279results about "Microscale sensors" patented technology

A sensor system for optical detection of multiple analytes is discussed. An example system is presented that includes a plurality of lenses configured to receive individual light signals from analyte-sensing chromophores disposed on an array when the analyte-sensing chromophores are illuminated by light while being exposed to different specific analytes within an interstitial fluid. The system further includes at least one volume phase grating (VPG) communicatively coupled to at least one of the plurality of lenses and a detector communicatively coupled to the at least one VPG so that light signals from the analyte-sensing chromophores are focused by the plurality of lenses to the at least one VPG and transmitted to the detector. The detector being operable to generate spectra with each spectrum corresponding to an individual light signal from a single analyte-sensing chromophore.

A wearable device includes an accelerometer, at least three electrodes to detect electromyography signal, a communication circuitry, and a processor circuitry. A user wears a primary and a secondary wearable device on two limbs. When the user performs a two-hand gesture, the wearable devices detect a primary and a secondary movement pattern. The primary device recognizes the two-hand gesture from the primary and secondary movement pattern.

A catheter system for controlled sympathectomy procedures is disclosed. A catheter system for controlled micro ablation procedures is disclosed. Methods for performing a controlled surgical procedure are disclosed. A system for performing controlled surgical procedures in a minimally invasive manner is disclosed.

Embodiments herein relate to an optical chemical sensor system that is wearable and includes a microneedle array. In one embodiment, the invention includes a chemical sensing device having a set of microneedles and sensor elements. The sensor element may include a first low refractive index gel layer, a second low refractive index gel layer, and a chromogenic ionophore sensing film disposed between the first low refractive index gel layer and the second low refractive index gel layer. In one embodiment, a retardation layer may be disposed between the sensor element and a set of microneedles. An optical emitter may be configured to emit light into the sensor element. An optical detector may be configured to receive light from the sensor element. Other embodiments are also included herein.

A method of providing a channel in nervous tissue filled with an aqueous gel for implantation of a microelectrode or other medical device lacking sufficient physical stability for direct implantation by insertion, comprises providing an apparatus comprising an oblong rigid pin covered by a dry gel forming agent; locating a target in the tissue; defining a straight insertion path a desired tissue insertion point and the target; aligning the pin with its end foremost with the insertion path; inserting the pin into the tissue to a position near or at the target; allowing sufficient time to pass for a gel to be formed around the pin, withdrawing the pin. Also disclosed is a corresponding channel; a method of implantation of a microelectrode or microprobe into nervous tissue via the channel; a corresponding method of implantation of living cells; a corresponding apparatus for forming the channel.

A manometric catheter probe includes a flexible printed circuit, one or more pressure sensor assemblies coupled to the flexible printed circuit along a length of the flexible printed circuit, and a first flexible sleeve. Each pressure sensor assembly includes a body. The body includes a central cavity configured to receive the flexible printed circuit and an annular recess of the body. Each pressure sensor assembly further includes a microelectromechanical systems (MEMS) sensor disposed in the annular recess, an electrical connector configured to electrically couple the MEMS sensor and the flexible printed circuit, and a first flexible sleeve disposed over the annular recess of the body. The first flexible sleeve includes a fluid configured to communicate pressure to the MEMS sensor, and a second sleeve is disposed over the pressure sensor assembly.

A method of monitoring a subject with an opto-physiological sensor system is described herein. The method comprises obtaining a model of the optical properties of at least one body tissue type to be monitored, wherein the model of the optical properties comprises a definition of static (DC) and dynamic (AC) components of transmitted optical power and a definition of a source-detector separation related to a normalised path length for an illumination source of the opto-physiological sensor: obtaining an indication of at least one physiological property of the subject from a wearable device worn by the subject: obtaining an indication of at least one physical variable from the wearable device worn by the subject; determining, using the opto-physiological model, how the at least one physical variable affects the at least one physiological property; and determining a corrected value for the physiological property based on the determination of how the at least one physical variable affects the at least one physiological property.

The embodiment of the invention relates to a method and system for detecting gestures of both hands. A wearable device includes: an accelerometer; the at least three electrodes are used for detecting the electromyographic signals; a communication circuit arrangement; and processor circuitry. A user wears a primary wearable device and a secondary wearable device on both limbs. The wearable device detects a primary movement mode and a secondary movement mode while the user performs a two-hand gesture. The primary device recognizes both-hand gestures from a primary movement mode and a secondary movement mode.

