576results about "Microscale sensors" patented technology

A system for analyzing measurements performed on a biological subject, the system including one or more processing devices configured to acquire subject data at least in part captured by a measurement system including at least one substrate including a plurality of microstructures configured to breach a functional barrier of the subject and a sensor operatively connected to at least one microstructure, the at least one sensor being configured to measure response signals from the at least one microstructure, and analyze the subject data using at least one model to determine an indicator at least partially indicative of a physiological state of the subject.

A sensor system for optical detection of multiple analytes is discussed. An example system is presented that includes a plurality of lenses configured to receive individual light signals from analyte-sensing chromophores disposed on an array when the analyte-sensing chromophores are illuminated by light while being exposed to different specific analytes within an interstitial fluid. The system further includes at least one volume phase grating (VPG) communicatively coupled to at least one of the plurality of lenses and a detector communicatively coupled to the at least one VPG so that light signals from the analyte-sensing chromophores are focused by the plurality of lenses to the at least one VPG and transmitted to the detector. The detector being operable to generate spectra with each spectrum corresponding to an individual light signal from a single analyte-sensing chromophore.

An electrode arrangement for use with a system for performing measurements on a biological subject, the electrode arrangement including: at least one substrate; and, a plurality of plate microstructures extending from the substrate, the microstructures being configured to breach the stratum corneum of the subject and wherein the microstructures include electrodes to allow signals to be applied to and / or received from the subject via the microstructures.

A wearable device includes an accelerometer, at least three electrodes to detect electromyography signal, a communication circuitry, and a processor circuitry. A user wears a primary and a secondary wearable device on two limbs. When the user performs a two-hand gesture, the wearable devices detect a primary and a secondary movement pattern. The primary device recognizes the two-hand gesture from the primary and secondary movement pattern.

The invention discloses a measurement method, system and related device, the method is applied to first electronic equipment, the first electronic equipment comprises a first electrode group and a second electrode group, and the distance between the first electrode group and the second electrode group is greater than a first distance; under the condition that a first electrode group and a second electrode group are implanted into subcutaneous tissue, the method comprises the following steps: determining a first physiological parameter through the first electrode group; electrocardiosignals are determined through the first electrode set and the second electrode set. Therefore, the electrocardiosignal of the user can be obtained anytime and anywhere through the first electronic equipment, and one or more other physiological parameters (such as blood glucose, blood ketone, blood lactic acid and uric acid) of the user can be measured at the same time, so that the health monitoring efficiency is improved.

The present disclosure provides methods and systems for identifying a tissue characteristic in a subject. Identifying a tissue characteristic may comprise accessing a database comprising a first set of data from a first image obtained from a first tissue region of the subject and a second set of data from a second image obtained from a second tissue region of the subject; computer processing the first set of data and the second set of data to (i) identify a presence or absence of one or more features indicative of the tissue characteristic in the first image, and (ii) classify the subject as being positive or negative for the tissue characteristic based on the presence or absence of the one or more features in the first image; and generating an electronic report which is indicative of the subject being positive or negative for the tissue characteristic.

Embodiments herein relate to optical chemical sensor systems that can be wearable and include microneedle arrays. In an embodiment, a chemical sensing device is included having a set of microneedles and a sensor element. The sensor element can include a first low-index gel layer, a second low-index gel layer, and a chromoionophore sensing film disposed between the first low-index gel layer and the second low-index gel layer. In an embodiment, a delay layer can be disposed between the sensor element and the set of microneedles. An optical emitter can be configured to emit light into the sensor element. An optical detector can be configured to receive light from the sensor element. Other embodiments are also included herein.

A catheter system for controlled sympathectomy procedures is disclosed. A catheter system for controlled micro ablation procedures is disclosed. Methods for performing a controlled surgical procedure are disclosed. A system for performing controlled surgical procedures in a minimally invasive manner is disclosed.

