The invention discloses a biodegradable vascular anastomotic device, a special surgical instrument and a method of use thereof, which are used for anastomosis between human blood vessels, between artificial blood vessels, or between human blood vessels and artificial blood vessels. The vascular anastomosis device consists of a The first anastomotic ring/wheel and the second anastomotic ring/wheel are coaxial with each other, and the anastomotic ring/wheel includes a blood vessel support stent, a clamping stent, and anastomotic needles distributed circumferentially at the free end of the vascular support stent. The anastomosis surface of the blood vessel anastomosis device of the present invention has a coaxial geometric structure, the anastomosis is efficient, the anastomosis area is large, the success rate of the operation is improved and the collapse of the anastomotic stoma is reduced. The present invention is made of biodegradable materials. Through reasonable structural design, the vascular anastomotic ring/wheel can be degraded by the human body after operation, and maintain a relatively complete structure during the degradation process. Maintain the corresponding effective support time to maintain the function of the vascular anastomosis ring/wheel, and avoid the risk of foreign body residue caused by traditional mechanical anastomosis methods. The special instrument provided by the invention integrates the functions of clamping and anastomosis, which simplifies the operation process and improves the operation efficiency.