The invention provides a compound maltodextrin fructose beverage. Each liter of compound maltodextrin fructose beverage comprises, by weight, 100-110 g of maltodextrin, 10-20 g of crystalline fructose, 2.0-3.0 g of sodium citrate, 3.0-4.0 g of potassium citrate, 0.1-0.2 g of sweetening agent, 0.2-0.3 g of vitamin C, pH modifier, and the balance water, wherein the dosage of the pH modifier follows the standard of making the pH of the compound maltodextrin fructose beverage be 4.7-5.0. The compound maltodextrin fructose beverage contains carbohydrates and vitamin C, the energy of the beverage is high, and the beverage is rich in nutrition. The invention further provides a method for preparing the compound maltodextrin fructose beverage. The preparation method is simple and easy to operate. The compound maltodextrin fructose beverage is suitable for being drunk by a patient before an operation, so that the patient's energy storage under the conditions of an empty stomach is improved, the carbohydrate metabolism is maintained, postoperation insulin resistance is reduced, pre-operation thirst, hunger and anxiety are relieved, the patient's postoperation subjective symptom improvement awareness is improved, the thin and weak patient's weight loss is reduced, and hospital stay is shortened.