17 results about "Silk sutures" patented technology

The utility model relates to the technical field of medical instruments, in particular to an incision protection sleeve for thyroid surgery. The notch protection sleeve is made of an elastic strip-shaped material with a circular-arc-shaped section, a connecting structure (10) and a matching structure (20) are arranged at the two ends of the notch protection sleeve respectively, the two ends of the notch protection sleeve are connected to form a circular cylinder, the connecting structure (10) is two through holes formed side by side, and the matching structure (20) is two axial through grooves formed side by side; when the two ends of the protective sleeve coincide and are aligned, the two through holes are located in the inner sides of the two axial through grooves. According to the utility model, a simple structure is adopted, an operation silk thread and scissors are matched, an annular cylinder body which strictly corresponds to an incision in size can be formed, the ring diameter is continuously adjustable, the production cost is low, the use is convenient, the flaring function is realized, and the improvement of the operation adaptability is facilitated.

The utility model relates to the technical field of five-thread overedgers, and discloses a five-thread overedger with an adjustable tailstock, which comprises a mounting panel, a first adjusting component, a second adjusting component, a third adjusting component and a fourth adjusting component, and the first locking assembly is arranged on the outer side of the annular sleeve and used for increasing the dismounting speed of the pay-off assembly and the pay-off assembly. Height adjustment and angle adjustment are conducted on the thread stand through the first adjusting assembly and the second adjusting assembly according to actual conditions, so that a silk thread is driven to be in a tightened state all the time, the silk thread has a more suitable thread inlet angle, sewing work of an overedger body at different heights and different angles is facilitated, and the sewing efficiency is improved. The functionality of the overedger in a special scene and the practicability of the thread stand are expanded; and by arranging the first locking assembly and the second locking assembly, disassembly and assembly of the pay-off assembly, the wire outlet assembly and the wire guide assembly are facilitated, and quick disassembly and quick assembly between the wire frame assemblies are facilitated.

The application discloses a preparation method of barbed silk suture, which comprises the following steps: after degumming and activation, the silk suture is immersed in a ginsenoside finishing liquid for padding treatment, and then is baked and dried; the drug-loaded silk suture is put into a mold, a silk fibroin solution is poured into the mold, and after removing bubbles, the silk suture is dried; the dried silk suture is taken out and subjected to wet heat treatment to obtain the barbed silk suture; during the degumming process, an alkali solution with a mass concentration of 0.02-0.08% is used for degumming; and during the activation process, a strong alkali solution with a concentration of 5g / L-50g / L is used for activation. The preparation method of the barbed silk suture applies ginsenoside and silk fibroin to the production and formation of the barbed suture; the polysaccharide chain in the ginsenoside can form stable hydrogen bonds with the silk fibroin, so that the ginsenoside can act on a wound for a long time (long-term sustained release), the drug effect is prolonged, the inflammation of the wound is effectively improved, and the wound healing is promoted.

The anti-falling umbilical vein catheter comprises an umbilical vein catheter body with the inner end inserted into the body, a first buckle is embedded in the portion, located outside the body and close to the umbilical region, of the umbilical vein catheter body in a clamped mode, the first buckle is attached to the surface of the skin, and the first buckle and the skin are connected and fixed through a silk thread. A sterile gauze covering the umbilical vein catheter and the first buckle is laid on the abdomen of the child patient, a circle of wide bellyband is wound around the abdomen of the child patient and attached to the sterile gauze, a second buckle located on one side of the abdomen of the child patient is attached to the bottom of the wide bellyband in a pressing mode, and meanwhile the outer end of the umbilical vein catheter sequentially penetrates through the first buckle and the second buckle. When the wide-body bellyband is used, in order to prevent the umbilical vein catheter from falling off when the wide-body bellyband is loosened, the two connecting bands are arranged at the connecting end of the bellyband, in the dressing changing process, the half-winding section of the catheter can be temporarily transferred to the bottom of the connecting band which is not loosened, and the wide-body bellyband can further position and stabilize the sterile gauze.

