249 results about "Bacteriocidal Agents" patented technology

To provide a novel pest control agent composition, particularly a bactericidal composition.SOLUTION: A bactericidal or bacteriostatic composition comprising an active ingredient A selected from pyrazole compounds or salts thereof represented by formula (I): [G represents G-1; G1 represents C1-C6 haloalkyl or the like; T represents an oxygen atom or the like; RX represents C1-C6 alkyl or the like; RY represents a hydrogen atom or the like; R1 represents a hydrogen atom or the like; R2 represents a hydrogen atom or the like; R3 represents a hydrogen atom or the like; Ra represents a hydrogen atom or the like; Z represents Z-1 or the like; Z1 represents C1-C6 alkyl or the like; m5 and n5 each represent an integer of 0, 1, 2, 3, 4, or 5; and p represents an integer of 0 or 1] and an active ingredient B selected from known bactericidal or bacteriostatic compounds.SELECTED DRAWING: None

The invention discloses a method for detecting drug resistance of botrytis cinerea to succinate dehydrogenase (SDHI) bactericides. On the basis of an RPA-CRISPR / Cas12a system, a specific primer pair amplification target fragment and crRNA for activating Cas12a trans-cleavage activity are designed aiming at key mutation sites related to drug resistance in a bactericide action target SdhB gene, so that fluorescent light visible to naked eyes can be generated only when a resistant strain sequence is matched with the crRNA, and the fluorescent light is opposite to the fluorescent light generated when a sensitive strain sequence is matched with the crRNA. The method provided by the invention overcomes the dependence on laboratories and large instruments in the traditional drug resistance detection method, provides key technical support for accurate prevention and control and drug resistance management of grape gray mold, and provides direct drug use basis for scientific prevention and control in the field.

The invention belongs to the technical field of agricultural microorganisms, and discloses a bacillus flexus strain BJ699 and application thereof in strawberry production. Specifically, the invention provides a novel bacillus flexus strain BJ699, and the preservation number of the strain BJ699 in the China Center for Type Culture Collection is CCTCC (China Center for Type Culture Collection) NO: M20252013. The invention also provides a microbial agent containing the strain BJ699 as an active component and application of the strain BJ699 in preparation of a microbial agent for prevention and control of strawberry root rot pathogenic bacteria and / or degradation of pyraclostrobin. The new strain or the microbial agent containing the strain comes from the natural environment, has no cross resistance to existing bactericides and insecticides, has the advantages of high efficiency, low toxicity, no environmental pollution, low possibility of drug resistance generation and the like, and has a wide application prospect.

The invention relates to the technical field of sewage treatment, in particular to a preparation method of a degradable bactericide for an oil field. According to the invention, a hydroxypropyl guanidine gum-polycaprolactone-ethylenediamine fragment copolymer is taken as a carrier, a methylisothiazolinone quaternary ammonium salt (Q-MIT) bactericide is loaded, and the degradable bactericide for the oil field is obtained by cooperating with a dodecyl ethyl sulfide (TC-SE) bactericide and combining with sodium polyaspartate. A carrier forms a hydrogen bond with a polar group on the surface of a biological membrane through a hydroxypropyl guanidine gum main chain to realize targeted anchoring, a polycaprolactone branched chain encapsulates Q-MIT through a hydrophobic effect, primary amino groups of ethylenediamine are introduced to form a pH sensitive Schiff base bond with Q-MIT, and the primary amino groups and adipic dihydrazide form a thermal response hydrazide bond to construct a dual dynamic covalent bond, so that controlled release of Q-MIT is realized, and the biomembrane is prepared. And moreover, the components of the whole system are connected through degradable chemical bonds, so that the environmental protection property and sustainability of oil field operation are guaranteed.

