72 results about "Complication rate" patented technology

A system for administering a health care system, comprising up to five processing means and a database. The system accepts inputs from enrollees, insureds, providers, insurers and vendors, but requires no input from an administrator. The apparatus optionally includes devices for: measuring patient treatment outcomes, a “just-in-time” appointment rescheduler, an editable archive of prototypical treatment plans, measuring the diagnostic accuracy of diagnosing physicians and measuring the complication rate of treatment providers.

Minimal Invasive Spine Surgery (MISS) as a surgical approach is increasingly utilized because of the advantages it offers over conventional spine surgery. The smaller incision results in decreased tissue damage, less blood loss, decreased hospital stay & faster postoperative recovery. The drawbacks of MISS are the long learning curve of working through a smaller incision, longer length of surgery, & potential higher complication rate due to compromised visual field. These limitations can be overcome by more effectively using imaging and navigational devices. The pedicle device simplifies the hardest part of MISS instrumented fusion of conventional pedicle screw insertion by introducing a percutaneous temporary device to locate and create the channel for later conventional pedicle screw implantation using available imaging techniques. This results in faster conventional pedicle screw insertion with precision, thereby decreasing implantation error and minimizing soft tissue injury and blood loss, as well as neurological, vascular, and dural injuries and complications.

The invention relates to nutrition formula food applicable to a tumor patient, and aims at providing nutrition formula food which is applicable to the tumor patient and is prepared according to pathological characteristics of metabolic disorder of the tumor patient. The nutrition formula food applicable to the tumor patient, per 100kcal thermal content, comprises 3.8-5.8g protein or hydrolysate of the protein, 5.6-8.4g carbohydrate, 4.8-7.2g fat, 0.9-1.4g dietary fiber, 3.31-108.62mg vitamin complex, 0-40mg taurine and 0.33-2.333g complex mineral. The food has the main characteristics that the food contains unbalance amino acid, high protein, slow-release carbohydrate, and high fat, and has high energy density; the treatment effect of the patient is better than that of a patient supported by ordinary nutrition after the food provides clinical nutrition support for the patient undergoing lung cancer chemotherapy; and the complication rate of the patient is also obviously lower than that of the patient supported by the ordinary nutrition.

The invention discloses a modification method used for the surface of a magnesium alloy stent and contains controlledly degradable magnesium alloy stent surface micro-arc oxidation modification treatment and drug molecule biomimetic deposition; the magnesium alloy stent surface micro-arc oxidation modification treatment is first performed on the surface of magnesium alloy stent substrate to form controlledly degradable microporous ceramic oxide film with high porosity, the thickness of the film is 80-120mu m, the porosity is 20-40%; then drug molecule biomimetic deposition capable of promoting endothelial growth or dissolving thrombus and anticoagulating is performed on the microporous ceramic oxide film and the width of the settled layer is 5-10mu m. The modification of the surface of the magnesium alloy stent of the invention can effectively improve the in vivo biodegradation rate of the stent and the corresponding consistency of the mechanical property thereof, increase the compatibility between the stent and vascular walls, reduce the restenosis rate of blood vessels, lower the incidence of complications of patients and improve the survival rate and the life quality.

The present invention provides methods for treating alphavirus infections; methods of treating hepatitis C virus (HCV) infections; methods of treating West Nile virus infection; methods of reducing liver fibrosis; methods of increasing liver function in an individual suffering from liver fibrosis; methods of reducing the incidence of complications associated with HCV and cirrhosis of the liver; and methods of reducing viral load, or reducing the time to viral clearance, or reducing morbidity or mortality in the clinical outcomes, in patients suffering from viral infection. The methods generally involve administering effective amounts of an interferon receptor agonist and pirfenidone in combination therapy.

The invention relates to a method for implementing aortic stent in-vitro fenestration by virtue of a 3D printing model. The method comprises the following processing steps: acquiring CT or nuclear magnetism imaging data of aorta and branches of a patient, and processing the data into a data format which is recognizable for a 3D printer; transmitting the processed data to the 3D printer and printing the data by virtue of the printer; polishing an obtained mode; disinfecting the mold at normal temperature and keeping the disinfected mode on an operating table; placing an aortic stent graft in the mold, and making marks on the stent in accordance with positions and sizes of branched artery orifices; taking out the stent and conducting fenestration reforming in accordance with the marks; re-installing the reformed stent in a conveyor; and releasing the stent in vivo, and finally reconstructing branched arteries by virtue of a window. With the application of the method provided by the invention, the indication scope of an endovascular repair technology is widened, the efficiency and the accuracy of the aortic stent in vitro fenestration are enhanced, the occurrence rate of complications is reduced and operation safety is improved.

