380results about How to "Play a sustained release role" patented technology

The invention discloses a preparing method of injectable sodium hyaluronate gel containing microballoons. The preparing method comprises the following steps of dissolving sodium hyaluronate into purewater to obtain a solution A; adding a microballoon material into the solution A, and conducting uniform stirring to obtain a homodisperse suspension liquid B; adjusting the PH value of the suspensionliquid B to obtain a suspension liquid C; adding a crosslinking agent into the suspension liquid C, conducting uniform stirring to obtain a homodisperse suspension liquid D, after a reaction is carried out for a certain period of time, crosslinking sodium hyaluronate in the suspension liquid D to form colloid E containing the homodisperse microballoon material; smashing the colloid E to obtain gel particles F, and obtaining gel particles G through screens with different mesh numbers; removing soluble impurities and crosslinking agents in the gel particles G in a repeated soaking or dialytic mode to obtain gel particles H; utilizing a PBS buffering solution for balancing for repeatedly soaking the gel particles H to obtain gel particles I; obtaining the sodium hyaluronate gel through the procedures of semi-dehydration, filling and sterilization. By means of the preparing method, the problem that the microballoon material is deposited and gets caked is effectively solved.

The invention relates to a bee product composition, comprising the following raw material by weight part: honey 20-50 parts, royal jelly 10-20 parts, pollen 20-35 parts, propolis powder 5-10 parts, bee larvae and pupae power 5-10 parts. The propolis powder is added into the honey to fully stir up in 60-70 degree water bath and then the royal jelly freeze-dry power, the pollen, the bee larvae and pupae power are added into the mixture in turn and the mixture is fully stirred and uniformly mixed. The bee product composite can fully develop their actions of the effective constituents of various bee products and the effective constituents are fully absorbed by the human and the taste is improved and the bee product composition is convenient for being taken and stored without any side effects.

The invention relates to a soil conditioner and preparation and application methods thereof. The soil conditioner is prepared from the following ingredients in percentage by weight: 30% to 35% of overrotten organic fertilizer, 35% to 40% of fruit tree branch charcoal, 14.5% to 19.5% of oyster shell powder, 8% of pyroligneous liquor, 6.0% of natural humus acid, and 1.5% of titanium oxide. The conditioner has effects of loosening soil, improving soil acidification and removing soil hardening, and has effects of improving water and nutrient retention capacity of soil, supplementing trace elements in soil calcium and magnesium and reducing crop diseases and pests. The soil conditioner can replace slaked lime, an organic fertilizer and the like as the soil conditioner to be applied to the planting industry.

The invention belongs to the field of building material additives and particularly relates to a high-slump-retaining polycarboxylic acid composite water reducer and a preparation method thereof. The polycarboxylic acid composite water reducer is prepared from, by weight, 100 parts of unsaturated polyoxyethylene ether macromonomer, 0.5-2 parts of oxidizing agent, 0.1-0.4 part of reducing agent, 0.4-0.8 part of chain transfer agent and 10-15 parts of comonomer. The preparation process of the high-slump-retaining polycarboxylic acid composite water reducer is easy and convenient to operate and environmentally friendly, and saves energy. The high-slump-retaining polycarboxylic acid composite water reducer is prepared from, by weight, 45-55% of polycarboxylic acid water reducer, 10-15% of modified attapulgite, 2-4% of retarder, 0.03-0.08% of defoamer, 0.01-0.05% of air entraining agent, 5-8% of absolute ethyl alcohol, 4-7% of modified hydrotalcite and the balance water. The high-slump-retaining polycarboxylic acid composite water reducer is good in adaptability and has excellent dispersion, slump retaining and slow release performance.

The invention discloses a preparation method of a long-acting anti-microbial textile. The preparation method concretely comprises the following processes: firstly a desizing or refining process is carried out for the textile, and pretreatment is carried out for the textile by using low temperature plasma; textile which is pretreated is dipped at a room temperature for 10-30 minutes in a mixed finishing solution which comprises a chitosan solution and a silver nitrate solution, the textile is taken out and superfluous finishing solution is rolled out, liquor retention is 100-150%, the textile which is dipped in the finishing solution is transferred into a piece of microwave equipment for carrying out treatment for a certain period of time, after the reaction ends, the textile is taken out and washed with water, and after drying, the anti-microbial textile is obtained. The anti-microbial textile has the advantages of excellent anti-microbial properties, washing resistance, lasting anti-microbial effects, simple preparation technology, and low chemical pollution; the method overcomes the problems of complex processes, bad stability of nanometer silver, bad anti-microbial durability and the like existed in the prior art.