The present application relates to an oral scanner system having an oral scanner constructed and / or arranged for performing a scanning procedure on at least a portion of an oral cavity of a subject using an oral health sensor, the oral health sensor is constructed and / or arranged for outputting oral health sensor data acquired during the scanning procedure; a processor constructed and / or arranged to receive the oral health sensor data to determine control data for an oral care device from the oral health sensor data; an oral care device, distinct from the oral scanner, the oral care device configured and / or arranged for performing oral care activities, the oral care device comprising at least two distinct operational settings, where the processor is coupled to a processor communicator and the oral care device has a device communicator, wherein the processor communicator and the device communicator are configured and / or arranged for at least one-way communication from the processor to the oral care device, and wherein the processor is configured and / or arranged to communicate the control data to the oral care device, and the oral care device is constructed and / or arranged to select at least one of the at least two operational settings based on the control data in an oral care activity performed by the oral care device after the scanning procedure.

According to an aspect there is provided a device for analyzing a speckle pattern from biological tissue, the device comprising:a light source configured to generate light for illuminating the biological tissue, such that the light is scattered by the biological tissue and forms the speckle pattern;a Fourier transform element configured to collect the light scattered by the biological tissue and to transform the collected light into a spatial Fourier domain at a Fourier plane of the Fourier transform element;a spatial bandpass filter arranged at the Fourier plane, the spatial bandpass filter being configured to selectively transmit light at a spatial position of the Fourier plane, the spatial position corresponding to a band of speckle sizes of the speckle pattern;a photosensitive detector configured to detect the light transmitted though the bandpass filter, wherein a signal output from the photosensitive detector comprises information on contrast of the speckle pattern.

Embodiments herein relate to an optical chemical sensor system that is wearable and includes a microneedle array. In one embodiment, the invention includes a chemical sensing device having a set of microneedles and sensor elements. The sensor element may include a first low refractive index gel layer, a second low refractive index gel layer, and a chromogenic ionophore sensing film disposed between the first low refractive index gel layer and the second low refractive index gel layer. In one embodiment, a retardation layer may be disposed between the sensor element and a set of microneedles. An optical emitter may be configured to emit light into the sensor element. An optical detector may be configured to receive light from the sensor element. Other embodiments are also included herein.

The technology disclosed in this patent document can be used to construct devices with opto-electronic circuitry for sensing and identification applications, to provide untethered devices for deployment in living objects and other applications, and to provide fabrication techniques for making such devices for commercial production. As illustrated by specific examples disclosed herein, the disclosed technology can be implemented to provide fabrication methods, substrates, and devices that enable wireless, inorganic cell-scaled sensor and identification systems that are optically-powered and optically-readout.

Featured are urodynamic catheters, intravaginal devices, and intrarectal devices, systems and kits thereof, and methods of using the devices, systems, and kits to observe pelvic floor movements in order to monitor bladder function in order to diagnose, treat, or prevent urinary incontinence disorders, such as urge incontinence and stress incontinence.

To provide an aerosol delivery device with functionality for sensing the pressure within an environment of the aerosol delivery devices.SOLUTION: An aerosol delivery device comprises a control component and a digital pressure sensor. The digital pressure sensor is configured to measure a pressure applied thereto, and generate a corresponding signal that indicates the pressure thus measured. The control component or the digital pressure sensor is further configured to control at least one functional element of the aerosol delivery device based on the pressure indicated by the corresponding signal, or a condition of the aerosol delivery device or a user thereof determined from the corresponding signal. Control of the at least one functional element includes output of the pressure or condition for presentation by a display.SELECTED DRAWING: Figure 2

A wearable biosensor for real-time quantification of a biomarker in a biofluid includes at least one functional module. The functional module includes an iontophoresis induction module, a microfluidic layer, a plurality of multimodal biosensors, and a paperfluidic layer.

Disclosed are devices, systems, and methods for in vivo monitoring of biological fluid flow within anatomical structures, such as blood flow through heart valves (e.g., mitral, tricuspid, and / or aortic valves) or heart chambers. The disclosed devices, systems, and methods can continuously measure and evaluate blood flow back and forth at the inlet of a heart valve to determine cardiac function or dysfunction and / or to compile with other monitored data that can be used to measure or predict secondary factors.

