52 results about "Kasugamycin" patented technology

A kasugamycin organic acid salt and a use thereof, and a pesticide composition containing the kasugamycin organic acid salt and a use thereof. The composition exhibits good solubility in an aqueous solvent, without producing floccules or precipitates. The variety of kasugamycin mixed formulations is effectively expanded and the problem of resistance easily arising from single-agent formulations is avoided.

The invention relates to a Zhongshengmycin production strain and application of the Zhongshengmycin production strain, the strain is streptomyces sp. ZS-2, the Zhongshengmycin production strain has good Zhongshengmycin production activity, and a fermentation product has higher bacteriostatic activity and a wider bacteriostatic range.

This invention relates to the field of agricultural pest control, and particularly to a compound nanogel sustained-release agent, its preparation method, and its application. This invention provides a compound nanogel sustained-release agent comprising bromonitol, a synergist, a carrier material, and a cross-linking agent, wherein the synergist includes one or more of kasugamycin, amino oligosaccharides, thiazolium zinc, and copper hydroxide. This invention prepares a nanogel sustained-release agent by compounding bromonitol and the synergist, which has significant preventive effects against plant bacterial diseases such as bacterial wilt, bacterial angular leaf spot, canker, and soft rot. Furthermore, the compound nanogel sustained-release agent of this invention has small particle size, stable physicochemical properties under cold and heat, good dispersibility in water, no particle agglomeration, no particle size increase, a decomposition rate of less than 5%, a long-lasting effect, good safety, is not prone to inducing drug resistance, requires a small dosage, and simultaneously increases yield and efficiency.

The invention relates to the technical field of pesticides, and particularly discloses a biopesticide containing kasugamycin and application of the biopesticide containing kasugamycin. The preparation method comprises the following steps: obtaining a seed solution, fermenting, acidifying, adsorbing and separating, concentrating and crystallizing, and grinding kasugamycin, an auxiliary agent and water in a mass ratio of (3-4): (1-1.5): (4.5-6) to obtain the biological pesticide containing kasugamycin. The biopesticide containing kasugamycin provided by the invention is environment-friendly and safe, accurate in target and not easy to generate drug resistance, and can meet green agricultural requirements.

The invention belongs to the technical field of pesticide sterilization, and discloses a pesticide composition and application thereof.The pesticide composition comprises an active ingredient A and an active ingredient B. The active ingredient A is Cyclobutrifluram, the active ingredient B is any one of tetramycin, validamycin, phenazino-1-carboxylic acid or kasugamycin, and the active ingredient B is one of cyclobutrifluram, validamycin, phenazino-1-carboxylic acid and kasugamycin. The mass ratio of the active component A to the active component B is (1: 48)-(1: 52). The pesticide composition disclosed by the invention has an obvious synergistic effect on pathogenic bacteria and is harmless to target crops and other organisms.

The invention provides an agent for preventing and treating peanut bacterial wilt and a preparation method and application thereof, and belongs to the technical field of pesticide preparations, and the agent is a composite agent formed by scientifically compounding albendazole, carbendazim, kasugamycin, chlorobromoisocyanuric acid, chitosan oligosaccharide, amino-oligosaccharin, a seaweed extract, humic acid, palygorskite and trace elements. According to the invention, efficient inhibition of ralstonia solanacearum is realized, peanut system resistance is obviously activated, root development is promoted, rhizosphere microenvironment is improved, slow release of active components is realized by means of palygorskite, and the pesticide effect period is prolonged. Field trials show that the prevention and control effect reaches 84% or above, the yield increasing rate exceeds 22%, and the composition is environmentally friendly and high in safety. The bactericidal composition can be prepared into a water suspending agent or a dispersible liquid, is suitable for various application modes such as root irrigation and spraying, has the advantages of long lasting period and low resistance risk, and is suitable for large-scale popularization in green agriculture.

The invention discloses an acid stimuli-responsive bactericidal controlled-release agent and a one-step preparation method thereof. The method comprises the following steps: dissolving trivalent and divalent metal nitrates in deionized water to prepare a solution A, dissolving kasugamycin in a sodium hydroxide solution to prepare a solution B, and synchronously dropwise adding the solution A and a 2M sodium hydroxide solution C into the solution B to prepare the controlled release agent. The obtained controlled release agent has good acid stimulus response release characteristics, can realize matching of pesticide release time and pest occurrence period, reduces invalid release and premature loss of pesticides, prolongs the lasting period of the pesticides, reduces pesticide application times, and makes plant disease prevention and control more intelligent and precise. The loaded medicine not only exerts biological activity, but also is a main component of the composition material, and the reaction does not need heating, a non-inert environment, aging and an organic solvent, so that the preparation method is greener, simpler and more efficient, and is beneficial to popularization and application.