The invention relates to a synergistic composition for preventing and treating celery root rot. The tannic acid and fludioxonil in the synergistic composition disclosed by the invention show a relatively good synergistic effect in a compounding mass ratio range of (1: 50)-(50: 1). According to the synergistic composition disclosed by the invention, tannic acid with weak bacteriostatic activity on celery root rot and fludioxonil with excellent bacteriostatic activity are compounded for use, so that a remarkable synergistic effect is achieved, the prevention and treatment effect is far higher than that of a single agent, and the synergistic effect is achieved by reducing pesticide. Besides, according to the synergistic composition disclosed by the invention, the plant source tannic acid and the chemical bactericide fludioxonil are compounded for use, and the use amount of chemical agents is reduced, so that the resistance risk of the chemical bactericide is reduced, pesticide residues and ecological environment pollution are reduced, and the synergistic composition has a good application prospect.

According to the suspending agent containing the pydiflumetofen and the meconazole, provided by the invention, the defects of a traditional single bactericide are overcome, and the control effect on various plant diseases is improved. According to the suspending agent disclosed by the invention, a natural biological source substance chitosan oligosaccharide is introduced as a thickening agent, so that the prevention and treatment effect of the agent on the rice sheath blight disease can be improved unexpectedly.

The invention relates to the technical field of agricultural plant disease control, and particularly discloses a biological and chemical compound bactericide and application thereof. The biological and chemical compound bactericide comprises a bacterial solution of a biocontrol strain bacillus velezensis LHN1 and a chemical bactericide, the biocontrol strain bacillus velezensis LHN1 is preserved in Guangdong Microbial Culture Collection Center, and the preservation number is GDMCC No: 63550; the chemical bactericide is selected from at least one of prochloraz, pyraclostrobin or tebuconazole; in the compound bactericide, the volume ratio of the LHN1 bacterial liquid to the chemical bactericide is (1: 4)-(4: 1). Through the synergistic effect of biological prevention and control and chemical prevention and control, the problems that a single chemical bactericide pollutes the environment and the single biological prevention and control effect is unstable are solved, the prevention effect in a pot experiment reaches up to 83.99%, meanwhile, the dosage of chemical agents is reduced by 30%-50%, and the method has the advantages of being efficient, low in toxicity and low in cost and is suitable for root rot prevention and control in large-scale planting of rhizoma polygonati.

The invention relates to the technical field of pesticides, in particular to a hydrazide derivative containing a 3, 4-dihydroisoquinoline structure, a preparation method and application. The hydrazide derivative containing the 3, 4-dihydroisoquinoline structure is a compound as shown in a formula (I), or a stereoisomer, a tautomer, an isotope derivative and a pesticide acceptable salt thereof. The hydrazide derivative containing the 3, 4-dihydroisoquinoline structure has broad-spectrum inhibitory activity on phytopathogens such as plant pathogenic fungi, especially has excellent inhibitory activity on basidiomycota and ascomycomycota pathogenic fungi such as gaeumannomyces graminis, physalospora piricola, sclerotinia sclerotiorum, botrytis cinerea and rhizoctonia solani, and has broad-spectrum inhibitory activity. The bactericide is expected to be developed into a novel green bactericide which is efficient, safe, economical and environment-friendly.

The application discloses application of 5,8,11-eicosatrienoic acid in prevention and treatment of plant fungal diseases and belongs to the field of pesticide chemistry. The 5,8,11-eicosatrienoic acid mainly prevents and treats diseases caused by the oomycete class capsicum phytophthora, the compound is a long-chain unsaturated fatty acid, has an antifungal disease effect and can be used as a fungicide to prevent and treat plant diseases. The compound can effectively prevent pathogenic bacteria from invading plants by inhibiting mycelium growth, enhancing cell membrane permeability and interfering with the spore sac release process, and is further used for preventing and treating huge plant fungal diseases. Biological tests show that the compound has a significant concentration-dependent inhibitory effect on the mycelium growth of the capsicum phytophthora, and the half effective inhibitory concentration (EC50) is 60.2 µg / mL. At a concentration of 200 µg / mL, the inhibition rate is more than 83%, the 5,8,11-eicosatrienoic acid can effectively inhibit the release of the capsicum phytophthora spore sac, and the EC50 is 156.3 µg / mL. At a concentration of 200 µg / mL, the inhibition rate is morethan 77%.

