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677results about "Microscale sensors" patented technology

System and method for telemetrically providing intrabody spatial position

A telemetry system and method for providing spatial positioning information from within a patient's body are disclosed. The system includes at least one implantable telemetry unit which includes (a) at least one first transducer being for converting a power signal received from outside the body, into electrical power for powering the at least one implantable telemetry unit; (b) at least one second transducer being for receiving a positioning field signal being received from outside the body; and (c) at least one third transducer being for transmitting a locating signal transmittable outside the body in response to the positioning field signal.
Owner:REMON MEDICAL TECH

Particle-containing membrane and particulate electrode for analyte sensors

Systems and methods of use involving sensors having a particle-containing domain are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.
Owner:DEXCOM

Systems and methods for communicating with implantable devices

Systems and methods for communicating with an implant within a patient's body using acoustic telemetry includes an external communications device attachable to the patient's skin. The device includes an acoustic transducer for transmitting acoustic signals into the patient's body and / or for receiving acoustic signals from the implant. The device includes a battery for providing electrical energy to operate the device, a processor for extracting data from acoustic signals received from the implant, and memory for storing the data. The device may include an interface for communicating with a recorder or computer, e.g., to transfer data from the implant and / or to receive instructions for controlling the implant. The device is secured to the patient's skin for controlling, monitoring, or otherwise communicating with the implant, while allowing the patient to remain mobile.
Owner:REMON MEDICAL TECH

Methods, systems, and associated implantable devices for dynamic monitoring of physiological and biological properties of tumors

Methods of monitoring and evaluating the status of a tumor undergoing treatment includes monitoring in vivo at least one physiological parameter associated with a tumor in a subject undergoing treatment, transmitting data from an in situ located sensor to a receiver external of the subject, analyzing the transmitted data, repeating the monitoring and transmitting steps at sequential points in time and evaluating a treatment strategy. The method provides dynamic tracking of the monitored parameters over time. The method can also include identifying in a substantially real time manner when conditions are favorable for treatment and when conditions are unfavorable for treatment and can verify or quantify how much of a known drug dose or radiation dose was actually received at the tumor. The method can include remote transmission from a non-clinical site to allow oversight of the tumor's condition even during non-active treatment periods (in between active treatments). The disclosure also includes monitoring systems with in situ in vivo biocompatible sensors and telemetry based operations and related computer program products.
Owner:NORTH CAROLINA STATE UNIV +1

Method for monitoring intraocular pressure using a passive intraocular pressure sensor and patient worn monitoring recorder

A device for passively measuring intraocular pressure of a patient including an in vivo sensor and an instrument external to the patient for remotely energizing the sensor, thereby permitting the instrument to determine the intraocular pressure. The device directly and continuously measures the intraocular pressure of a patient. The in vivo sensor in the intraocular pressure monitor includes a capacitive pressure sensor and an inductive component. An instrument, external to the patient, measures the pressure, provides readout of the pressure values and determines the intraocular pressure.
Owner:THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE

High Q factor sensor

ActiveUS7147604B1Measure easily and safely and inexpensively and accuratelySimple monitoring methodCatheterDiagnostic recording/measuringPhysical propertyQ factor
A sensor for wirelessly determining a physical property within a defined space comprises an electrical resonance and has a high quality factor Q. The quality factor Q is sufficiently high that a signal generated by the sensor can be received outside the defined space. The sensor may optimally have a dielectric coating.
Owner:ST JUDE MEDICAL LUXEMBOURG HLDG II S A R L SJM LUX II

Hand held device for wireless powering and interrogation of biomems sensors and actuators

A compact, hand-held device for wireless powering, interrogation and data retrieval from at least one implanted sensor. The hand-held device includes an antenna for powering an implanted sensor and for receiving data from the implanted sensor to the hand-held device for at least one of storage, display or analysis. The hand-held device establishes electromagnetic coupling with a low radiating radio frequency power inductor in the implanted sensor at a predefined separation and the antenna geometry allows for the antenna to power, interrogate and retrieve data from the implanted sensor without strapping the hand-held device to a human body housing the implanted sensor The hand-held device optionally allows for activation of the implanted sensor only during interrogation and data retrieval.
Owner:NASA UNITED STATES OF AMERICA THE AS REPRSENTED BY THE ADMINISTATOR