The invention discloses preparation and application of furoic acid and a bactericidal composition thereof, and relates to the technical field of biopesticides, the furoic acid comprises furoic acid, the chemical structural formula of the furoic acid is shown in the specification, the purity is greater than or equal to 98%, and the furoic acid is prepared by the following steps: mixing furfural, a sodium hydroxide aqueous solution and copper oxide, introducing oxygen at 50-60 DEG C, stirring and reacting for 4-6 hours, and filtering to obtain a filtrate; extracting, acidifying, recrystallizing and drying to obtain furoic acid; according to the preparation and application of the furoic acid and the bactericidal composition thereof, the furoic acid with a specific structure is scientifically compounded with screened specific biopesticides (kasugamycin, boscalid and ningnanmycin), and the ratio range (for example, the ratio of furoic acid to kasugamycin is 1: 10-10: 1) with a remarkable synergistic effect is optimized and determined; according to the composition disclosed by the invention, the components are effectively complemented on the action mechanism, and the defects that the traditional single pesticide is single in action target and easy to induce drug resistance are overcome, so that the overall control effect of the composition on various plant diseases (including bacteria, fungi and virus diseases) is remarkably improved.

The present invention relates to the field of nanopesticides, in particular to preparation of a nano suspension dispersion liquid which belongs to a pesticide variety insoluble in water and a solvent, and has the particle size smaller than 100 nanometers, especially smaller than 50 nanometers. A prochloraz manganese salt / kasugamycin nano suspension dispersion liquid having the particle size of 100 nanometers or less of the present invention is formed by mixing and diluting three components with water.

The invention relates to a composition for preventing and treating plant diseases and application thereof, and belongs to the technical field of disease and pest control. The invention provides a composition for preventing and treating plant diseases. The composition is prepared from the following components in parts by mass: 5 to 15 parts of eugenol, 1 to 10 parts of fructus psoraleae extract, 2 to 8 parts of litsea cubeba extract and 6 to 12 parts of kasugamycin. According to the scheme, the components of the composition have a synergistic effect and have a remarkable bactericidal effect on various plant disease pathogenic bacteria, the prepared preparation has a good control effect on plant diseases and can control disease indexes, the dosage of the preparation is remarkably reduced compared with that of a conventional agent, and the cost of disease and pest control is greatly saved.

The invention relates to the field of agricultural antibiosis, in particular to a composition containing long-chain unsaturated fatty acid amide and kasugamycin and a preparation method thereof.The composition comprises the long-chain unsaturated fatty acid amide, modified kasugamycin and other effective ingredients, the long-chain unsaturated fatty acid amide is specifically combined with T3SS core protein HrcC, and the modified kasugamycin is specifically combined with T3SS core protein HrcC; the injection body assembly is blocked, and the effect protein secretion is inhibited; kasugamycin can cause that bacteria cannot synthesize necessary functional proteins and die. The two components have a synergistic effect and can exert power at the same time from two aspects of inhibiting bacterial toxicity secretion and basic metabolism, so that the control effect on plant bacterial diseases is effectively improved. In practical application, the composition can greatly reduce damage of diseases to crops, guarantee healthy growth of the crops and improve the yield and quality of the crops, and has a wide application prospect.

The invention discloses a composite systemic bactericidal composition and application thereof in response to curved-surface water, fertilizer and pesticide regulation in pepper planting, and belongs to the technical field of pesticide bactericides. The composition is formed by compounding kasugamycin, chloroisobromine cyanuric acid and metalaxyl-hymexazol according to a specific mass ratio, water and fertilizer application parameters such as the irrigation amount, the fertilization amount and the pesticide application amount are optimized in combination with a response curved surface, cooperative prevention and treatment of pepper root rot are achieved, and water and fertilizer resources are efficiently utilized. The control effect is higher than that of a single agent, the dosage is small, and the bactericidal spectrum is expanded. The problems of resource waste and environmental pollution caused by a traditional large-water and large-fertilizer mode are remarkably relieved while high yield and high quality are guaranteed. The composite systemic bactericidal composition is applied to pepper planting response curved surface water, fertilizer and pesticide regulation, the pepper yield and the water and fertilizer utilization efficiency are improved, the disease index of root rot is remarkably reduced, and the contradiction between resource waste and frequent diseases in a traditional mode is solved.