The utility model relates to the technical field of medical equipment, and discloses a surgical suture fixing box which comprises a box body, a disinfection box is arranged in the box body, and a cover plate is connected to the outer side of the box body in a sliding mode. A wire bunching assembly is rotatably connected in the box, a wire pressing assembly is slidably connected to the outer side wall of the box, the wire pressing assembly comprises a bracket, a pressing rod is further slidably connected to the box, a pressing block is arranged at the bottom end of the pressing rod, and the bracket is further slidably connected with a protective sleeve matched with a wire; during use, the pressing block can be controlled to move downwards by pressing the pressing rod, silk threads are fixed through the dragging seat, when the silk threads need to be used again, the protective sleeve can be pushed to lift the pressing block through the inclined face on the pressing block, and then thread ends can be taken out. The fixing box has the advantage that the bevel gear set drives the rotating rod to control the movement of the operation line in the line guide tube, and the problem that after the operation line is cut off by a traditional fixing box, the line end is inconvenient to find again is solved.

The application discloses a barbed silk suture, which comprises a thread body in the inside, a silk surface body wrapped on the surface of the thread body, and a plurality of barbs protruding outward from the silk surface body; the barbed silk suture is prepared by the following method: after degumming and activation, the silk suture is immersed into a ginsenoside finishing liquid for padding treatment, and then baked and dried; the drug-loaded silk suture is put into a mold, a silk fibroin solution is poured into the mold, and after removing bubbles, the silk suture is dried; the dried suture is taken out and subjected to wet heat treatment to obtain the barbed silk suture. The barbed silk suture of the application applies ginsenoside and silk fibroin to the preparation and formation of the barbed suture; the polysaccharide chain in the ginsenoside can form stable hydrogen bonds with the silk fibroin, so that the ginsenoside can act on the wound persistently (long-term sustained release), prolong the drug effect, effectively improve the inflammation of the wound, and promote the wound healing.

The present application is about a preparation method of silk suture based on enzymatic grafting of chitosan oligosaccharide-protocatechuic acid, and relates to the field of medical antibacterial textile materials. In the present application, the chitosan oligosaccharide modified with protocatechuic acid is coupled with the degummed silk fiber by laccase promotion, and then the modified silk fiber is formed into a braided wire using a braiding machine, and finally the silver nanoparticles are stably deposited on the silk braided wire by amino-mediated reduction of silver ions, thereby achieving the excellent antibacterial properties of the silk braided wire. In this case, the antibacterial properties of the silk suture are improved by protocatechuic acid and chitosan oligosaccharide, and more silver nanoparticle deposition sites are provided; it is achieved that a suture can be completed on a medical braiding machine, the process adjustment is convenient, the thickness and length of the product are highly adjustable, no toxic chemical reagents are used, personal health is guaranteed, and it can be safely and widely used in medical, health and other fields.

This invention discloses a polyglycolic acid (PGA) suture-silk suture composite braided surgical suture and its preparation method. The suture is composed of two absorbable surgical sutures (PGA) and two non-absorbable surgical sutures (silk threads) in a multi-strand braided structure. The silk threads are black in color, and their main component is silk fibroin with a molecular weight greater than 30,000. The PGA sutures are pre-dyed with D&C Violet No. 2 dye before braiding, and then heat-set and sterilized with ethylene oxide after braiding. This invention utilizes the dense structure formed by the multi-strand braid to effectively prevent wound exudate from seeping into the suture interior, reducing the corrosive effect of liquid on the internal materials. Simultaneously, through the synergistic composite of PGA sutures and silk threads, a coordinated match is achieved between the suture's mechanical strength and degradation characteristics, resulting in a suture that combines stable support with suitable degradability, better meeting the needs of general soft tissue suturing and ligation in clinical practice.

