaust gases carrying harmful agents.

Devices, methods, and kits are presented that allow for simplified stent placement and stent retention in a biological vessel other than a blood vessel, and especially biliary stent placement in an antegrade manner. The devices and methods advantageously allow for shortened imaging and stent placement time, and substantially improve tolerability and / or retention of the stent in the vessel, and in further beneficial aspects, contemplated stents form a composite fluid path to facilitate drainage of the vessel. Still further, the devices and methods presented herein reduce or even entirely eliminate partial deflation of the peritoneal space during imaging and stent placement and so prevent exposure of operating personnel to vented gases carrying harmful agents.

A biliary stent includes an expandable stent body that is expandable from a pre-deployment collapsed configuration to a post-deployment expanded configuration and a spun coating that is disposed over at least part of the expandable stent body. The spun coating includes a plurality of fibers defining interstices therebetween. The spun coating is adapted to impact tissue ingrowth. The spun coating may be adapted to encourage tissue ingrowth. The spun coating may be adapted to discourage tissue ingrowth.

The utility model relates to the technical field of biliary tract stents, and discloses an easily taken-out biliary tract stent which comprises a biliary tract supporting rod, bile drainage holes and wing plates, the bile drainage holes are evenly distributed outside the biliary tract supporting rod, the wing plates are assembled on the two sides of the outer portion of the biliary tract supporting rod, and flat supporting pipes are assembled on the two sides of the biliary tract supporting rod. Barbs are evenly distributed on the outer portion of the flat supporting tube, baffle rings are assembled on the two sides of the outer portion of the biliary tract supporting rod, and the baffle rings are annular shading rings and assembled on the outer portion of the biliary tract supporting rod. According to the biliary tract stent easy to take out, the situation that the whole biliary tract supporting rod slides in the body of a patient is avoided, meanwhile, the biliary tract supporting rod is conveniently driven by an external instrument through the flat supporting pipe designed in a flat mode, and the problem that a traditional cylindrical stent is prone to slipping when driven through a tool is solved; and therefore, under the condition of frequent driving, the slips in the body of a patient, and the pain of the patient is increased.

The present application relates to anastomosis stent technical field, especially to a kind of self-adapting response cholangioenteric anastomosis stent.It mainly aims at the problems that drug release cannot be accurately matched with disease course, valve is easily affected by environment to hinder drainage, single drug coating is difficult to meet multiple requirements and release is unstable in existing biliary tract stent, and the following technical scheme is proposed, including support framework, the support framework includes first support cylinder and second support cylinder, first support cylinder and second support cylinder are fixedly connected with connecting cylinder, and connecting cylinder is located inside first support cylinder and second support cylinder;Anti-inflammatory layer is sleeved on the outer circle of connecting cylinder, and the anti-inflammatory layer is located between first support cylinder and second support cylinder.The present application can realize accurate drug release, guarantee normal bile drainage, meet multiple clinical requirements and release stably, so as to improve treatment effect, reduce postoperative complication risk and promote patient recovery.

The invention provides a biliary tract stent automatic monitoring system based on wireless transmission, which comprises a sensor module, a data preprocessing unit and a doctor terminal module which are arranged on a biliary tract stent, the data preprocessing unit comprises a calling system terminal module arranged beside a sickbed of a patient or a microprocessor module installed on a biliary tract support. The sensor module is used for collecting parameter information in the biliary tract of a patient and packaging the parameter information into a data packet according to a preset protocol, and then the data packet is sent to the calling system terminal module or the microprocessor module through the Bluetooth module. Compared with the prior art, the novel biliary tract stent has the advantages that the novel biliary tract stent capable of measuring related data in the biliary tract is combined, an innovative patient nursing process after the hepatobiliary surgery is constructed, traditional manual monitoring is replaced with an automatic process, the data measured by the biliary tract stent is fed back to a doctor in time, the doctor can conduct clinical diagnosis in time, and the patient nursing efficiency is improved. And giving corresponding treatment.

The invention discloses a biliary stent and a preparation method thereof, and relates to the technical field of medical instruments. The biliary stent is of a concentric tubular structure and comprises a fastest degradation inner layer, a sub-fast degradation middle layer and a slowest degradation outer layer from inside to outside, and a plurality of supporting pieces are arranged between the layers. The used materials are all degradable materials with high safety and excellent biocompatibility. The provided biliary stent is a novel biliary stent which can be degraded in a gradient mode and is excellent in biocompatibility. The degradation process can be actively managed, the resilience force of the bile duct wall can be effectively resisted in the degradation period, continuous and reliable bile drainage is provided for bile flow, and the blocking risk is effectively avoided; finally, all degradation products are safely absorbed by the body, no foreign matter is left, secondary operation for taking out is not needed, patient pain and medical cost are reduced, and the method is expected to be vigorously popularized.

The present disclosure provides an endoprosthesis where a preferably polymeric coating has a number of surface features such as protrusions or textures that are arranged in a micropattern. The endoprosthesis optionally has an expanded state and a contracted state, and in some cases includes a stent with a polymeric coating attached to an outer surface of the stent. The stent may have an inner surface defining a lumen, an outer surface, and a stent thickness defined between the inner surface and outer surface. The stent may comprise a plurality of surface textures extending from the stent surfaces, wherein the textures are arranged in a macropattern.