This invention relates to a compound antibacterial agent and its application in open plant tissue culture. The active ingredients of the compound antibacterial agent include rifampin, kasugamycin, ticarcillin sodium clavulanic acid, and tetrachloroisophthalonitrile. The compound antibacterial agent can synergistically inhibit Agrobacterium rhizogenes or Rhodotorula glutinis, contaminating bacteria that are easily generated during plant tissue culture.

The invention discloses a substance with both disease resistance and plant growth regulation activity, and particularly relates to a sulfonamide-containing abietic acid derivative, the general formula of the derivative is as follows: # imgabs0 #, wherein R is N-(4, 6-dimethyl pyrimidine-2-yl) benzenesulfonamide, N-(pyrimidine-2-yl) benzenesulfonamide, N-(3, 4-dimethyl pyrimidine-2-yl) benzenesulfonamide or N-(3, 4-dimethyl pyrimidine-2-yl) benzenesulfonamide; the preparation method comprises the following steps: preparing N-(5, 4-dimethylisoxazole-5-yl) benzenesulfonamide, N-(3-methoxypyrazine-2-yl) benzenesulfonamide, N-(6-methoxypyrimidine-4-yl) benzenesulfonamide, 3-amino-N-phenylbenzenesulfonamide, N-((4-aminophenyl) sulfonyl) benzamide, N-(5, 6-dimethyl-2, 4-dimethylisoxazole-5-yl) benzenesulfonamide, N-(4-aminophenyl) sulfonyl) benzamide, N 2, 6-dimethoxypyrimidine-4-yl) benzenesulfonamide, N-(6-chloropyridazine-3-yl) benzenesulfonamide and the like or disubstitution of any combination of the above substituent groups are selected. The derivative has a good inhibition effect on rice bacterial leaf streak, tobacco bacterial wilt, potato late blight and tobacco mosaic disease. The compound I-3 and kasugamycin show a synergistic effect in the process of preventing and treating the rice streak pathogen, and the purposes of pesticide reduction and synergism can be achieved. The plant growth regulator activity of part of the compounds is tested, and the compound I-3 is found to have good auxin activity and cytokinin activity.

The invention belongs to the technical field of pesticide preparation, and particularly discloses a preparation method of a biopesticide for preventing and treating rice diseases, which comprises the following steps: S1, adding allicin, an emulsifier and a synergist into a mixing device, mixing to prepare a primary emulsion, and heating the primary emulsion to 45-60 DEG C; s2, adding water and a pH regulator into the primary emulsion, uniformly stirring again to prepare a medium emulsion, and controlling the medium emulsion at 45-60 DEG C; and S3, adding kasugamycin into the intermediate emulsion, and uniformly stirring to obtain the final emulsion. S4, finally, adding the final emulsion into a filtering device for filtering, and filtering out impurities to prepare the biopesticide. The device further comprises a mixing device and a filtering device; the filtering device is arranged below the mixing device; the mixing device comprises a mixed material heating assembly, a stirring assembly and a lifting assembly; the stirring assembly is arranged in the middle of the mixing heating assembly, and the lifting assembly is arranged on the outer side of the mixing heating assembly.

The invention provides a kasugamycin solution, and a preparation method and application thereof, and the solution is mainly prepared from the following raw materials by mass: 2-10% of kasugamycin; 0.01% to 0.05% of chitosan oligosaccharide; 0.05% to 0.3% of glucan; 0.05% to 0.2% of a bacillus licheniformis metabolite; 0.1%-0.3% of potassium phosphite; 0.05%-0.15% of polyglutamic acid; the total percentage is 100%. According to the kasugamycin solution, through a multi-channel synergistic effect, effective components are efficiently utilized, the lasting period can be remarkably prolonged, and the kasugamycin solution has urgent and important significance in promoting development of an agricultural green prevention and control technology.

According to the stable kasugamycin technical, the stable kasugamycin technical and the stable kasugamycin technical concentrate and the stable kasugamycin composition, the mass ratio of kasugamycin or salt of kasugamycin to protein in the kasugamycin composition or the protein content or polysaccharide content in the kasugamycin composition is controlled, and the kasugamycin composition has better stability in the aspects of smell, color appearance and / or hygroscopicity and the like; therefore, the method has remarkable beneficial effects in storage, freight and terminal application, and in addition, key substances influencing the stability are controlled to guide production and manufacturing, so that cost control is facilitated.