The invention belongs to the technical field of medical materials, and relates to an antibacterial suture line for surgical suture and a preparation method thereof. The preparation method comprises the following steps: dissolving 2-amino-5-acetylpyridine in a hydrobromic acid glacial acetic acid solution, adding a bromine-containing acetic acid solution, and reacting to obtain an intermediate 1; adding the intermediate 1 into tetrahydrofuran, adding triethylamine and acetic anhydride, and reacting to obtain an intermediate 2; adding the intermediate 2 and thiourea into absolute ethyl alcohol to react to obtain an intermediate 3; adding the intermediate 3 and p-nitrobenzaldehyde into absolute methanol, and adding glacial acetic acid to react to obtain an intermediate 4; adding phosphorus oxychloride into N, N-dimethylformamide, and adding the intermediate 4 to react to obtain an intermediate 5; dissolving the intermediate 5 in a mixed solvent, and adding cystamine to react to obtain an antibacterial agent; the medical silk suture line is soaked in dimethyl sulfoxide dissolved with the antibacterial agent, and the medical silk suture line is obtained through ultrasonic treatment, soaking, rinsing and drying. The antibacterial suture line disclosed by the invention has multi-mechanism synergistic enhanced antibacterial performance, an environment response type active release mechanism and excellent interface affinity.

The application belongs to the technical field of medical materials and relates to a bacteriostatic suture for surgical suturing and a preparation method thereof. The preparation method comprises the following steps: 2-amino-5-acetylpyridine is dissolved in a hydrobromic acid glacial acetic acid solution, an acetic acid solution containing bromine is added, and an intermediate 1 is obtained through reaction; the intermediate 1 is added to tetrahydrofuran, triethylamine and acetic anhydride are added, and an intermediate 2 is obtained through reaction; the intermediate 2 and thiourea are added to anhydrous ethanol, and an intermediate 3 is obtained through reaction; the intermediate 3 and p-nitrobenzaldehyde are added to anhydrous methanol, and an intermediate 4 is obtained through reaction; phosphorus oxychloride is added to N,N-dimethylformamide, and the intermediate 4 is added to obtain an intermediate 5 through reaction; the intermediate 5 is dissolved in a mixed solvent, and cystamine is added to obtain an antibacterial agent; and the medical silk suture is immersed in dimethyl sulfoxide containing the antibacterial agent, and is subjected to ultrasonic treatment, soaking, rinsing and drying to obtain the bacteriostatic suture. The bacteriostatic suture has the advantages of multi-mechanism synergistic enhanced bacteriostatic performance, an environment-responsive active release mechanism and excellent interface affinity.

The application provides antibacterial and anti-inflammatory silk sutures loaded with natural active ingredients of clove and a preparation method thereof, and belongs to the technical field of silk suture materials. The antibacterial and anti-inflammatory silk suture comprises a silk suture base and an interface layer, a cross-linking anchoring layer, an active ingredient control layer of clove and a hydrophilic protective layer which are sequentially constructed from inside to outside on the surface of the silk suture base. The cross-linking anchoring layer is formed by cross-linking tannic acid on the surface of the silk suture base. Eugenol in the active ingredient control layer of clove is modified by microcapsule embedding, and gallic acid is cross-linked and grafted on the surface of the silk fiber through the cross-linking anchoring layer. The hydrophilic protective layer is a hyaluronic acid modified chitosan film layer. The antibacterial and anti-inflammatory silk suture realizes stable storage, firm loading and time-controllable release of plant active ingredients, and has mechanical properties, biocompatibility and triple synergistic effects of antibacterial, anti-inflammatory and promotion of wound repair.

The utility model provides an intrauterine device placer which comprises a handle, a push rod, a sleeve, a fixing assembly and an intrauterine device. The sleeve and the silk thread are fixed at the same time through the fixing assembly, and the plug on the limiting rod is clamped in the corresponding limiting hole in the sleeve, so that the sleeve is fixed; the button is provided with a threading hole for a silk thread to penetrate through, the button is limited through the lower fixing ring, the fixing ring is blocked at the threading hole when the spring naturally stretches out and draws back, at the moment, the silk thread is clamped between the upper fixing ring and the button, the function of fixing the silk thread is achieved, and when the spring is pressed down, the threading hole is located below the upper fixing ring, and the threading hole and the lower fixing ring are staggered. And the silk thread is not fixed any more, so that the intrauterine device can be placed. The degradation cone of the intrauterine device is inserted into the insertion column of the solid body and is in surface contact with the bottom of the degradation cone, so that the contact area is increased, the stress in the implanting process is reduced and dispersed, and the problem that the degradation cone is broken due to concentrated stress in the product implanting process is solved.

