Blood vessel plugging device for coronary perforation and application

A technology for blocking device and coronary artery, which is applied in the field of biomedicine to achieve the effect of shortening operation time

Inactive Publication Date: 2015-05-06
李国庆
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Aiming at the current research status of the occlusion device that effectively solves the vascular perforation caused by PCI operation at home and abroad, and the occlusion effect is good, the occlusion material is safe, the structure of the occlusion device is simple, and the occlusion device is convenient for clinical operation, the present invention provides A vascular occlusion system device for coronary artery perforation, which aims to provide a vascular occlusion system device for the treatment of vascular perforation caused by PCI operation and its application. The vascular occlusion system device has excellent occlusion effect and is suitable for various The shape of the vascular perforation caused by the PCI operation, and during the clinical operation, the occlusion components in the vascular occlusion system device will not fall off in the blood vessel, thereby causing complications for the patient

Method used

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  • Blood vessel plugging device for coronary perforation and application
  • Blood vessel plugging device for coronary perforation and application
  • Blood vessel plugging device for coronary perforation and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] Embodiment 1: Suitable for vascular occlusion device in coronary perforation

[0057] See attached figure 1 to attach Figure 9 , the present invention is applicable to the blood vessel occlusion device in coronary perforation, which is specifically described as follows:

[0058] The blood vessel occlusion device suitable for coronary perforation includes an injection pressurization component, a coronary perforation occlusion advancement component and a coronary perforation occlusion component. The injection booster component consists of a syringe (16), a pressure gauge (15), a rubber tube ( 13) composition; the coronary artery perforation occlusion propulsion assembly consists of a flexible alloy guide wire (1), a balloon (5), a jacket tube (6), a guide wire (7), a guide sleeve (8), a socket (9) ), a retaining sleeve (10), and an injection connection sleeve (11); the coronary perforation occlusion assembly is mainly composed of occlusion modules (2) and occlusion ...

Embodiment 2

[0076] Embodiment two: the preparation of gelatin

[0077] The preparation of gelatin: take a 1000mL conical flask, put 5g type A gelatin ( Gelatins , type A ) into 500mL double-distilled water, and heated at 50°C with magnetic stirring. Cool to room temperature after the gelatin is completely dissolved. Adjust the pH of the aqueous gelatin solution to 12 with 10M NaOH solution, and stir at room temperature for 30 minutes. Accurately weigh 0.33g of succinic anhydride, slowly add in batches to the gelatin solution, and adjust the pH to keep it at 12 while adding. Continue to react at room temperature for 24h. Check the pH value every 3 hours during this period. If the pH value drops below 12, adjust it with 10M NaOH solution to restore it to strong alkaline conditions. After the reaction is completed, use a clean dialysis bag (MW=7000-14000) for dialysis for 2 days, and change the water 4 times a day. lyophilized.

Embodiment 3

[0078] Example 3: Preparation of olive-shaped plugging module (2)

[0079] Take 16g of prepared gelatin, slowly add it into 100mL double-distilled water in batches, stir magnetically at room temperature while adding, and prepare a 16% gelatin solution after completely dissolving, stir evenly, pour it into an olive-shaped mold, and place it in a constant temperature oven at 60°C After cross-linking for 1 hour, take it out, dialyze it with double distilled water for 2 days, change the water 4 times a day, and dry it at room temperature overnight, which is the prepared olive-shaped plugging module (2).

[0080] The size of the blocking module (2): the maximum extension length of the blocking module (2) is determined by, and a guide wire hole diameter is provided at the center of each blocking module (2) to adapt to the PTCA guide wire.

[0081] The preparation process of different occlusion modules (2) is basically the same, only the prepared gelatin material needs to be inject...

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Abstract

The invention discloses a blood vessel plugging device for coronary perforation and an application. The blood vessel plugging device comprises an injection pressurizing component, a coronary perforation plugging pushing component and a coronary perforation plugging component, wherein the coronary perforation plugging pushing component is composed of a flexible alloy guide wire, a balloon, a jacked pipe, a guide wire, a guide sleeve, a socket, a keeping sleeve and an injected liquid connecting sleeve; the coronary perforation plugging component is composed of a plugging module and a plugging cap which are in different shapes; the plugging module is hinged to one end of the plugging cap; the plugging cap is composed of a plugging cap overturning raised spherical surface and a plugging cap concave spherical surface; a guide wire hole is formed in the middle of the plugging module; the plugging cap is arranged on the outer side of the guide wire hole; the plugging cap can only be opened toward the outer side; the plugging cap in the plugging module can be automatically plugged under the effect of blood direction and pressure; the perforation of blood vessels in different shapes and sizes can be met; the perforation hole of a blood vessel can be completely plugged; the risk in blood exosmosis is reduced; the postoperative complications can be reduced; the application value is higher.

Description

technical field [0001] The present invention relates to the technical field of biomedicine, in particular, the present invention relates to the technical field of a blood vessel occlusion device for coronary artery perforation and its application. Background technique [0002] coronary heart disease ( Coronary artery disease, CHD) referred to as coronary heart disease, is the most common heart disease. Coronary heart disease is caused by atherosclerosis in the coronary arteries. This atherosclerotic plaque accumulates on the coronary intima, and over time, the coronary lumen is severely narrowed or even blocked, resulting in reduced blood flow, insufficient oxygen supply, and reduced nutritional supply to the myocardium, resulting in a series of insufficiencies. Bloody manifestations, such as chest tightness, shortness of breath, and angina pectoris, affect the normal work of the heart to varying degrees. In severe cases, it can cause myocardial infarction or even death. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B17/12
CPCA61B17/12013A61B17/12031A61B17/12122A61B2017/00526A61B2017/12004A61B2017/12054A61B2018/00386
Inventor 李国庆余小林郭自同
Owner 李国庆
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