An integrated electrode structure can comprise a catheter shaft comprising a proximal end and a distal end, the catheter shaft defining a catheter shaft longitudinal axis. A flexible tip portion can be located adjacent to the distal end of the catheter shaft, the flexible tip portion comprising a flexible framework. A plurality of microelectrodes can be disposed on the flexible framework and can form a flexible array of microelectrodes adapted to conform to tissue. A plurality of conductive traces can be disposed on the flexible framework, each of the plurality of conductive traces can be electrically coupled with a respective one of the plurality of microelectrodes.

A penis measurement system and method, wherein the system includes a user device and a penis measurement device. An external soft casing encases a main shell of the penis measurement device. When at least one strap of the external soft casing is strapped on a penis, the external soft casing fixes the main shell to be on top of the penis, allowing a detection airbag protruding from the main shell to press down onto the penis with a down-pressing pressure. The detection airbag deforms and presses onto a sensor chip in the main shell. A processing unit receives a pressure sensor signal from the sensor chip and a gyroscope signal from a gyroscope in the main shell, and accordingly outputs a hardness value and a gyroscope value to a user device through a communication unit. The system quantifies a hardness of the penis.

Aspects relate to mechanisms to control the effective optical path length through skin tissue for non-invasive optical spectroscopy measurements. An apparatus can include a path length control part configured to control the effective optical path length of diffusely scattered light transmitted through skin tissue to produce a target effective optical path length. The apparatus may further include a spectral sensor, a detector, and a light source configured to produce input light directed towards the path length control part or the spectral sensor. The detector is configured to obtain a spectrum of an analyte under test based on the diffusely scattered light. The spectral sensor is configured to either receive the input light, produce modulated light based on the input light, and direct the modulated light to the skin tissue, or to receive the diffusely scattered light from the skin tissue and obtain the spectrum using the detector.

The present invention discloses an intelligent, bioengineered wound dressing device that utilizes honey bee-derived therapeutic compounds integrated into a programmable, multi-layered delivery structure designed for sustained antimicrobial release and dynamic wound healing modulation. The device features microencapsulated honey, propolis, and beeswax components embedded within a biocompatible hydrogel matrix, supported by a control technique that processes real-time wound data acquired through embedded biosensors. The technique classifies healing phases, detects wound anomalies, and modulates therapeutic release through actuators based on environmental cues such as pH, temperature, and exudate levels. The system further includes a logic control unit capable of adaptive learning, remote data transmission, and wound trajectory logging, ensuring precise, patient-specific therapeutic delivery. By integrating natural antimicrobial agents with intelligent sensing and release architectures, the invention provides a responsive, self-optimizing wound care platform that enhances healing outcomes, reduces dressing intervention frequency, and improves clinical oversight through real-time therapeutic intelligence.

Provided is an acoustic processing apparatus in which a microelectromechanical systems (MEMS) device is effectively arranged. The acoustic processing apparatus includes an enclosure, a sound duct extending from the enclosure, and a MEMS device housed in the sound duct.

A device for measuring a pressure differential comprises a tube, at least one pressure sensor and a processor. The tube comprises a closed insertion portion for insertion into a body, the insertion portion having an insertion end and an internal bore in communication with ambient pressure via an opening in the tube. The sensor is located in or on the insertion portion and comprises an internally facing region in communication with the bore and an externally facing region in communication with an exterior of the tube. The processor is configured to provide a stimulus, which may be an electrical stimulus, to the pressure sensor so that when the stimulus is provided, the pressure sensor provides a measurable response wherein the processor correlates the response with the pressure differential between the exterior of the tube and the bore. The measurable response may be indicative of a change in pressure differential between the exterior of the tube and the bore. There may be a plurality of pressure sensors, in which case at least two of the sensors may have different resonant frequencies at the same pressure differential. The insertion portion may comprise at least one aperture sealed by at least one pressure sensor. The pressure sensor may comprise an electromechanical or micro-electromechanical material and may comprises a piezoelectric and / or electrocapacitive sensor. The externally facing region of the pressure sensor may comprise a coating, which may be electrically insulative.