The invention relates to the field of agricultural bactericides, in particular to a suspending agent containing fenaminstrobin and validamycin A and application of the suspending agent. The bactericidal composition comprises a suspending agent containing fenaminstrobin and validamycin A, an active component, a stabilizer, an auxiliary agent and water, the active component accounts for 1-70% of the mass of the preparation, and the stabilizer accounts for 0.1-10% of the mass of the preparation; wherein the active ingredients are fenaminstrobin and validamycin A, and the stabilizer is meglumine (N-methyl-D-glucosamine). The suspending agent prepared by the technical scheme of the invention effectively inhibits the increase of the particle size of a sample in the thermal storage process of a preparation, effectively improves the suspension rate of fenaminstrobin after the thermal storage of the preparation, improves the utilization rate of a pesticide, and ensures the normal exertion of the efficacy of the pesticide at the same time. Meanwhile, the quality of the active components of the stabilizer-containing bactericide is stable within the shelf life, the addition of the stabilizer does not cause the decomposition of the active components, and the preparation does not have obvious physical or chemical change.

A living paint comprises a living photosynthetic microorganism, binder, growth medium, and water. The microorganism may comprise algae, cyanobacteria, or lichens. The binder may be composed of primary

The present application relates to a kind of bactericidal liquid agent based on cuprous hydroxide, and its preparation method and use method, with the suspension of cuprous hydroxide as bactericidal liquid agent, can effectively prevent and cure the disease caused by a variety of oomycetes, fungi and / or bacteria, wherein the suspension of cuprous hydroxide is obtained by stirring in water by the solution state cuprous chloride coordination compound decomposition.This bactericidal liquid agent of the present application can be far lower than the existing copper ion bactericide while the single copper dosage is lower, and the prevention and cure range of disease is wider.This not only solves the risk of heavy metal excess residue caused by the existing copper preparation, but also avoids the problem of needing to use multiple bactericides simultaneously to prevent and cure one or more diseases.The bactericidal liquid agent of the present application has important significance for plant disease prevention and cure, and has great application potential in agricultural market.

The invention discloses an antibacterial peptide induced by sulfate reducing bacteria and application of the antibacterial peptide, and belongs to the technical field of marine corrosion protection. The amino acid sequence of the SRB-induced antibacterial peptide is VAHKRLVVGTR, and the SRB-induced antibacterial peptide has efficient antibacterial activity on corrosive bacteria such as SRB and has the advantages of being environmentally friendly and not prone to inducing the bacteria to generate drug resistance, and the problems that an existing antibacterial peptide is insufficient in corrosive bacteria specificity, poor in environmental stability and the like are solved; meanwhile, peptide chains are short, synthesis is easy, and the production cost is low; the compound corrosion inhibition bactericide formed by combining the compound with a chemical bactericide can significantly improve the antibacterial and antiseptic effects, saves the dosage of the chemical bactericide, effectively solves the problems of bacterial drug resistance, high cost, environmental pollution and other pain points caused by abuse of the existing bactericide, and is suitable for the fields of marine microbial corrosion protection and the like.

The invention relates to antibacterial and mildew-proof leather sponge with silver ions, which comprises the following components in parts by weight: 60-80 parts of ethylene vinyl acetate and 1-5 parts of foaming agent. The leather comprises the following components in parts by weight: 40-60 parts of polyester modified MD I, 10-20 parts of a silver ion antibacterial agent, 1-3 parts of a plasticizer, 15-25 parts of a bactericide, 1-2 parts of a mildew preventive, 1-3 parts of sponge glue, 3-5 parts of a cross-linking agent, 0.5-0.6 part of a catalyst, 40-50 parts of a leather body, 1-2 parts of leather softening enzyme and 1-2 parts of a leather adhesive. According to the antibacterial and mildew-proof leather sponge with the silver ions and the preparation method, when sponge leather is prepared, due to the excellent antibacterial performance of the silver ions, the silver ions are in contact reaction with cells, inherent components of bacteria are damaged or functional obstacles are generated, and bacterial death is caused, meanwhile, the leather sponge can be prevented from mildewing in cooperation with the mildew preventive, and the antibacterial and mildew-proof effects are achieved. The leather sponge has the antibacterial and mildew-proof functions, and the use experience of a user is improved.