The invention relates to a waterborne acrylic macromolecular compound and salts thereof, as well as preparation methods and applications thereof. The method comprises the following steps of: dissolving hydrophilic acrylic monomers containing amino, acrylic monomers containing hydroxyl, acrylic monomers containing quaternary ammonium salts and acrylic monomers containing carboxyl in water, then adding a water-soluble azo compound as an initiator, and dropwise adding the monomer hybrid solution containing the initiator to water or alcohol-water solution for copolymerization reaction. Stain-proof paints prepared by using metal salts of the waterborne acrylic macromolecular compound can effectively prevent adhesion of fouling organism in seawater, and have the advantage of being environment-friendly.

The invention discloses a wheat dedicated composite coated fertilizer which is characterized by being prepared from the following raw materials in parts by weight: 34-40 parts of a castor cake, 18-25 parts of a rapeseed cake, 22-25 parts of wheat bran, 10-13 parts of a fishbone powder, 6-8 parts of clay, 100-110 parts of dry cow dung, 24-30 parts of bagasse, 1-2 parts of polyglutamic acid, 2-3 parts of urea formaldehyde, 35-40 parts of urea, 33-40 parts of ammonium phosphate, 18-24 parts of potassium chloride, 2-3 parts of ferrous sulfate, 6-8 parts of an EM agent, 8-10 parts of a soil improvement agent, and a proper amount of water. The fertilizer is reasonable in formula, more comprehensive and balanced in nutrition, and good in use effect; coating can play the sustained release role, and the fertilizer efficiency is allowed to be slowly released; moreover, with addition of polyglutamic acid, water and fertilizer retention abilities are improved, soil organic matters are increased, the fertilizer efficiency utilization rate can be significantly improved, the wheat yield and quality are greatly improved, and thus economic benefits of winter wheat are improved.

The invention discloses a method for encapsulated osteoblasts to support and regulate the in-vitro amplification of cord blood hematopoieticstem/progenitorcells (He) in the hypoxia condition, belonging to the fields of biotechnology and tissue TSPCS engineering. The method is characterized in that the human osteoblasts are embedded by gelatin-alginate-chitosan (GAC) microcapsule as matrix feeder cells and co-cultured with the cord blood HSPCs in the 5% hypoxia environment to obtain the HSPCs. The invention adopts GAC microcapsule to separate the human osteoblasts from the cord blood HSPCs to avoid the cell contamination and immunological rejection. Furthermore, the pore passages of the microcapsule are capable of causing hemopoietic growth factors secreted by the osteoblasts in the microcapsule to expand to the habitat of the HSPCs and play a role of stimulating the amplification of the hematopoietic stem/progenitor cells. Moreover, the material of the microcapsule has the slow release function to the expansion of the growth factors to increase the concentration gradient of the growth factors on the surface of the microcapsule, which is helpful for the long-term function of the growth factor. In addition, the microencapsulated osteoblasts form the 3D environment, which not only causes the culture system to contain more osteoblasts, but also causes the culture system to have bigger HSPCs-OBs action area compared with the co-culture pattern of the osteoblasts cultured by adherence. Besides, in the 5% hypoxia environment, the co-culture system is capable of better simulating the hematopoietic microenvironment iche of human bone marrow the osteoblasts have significant effects on the characteristic maintenance and number amplification of stem cells of the HSPCs.

The invention discloses a preparation method for efficient anti-bacterial composite hemostatic sponge. The preparation method comprises the following steps: S1, adding sodium chloride and phosphonium salt into a sodium alginate solution to obtain a solution A; S2, adding an emulsifier into dispersion liquid to obtain a solution B, and preparing a 4 to 6 percent calcium chloride solution to serve as a solution C; S3, adding the solution A into the solution B in a water-oil ratio of 1 to (3-7) by an emulsion-crosslinking method, stirring to form an emulsion, adding the solution C into the emulsion for reacting, curing, centrifuging, washing and drying to obtain porous alginate drug-carrying microspheres; S4, dissolving chitosan hydrochloride into water to obtain an aqueous solution, adding the porous alginate drug-carrying microspheres prepared in the step S2 and a hemostatic medicament, performing freeze drying repeatedly, washing and sterilizing to obtain the hemostatic sponge. The hemostatic sponge has high water absorptivity, can rapidly stop bleeding, plug wounds, inhibit wound infection and effectively promote healing of the wounds; the thrombus risk is avoided.