Lead Tracking of Implantable Cardioverter-Defibrillator and Cardiac Resynchronization Therapy Devices improve upon the process of implantation of ICD-CRT devices, placing their leads, and improving the information fed back to the device and / or clinician. Tracking of the placement of the leads during implantation is accomplished along with monitoring the leads once implanted. Benefits include reducing the risk and complication rate, simplifying implantation procedure, and enabling the extraction of vital data not previously available. Leads are tracked to at least minimize the need to use fluoroscopy. Three dimensional tracking (10) is employed to facilitate obtaining of data that allows the surgeon to better visualize lead insertion and placement. Placement of the leads during a procedure requires use of an external tracking component along with means and method for tracking the implantable leads. Transmitting antennas (10, 110) are provided, equal in number to the number of degrees of freedom of tracking required. A link (50) between the sensor (70) and the computation unit (40) can be wired or wireless. Once leads are implanted, heart wall motion must be monitored via the tracking of the leads within a clinical or home environment. Such tracking of the leads may be accomplished in real time.

The invention discloses a recyclable and adjustable interventional stent for constricting blood vessels, wherein the stent main body is divided into three parts; the stent is waist drum shape; the upper and lower parts of the stent are respectively provided with an expanding part, which has supporting and locating effects; and a part with changeable opening diameter is arranged in the middle of the stent. The expanding part at the upper end of the stent has no tectorial membrane or has tectorial membrane; the middle opening diameter changeable part and the upper half part of the expanding part at the lower end of the stent are covered with pericardium in anti-calcification treatment; and metallic line rings are threaded at the lowermost edge of the stent. A transportation composite conduit is composed of two parts of an epitheca and an inner core. The inner core is a hollow tube. An outer side wall at the tube sharping part has a wire-hanging groove for hanging metallic lines at inferior margin of the stent. The stent is used for replacing normal pulmonary banding so as to improve curative effect and reduce related complication rate and death rate. Adhesion is not formed around the cardio great vessels and pulmonary stenosis is not formed, so the difficulty of the radical operation is not increased. The stent is suitable for other situations for reducing artery blood flow and pressure.

Wound closure apparatus is provided including a body having an elongated, lowermost force-transmitting surface operable to be placed in a proximal, external, wound-closing position on a patient, together with a force-exerting assembly coupled with the body and operable to exert a downwardly directed force serving to generate wound-closing pressure against the patient's tissue. The force-transmitting surface is preferably three-dimensionally asymmetric so that forces of different magnitude are exerted at different locations along the length of the surface. The apparatus is especially designed for the closure of wounds attendant to endovascular interventions, e.g., a femoral artery puncture wound incident to percutaneous cardiac intervention (PCI), and is capable of quickly effecting wound closure with a time-to-ambulation (TTA) of approximately 60 minutes, and with a very low complication rate.

Wound closure apparatus is provided including a body having an elongated, lowermost force-transmitting surface operable to be placed in a proximal, external, wound-closing position on a patient, together with a force-exerting assembly coupled with the body and operable to exert a downwardly directed force serving to generate wound-closing pressure against the patient's tissue. The force-transmitting surface is preferably three-dimensionally asymmetric so that forces of different magnitude are exerted at different locations along the length of the surface. The apparatus is especially designed for the closure of wounds attendant to endovascular interventions, e.g., a femoral artery puncture wound incident to percutaneous cardiac intervention (PCI), and is capable of quickly effecting wound closure with a time-to-ambulation (TTA) of approximately 60 minutes, and with a very low complication rate.

Minimal Invasive Spine Surgery (MISS) as a surgical approach is increasingly utilized because of the advantages it offers over conventional spine surgery. The smaller incision results in decreased tissue damage, less blood loss, decreased hospital stay & faster postoperative recovery. The drawbacks of MISS are the long learning curve of working through a smaller incision, longer length of surgery, & potential higher complication rate due to compromised visual field. These limitations can be overcome by more effectively using imaging and navigational devices. The pedicle device simplifies the hardest part of MISS instrumented fusion of conventional pedicle screw insertion by introducing a percutaneous temporary device to locate and create the channel for later conventional pedicle screw implantation using available imaging techniques. This results in faster conventional pedicle screw insertion with precision, thereby decreasing implantation error and minimizing soft tissue injury and blood loss, as well as neurological, vascular, and dural injuries and complications.