Various embodiments of the present disclosure can include flexible catheter tip. The flexible catheter tip can include an inboard understructure that defines a tip longitudinal axis, wherein the inboard understructure can be formed from a first continuous element that includes a first rectangular cross-section. An intermediate inboard covering can be disposed about the first continuous element that forms a distal portion of the inboard understructure. An outboard understructure can extend along the tip longitudinal axis, wherein the outboard understructure can be formed from a second continuous element that includes a second rectangular cross-section. An intermediate outboard covering can be disposed about the second continuous element that forms a distal portion of the outboard understructure.

A system for monitoring anxiety of an individual includes a chair having at least a seat and a back, a base supporting the chair, and a first sensor disposed in at least one of the seat or the back. The first sensor is configured to, without being in direct contact with the individual, continuously obtain data related to a first physical characteristic from the individual seated in the chair. The first physical characteristic is one of respiration or pulse rate. The system further includes a display and a controller. The controller is configured to receive, in real-time, the data related to the first physical characteristic from the first sensor and compile a first metric from the received data. The first metric is configured to visually represent a change in the first physical characteristic. The controller is further configured to output the first metric to the display in realtime.

Measurements are performed on biological subjects by using microstructures to penetrate the functional barriers of the target. [Solution] A system for performing measurements on a biological object, comprising: at least one substrate 511 including a plurality of plate microstructures 512.1, 512.2 configured to penetrate the stratum corneum of the object; at least one sensor operably connected to at least one microstructure and configured to measure a response signal from at least one microstructure; and one or more electronic processing devices configured to perform at least one of the following: determine the measured response signal, provide an output based on the measured response signal, perform an analysis using at least part of the measured response signal, and store data indicating at least part of the measured response signal.

A catheter system for controlled sympathectomy procedures is disclosed. A catheter system for controlled micro ablation procedures is disclosed. Methods for performing a controlled surgical procedure are disclosed. A system for performing controlled surgical procedures in a minimally invasive manner is disclosed.

An implantable cardiovascular pressure sensing system can be used to measure blood pressure accurately and safely without any patient intervention. It can include a pressure sensor that makes blood pressure measurements, circuitry for processing and storing the blood pressure measurements, and an antenna for transmitting the processed measurements to an external device (i.e., a device not implanted in the patient). The circuitry can average blood pressure measurements and / or remove artefacts caused by patient motion that is sensed with an accelerometer integrated into implantable cardiovascular pressure sensing system. A multilayer ceramic / polymer coating forms a hermetic seal around the components, preventing leakage or contamination. The implantable cardiovascular pressure sensing system is very versatile: it can be implanted in a blood vessel, next to a blood vessel, in an aneurysm sac, or integrated with another medical implant, such as an Amplatzer septal occluder, and implanted into or next to another vascular structure.

Example systems, apparatuses and methods are disclosed for sensing a force applied by an external source in a fluid monitoring tube. An example system comprises a force sensing device and signal conditioning circuitry configured to be electrically coupled to the force sensing device. The example system further comprises a housing configured to enclose the force sensing device and the signal conditioning circuitry. The housing comprises a snap structure configured to attach the housing to a base plate and retain the force sensing device and the signal conditioning circuitry in the housing.

This application relates to an oral scanner system, the oral scanner system using at least one oral health sensor configured and / or arranged to output oral health sensor data obtained during a scanning procedure related to at least one oral health condition to perform a scanning procedure of at least a part of the oral cavity; a position detector configured and / or arranged to output position sensor data related to a position or location where the oral scanner is currently performing a scanning procedure or has performed a scanning procedure at a given time; a processor configured and / or arranged to receive the oral health sensor data and the position sensor data, process the position sensor data to determine at least one discrete position or location from at least two discrete positions or locations of at least a part of the oral cavity where the oral scanner is currently performing a scanning procedure or has performed a scanning procedure at a given time, and assign oral health data to the determined discrete position or location, or process the oral health sensor data to determine oral health data related to at least one oral health condition and assign the oral health data to the determined discrete position or location; and a feedback unit configured and / or arranged to provide feedback regarding the oral health sensor data and / or the oral health data for at least two discrete positions or locations during the scanning procedure.