The invention discloses a bacteriophage capable of efficiently splitting Pseudomonas ongdamura and a composition and application thereof, the bacteriophage is Pseudomonas ongdamura bacteriophage PL1P1, the preservation number is CCTCCM20251191, the Pseudomonas ongdamura bacteriophage PL1P1 is a virulent bacteriophage separated from the nature, and the Pseudomonas ongdamura bacteriophage PL1P1 has relatively high tolerance to ultraviolet rays and pH, and can be used for efficiently splitting Pseudomonas ongdamura and Pseudomonas ongdamura and Pseudomonas ongdamura. The bacteriophage is suitable for different prevention and treatment environments and can achieve a good fresh-keeping effect on chilled meat, DNA of the bacteriophage cannot encode protein possibly causing potential health risks, the possibility of carrying lysogenic genes does not exist, the bacteriophage has high affinity and splitting capacity, the titer of 10 < 10 > PFU / mL or above can be achieved within 24 h of culture, and the bacteriophage has good application prospects. The Pseudomonas longdamura phage PL1P1 can specifically partially or completely inactivate Pseudomonas longdamura, can complete mass proliferation only by using a small amount of initial phage, and provides a high-quality phage strain source for industrial production of phage bactericides.

The compound shown in the formula (I) has good activity to various pathogenic bacteria in agriculture or other fields. Moreover, the compound can obtain good prevention and treatment effect at a very low dose, and thus can be used for preparing a fungicide. In addition, the compound has simple preparation steps and high yield, and thus has good application prospect.

The invention belongs to the technical field of marine corrosion and protection, and discloses an antibacterial peptide for marine corrosion prevention and fouling prevention and application of the antibacterial peptide, the sequence of the antibacterial peptide is H-NIle-NVal-NLys-NLU-NPhe-NLU-NTyr-NArg-NSer-NTrp-NLU-NHis-NLU-NLU-NIle-NH2, the antibacterial and preservative effects of common corrosion inhibition bactericides such as quaternary ammonium salts, organic guanidines and aldehydes can be effectively enhanced, and the antibacterial peptide can be applied to marine corrosion prevention and fouling prevention. The generation of a corrosive biological membrane and the microbial corrosion rate can be effectively inhibited, the dosage of a bactericide can be reduced by 60% or above, and continuous antibacterial and anticorrosion for 30 days can be realized.

The use of an LtPCL6 protein and a gene encoding same in regulating pathogenicity, mycelial growth, and stress resistance of Lasiodiplodia theobromae. The gene encoding LtPCL6 protein is derived from Lasiodiplodia theobromae, and a knockout mutant is obtained by constructing a knockout fragment of a Lasiodiplodia theobromae LtPCL6 gene, and introducing same into a Lasiodiplodia theobromae protoplast. Experiments indicate that the LtPCL6 gene has an effect in the growth, cell wall and cell membrane integrity, and stress resistance of Lasiodiplodia theobromae, and significantly reduces the pathogenicity of the Lasiodiplodia theobromae with regard to a host. Therefore, the LtPCL6, serving as a fungicide target and a key protein of a pathogenic mechanism of diseases, can be used for developing agents for diseases caused by Lasiodiplodia theobromae infection and breeding new resistant varieties, and has broad application prospects in the control of plant pathogenic fungal diseases.