An implantable cardiovascular pressure sensing system can be used to measure blood pressure accurately and safely without any patient intervention. It can include a pressure sensor that makes blood pressure measurements, circuitry for processing and storing the blood pressure measurements, and an antenna for transmitting the processed measurements to an external device (i.e., a device not implanted in the patient). The circuitry can average blood pressure measurements and / or remove artefacts caused by patient motion that is sensed with an accelerometer integrated into implantable cardiovascular pressure sensing system. A multilayer ceramic / polymer coating forms a hermetic seal around the components, preventing leakage or contamination. The implantable cardiovascular pressure sensing system is very versatile: it can be implanted in a blood vessel, next to a blood vessel, in an aneurysm sac, or integrated with another medical implant, such as an Amplatzer septal occluder, and implanted into or next to another vascular structure.

To provide an aerosol delivery device with functionality for sensing a pressure within an environment.SOLUTION: An aerosol delivery device 100 comprises a control component 208 and a digital pressure sensor 248. The digital pressure sensor is configured to measure a pressure exerted thereon, and generate a corresponding signal that indicates the pressure so measured. The control component or the digital pressure sensor is further configured to control at least one functional element of the aerosol delivery device based on the pressure indicated by the corresponding signal, or based on a condition of the aerosol delivery device or a user thereof determined from the corresponding signal. Control of the at least one functional element includes output of the pressure or condition for presentation by a display.SELECTED DRAWING: Figure 2

An electrophysiology catheter with a distal electrode assembly having covered spine carrying a plurality of microelectrodes. One or more spines have preformed configurations including at least a first portion with a first curvature and a second portion with a second curvature, and may include a linear portion. The linear portion may be between the first and second portions. The linear portion may be distal of the first and second portions. One or more spines have a narrower portion so that different portions of the spine can have different flexibility with a degree of independence in flexibility from adjacent portions.

A method of providing a channel in nervous tissue filled with an aqueous gel for implantation of a microelectrode or other medical device lacking sufficient physical stability for direct implantation by insertion, comprises providing an apparatus comprising an oblong rigid pin covered by a dry gel forming agent; locating a target in the tissue; defining a straight insertion path a desired tissue insertion point and the target; aligning the pin with its end foremost with the insertion path; inserting the pin into the tissue to a position near or at the target; allowing sufficient time to pass for a gel to be formed around the pin, withdrawing the pin. Also disclosed is a corresponding channel; a method of implantation of a microelectrode or microprobe into nervous tissue via the channel; a corresponding method of implantation of living cells; a corresponding apparatus for forming the channel.

A manometric catheter probe includes a flexible printed circuit, one or more pressure sensor assemblies coupled to the flexible printed circuit along a length of the flexible printed circuit, and a first flexible sleeve. Each pressure sensor assembly includes a body. The body includes a central cavity configured to receive the flexible printed circuit and an annular recess of the body. Each pressure sensor assembly further includes a microelectromechanical systems (MEMS) sensor disposed in the annular recess, an electrical connector configured to electrically couple the MEMS sensor and the flexible printed circuit, and a first flexible sleeve disposed over the annular recess of the body. The first flexible sleeve includes a fluid configured to communicate pressure to the MEMS sensor, and a second sleeve is disposed over the pressure sensor assembly.

A method of monitoring a subject with an opto-physiological sensor system is described herein. The method comprises obtaining a model of the optical properties of at least one body tissue type to be monitored, wherein the model of the optical properties comprises a definition of static (DC) and dynamic (AC) components of transmitted optical power and a definition of a source-detector separation related to a normalised path length for an illumination source of the opto-physiological sensor: obtaining an indication of at least one physiological property of the subject from a wearable device worn by the subject: obtaining an indication of at least one physical variable from the wearable device worn by the subject; determining, using the opto-physiological model, how the at least one physical variable affects the at least one physiological property; and determining a corrected value for the physiological property based on the determination of how the at least one physical variable affects the at least one physiological property.