The utility model relates to the field of surgical suture needles and threads, and discloses a needle and thread assembly based on cervical cerclage surgical suture, which comprises a suture line and a suture needle, the cross section of the suture line is circular, the suture line comprises a main line section, and two ends of the main line section are respectively connected with a transition section. The diameter of the transition section is gradually reduced along the extension direction; the large-diameter end of the transition section is connected with the main line section; the small-diameter end of the transition section is connected with the needle threading section; according to the scheme, the main line section serves as a main body of the suture line, the diameter of the main line section is relatively large, the section of the main line section is round, and the problem that due to the fact that the suture line is thin, tension is large, and cutting wounds of the thin line to cervical tissue are likely to happen can be solved, and particularly under the condition that suture and binding retention time is long, the thin line is likely to damage the tissue and cause infection; the needle threading section is used for being connected with a suture needle, the diameter of the needle threading section is relatively small, the needle threading section can more conveniently penetrate into a needle eye of the suture needle, and compared with a thick thread, the thin thread is easier to knot.

A cavity suture channel expanding and guiding device is provided with a handle part and an expanding part used for forming an arc-shaped channel and expanding, and the expanding part and the handle part are integrally connected. A containing cavity used for containing suture lines or linear suture materials is formed in the expansion part. The expansion part is in an arc shape, the central angle of the arc shape is defined as A, and A is larger than or equal to 180 degrees and smaller than or equal to 270 degrees. The cavity suturing channel expanding and guiding device is simple in structure and low in cost, the arc-shaped channel is formed by the cavity suturing channel expanding and guiding device, the arc-shaped channel can be expanded, and therefore thick silk threads or linear suturing materials can penetrate through the arc-shaped channel conveniently.

The invention discloses a preparation method of a tussah silk medical suture with glucose response and healing promotion functions. The preparation method comprises the following steps: synthesizing 3-APBA and HA to prepare HA / 3-APBA; hA / 3-APBA, PVA and insulin are mixed to prepare hydrogel, a phenylboronic acid group is stably combined with a homeopathic glycol structure, so that an insulin drug is loaded in a hydrogel coating, glucose and PVA compete for the phenylboronic acid group in a hyperglycemia environment, the crosslinking degree of the hydrogel is reduced, and finally the hydrogel is degraded to release the drug. The preparation method comprises the following steps: weaving tussah silk to obtain a tussah silk suture line, degumming the tussah silk suture line, carrying out surface modification treatment on the suture line by using DA, and grafting drug-loaded hydrogel on the surface of the tussah silk suture line to form a uniform and stable coating on the surface of the suture line, thereby preparing the glucose-responsive and healing-promoting medical suture line.

The utility model provides a small incision skin traction hook which solves the problem that a special instrument used for a small incision of an ophthalmologic operation is lacked at present. A small incision skin traction hook is formed by sequentially connecting a ring part, a connecting part and a traction part, the front end of the traction part is provided with two hook claws bent towards the lower left, the traction hook is pulled through a silk thread fixed to the ring part, and the silk thread is fixed through hemostatic forceps or a fixing part.

The invention provides a rat periodontitis model and a construction method and application thereof, on the basis of ligating a tooth neck of a first molar of an SD (Sprague Dawley) rat by a traditional silk thread, light-cured composite resin is bonded in the occlusion direction of the silk thread to manufacture an appearance high point, the silk thread is fixed, a tartar is simulated, and an occlusion high point is formed; meanwhile, the gingival sulcus of the first molar of the upper jaw is cooperatively inoculated with human periodontitis pathogenic bacteria, the implementation method is simple, the repeatability is good, the stability is high, the silk thread loosening rate is reduced to 3.13% when modeling is carried out for 28 days, the loosening rate is greatly reduced compared with 34.38% of a traditional silk thread ligation model, subsequent experiment steps are simplified, lasting gingivitis cell infiltration is caused, and the method is suitable for popularization and application. The number of inflammatory cells is 63.27 + / -7.07% when modeling is carried out for 28 days, experimental periodontitis models of different degrees can be constructed within 2-4 weeks, compared with a traditional model, forming is faster, the model is closer to periodontitis clinical characteristics, and a model basis is provided for researching intervention strategies of different stages.