A method of manufacturing a therapeutic material incorporating a soft thermoformable
elastomer with a
phase change material exhibiting high
latent heat of fusion. The compound provides elasticity, softness,
formability, and heat over an extended duration and to facilitate prolonged
skin contact at elevated temperatures. Used in combination with active ingredients the increased temperature and
formability provides enhanced transdermal delivery through the
skin.
Thermoplastic elastomers may be manufactured by mixing together plasticizing oil, a triblock
copolymer, a paraffinic substance and one or more additives, e.g., an
antioxidant, an
antimicrobial agent, and / or other additives to form a mixture which melted then cooled into the
thermoplastic elastomer. During cooling, the
thermoplastic elastomer may be molded or otherwise formed into any number of articles including, but not limited to, prosthetic liners, prosthetic sleeves, external
breast prostheses, breast enhancement bladders, masks,
wound dressing sheets,
wound dressing pads,
socks, gloves,
malleolus pads, metatarsal pads, shoe insoles, urinary catheters, vascular catheters, and balloons for medical catheters both vascular as well as urinary. Active ingredients are preferably added to the cooling
thermoplastic elastomer when the temperature is below 100° F. to prevent heat degradation and / or breakdown of vital proteins.