The invention discloses a pollution-free paddy rice planting method. The method comprises the following steps: A, planting milk vetch as green manure in a rice field, and applying a basic manure, wherein 500-800 kg of the basic manure is applied to each mu of the rice field; B, after the rice field is subjected to exposure, performing rotary tillage, ridge separation, irrigation and rice transplanting; C, applying a compound fertilizer to seedlings after the seedlings are inserted; D, grazing 8-15 7-10-day-old ducks to each mu of the rice field after 15-20 days of rice transplanting, evicting the ducks from the rice field after 25-40 days, spraying a biological pesticide, draining for 7-10 days, topdressing 30-100 kg of the compound fertilizer used in the step C to each mu of the rice field, irrigating till the depth of water is 8-10 cm, grazing 5-10 7-10-day-old ducks to each mu of the rice field again, and evicting the ducks from the rice field before 15-20 days of rice mature. According to the pollution-free paddy rice planting method, the yield is high, pollution is avoided, produced rice tastes good, and meanwhile, high-quality duck is obtained.

The invention discloses an etching solution for high-transmittance anti-dazzle glass, and a preparation method thereof. Raw materials of the etching solution comprise hydrofluoric acid, ammonium fluoride, ammonium bifluoride, magnesium fluoride, aluminum fluoride, calcium fluoride, calcium hydrogen fluoride, potassium hydrogen fluoride, ammonium chloride, zinc chloride, sodium acetate, barium sulfate, sodium fluoroborate, ammonium fluoroborate, sodium phosphate, ammonium biphosphate, potassium phosphate, ethylene diamine tetraacetic acid, nitrilotriacetic acid, a viscosity regulator, a surfactant, a sulfuric acid solution and water. The preparation method of the etching solution for high-transmittance anti-dazzle glass has the advantages of mild process and mild conditions, and the etching solution for high-transmittance anti-dazzle glass, prepared through the method, has the advantages of good stability, high transmittance and atomization rate, and good anti-dazzle effect.

The present invention discloses an endogastric flotation slow-released administration system, including medicine-loaded shell body and medicine-loaded kernel body, in which said kernel body is placed in the interior of said shell body, in the interior of said kernel body the air is held, and the specific weight of said endogastric flotation show-released medicine is less than 1g/cm. Said invention also provides the method for preparing endogastric flotation slow-released administration system by utilizing three-dimensional printing forming technique.

The invention relate to phosphoric acid based etching liquid with high etching selectivity and a method for preparing the phosphoric acid based etching liquid. The phosphoric acid based etching liquidwith the high etching selectivity mainly comprises, by weight, 50-90% of phosphoric acid, 0.005-1% of silicon-containing compounds, 0.005-1% of fluorine-containing compounds, 0.005-1% of fluorine stabilizers, 0.005-5% of surfactants and the balance water. The phosphoric acid based etching liquid and the method have the advantages that components and the types of novel additives and novel stabilizers are used, accordingly, SiO2 layer etching of the phosphoric acid based etching liquid can be obviously reduced, the Si3N4 layer etching speeds of the phosphoric acid based etching liquid can be obviously increased, and the Si3N4/SiO2 etching selectivity can be obviously improved.

The invention discloses a preparation method of probiotic solid-state fermented complete feed. The preparation method is characterized in that lactobacilli, pichia pastoris and bacillus subtilis cultured by a culture medium are mixed with neutral proteinase and water according to a ratio; the mixture in a fog form is sprayed into complete feed according to a certain ratio; and in vacuum, the complete feed with the mixture is subjected to solid state fermentation at a temperature of 30 to 35 DEG C for 3 to 7 days so that the probiotic solid-state fermented complete feed as a product is obtained. The probiotic solid-state fermented complete feed can be directly used for animal feeding without drying. The probiotic solid-state fermented complete feed has the advantages that antibiotics are not adopted; a large amount of live probiotics are used; anti-nutritional factors of crude proteins are destroyed; a large amount of macromolecular nutrients are degraded; product digestibility is high; a feed conversion rate is greatly reduced; and a nitrogen output volume of excrement and urine is reduced.

A saline-alkali soil deep-improving method by chemical-biological technology includes steps of S1, improving chemical components of the saline-alkali soil by chemical measures, firstly, adding humic acid fertilizer into the saline-alkali soil, then adding chemically acidic fertilizer into the saline-alkali soil, applying physiologic acidic fertilizer, and finally adding mineral chemical fertilizer into the saline-alkali soil; S2, improving the saline-alkali soil by biological measures, firstly, planting suaeda salsa of euhalophyte on the saline-alkali soil to be treated, or planting scutellaria strigillosa hemsl when salt content of the saline-alkali soil ranges from 0.2% to 0.3%. The saline-alkali soil deep-improving method provides a feasible, economic and efficient scheme for improving the saline-alkali soil in coastal regions, improvement time is short, effect is good and no backflow is caused after improvement.

