The invention relates to the technical field of nerve calming granules, and discloses
sugar-
free blood nourishing and nerve calming granules and a preparation method thereof.The
sugar-
free blood nourishing and nerve calming granules are composed of hairyvein agrimony, prepared
rehmannia roots,
vine of multiflower knotweed, yerbadetajo herbs,
rehmannia roots, suberect
spatholobus stems, cortex albiziae and
sugar-free auxiliary materials; comprising
microcrystalline cellulose,
isomaltitol,
mannitol,
nano silicon dioxide, Arabic gum, hydroxypropyl
methyl cellulose and
polyvinylpyrrolidone. By optimizing the proportion and
process conditions of the auxiliary materials and the synergistic effect of the medicinal material extract and the auxiliary materials, the
humidity of the wet granules is controlled to be 30-35%, the
granulation pressure is 3-6 MPa, the
drying temperature is 50-55 DEG C, and finally the granules with the particle size of 200-400 microns are prepared. According to the invention, the problems of poor particle
formability and insufficient disintegration performance caused by removal of sugar are overcome, rapid disintegration, good
formability and stability of sugar-free particles are realized, the
solubility and taste of the particles are improved, and the sugar-free granules are suitable for long-term administration by diabetics and sugar-sensitive people.