Techniques to improve polyurethane membranes for implantable glucose sensors

The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.
Owner:DEXCOM

Techniques to improve polyurethane membranes for implantable glucose sensors

The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.
Owner:DEXCOM INC

System and method for monitoring pressure, flow and constriction parameters of plumbing and blood vessels

The present invention provides a system and method of quantifying flow, detecting a location of an obstruction and quantifying a degree of the obstruction in a pipe characterized in pulsatile flow. The method includes the steps of (a) attaching at least two spaced pressure sensors onto inner walls of the pipe; (b) using the at least two spaced pressure sensors for recording pressure records associated with each of the at least two pressure sensors within the pipe; and (c) using the pressure records for quantifying the pulsatile flow in the pipe, for detecting the location of the obstruction in the pipe and for quantifying the degree of the obstruction in the pipe.
Owner:TELESENSE

System and Method for Orthopedic Alignment and Measurement

At least one embodiment is directed to a system for measuring parameters of a skeletal system in positions of optimal alignment for implantation of an orthopedic device. The system comprises one or more position sensors (202, 204, 206, 208, 210, and 212), one or more measurement sensors (606), a processing unit (506), and a screen (502). The position and measurement sensors are in communication with the processing unit. Position and relational positioning information in conjunction with one or more parameter measurements is used to determine proper seating of an implant, device balance over a range of motion, and device stability. For example, measurement of loading over a range of motion can be used to determine the amount and type of adjustment required for an implant. The positional and measurement data is stored in a database and accessible to the processing unit (506) to aid the surgeon, hospital, and implant manufacturer.
Owner:ROCHE MARTIN

Motion/activity, heart-rate and respiration from a single chest-worn sensor, circuits, devices, processes and systems

A respiration monitoring device includes an accelerometer (210) for application to the chest, whereby acceleration is possible due to both non-respiratory body motion and respiration, and an electronic circuit (DSP) responsive to an acceleration signal from the accelerometer and operable to separate from the acceleration signal a heart signal, a respiration signal, and a substantially non-respiration body motion signal. Other devices, sensor articles, electronic circuit units, and processes are also disclosed.
Owner:TEXAS INSTR INC

Method and anchor for medical implant placement, and method of anchor manufacture

An anchor and procedure for placing a medical implant, such as for monitoring physiological parameters. The anchor includes a central body in which a medical implant can be received. arms and members extend radially from first and second ends, respectively, of the central body. Each member defines a leg extending toward distal portions of the arms to provide a clamping action. The anchor and its implant are placed by coupling first and second guidewires to first and second portions of the anchor, placing an end of a delivery catheter in a wall where implantation is desired, inserting the anchor in the catheter with the guidewires to locate the anchor within the wall, deploying the arms of the anchor at one side of the wall followed by deployment of the members at the opposite side of the wall, and thereafter decoupling the guidewires from the anchor.
Owner:UIM PRESSURE IMPLANT INC

Devices and methods for accelerometer-based characterization of cardiac synchrony and dyssynchrony

Systems and methods according to the invention employ an acceleration sensor to characterize the synchrony or dyssynchrony of the left ventricle. Patterns of acceleration related to myocardial contraction can be used to assess synchrony or dyssynchrony. Time-frequency transforms and coherence are derived from the acceleration. Information and numerical indices determined from the acceleration time frequency transforms and coherence can be used to find the optimal pacing location for cardiac resynchronization therapy. Similarly, the information can be used to optimize timing intervals including V to V and A to V timing.
Owner:CARDIOSYNC

System and method for directing and monitoring radiation

A system for monitoring, directing and controlling the dose of radiation in a medical procedure for irradiating a specific region of a patient's body. In its generic form, the system includes at least one sensor being implantable within, or in proximity to, the specific region of the patient's body, the at least one sensor being for sensing at least one parameter associated with the radiation. The system further includes a relaying device which is in communication with the sensor(s). The relaying device serves for relaying the information outside of the patient's body.
Owner:REMON MEDICAL TECH

Heart monitors and processes with accelerometer motion artifact cancellation, and other electronic systems

A heart monitor includes a single chest accelerometer (210), an analog signal conditioning and sampling section (215) responsive to said accelerometer to produce a digital signal substantially representing acceleration, and a digital processor (220) operable to filter the acceleration signal into a signal affected by body motion and to cancel the body motion signal from the acceleration signal, thereby to produce an acceleration-based cardiac-related signal. Other processes and electronic systems are also disclosed.
Owner:TEXAS INSTR INC

