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Artificial blood vessel valved homograft conduit and production method thereof

A technology of artificial blood vessels and manufacturing methods, applied in the field of artificial blood vessels, to achieve the effects of simple process, superior performance, and easy molding

Active Publication Date: 2019-06-18
WUHAN YONGSEN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to overcome the defects of the above-mentioned artificial blood vessel with valve in the prior art, and provide an artificial blood vessel with valve and its manufacturing method. The artificial blood vessel with valve and the artificial blood vessel of the present invention are sutured with polymer , when the artificial blood vessel is implanted in the body, the valved tube can be implanted together, the process is simple, easy to shape, and has good biocompatibility

Method used

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  • Artificial blood vessel valved homograft conduit and production method thereof
  • Artificial blood vessel valved homograft conduit and production method thereof
  • Artificial blood vessel valved homograft conduit and production method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A kind of manufacture method of artificial blood vessel with valve pipeline, such as figure 2 As shown, the specific steps are as follows:

[0036] S1: Prepare a blood vessel sheet (polytetrafluoroethylene PTFE material), fold it in half, and suture several straight lines along the direction perpendicular to the folded line to form a valve with a row of pocket-shaped openings; in this example, suture The resulting valve has three pocket openings.

[0037] S2: An artificial blood vessel is provided, and one end of the artificial blood vessel is folded outward along the axial direction, so that the inner surface of the end faces outward.

[0038] S3: The valve prepared in step S1 is sutured on the inner surface of the outwardly folded end of the artificial blood vessel with its pocket structure facing outward; it is sutured along the circumferential direction of the artificial blood vessel.

[0039] S4: apply bio-glue on the surface of the suture in step S1 and step S3...

Embodiment 2

[0042] Such as image 3 As shown, this embodiment is basically the same as Embodiment 1, the difference is that step S1 is: prepare two blood vessel sheets, and the materials of the two blood vessel sheets are different, namely polyurethane PU and polytetrafluoroethylene PTFE. , put two blood vessel sheets together, and sew one side to connect the two, and then sew a number of straight lines along the vertical direction of the connected side to form a pocket-like structure with a row of openings valve. The thickness of the two blood vessel sheets can be different. When suturing the two blood vessel sheets, the side lengths of the blood vessel sheets on both sides of the pocket-shaped opening can also be different, so that the pocket-shaped opening is in an open state. .

Embodiment 3

[0044] This embodiment is basically the same as Embodiment 2, except that the materials of the two blood vessel sheets are the same, which is polyethylene terephthalate PET material.

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Abstract

The invention provides an artificial blood vessel valved homograft conduit and a production method thereof. The artificial blood vessel valved homograft conduit comprises an artificial blood vessel and a valve arranged in the artificial blood vessel and used for blocking, wherein the valve is in a skirt state extending in the central line direction of the artificial blood vessel; the valve is prepared through sewing of a tubular blood vessel material to the artificial blood vessel, one end of the blood vessel material is connected to the artificial blood vessel in the radial direction of the artificial blood vessel, and the other end is a free end; the whole vessel body part of the blood vessel material is sewn on the artificial blood vessel through multiple sewing threads, and the sewingthreads are parallel to the vessel body of the blood vessel material in the radial direction and arranged at intervals in the peripheral direction of the vessel body of the blood vessel material. Theartificial blood vessel valved homograft conduit is obtained through sewing of a high polymer material and the artificial blood vessel, the valved homograft conduit can be implanted when the artificial blood vessel is implanted into a human body, the process is simple, and the biocompatibility is good.

Description

technical field [0001] The invention relates to the technical field of artificial blood vessels; in particular, it relates to an artificial blood vessel with a valve and a manufacturing method thereof. Background technique [0002] Congenital heart disease is the most common type of congenital malformation, accounting for about 28% of various congenital malformations. The incidence of congenital heart disease is increasing year by year, and currently accounts for 0.4%-1% of the total number of live babies. Every year, there are 150,000 to 200,000 new patients in my country, and about 1 / 3 of them have right ventricular or left ventricular outflow tract obstruction. Tetralogy of music, right ventricular double outlet, pulmonary atresia or common arterial trunk and other diseases, it is necessary to reconstruct the right ventricular outflow tract with artificial vascular catheter or valved vascular piece. [0003] The research on artificial vascular valved conduits has become a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/06
CPCA61F2/062A61F2220/0075A61F2/2475A61F2/2415A61F2240/001A61F2310/00005
Inventor 欧阳晨曦严拓刘思诗焦培刘雅文龙行
Owner WUHAN YONGSEN BIOTECH
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