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Chinese medicine for treating systemic lupus erythematosus and preparation thereof

A lupus erythematosus, systemic technology, applied in the treatment of lupus nephritis, traditional Chinese medicine for treating lupus nephritis and its preparation, treating systemic lupus erythematosus, treating systemic lupus erythematosus. The relationship between the ratio of drug raw materials and clinical efficacy and other issues, to achieve the effect of inhibiting the growth of human kidney fibroblasts, reducing the recurrence rate and mortality rate, and improving the efficacy

Active Publication Date: 2008-11-12
THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But, so far, do not see the report of the specific raw material proportioning relation of medicine described in the present invention and its clinical curative effect as yet.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Hedyotis diffusa 200 parts Comfrey 80 parts

[0035] Banzhilian 80 parts Motherwort 80 parts

[0036] Rehmannia 120 parts Salvia 120 parts

[0037] 17 whole scorpions

[0038] The preparation method of the powder: take each raw material according to the above weight, wash and remove impurities, dry, pulverize, sieve, and pack into bags.

[0039] The preparation method of the decoction: weigh each raw material according to the above weight, wash and remove impurities, add water to decoct and pack separately to obtain.

[0040] The preparation method of capsules: take each raw material according to the above weight, wash and remove impurities, extract twice with boiling water for 1 hour each time, filter, combine the filtrate, concentrate, add alcohol to 70% alcohol content, and stand for 12 hours; take the supernatant, recover the alcohol, concentrate to a thick paste; add starch, stir evenly, dry at low temperature, crush and sieve, and divide into empty hard capsule...

Embodiment 2

[0042] Hedyotis diffusa 800 parts Comfrey 250 parts

[0043] Banzhilian 250 parts Motherwort 250 parts

[0044] Rehmannia 380 parts Salvia 380 parts

[0045] Scorpion 53 servings

[0046] The preparation method of the powder: take each raw material according to the above weight, wash and remove impurities, dry, pulverize, sieve, and pack into bags.

[0047] The preparation method of the decoction: weigh each raw material according to the above weight, wash and remove impurities, add water to decoct and pack separately to obtain.

[0048] The preparation method of capsules: take each raw material according to the above weight, wash and remove impurities, extract twice with boiling water for 1 hour each time, filter, combine the filtrate, concentrate, add alcohol to 70% alcohol content, and stand for 12 hours; take the supernatant, recover the alcohol, concentrate to a thick paste; add starch, stir evenly, dry at low temperature, crush and sieve, and divide into empty hard caps...

Embodiment 3

[0050] Hedyotis diffusa 400 parts Comfrey 130 parts

[0051] Banzhilian 130 parts Motherwort 130 parts

[0052] Rehmannia 200 parts Salvia 200 parts

[0053] Scorpion 30 servings

[0054] The preparation method of the powder: take each raw material according to the above weight, wash and remove impurities, dry, pulverize, sieve, and pack into bags.

[0055] The preparation method of the decoction: weigh each raw material according to the above weight, wash and remove impurities, add water to decoct and pack separately to obtain.

[0056] The preparation method of capsules: take each raw material according to the above weight, wash and remove impurities, extract twice with boiling water for 1 hour each time, filter, combine the filtrate, concentrate, add alcohol to 70% alcohol content, and stand for 12 hours; take the supernatant, recover the alcohol, concentrate to a thick paste; add starch, stir evenly, dry at low temperature, crush and sieve, and divide into empty hard ca...

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PUM

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Abstract

The invention relates to a Chinese medicine for treating the systemic lupus erythematosus, particularly the lupus nephritis and a method for preparing the same. The medicine consists of the following components of oldenlandia diffusa, barbat skullcap, redroot gromwell, glutinous rehmannia, root of red-rooted salvia, motherwort and scorpion. The medicine has effects of clearing away the heat-evil and expelling superficial evils and activating blood circulation to dissipate blood stasis and is mainly used to treat the systemic lupus erythematosus, particularly the lupus nephritis; moreover, by matching Western medicines such as glucocorticoid and immunodepressant, etc., the medicine can be used to jointly treat the systemic lupus erythematosus, which can improve the effect of the hormone and the immunodepressant in curing the systemic lupus erythematosus, lower the incidence rate of infecting the complication, lower the recurernce rate and the death rate and have the important clinical meaning. The medicine of the invention can be made in all medicament forms for clinical use, including the powder, the medicinal broth, the mixture, the oral taking liquid, the capsule, the pelletized granule and the concentrated pill, etc.

Description

technical field [0001] The invention relates to a traditional Chinese medicine for treating systemic lupus erythematosus, in particular to treating lupus nephritis and a preparation method thereof. [0002] The traditional Chinese medicine of the invention has the effects of clearing heat and detoxifying, promoting blood circulation and removing blood stasis, and is mainly used for the treatment of systemic lupus erythematosus, especially lupus nephritis. It is also used to treat systemic lupus erythematosus in combination with western medicine such as glucocorticoids and immunosuppressants, which can improve the curative effect of hormones and immunosuppressants on systemic lupus erythematosus, reduce the incidence of infection complications and other side effects, and reduce the recurrence rate and mortality rate , has great clinical significance. Background technique [0003] Systemic lupus erythematosus (SLE) is a connective tissue disease that can affect multiple syste...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61P37/02A61P19/04A61P13/12A61K35/64A61K35/646
Inventor 阳晓李幼姬黄锋先
Owner THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIV
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