Appendage Mountable Electronic Devices COnformable to Surfaces

Disclosed are appendage mountable electronic systems and related methods for covering and conforming to an appendage surface. A flexible or stretchable substrate has an inner surface for receiving an appendage, including an appendage having a curved surface, and an opposed outer surface that is accessible to external surfaces. A stretchable or flexible electronic device is supported by the substrate inner and / or outer surface, depending on the application of interest. The electronic device in combination with the substrate provides a net bending stiffness to facilitate conformal contact between the inner surface and a surface of the appendage provided within the enclosure. In an aspect, the system is capable of surface flipping without adversely impacting electronic device functionality, such as electronic devices comprising arrays of sensors, actuators, or both sensors and actuators.
Owner:THE BOARD OF TRUSTEES OF THE UNIV OF ILLINOIS

Flexible and Scalable Sensor Arrays for Recording and Modulating Physiologic Activity

An implantable sensor array incorporates active electronic elements to greatly increase the number of sensors and their density that can be simultaneously recorded and activated. The sensors can be of various configurations and types, for example: optical, chemical, temperature, pressure or other sensors including effectors for applying signals to surrounding tissues. The sensors / effectors are arranged on a flexible and stretchable substrate with incorporated active components that allow the effective size, configuration, number and pattern of sensors / effectors to be dynamically changed, as needed, through a wired or wireless means of communication. Active processing allows many channels to be combined either through analog or digital means such that the number of wires exiting the array can be substantially reduced compared to the number of sensors / effectors on the array.
Owner:THE TRUSTEES OF THE UNIV OF PENNSYLVANIA

Ischemia detection

Techniques for detection and treatment of myocardial ischemia are described that monitor both the electrical and dynamic mechanical activity of the heart to detect and verify the occurrence of myocardial ischemia in a more reliable manner. The occurrence of myocardial ischemia can be detected by monitoring changes in an electrical signal such as an ECG or EGM, and changes in dynamic mechanical activity of the heart. Dynamic mechanical activity can be represented, for example, by a heart acceleration signal or pressure signal. The electrical signal can be obtained from a set of implanted or external electrodes. The heart acceleration signal can be obtained from an accelerometer or pressure sensor deployed within or near the heart. The techniques correlate contractility changes detected by an accelerometer or pressure sensor with changes in the ST electrogram segment detected by the electrodes to increase the reliability of ischemia detection.
Owner:MEDTRONIC INC

Acoustically powered implantable stimulating device

An implantable stimulation system comprises an implantable stimulator and a control device. The control device is configured to transmit acoustic waves to the implantable stimulator, and the implantable stimulator is configured to transform the acoustic waves into electrical current, and generate stimulation energy based on the electrical current. For example, the electrical current can be transformed into electrical energy that can be used to generate the stimulation energy. Or the electrical current can contain signals used to directly or indirectly control the generation of the stimulation energy.
Owner:REMON MEDICAL TECH

Delivery method and system for monitoring cardiovascular pressures

ActiveUS20060047205A1Reduce pulmonary hypertensionQuick feedbackCatheterAngiographyBlood flowPulmonary artery
A delivery method and system for noninvasively monitoring cardiac physiologic parameters used to evaluate patients with cardiovascular conditions. The system includes an implantable sensing device configured for chronic implantation in a cavity of the cardiovascular system, such as the heart, pulmonary artery (PA), etc. The method involves introducing the sensing device through a cardiovascular cavity that is upstream in the vasculature from the cavity where implantation is intended and has a larger diameter than the intended cavity, and thereafter blood flow through the cardiovascular system delivers the device to the intended cavity. The device is sized and configured so as to secure itself within the intended cavity when the device moves through the cavity to a point where the diameter narrows sufficiently to secure the device and so as to be oriented once secured to sense a pressure either within, upstream (wedge), or downstream (distal) of the cavity.
Owner:UIM PRESSURE IMPLANT INC

Estimation of blood flow and hemodynamic parameters from a single chest-worn sensor, and other circuits, devices and processes

An electronic monitoring device includes an electronic processor (520) having at least one signal input for body monitoring, and a memory (530) holding instructions for the electronic processor coupled to the electronic processor so that the electronic processor is operable to isolate a cardiac signal including cardiac pulses combined with other cardiac signal variations, and the electronic processor further operable to execute a filter (730) that separates a varying blood flow signal from the cardiac pulses and to output information (790) based on at least the varying blood flow signal. Other devices, sensor assemblies, electronic circuit units, and processes are also disclosed.
Owner:TEXAS INSTR INC

