The invention provides a fishing rod with anesthesia, which can be used for automatically spraying anesthetic solutions into fish mouths. The fishing rod comprises a fishing rod body, a solution pressing device, a hollow fishing line, a hollow fishhook, an elbow and a float, wherein a solution injecting device comprises a casing, a piston, a piston rod, a big spring, a small spring, steel balls, a sealing ring and the anesthetic solutions; the tip end of the fishing rod is connected with the elbow, and the handle end of the fishing rod is connected with the solution pressing device; the sealing ring, the anesthetic solutions, the big spring, the piston, the piston rod, the small spring and the steel balls are arranged in the casing; two holes are formed in the external circle of the piston in the symmetric positions, and the small spring and the steel balls are mounted in the holes; a hemispheric groove is formed in an inner hole of the casing, one halves of the steel balls are mounted in an external circle hole of the piston, and the other halves of the steel balls are mounted in the hemispheric groove of the inner hole of the casing; the big spring is mounted behind the piston, the piston rod penetrates through the sealing ring to be exposed, a long hole is formed in the center of the piston rod, one end of the long hole is communicated with the anesthetic solutions, one end of the hollow fishing line penetrates through the elbow to be bonded with the other end of the long hole of the piston rod, the other end of the hollow fishing line is bonded with the hollow fishhook, and the float is mounted on the hollow fishing line. For the fishing rod with the anesthesia, when a big fish is hooked, the anesthetic solutions can be automatically sprayed into the fish mouth to anesthetize the fish, and the fish can be easily pulled to the shore.