The invention discloses a four-dimensional percutaneous biopsy puncturing instrument which comprises a main puncture needle and an auxiliary puncture needle, wherein a main puncture needle core is arranged inside the main puncture needle; a navigator is mounted at the end part of the main puncture needle core, and is connected with a displayer; the auxiliary puncture needle comprises an end part, a needle tube part, an elastic bending part and a needle tip part. Through the adoption of the technical scheme, an MSCT four-dimensional positioning data is adopted as a basis, three angular velocity sensors and one displacement sensor are used for fully reacting the four-dimensional spatial positions of the puncture needles through the data navigation, the spatial positions of the puncture needles can be displayed in a real-time manner, the puncture path and the needle inserting angle can be adjusted at any time, blood vessels and other vital organs can be effectively avoided, and the objective can be accurately punctured. A clinical experiment proves that the puncture accuracy rate is 99%, the complication occurrence rate is 15%, and the radiation dosage is reduced by 80%.

A system for fully automating the administration of a health plan. The system accepts inputs from enrollees, insureds, providers, insurers and vendors, but requires no physical data entry from the plan administrator. The system also features an automated methodology that measures patient treatment outcomes in terms of quality-adjusted life-years, by diagnosis and by medical treatment provider. The system also includes automated methods for: a “just-in-time” appointment scheduler, an editable archive of prototypical treatment plans, measuring the diagnostic accuracy of diagnostic physicians and for measuring the complication rate of treatment providers.

The invention discloses a traditional Chinese medicine composition for treating psoriasis. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 5-15 parts of radix paeoniae rubra, 3-9 parts of rhizoma curcumae, 10-20 parts of glabrous sarcandra herb, 10-20 parts of rhizoma smilacis glabrae and 5-15 parts of dark plum. The traditional Chinese medicine composition has the following benefits: the treating effect can be achieved by virtue of a relatively small dose, the toxicity is remarkably reduced, the traditional Chinese medicine composition takes effect relatively fast, and recurrence can be delayed; the traditional Chinese medicine has a more outstanding effect on common psoriasis (PASI 50 can reach 60%); especially for an early-onset psoriasis patient, such complications as cardiovascular events, psoriasis arfhropathica and diabetes can be reduced (for a patient who takes the traditional Chinese medicine composition, the complication rate can be lowered by 20%); therefore, the traditional Chinese medicine composition can remarkably improve the life quality of the psoriasis patients, and has a better effect.

The invention discloses a cingulum reparation device and an application method thereof and belongs to the technical field of mitral valve regurgitation treatment devices and application methods thereof. The device solves the problems of large treatment wound, high complication occurrence rate and the like in the prior art. The device comprises an outer sheath tube with a controllable bending angle, a puncture catheter which is arranged at the front end of the outer sheath tube, rivets which are arranged in the puncture catheter, connection threads which are connected to the rivets and an operating handle; when the rivets are fixed to a cingulum to be repaired, the connection threads can be pulled to adjust the distances between the rivets, and then the cingulum to be repaired is driven to shrink. According to the cingulum reparation device and the application method thereof, mitral valve regurgitation is subjected to cingulum reparative therapy by the catheter through minimally invasive intervention, the wound is small, the surgical complication occurrence rate is low, and the application range is wide.

Wound closure apparatus is provided including a body having an elongated, lowermost force-transmitting surface operable to be placed in a proximal, external, wound-closing position on a patient, together with a force-exerting assembly coupled with the body and operable to exert a downwardly directed force serving to generate wound-closing pressure against the patient's tissue. The force-transmitting surface is preferably three-dimensionally asymmetric so that forces of different magnitude are exerted at different locations along the length of the surface. The apparatus is especially designed for the closure of wounds attendant to endovascular interventions, e.g., a femoral artery puncture wound incident to percutaneous cardiac intervention (PCI), and is capable of quickly effecting wound closure with a time-to-ambulation (TTA) of approximately 60 minutes, and with a very low complication rate.