Detection of apex motion for monitoring cardiac dysfunction

InactiveUS20070032749A1Sensitive, immediate and accurateEarly diagnosisElectrotherapyPerson identificationCardiac dysfunctionMotion sensors
Systems, devices and methods for detecting and monitoring cardiac dysfunction. The devices include motion sensors for detecting signals representative of the total movement of the heart, and of the apex of the heart in particular.
Owner:THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV

System for monitoring conduit obstruction

ActiveUS7211048B1ElectrotherapyCatheterCatheter blockageEngineering
A system for non-invasively monitoring one or more physiological parameters such as pressure and / or pressure gradients in a cardiac conduit adapted for blood bypass flow. The system includes the conduit, at least one sensing device chronically located within the conduit, and a non-implantable readout device. The sensing device includes at least one inductor coil and at least one sensor for monitoring the one or more physiological parameters for diagnosis of the condition of the conduit after the conduit is implanted in a patient. The readout device includes at least one inductor coil allowing electromagnetic telecommunication and electromagnetic wireless powering of the sensing device through the inductor coil thereof.
Owner:UIM PRESSURE IMPLANT INC

Flexible Eye Insert and Glucose Measuring System

Disclosed is a flexible insert (100) for placement on the human eye, comprising a light source (110) in said insert such that light emitted from the light source is shielded from the human eye upon correct placement of the insert on the human eye, a light-responsive material (120) placed in the light path of the light source, said light-responsive material emitting light upon stimulation by the light from said light source, the intensity of said stimulated emission being sensitive to a chemical interaction of the light-sensitive material with an analyte of interest, a photodetector (130) for detecting the light emitted by the light-responsive material; and a transmitter (140) coupled to the photodetector for transmitting a photodetector reading. The insert may be used in conjunction with a reader for automated monitoring of an analyte of interest such as glucose in the tear fluid of its wearer.
Owner:NXP BV

Intraocular pressure measurement system including a sensor mounted in a contact lens

An apparatus (180) for measuring intraocular pressure (IOP) comprises a contact lens (40) including an inner surface (42) contoured to a surface portion (34) of an eye (36) and a sensor (10) disposed in the contact lens. The sensor (10) comprises a contact surface (14) for making contact with the surface portion (34) of the eye (36). The contact surface (14) includes an outer non-compliant region (16) and an inner compliant region (18) fabricated as an impedance element that varies in impedance as the inner compliant region changes shape. The sensor (10) further comprises a region of conductive material (38) electrically coupled to the impedance element of the compliant region (18) and responsive to an external signal for energizing the impedance element so that the IOP may be determined.
Owner:THE CLEVELAND CLINIC FOUND

Image-guided delivery of therapeutic tools duing minimally invasive surgeries and interventions

Imaged-guided therapy for minimally invasive surgeries and interventions is provided. An image-guided device includes an elongate tubular member, such as a catheter, an annular array of capacitive micromachined ultrasound transducers (cMUTs) for real-time three-dimensional forward-looking acoustic imaging, and a therapeutic tool. The therapeutic tool is positioned inside an inner lumen of the elongate tubular member and can be a device for tissue ablation, such as a high intensity focused ultrasound (HIFU) device or a laser. The HIFU device is operable at high frequencies to have a sufficiently small focus spot, thus a high focal intensity. The imaging annular array is also operable at high frequencies for good acoustic imaging resolution. The high resolution forward-looking imaging array, in combination with the high frequency HIFU transducer, provides a single image-guided therapy device for precise tissue ablation and real-time imaging feedback.
Owner:THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV

Capacitive micromachined ultrasound transducer and methods of making the same

A method of making a capacitive micromachined ultrasound transducer cell is provided. The method includes providing a carrier substrate, where the carrier substrate comprises glass. The step of providing the glass substrate may include forming vias in the glass substrate. Further, the method includes providing a membrane such that at least one of the carrier substrate, or the membrane comprises support posts, where the support posts are configured to define a cavity depth. The method further includes bonding the membrane to the carrier substrate by using the support posts, where the carrier substrate, the membrane and the support posts define an acoustic cavity.
Owner:GENERAL ELECTRIC CO
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