The invention discloses mouth wash capable of preventing and treating dental ulcer. The mouth wash is prepared from the following components in parts by weight: 8-12 parts of hydroxyethyl cellulose, 4-6 parts of metronidazole, 0.1-0.3 part of procaine, 0.1-0.3 part of hexadecadrol, 6-10 parts of polyving akohol, 3-5 parts of oleum menthae, 3-5 parts of succus aloes folii siccatus, 4-6 parts of borneol, 8-10 parts of honeysuckle flowers, 4-6 parts of rhizoma coptidis, 4-6 parts of radix isatidis, 4-6 parts of folium isatidis, 3-5 parts of radix zanthoxyli, 2-4 parts of sandalwood oil, 5-9 parts of bamboo salt, 0.8-1.2 parts of vitamin B12, and 80-100 parts of deionized water. For the mouth wash, the method of combining the traditional Chinese medicine and the western medicine is adopted, and the Western medicinal ingredients are utilized for rapidly killing bacteria and diminishing inflammation, relieving swelling and pain, and repairing the mucosal tissue; the traditional Chinese medicinal ingredients are utilized for clearing away heat and toxic materials, cooling blood and purging fire, and consolidating the curative effects, so that the repeated attack of dental ulcer is prevented. The mouth wash can be used by replacing medicines in daily life, the healing of ulcer is accelerated, and the relapse of dental ulcer is prevented.