This invention relates to a nano-suspension containing thiazolium zinc and kasugamycin, wherein the mass ratio of thiazolium zinc to kasugamycin in the suspension is 7:1, and the particle size D90 of the suspension is 0.40 μm to 0.80 μm. The nano-suspension is prepared by thoroughly mixing thiazolium zinc technical, kasugamycin technical, necessary suspending agents, and water, followed by sand milling. In the suspension containing thiazolium zinc and kasugamycin prepared by this invention, the decomposition rate of kasugamycin is lower, and it is suitable for maintaining a low decomposition rate for extended periods in harsh environments.

The application discloses a microbial source bactericidal composition containing Leuconostoc mesenteroides WZ-44 and kasugamycin and application thereof. The bactericidal composition takes Leuconostoc mesenteroides WZ-44 fermentation liquor (or fermentation sterile filtrate) and kasugamycin as main effective components, wherein the mass ratio of the Leuconostoc mesenteroides WZ-44 fermentation liquor (or fermentation sterile filtrate) to the kasugamycin is 4999:1-99:1, and is further preferably 1499:1-499:1. The bactericidal composition shows a synergistic effect within the above-mentioned ratio range, overcomes and delays drug resistance of pathogenic bacteria, has a good prevention and control effect on pear fire blight, a long effective period and low application cost, is obviously superior to a single agent in the prevention and control effect, and greatly reduces the use amount of the kasugamycin.

The invention relates to the technical field of pesticide bactericides, and discloses a composition containing meconazole and phenazino-1-carboxylic acid, and the composition is obtained by reasonably compounding meconazole and phenazino-1-carboxylic acid. The composition disclosed by the invention is applied to crops, the applied composition not only can be fully absorbed by the crops, but also can be used for preventing and controlling diseases of the crops through two action mechanisms at the same time, so that the composition has good synergistic and persistent effects, and the prevention and control effect of the composition is higher than that of a single substance; according to the composition, the dosage of chemical pesticides can be remarkably reduced, the residual quantity of the chemical pesticides on crops is reduced, the pollution to the environment is reduced, the generation of drug resistance of diseases can be effectively avoided, the action duration of the composition is prolonged, and the composition has a good prevention and treatment effect. The compound can be widely applied to the field of agricultural bactericides and has a wide application value.

The present invention relates to agrochemical combinations, compositions and methods for controlling phytopathogenic infestation. Particularly, the present invention relates to controlling phytopathogenic infestation using kasugamycin. Also, the present invention relates to combination or composition comprising kasugamycin and one or more insecticidal agents / fungicidal agents for controlling bacterial infestation or agent transmitting bacterial infestation and diseases caused thereby in a crop or a part thereof, particularly a cereal crop and methods of using the same.

The invention belongs to the technical field of food safety detection, and particularly relates to a kit and a method for detecting kasugamycin through visual fluorescence. The kit provided by the invention comprises a DT-Cu nano-enzyme dispersion liquid, a buffer solution, a hydrogen peroxide solution and a thiamine solution. The method comprises the following steps: mixing a to-be-detected solution with a DT-Cu nano-enzyme dispersion liquid to obtain a Y1 solution, mixing the Y1 solution with a buffer solution, a hydrogen peroxide solution and a thiamine solution, and carrying out a catalytic oxidation reaction to obtain a Y2 solution; and performing fluorescence detection or ultraviolet irradiation on the Y2 solution and a control solution, and realizing qualitative detection of kasugamycin in the to-be-detected solution according to a fluorescence spectrum obtained by comparing the Y2 solution and the control solution or fluorescence intensity of an ultraviolet irradiation picture. A fluorescence method is adopted for rapid detection, specificity is high, operation is easy, the result is reliable, the technical problem that kasugamycin cannot be rapidly detected is solved, and high practicability and wide applicability are achieved.

This invention relates to the field of kasugamycin production technology, specifically disclosing a kasugamycin fermentation culture medium and a kasugamycin fermentation method. The fermentation basal culture medium and the supplemental culture medium are composed of the following components by volume percentage: 5-8% soybean meal, 0.1-0.5% sodium glutamate, 0.26-0.5% potassium dihydrogen phosphate, 0.25-0.5% corn steep liquor, 7-9% soybean oil, and 1-3% maltodextrin. The supplemental culture medium consists of 0.5-1.6% soybean meal and 0.1-0.3% inositol. This invention, by optimizing the basal culture medium formula and combining it with the addition of soybean meal and inositol in the middle and late stages, effectively increases the fermentation potency of kasugamycin. Simultaneously, it avoids the problem of increased fermentation broth viscosity and impaired dissolved oxygen transfer caused by an unreasonable carbon-nitrogen ratio in traditional fermentation processes. It significantly reduces the viscosity of the fermentation broth, improves oxygen supply, and is beneficial for cell growth and the synthesis of secondary metabolites.