The invention belongs to the technical field of pesticides, and relates to 11 bactericide compositions for mainly preventing and treating crop diseases caused by pyricularia oryzae and colletotrichum gloeosporioides. The compound YJY-22 provided by the invention is novel in structure and unique in action mode, and has no cross resistance with isoprothiolane, fenoxanil, pyraclostrobin, tricyclazole, azoxystrobin, mancozeb, captan, difenoconazole, prochloraz, chlorothalonil and tebuconazole. As the action mechanism of the compound YJY-22 is different from that of the medicament, and the compound YJY-22 and the medicament have no cross resistance, the compound YJY-22 and the medicament are compounded, so that the sterilization range can be expanded, the sterilization effect can be enhanced, the drug resistance of phytopathogen can be delayed, the safety to crops is good, the prevention and control spectrum is expanded, and the requirements of pesticide reduction and synergism are met.

The present invention relates to a class of (R)-2-aryl-4,5-dihydrothiazole-4-carboxylic acid derivatives containing dihydrazide having fungicidal activity as shown in general formula (I), as well as preparation methods and applications thereof. A pesticide molecule design method of splicing active fragments is used to connect differently substituted (R)-2-aryl-4,5-dihydrothiazole-4-carboxylic acids with differently substituted benzoylhydrazides, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and R 10 As defined in the specification. The technical effect of the present invention is: a class of (R)-2-aryl-4,5-dihydrothiazole-4-carboxylic acid derivatives containing dihydrazide with broad-spectrum fungicidal activity has been discovered, which is a fungicide with broad application prospects.

The present application relates to the technical field of pesticides, and discloses a chromene aryl hydrazide derivative, a preparation method and application thereof, a structural general formula of the chromene aryl hyydrazide derivative is as formula (I); the preparation method is as follows: taking p-hydroxybenzaldehyde as raw material, and obtaining the chromene aryl hydrazide compound through substitution reaction, cyclization reaction, oxidation reaction, acylation reaction and hydrazinolysis reaction. The chromene aryl hydrazide compound is used for preparing an agricultural bacteriostatic agent. The present application combines aryl hydrazine and chromene skeleton by using the pharmacophore splicing principle in medicinal chemistry, and designs and synthesizes a series of chromene aryl hydrazide compounds. The bacteriostatic activity test result shows that the compounds have excellent bacteriostatic activity, and can be used as active ingredients for preparing a plant pathogenic fungus fungicide.

The application discloses a method for treating hydrogen sulfide in oil wells, which comprises the following steps: (1) screening of test oil reservoir; (2) preparation of specific virulent SRB phage stock solution; (3) enrichment of specific virulent SRB phage; (4) determination of optimal titer of specific virulent SRB phage solution; (5) selection of phage fusion bactericide; (6) determination of optimal intervention point of bactericide; (7) field test and effect evaluation. The application has the following advantages: (1) wide adaptability, simple method and good operability; (2) strong pertinence; (3) phage bactericidal action can prevent the generation of bacterial drug resistance and can prolong the use time of bactericide; (4) the cost is reduced by more than 50% compared with the prior art; meanwhile, the damage of bactericide toxicity to the formation is reduced, and the method is economic and environment-friendly.

The invention discloses a quinolinic acid diaryl ether derivative, a preparation method and application thereof and a bacteriostatic agent or bactericide, relates to the technical field of medicinal chemistry, solves the problems that existing pesticides are high in toxicity and not environmentally friendly, easily cause drug resistance of pathogenic bacteria and possibly have negative effects on the environment and an ecological system, can efficiently prevent and treat fungal diseases of plants, and also can effectively prevent and treat the pathogenic bacteria of the plants. The quinolinic acid diarylether derivative has the advantages that the quinolinic acid diarylether derivative has excellent inhibition activity on agricultural fungi such as rhizoctonia solani, sclerotinia sclerotiorum, botrytis cinerea, fusarium graminearum and fusarium pseudograminearum, and the quinolinic acid diarylether derivative has the characteristics of simple synthesis process, cheap and easily available raw materials, good control effect, wide bactericidal spectrum and the like.