The invention discloses a nail bar correcting support assembly used for scoliosis, comprising a concave side nail bar correcting support and a convex side nail bar correcting support, wherein the concave side nail bar correcting support and the convex side nail bar correcting support respectively comprise a longitudinal connecting bar, a fixed pedicle screw is fixedly connected to the middle position (top vertebral concave side) of the longitudinal connecting bar of the concave side nail bar correcting support, three fixed pedicle screws are fixedly connected to the middle position (top vertebral convex side and up and down centrum convex side thereof) of the longitudinal connecting bar of the convex side nail bar correcting support, and more than one sliding pedicle screw is connected tothe positions, close to two ends, of the longitudinal connecting bars of the concave side nail bar correcting support and the convex side nail bar correcting support. The nail bar correcting support assembly is simple in structure, good in correction effect, capable of maintaining the correction effect and retaining spinal growth, small in minimally invasive operation wound, and capable of reducing the rate of complications such as spontaneous fusion and infection.

The embodiment of the invention discloses a covered stent and a using method thereof. The covered stent comprises an inverted-Y-shaped iliac branch main body, a first main body and a second main body. The iliac branch main body comprises a cylindrical metal support and a film covering the metal support, so do the first main body and the second main body. The far-end of the first main body is connected to the iliac branch main body, and the far-end of the second main body is connected to the near-end of the first main body. The iliac branch main body has a three-way structure, and comprises an aorta chimney and two iliac branches. The aorta chimney is connected to the far-end of the first main body. By employing the covered stent, risks of stent movement and inner-leakage caused by the butt connection of a conventional iliac stent and a bifurcation stent short leg can be avoided; the operation time is shortened; the operation difficulty is reduced, risks of complications such as blood vessel erosion, perforation and laceration can be reduced; the approach application occurrence rate can be substantially reduced; and the operation difficulty for a patient whose unilateral approach is badly tortuous and narrow is reduced. The covered stent can be placed based on a blood vessel anatomy configuration, the original iliac artery bifurcation is retained, and the contralateral intervention in a later period can be carried out more easily.

The invention discloses a Chinese herbal preparation for treating severe acute pancreatitis. According to the traditional Chinese medicine, the pathogenesis of the severe acute pancreatitis is due to lacking of soothing of the liver and gall and accumulation of damp and hot, flaming heat toxin and blocking stagnant heat inside are further developed, then the lung is compressed, or the pericardium is invaginated, or the blood network vessel is thermally burnt to cause the severe acute pancreatitis. The key of the pathogenesis is excess heat and blood stasis. Therefore, the Chinese herbal medicines of caesalpinia minax hance, glabrous sarcandra herb, souliea vaginata, Wilson barberry, abrus cantoniensis hance, desmodium styracifolium, all grass or root of tricarinate calanthe, rubus alceaefolius poir, polygonum cuspidatum, root of procumbent urena, and pericarpium citri reticulatae viride are chosen and decocted with water to prepare a decoction of herbal medicine; the clinical test in the hospital shows that the total effective rate is up to 96.9%, and the occurrence rate of complications is remarkably lower than that of a contrast group.

The invention relates to a Chinese medicine for treating the systemic lupus erythematosus, particularly the lupus nephritis and a method for preparing the same. The medicine consists of the following components of oldenlandia diffusa, barbat skullcap, redroot gromwell, glutinous rehmannia, root of red-rooted salvia, motherwort and scorpion. The medicine has effects of clearing away the heat-evil and expelling superficial evils and activating blood circulation to dissipate blood stasis and is mainly used to treat the systemic lupus erythematosus, particularly the lupus nephritis; moreover, by matching Western medicines such as glucocorticoid and immunodepressant, etc., the medicine can be used to jointly treat the systemic lupus erythematosus, which can improve the effect of the hormone and the immunodepressant in curing the systemic lupus erythematosus, lower the incidence rate of infecting the complication, lower the recurernce rate and the death rate and have the important clinical meaning. The medicine of the invention can be made in all medicament forms for clinical use, including the powder, the medicinal broth, the mixture, the oral taking liquid, the capsule, the pelletized granule and the concentrated pill, etc.