The invention discloses a planting method for organic high-yield rice. The method comprises: planting broad beans in a rice field, after harvesting the broad beans, performing green manure dressing and retting, and applying base fertilizer; performing water-controlling harden-seedling on rice seedlings whose seedling age is 15-20 days for 2-3 days; performing rotary tillage, ridge dividing, irrigation on the rice field, and then transplanting rice seedlings; after the rice seedlings survive, dressing a compound fertilizer to promote rice seedling tiller; 13-18 days after rice transplanting, putting newly-hatched ducklings whose day-age is 12-20 in the rice field according to amount of 8-15 per mu, 25-40 days after putting the ducks in the rice field, driving the ducks out of the rice field, spraying biopesticide, performing field draining for 7-10 days, topdressing a nitrogen-phosphorus-potassium composite fertilizer according to amount of 20-50 kg per mu, and then irrigating to 8-10 cm, and driving the ducks in the rice field, 15-20 days before the rice is mature, taking back the ducks, and cutting off water and drying the field. The planting method for organic high-yield rice is high in yield, and obtained rice is good in quality, and high-quality duck meat is obtained.

The invention discloses a pet food for inhibiting appetite, which comprises dog chews such as leather picker bones or leather rolling bones and the like which are made of animal skin such as cow skin, pig skin and/or sheep skin and the like or the compound of animal skins, and is characterized in that the animal skin or the grains of the animal skin is puffed and then coated, wrapped or blended with galactolipid and/or microencapsulated galactolipid. The dog chews can inhibit the appetite of pets, avoid excessive eating and is beneficial to the health of pets.

The invention relates to the technical field of daily chemical products and particularly relates to essential oil nanoparticles and a preparation method thereof as well as application of the essential oil nanoparticles to preparation of a mosquito-repelling product. Plant essential oil is used as a mosquito-repelling agent, and all the plant essential oils have synergistic interaction and mutual promotion effects, so that the mosquito-repelling effect is good. Each type of the essential oil is covered with mesoporous silicon dioxide, so that the essential oil can be more stable and has a slow releasing effect. The nanoparticles are added into the mosquito-repelling product so that the adding amount of the essential oil in mosquito-repelling emulsion is reduced and the acting time also is prolonged. According to the mosquito-repelling emulsion provided by the invention, the essential oil, vegetable oil and purslane herb extract can also have anti-allergy and anti-inflammation, and itch-reliving and swelling-eliminating effects, and the irritation on skins is reduced, so that the mosquito-repelling emulsion has better safety and more efficient mosquito-repelling effect. An experiment shows that under a proper proportion, the effective mosquito-repelling time of the mosquito-repelling emulsion provided by the invention can reach 14.1h; and after 18h, the effective repelling rate can still reach 87.3%.

The invention relates to a liquid fertilizing and water-retaining mulching film and a preparation method thereof and belongs to the technical field of agricultural production. The liquid mulching film comprises components in percentage by mass as follows: 1%-10% of a modified macromolecular composite polymer and 90%-99% of a fertilizing agent; the modified macromolecular composite polymer comprises components in parts by weight as follows: 35-45 parts of ultra-fine silica sol, 5-10 parts of zinc oxide, 40-100 parts of carboxymethylcellulose or hydroxypropyl methyl cellulose, 20-30 parts of N-isopropylacrylamide, 0.02-0.3 parts of a cross-linking agent and 0.4-1.2 parts of an initiator; the solid content of the ultra-fine silica sol is in a range of 10-30wt%, and particle sizes of silica in the ultra-fine silica sol are in a range of 1-100 nm. The prepared liquid mulching film can significantly increase the water-retention rate of soil and improve physical and chemical properties of the soil, can be completely degraded, is free of pollution and can substitute for plastic mulching films on a large scale.

