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Development type degradable repair biliary tract stent

A technology of biliary tract and contrast agent, which is applied in the field of degradable biliary tract stent for developing, can solve the problems of inability to understand the shape and position of implanted materials, the patient's tissue is vulnerable, and low electron density, and achieves controllable and reduced degradation time. Effects of scar formation and promotion of healing and repair

Pending Publication Date: 2016-09-21
青岛蓝博云健康产业发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Most of these materials only contain elements with low electron density and low specific gravity, such as C, H, and O, and cannot be detected by X-rays, which makes it impossible for medical personnel to understand the specific shape and position of implanted materials in the body, and cannot place them accurately. At the lesion site, the patient's tissue is also vulnerable to injury, which brings difficulties to the operation. Therefore, the development-type degradable biliary tract repair stent is a current research hotspot. The contrast agents mainly include barium and iodine. Barium is mainly used for esophagus and gastrointestinal contrast, while iodine is mainly used for contrast of bile duct and gallbladder, renal pelvis and urinary tract, arteries and veins

Method used

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  • Development type degradable repair biliary tract stent

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Effect test

Embodiment 1

[0057] Extrusion threaded pipe: Extrusion complete set of equipment includes extruder, traction device, sizing device, cooling device and supporting equipment. Extrusion temperature: 150°C. The extrusion material is a biodegradable material: polylactic acid-polyglycolic acid copolymer (PLGA). The pitch of the thread groove is: 10mm.

[0058] Cooling: cooling by air cooling.

[0059] Guaiac coating: through automatic dispensing machine and other equipment, the glue solution is applied to the spiral groove on the outer wall of the threaded tube. The healing and repairing functional material is a colloid solution made of polysaccharide.

[0060] The preparation method of the healing and repairing functional material is as follows: weigh 50g of chitosan powder, put it into a glass reaction vessel, add 130mL of propionic anhydride solution of acylating reagent, add 120ml of ethanol, stir evenly, control the reaction temperature at 35°C, add ethanesulfonic acid solution 1.0ml was...

Embodiment 2

[0069] Extrusion threaded pipe: Extrusion complete set of equipment includes extruder, traction device, sizing device, cooling device and supporting equipment. Extrusion temperature: 150°C. The extrusion material is a biodegradable material: polylactic acid-polyglycolic acid copolymer (PLGA). The pitch of the thread groove is: 10mm.

[0070] Cooling: cooling by air cooling.

[0071] Guaiac coating: through automatic dispensing machine and other equipment, the glue solution is applied to the spiral groove on the outer wall of the threaded tube. The healing and repairing functional material is a colloid solution made of polysaccharide.

[0072] The preparation method of the healing and repairing functional material is as follows: weigh 50g of chitosan powder, put it into a glass reaction vessel, add 130mL of propionic anhydride solution of acylating reagent, add 120ml of ethanol, stir evenly, control the reaction temperature at 35°C, add ethanesulfonic acid solution 1.0ml was...

Embodiment 3

[0081] Extrusion threaded pipe: Extrusion complete set of equipment includes extruder, traction device, sizing device, cooling device and supporting equipment. Extrusion temperature: 150°C. The extrusion material is a biodegradable material: polylactic acid-polyglycolic acid copolymer (PLGA). The pitch of the thread groove is: 10mm.

[0082] Cooling: cooling by air cooling.

[0083] Guaiac coating: through automatic dispensing machine and other equipment, the glue solution is applied to the spiral groove on the outer wall of the threaded tube. The healing and repairing functional material is a colloid solution made of polysaccharide.

[0084] The preparation method of the healing and repairing functional material is as follows: weigh 50g of chitosan powder, put it into a glass reaction vessel, add 130mL of propionic anhydride solution of acylating reagent, add 120ml of ethanol, stir evenly, control the reaction temperature at 35°C, add ethanesulfonic acid solution 1.0ml was...

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Abstract

The invention relates to a development type degradable repair biliary tract stent. The development type degradable repair biliary tract stent comprises, by weight, 50-100 parts of degradable medical materials A, 0.1-50 parts of healing repair materials B, 0.001-0.05 part of developers C, 0.001-0.05 part of anti-biliary tract-tumor medicines and / or anti-gallstone medicines D and 0.001-0.05 part of vitamins. The development type degradable repair biliary tract stent has the advantages that the development type degradable repair biliary tract stent is excellent in biocompatibility and stable and controllable in degradation time, and the morphology and the locations of implant materials can be quickly judged; decompression support and drainage effects can be realized in complicated biliary tract reconstruction procedures, and the development type degradable repair biliary tract stent is favorable for biliary tract healing repair, and can bring convenience for observing bile conditions, postoperative cholangiography effects and the like.

Description

technical field [0001] The invention belongs to the field of biomedical materials, and relates to a developing type degradable repairing biliary tract stent. Background technique [0002] Interventional radiology is a new branch of the field of radiology, and many of its techniques are derived from surgery, adopted and improved by radiologists. [0003] Interventional therapy comes from interventional radiology. It is an emerging treatment method between surgery and internal medicine. It uses X-ray perspective, CT positioning, B-type ultrasound equipment and other medical imaging equipment as guidance to guide special catheters or instruments through human arteries, The veins, the natural ducts of the digestive system, the biliary tract or the drainage ducts after surgery reach the diseased area in the body to obtain tissue cells, bacteria or biochemical data, and can also perform imaging data to obtain imaging data, so as to achieve the purpose of diagnosing the disease. V...

Claims

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Application Information

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IPC IPC(8): A61L31/14A61L31/16A61L31/06A61L31/04
CPCA61L31/042A61L31/06A61L31/14A61L31/148A61L31/16A61L2300/21A61L2300/216A61L2300/416A61L2300/428C08L67/04C08L69/00C08L5/08
Inventor 潘学理全志伟
Owner 青岛蓝博云健康产业发展有限公司
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