The invention relates to a novel drainage catheter with developing rings. The novel drainage catheter comprises the developing rings and a drainage catheter assembly, wherein the drainage catheter assembly comprises a front part and a back part; a front end part is arranged at the front end of the drainage catheter assembly; a tail end tip is arranged at the tail end of the drainage catheter assembly; the developing rings are respectively arranged at the front end of the drainage catheter assembly and a part, being 50 to 100 mm away from the tail end tip, of the drainage catheter assembly; each developing ring is tightly matched with the outer wall of the drainage catheter assembly. The novel drainage catheter has the beneficial effects that the developing rings can be clearly displayed in real time by ultrasound equipment and other imaging equipment, so that a doctor can track the position of the novel drainage catheter during catheterization, the problem that the drainage tube is not catheterized in a proper drainage area or complications are caused by repeated puncture after detaching of the drainage tube is solved, the one-time success rate of catheterization can be greatly improved, the incidence of the complications is lowered, and the pain of a patient is relieved; the structure is simple and reliable; the production is easy; the cost is low; the use is safe, convenient and reliable.

The invention discloses a traditional Chinese medicine composition for treating female endocrine disorders. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 20-30 parts of astragalus membranaceus, 20-30 parts of Chinese angelica, 10-15 parts of red paeony roots, 10-15 parts of szechuan lovage rhizome, 10-15 parts of motherwort herbs, 5-10 parts of motherwort fruits, 5-10 parts of Chinese-date, 5-10 parts of cherokee rose fruits, 5-10 parts of chinese ixora flower, 5-10 parts of conic gymnadenia rhizomes, 5-10 parts of bamboo shavings, 3-6 parts of saussurea involucrate, 4-8 parts of caulis kadsurae and 6-12 parts of licorice roots. The invention also discloses a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition for treating female endocrine disorders is a pure traditional Chinese medicine preparation and has significant curative effects on various of gynecological diseases such as irregular menstruation, dysmenorrheal, amenorrhea, hyperplasia of mammary glands and the like caused by endocrine dyscrasia and no obvious toxic side effects; the traditional Chinese medicine composition is quick in response, definite in curative effects, wide in medicine sources and low in cost; the effective rate is up to 92 percent, the normal tissue complication probability is small, the current problems can be resolved and the root causes can be eliminated, and the long-term effect is good.

The present invention provides methods of treating hepatitis C virus (HCV) infection; methods of reducing the incidence of complications associated with HCV and cirrhosis of the liver; and methods of reducing viral load, or reducing the time to viral clearance, or reducing morbidity or mortality in the clinical outcomes, in patients suffering from HCV infection. Also provided are methods of treating liver steatosis and liver fibrosis.

The invention discloses a traditional Chinese medicine formula for treating vascular headache, comprising the following components by weight parts of: Chinese angelica 5-10 parts, white peony root 10-14 parts, radix bupleuri 12-14 parts, Poria cocos 10-15 parts, bighead atractylodes rhizome 15-20 parts, pepper mint 6-10 parts, moutan bark 8-12 parts, cape jasmine 10-14 parts, Cyperus Rotundus L. 8-10 parts, Ligusticum wallichii 15-20 parts, chrysanthemum 10-12 parts, licorice 6-8 parts. The invention achieves the following advantages: 1, it belongs to traditional Chinese medicine preparation, is convenient for using and has no toxic and side effect. 2, it has a definite therapeutic effect, takes effect rapidly, has wide medicine source and low cost. 3, it has a high the effective rate up to 93%, low complication incidence rate, can treat principal and subordinate symptoms simultaneously with a good long time effect.

The invention discloses a catheter drainage device for biliary and pancreatic surgery. The catheter drainage device comprises T-shaped catheter that is made of a bile indwelling catheter and a curvedplate having concave middle part. The upper end of the bile indwelling catheter is fixedly connected with the middle part of the lower side of the curved plate. A pancreatic catheter is sleeved on theinterior of the bile indwelling catheter. The lower end of the pancreatic catheter penetrates through side wall of a diverter valve and extends to outside of the diverter valve. The upper end of thepancreatic catheter successively penetrates through the bile indwelling catheter and the side wall of the curved plate and extends to outside of the curved plate. According to the invention, the pancreatic catheter is sleeved on the interior of the bile indwelling catheter to combine the pancreatic catheter and the bile indwelling catheter into a whole, thereby reducing amount of punctures on abdominal wall of a patient and reducing incidence of leakage complications caused by placement of an abdominal drainage catheter. The curved plate of the T-shaped catheter is placed at a bilioenteric anastomosis, and then the T-shaped catheter can be stably fixed in the body of the patient, thereby avoiding occurrence of shedding phenomenon.