The invention discloses a bactericidal composition for preventing and treating gray mold and application thereof, and belongs to the technical field of pesticides. The effective components of the bactericidal composition disclosed by the invention are the flurobixafen and the zhongshengmycin, wherein the mass ratio of the flurobixafen to the zhongshengmycin is (2-9): 1. The Zhongshengmycin and the chlorine fluorine bixafen are compounded for preventing and treating the gray mold, so that the pesticide dosage is reduced during use, the prevention and treatment cost is reduced, the generation of pathogenic bacterium resistance is delayed, and the pollution to the environment is reduced.

The chitinase 3-like 1 (CHI3L1) inhibitor, specifically kasugamycin, provided by the present invention, suppresses the expression or activation of chitinase 3-like 1 (CHI3L1), thereby effectively preventing or treating infections with acid-fast bacteria, particularly non-tuberculous mycobacteria and various diseases caused by infection with acid-fast bacteria, particularly nontuberculous mycobacteria. In addition, by measuring the expression level of chitinase 3-like 1 (CHI3L1) protein, when the expression level is higher than that of a control group, it is possible to effectively predict infection with acid-fast bacteria, particularly non-tuberculous mycobacteria, the onset of diseases caused by infection with acid-fast bacteria, particularly non-tuberculous mycobacteria, or the prognosis of diseases related to infection with acid fast bacteria, particularly nontuberculous mycobacteria.

A fungicidal composition, the fungicidal composition comprising a component A, the component A comprising a cyclic ester peptide gold basidiosin A or a stereoisomer thereof; and a component B, wherein the component B comprises spring daily mycin or natamycin. A method of controlling or preventing a phytopathogenic disease or a phytopathogenic fungus on a plant or on propagation material thereof, the method comprising applying the composition to the plant, locus or propagation material thereof. The invention also relates to the use of the composition as a fungicide.

The present invention relates to a crystal form I of an agricultural antibiotic kasugamycin hydrochloride and a composition of the crystal form I and kasugamycin acetamide. The crystal form I shows good stability in a high-temperature, high-humidity, and illumination environment, and shows an unexpected plant disease prevention and treatment effect while better meeting the requirements of pesticides in production, processing, and transportation and storage.

The present invention discloses a compound antibacterial agent for flue-cured tobacco plant growth and its preparation method, belonging to the technical field of antibacterial agents. First of all, the compound antibacterial agent for flue-cured tobacco plant growth, calculated by weight percentage, comprises the following components: 0.5% - 2.0% of chlorophyllin iron(III) chelate, 0.05% - 0.1% of kasugamycin, 0.15% - 0.25% of dimethomorph, 6% - 8% of polyglycerol fatty acid ester, 4% - 5% of organosilicon surfactant, 2% - 4% of antifreeze, 10% of organic solvent, and the balance is pure water. The present invention first combines chlorophyllin iron(III) chelate with kasugamycin and dimethomorph, and realizes disease prevention and control through the "immune activation + targeted sterilization" double path. Through detection, the comprehensive control effect of the compound antibacterial agent on bacterial wilt and black shank diseases reaches 80.3% - 94.7%, which is significantly higher than that of the single-agent control group (control effect < 55%), proving the synergistic effect of chlorophyllin iron(III) chelate and the bactericide.

The present invention belongs to the field of nano-pesticides, and particularly relates to a pesticide variety which is insoluble in water and a solvent, and the preparation of a suspended dispersion having a particle size of 100 nm or less. The zinc thiazole / kasugamycin suspended nano-dispersion at the scale of under 100 nm of the present invention is formed by means of diluting two or three components with water and mixing same.

The invention belongs to the field of agricultural chemistry, and particularly relates to a biological source bactericide and application thereof. The active ingredients of the bactericidal composition comprise zhongshengmycin and magnolol, and the weight ratio of zhongshengmycin to magnolol is (1: 20)-(5: 1). The bactericide provided by the invention belongs to a biological source bactericide and is environment-friendly, and the combination of the active components has an obvious synergistic effect, so that the dosage of the bactericide can be reduced, and the generation of drug resistance of diseases can be delayed.