The embodiment of the invention relates to a method and system for detecting gestures of both hands. A wearable device includes: an accelerometer; the at least three electrodes are used for detecting the electromyographic signals; a communication circuit arrangement; and processor circuitry. A user wears a primary wearable device and a secondary wearable device on both limbs. The wearable device detects a primary movement mode and a secondary movement mode while the user performs a two-hand gesture. The primary device recognizes both-hand gestures from a primary movement mode and a secondary movement mode.

A high-density bioprobe array is provided comprising conductive or optical shanks. A method of making high-density bioprobe arrays also is provided. A bioprobe system using the array also is provided.

An integrated electrode structure can comprise a catheter shaft comprising a proximal end and a distal end, the catheter shaft defining a catheter shaft longitudinal axis. A flexible tip portion can be located adjacent to the distal end of the catheter shaft, the flexible tip portion comprising a flexible framework. A plurality of microelectrodes can be disposed on the flexible framework and can form a flexible array of microelectrodes adapted to conform to tissue. A plurality of conductive traces can be disposed on the flexible framework, each of the plurality of conductive traces can be electrically coupled with a respective one of the plurality of microelectrodes.

Smart gear, which includes electrically conductive fabric, is provided to monitor health parameters, conduct transactions, and generate power. For example, the smart gear may include one or more sensors coupled to the fabric and / or electrically conductive fibers woven into the fabric. The one or more sensors may monitor health parameters such as breathing patterns, sleep patterns, heart murmurs, and so forth. The smart gear may include one or more wireless regions that power electronic devices based on inductive charging.

Described herein are sensors for measuring various parameters. The sensors may be used in systems, devices, and methods for controlling blood flow or for measuring (e.g., monitoring) blood pressure, pH, or analyte levels such as a lactate level, an oxygen level, and / or a carbon dioxide level. The sensors may include a membrane configured to generate a measurable response (e.g., a change in an electrical signal such as resistance, capacitance, current, voltage) when the membrane interacts with a parameter of interest. In some instances, the sensors may include a piezoresistive MEMS subassembly. In other instances, the sensors may include an electrochemical membrane.

A method of monitoring a subject using a photophysiological sensor system is described herein. The method comprises: obtaining a model of optical properties of at least one body tissue type to be monitored, where the model of optical properties comprises a definition of static (DC) and dynamic (AC) components of transmitted optical power and a definition of a source-detector interval related to a normalized path length of an illumination source for the photophysiological sensor; obtaining, from a wearable device worn by the subject, an indication of at least one physiological characteristic of the subject; obtaining an indication of at least one physical variable from a wearable device worn by the object; determining how the at least one physical variable affects the at least one physiological characteristic using the photophysiological model; and determining a corrected value of the physiological characteristic based on the determination of how the at least one physical variable affects the at least one physiological characteristic.

The present disclosure provides an electronic device and method of manufacturing the same. The electronic device includes a first region, a second region, an electronic component, and a first sensing element. The second region is adjacent to the first region. The first region has a first pliability. The second region has a second pliability. The second pliability is greater than the first pliability. The electronic component is disposed at the first region. The first sensing element is disposed at the second region and electrically connected to the electronic component.

Described herein is an implantable device having a sensor configured to detect an amount of an analyte, a pH, a temperature, strain, or a pressure; and an ultrasonic transducer with a length of about 5 mm or less in the longest dimension, configured to receive current modulated based on the analyte amount, the pH, the temperature, or the pressure detected by the sensor, and emit an ultrasonic backscatter based on the received current. The implantable device can be implanted in a subject, such as an animal or a plant. Also described herein are systems including one or more implantable devices and an interrogator comprising one or more ultrasonic transducers configured to transmit ultrasonic waves to the one or more implantable devices or receive ultrasonic backscatter from the one or more implantable devices. Also described are methods of detecting an amount of an analyte, a pH, a temperature, a strain, or a pressure.