The invention discloses a traditional Chinese medicine composition for treating diabetes. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 25-35 parts of astragalus membranaceus, 20-30 parts of white peony root , 15-20 parts of rhizoma anemarrhenae, 12-16 parts of poria cocos, 12-16 parts of polygonatum kingianum , 5-10 parts of radix ophiopogonis, 5-10 parts of sedum verticallatum, 5-10 parts of euphorbia humifusa, 5-10 parts of Chinese ixora flower, 5-10 parts of Chinese trumpet creeper, 5-10 parts of caulis bambusae in taeniis, 4-8 parts of dens draconis, 4-8 parts of rabdosia rubescens, 3-6 parts of caulis kadsurae and 8-10 parts of liquorice. The invention discloses a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition for treating diabetes disclosed by the invention is pure traditional Chinese medicine preparation, has a remarkable curative effect and not obvious toxic and side effect on diabetes caused by endocrine dyscrasia, can be used for overcoming the problems that the conventional medicament for treating the diabetes is high in use amount of hypoglycemic medicines and insulin and is higher in cost and greater in side effect on a human body after long-term use, is quick in effect taking, extract in curative effect, wide in medicinal herb resource ad low in cost, has an effective rate as high as 92% and a low complication occurrence rate, can be used for treating both manifestation and root cause of disease, and has a good long-term effect.

The invention discloses a recyclable interventional stent for constricting blood vessels, which is made of memory-alloy meshes; the stent is waist drum shape; the expanding part at the upper end of the stent has no tectorial membrane or has tectorial membrane; the narrow part in the middle of the stent and the expanding part at the lower part of the stent are covered with pericardium in anti-calcification treatment; and metallic line rings are threaded at the lowermost edge of the stent. The recyclable interventional stent for constricting blood vessels is arranged on the pulmonary artery trunk through an interventional method; the pressure at the remote end of the pulmonary artery is reduced through the narrow part in the stent; when being necessary, the stent is recycled through the interventional method. The stent is used for replacing normal pulmonary banding so as to improve curative effect and reduce related complication rate and death rate. Adhesion is not formed around the heart and great vessels and pulmonary stenosis is not formed, so the difficult of the radical operation is not increased. The stent is suitable for other situations for reducing artery blood flow and pressure.

The present invention discloses a traditional Chinese medicine composition for treating psoriasis, the traditional Chinese medicine composition is prepared from materials in the following parts by weight: 5-15 parts of paeoniae radix rubra (red peony root), 3-9 parts of curcumae rhizoma (rhizoma zedoariae), 10-20 parts of sarcandrae herba (sarcandra glabra), 10-20 parts of smilacis glabrae rhizoma (glabrous greenbrier rhizome), 5-15 parts of mume fructus (black plum). The invention has the beneficial effects that the therapeutic effect can be achieved at a small dosage, the toxicity is significantly reduced, the onset is rapid, and the recurrence can be delayed. The effect is more prominent for psoriasis vulgaris (PASI50 up to 60%), especially for early onset patients. The incidence of complications such as cardiovascular events, psoriatic arthritis, diabetes and so on can be reduced (complication rate of the patients of early drug treatment is reduced by 20%), the quality of life can be significantly improved, and the effect is better.

The invention discloses a modification method used for the surface of a magnesium alloy stent and contains controlledly degradable magnesium alloy stent surface micro-arc oxidation modification treatment and drug molecule biomimetic deposition; the magnesium alloy stent surface micro-arc oxidation modification treatment is first performed on the surface of magnesium alloy stent substrate to form controlledly degradable microporous ceramic oxide film with high porosity, the thickness of the film is 80-120mu m, the porosity is 20-40%; then drug molecule biomimetic deposition capable of promoting endothelial growth or dissolving thrombus and anticoagulating is performed on the microporous ceramic oxide film and the width of the settled layer is 5-10mu m. The modification of the surface of the magnesium alloy stent of the invention can effectively improve the in vivo biodegradation rate of the stent and the corresponding consistency of the mechanical property thereof, increase the compatibility between the stent and vascular walls, reduce the restenosis rate of blood vessels, lower the incidence of complications of patients and improve the survival rate and the life quality.

Compositions and methods for reducing hepatitis C virus (HCV) replication are provided. Also provided are compositions and methods of treating an HCV infection; methods of reducing the incidence of complications associated with HCV and cirrhosis of the liver; and methods of reducing viral load, or reducing the time to viral clearance, or reducing morbidity or mortality in the clinical outcomes, in patients suffering from HCV infection.