The present application belongs to the technical field of neural interfaces, and specifically, to a neural interface having an auxiliary structure. The neural interface includes at least one flexible electrode and at least one auxiliary structure, and the flexible electrode is assembled to one side of the auxiliary structure. The present application provides a neural interface, in which the auxiliary structure has rigidity, and the flexible electrode is detachably assembled to the auxiliary structure, so that the flexible electrode can be easily implanted into neural tissue with the assistance of the auxiliary structure, and then the auxiliary structure can be removed to leave only the flexible electrode in the brain tissue. The flexible electrode can adaptively deform according to the expansion and contraction state of a blood vessel, thereby reducing damage caused by implantation.

A system for monitoring quantitative health data of a user, the system includes a stationary sensor device for monitoring a first set of quantitative health data of the user when the user is resting in bed; and a wearable tracker for monitoring a second set of quantitative health data of the user when the user is resting; wherein the wearable tracker is worn by the user; the first set and second set are sequential in time to obtain around-the-clock monitoring of the quantitative health data of the user.

A bioelectronic stent sensor system comprises a bioelectronic stent sensor device comprising a first hollow cylindrical lattice, and a second hollow cylindrical lattice attached to a first surface of the first lattice, comprising a biocompatible magnetoelastic micromesh (BMM), and a computing system communicatively connected to the bioelectronic stent sensor device, comprising a processor and a non-transitory computer-readable medium with instructions stored thereon, which when executed by a processor, perform steps comprising receiving readout current signals from the bioelectronic stent sensor device, and calculating a blood flow rate based on the readout current signals by establishing an empirical relationship between the readout current signals and a flow rate value. Related devices and methods are also disclosed.

Systems and methods are provided for determining an acceleration at a location of interest within one of a user's head and neck. At least one of linear acceleration data, angular acceleration data, angular velocity data, and orientation data is produced using at least one sensing device substantially rigidly attached to an ambient-accessible surface of the user's head. The location of interest is represented relative to a position of the at least one sensing device as a time-varying function. An acceleration at the location of interest is calculated as a function of the data produced at the sensing device and the time-varying function representing the location of interest. The calculated acceleration at the location of interest is provided to at least one of the user and an observer in a human-perceptible form.

Disclosed is a minimally-invasive sensing device for measuring or estimating respiratory biomarkers. The device contacts a target body fluid detects for at least one target analyte and outputs a signal representative of a concentration of the analyte, from which biomarker information is determined. The present disclosure also relates to methods and systems using measurements or estimations of respiratory biomarkers to assess patient respiratory state, and / or assist in providing respiratory therapy to a patient.

A system and method for monitoring body chemistry of a user, the system comprising: a housing supporting: a microsensor comprising a first and second working electrode, a reference electrode, and a counter electrode, and configured to access interstitial fluid of the user, and an electronics subsystem comprising a signal conditioning module that receives a signal stream, from the microsensor, wherein the electronics subsystem is configured to detect an impedance signal derived from two of the first working electrode, the second working electrode, the reference electrode, and the counter electrode; and a processing subsystem comprising: a first module configured to generate an analysis indicative of an analyte parameter of the user and derived from the signal stream and the impedance signal, and a second module configured to transmit information derived from the analysis to the user, thereby facilitating monitoring of body chemistry of the user.

A sensing system includes a microprobe, the microprobe including: a layered structure including: a sensing unit comprising a sensor including a working electrode, wherein the sensing unit has a first perimeter when viewed along a layering direction, includes a first material having a first toughness, and including a first side and a second side; a deformable layer configured to deform under stress and positioned on the first side of the sensing unit; a ductile layer positioned on the deformable layer opposite the sensing unit and having a second perimeter when viewed along the layering direction, the first perimeter being within the second perimeter, the ductile layer including a second material having a second toughness greater than the first toughness; a sensor-interface layer positioned on the second side of the sensing unit; and an encapsulant partially encapsulating the layered structure and mechanically isolating the layered structure from a surrounding environment.

This invention relates to a method and system for non-invasively monitoring central venous pressure, using a set of microneedles and micro-electromechanical systems, e.g., in heart failure. Herein, the microneedle-based sensor attaches to the skin at the neck of a subject to monitor central venous pressure, as it is a direct representative of filling pressures causing skin sub-surface strain.

An electrochemical sensor apparatus for introducing a needle electrode into the skin of a subject to contact a biological fluid or a tissue in the subject and detect a target analyte, and methods of producing the apparatus. The apparatus has a movable portion which urges the needle electrode in the subject's skin and at least two needle electrodes are selected from a library to provide the apparatus with a multiplexing capacity.