The invention relates to a nano heterogeneous Fenton catalyst with an alginate core coated with copper/magnetic Fe3O4 and a preparation method of the Nano heterogeneous Fenton catalyst. The invention relates to a heterogeneous Fenton catalyst and a preparation method thereof, which aims at solving the technical problems of the existing homogenous Fenton catalyst that the requirement on pH is high, and the catalyst ions are difficult to separate and likely to lose. The catalyst is formed by adopting sodium alginate as a core and coating the core with Fe3O4 nano particles and spherical particles of copper chloride. The preparation method comprises the following steps: I, adding a precipitant into a ferrous salt and ferric salt solution, washing precipitates, and then dispersing the precipitates to obtain a magnetic nano Fe3O4 dispersed solution; II, adding a sodium alginate solution into the dispersed solution, and uniformly mixing to prepare suspension slurry; and III, dropwise adding the suspension slurry into a copper chloride solution, carrying out the stationary reaction, separating, and drying to obtain the nano heterogeneous Fenton catalyst with the alginate core coated with the copper/magnetic Fe3O4. The nano heterogeneous Fenton catalyst can be applied to the water treatment.

The invention discloses a Newcastle disease-H9 subtype avian influenza bivalent dual-adjuvant inactivated vaccine and a preparation method thereof. The bivalent vaccine consists of a concentrated and inactivated ND and AI (H9) venom, levamisole hydrochloride and an oil adjuvant, wherein every milliliter of inactivated vaccine contains 0.5-16 mg of levamisole hydrochloride immunopotentiator. When the synergic ND-AI (H9) bivalent dual-adjuvant inactivated vaccine prepared with the method is applied to immunized chicken, the humoral immunity and cell immune levels of table poultry and laying hens can be raised effectively, the growth is promoted, and rate of live weight growth is increased. The bivalent dual-adjuvant inactivated vaccine has an immune effect which is remarkably superior to that of the conventional chicken ND-AI bivalent oil emulsion inactivated vaccine, and can be used for effectively protecting chicken flocks from being intruded by the ND virus and AI (H9) virus and preventing the Newcastle disease and H9 subtype avian influenza at the immune period.

The invention discloses a composition containing a dihydropyridine calcium channel blocker and a preparation method thereof and relates to a sustained-release preparation of felodipine, which comprises felodipine which is dihydropyridine calcium channel blocker and function as an active ingredient, enalapril which is angiotensin converting enzyme inhibitor, as well as a slow release material, a filling agent and a lubricating agent which function as auxiliary materials; wherein the slow release material contains hydroxypropyl methylcellulose. As the enalapril which is angiotensin converting enzyme inhibitor is added in coating solution, the curative effect of the sustained-release preparation is improved.

The present invention provides a polyolefin anti-fogging film master batch and a preparation method thereof. The polyolefin anti-fogging film master batch comprises, by weight of EVA, (1) 100% of EVA, (2) 0.5-2.5% of modified diatomite, (3) 3-7% of an anti-fogging agent, and (4) 1-3% of an EVA-g-BA graft. According to the present invention, after diatomite in the master batch is subjected to surface modification through a polyol amine compound, occurrence of particle agglomeration can be hindered so as to easily disperse diatomite in the anti-fogging agent and significantly enhance an absorption effect of diatomite on the dripping agent; with the EVA-g-BA graft, uniform dispersion of the polyol fatty acid ester anti-fogging agent in the polyethylene greenhouse film resin is promoted, wettability of the film surface is significantly improved, and the utilization rate of the dripping agent is significantly increased, such that the anti-fogging lasting period of the polyethylene greenhouse film can be prolonged to more than 65 months from about 3-10 months, damage of fog drops on the polyethylene greenhouse film at the middle-later stage of use is solved, and good market application prospects are provided.

The invention discloses c construction method of imitate pseudo with low digestive property and belong to the technical field of food, belongs to the technical field of foods and is characterized in that starch is used as a raw material to construct slow-digesting dietary fiber and starch dietary fiber simulation of structures, and a promotive functional food for people's health with obesity and diabetics is developed herein. The construction method is simple, the materials are easy to obtain, using complex chemical modification to change the characteristics of starch, such as low digesting speed, is not required; animal experiments show that the prepared products can reduce the weight of a fat animal significantly, and can lower post-dining glucose slow release.

The invention relates to a method for preparing drug carrier or gene carrier support, wherein said method comprises (1), support surface pretreatment that splashing or plating gold, fixing macromolecule; (2), solidifying the drug or gene molecule on the surface of support that activating the support surface, loading carrier, sealing and solidifying the drug or gene. The invention uses laminated installment, connects mesh macromolecule skeleton on the support, to improve the drug carrier, reduce the toxicity of support and connecting molecule and the immunogen. The invention uses mesh molecule to connect carbohydrate, peptide, and antibody, to connect the drug and antibody firmly and release drug slowly. The invention uses mesh molecule static adsorption gene molecule and transfer medium molecule to improve the transfer efficiency of gene molecule.