The application discloses a kind of two-component fungicide containing fluoximide, effective component includes fluoximide and propiconazole, and the weight ratio of fluoximide and propiconazole is 1 :(0.2-3).The application has good control effect on banana leaf spot disease, and is safe to banana, can delay the process of drug resistance of drug resistance;And the combination of aryl phenol polyoxyethylene ether and fatty alcohol polyoxyethylene ether is used as emulsifying agent, and the prepared pesticide microemulsion has good stability and short foaming time.Fluoximide and propiconazole mixed preparation have good synergistic effect, can reduce the amount of drug, delay and control the drug resistance of pathogenic bacteria, and also make the mixed preparation have protection, treatment and internal absorption, realize the purpose of taking long and short, complementary advantages, expand the control spectrum and use range.

This present invention is directed to antimicrobial fabric care compositions that provide detersive benefits such as stain and soil removal and aesthetic benefits like softening, wrinkle-reduction and color-protection and when used discretely or synergistically during the laundry program reduce the risk of infections and promote health and hygiene by providing dose-dependent antimicrobial activities such as sanitizing, disinfecting and removing malodors from fabrics, and imparting 24-48 hour antimicrobial-durability into fabrics, and deactivating biofilms inside the washing machine and preventing biofilm formation inside the washing machine to prevent recontamination of fabrics. The compositions are well-suited for use in domestic, commercial and on-premise-laundry-operations such as healthcare facilities, hotels, cruise ships, and the like. Methods for discrete and synergistic uses to simultaneously treat fabrics and the internal surfaces of the washing machine are also disclosed.

The invention relates to an antibacterial peptide, a bacteriostatic bactericide composed of the antibacterial peptide and application of the antibacterial peptide and the bacteriostatic bactericide. The antibacterial peptide has any one of the following amino acid sequences: 1) an amino acid sequence as shown in SEQ ID No.1 or SEQ ID No.2; 2) an amino acid sequence which is obtained by carrying out substitution, deletion and / or addition modification on SEQ ID No.1 or SEQ ID No.2 by 1-3 amino acids and has the same or similar functions as the SEQ ID No.1 or SEQ ID No.2; and 3) an amino acid sequence obtained by cyclizing the SEQ ID No.1 or the SEQ ID No.2 or modifying N, C tail ends and / or side chains of the SEQ ID No.1 or the SEQ ID No.2. The invention also discloses an application of the antibacterial peptide in preparation of a bacteriostatic bactericide, and the bacteriostatic bactericide composed of the antibacterial peptide. The antibacterial peptide disclosed by the invention can kill various bacteria in a short time, can inhibit the formation of bacterial biofilms and remove mature biofilms, has extremely strong broad-spectrum antibacterial performance, is relatively low in hemolytic activity and high in safety, can be applied to preparation of antibacterial and bactericidal products, and has a relatively great application prospect in preparation of antibacterial and bactericidal agents.

The invention relates to a fungicide composition for preventing and treating peanut root rot as well as preparation and application of the fungicide composition. The invention aims to solve the technical problems of unstable field control effect, high chemical pesticide residue and high drug resistance risk of biological control in peanut root rot control. Bacillus velezensis YJ02 with good biocompatibility is compounded with azoxystrobin (a biological fungicide generates antibacterial substances and induces plant defensive enzymes, and a chemical fungicide is combined to rapidly inhibit respiration of pathogenic bacteria) to prevent and treat peanut root rot; the technical effects that the efficient synergistic control effect (for example, the control effect reaches up to 86.79%) is achieved, the application amount of chemical pesticides is reduced (for example, the dosage of azoxystrobin is only 9.82% of the conventional dosage), the drug resistance risk of pathogenic bacteria is effectively reduced, the morbidity and disease index are reduced, and environment friendliness is achieved are achieved, and high economic benefits and social benefits are achieved.

The invention discloses a water control type workover fluid and a preparation method thereof. The water control type workover fluid is prepared from the following components in parts by weight: 2 parts of a clay stabilizer, 0.2-1 part of a high-temperature chelating agent, 0.5-1 part of a corrosion inhibition bactericide, 1-2 parts of a waterproof locking agent, 5 parts of a phase change agent and 100 parts of filtered seawater. The method comprises the following steps: filtering the filtered seawater until suspended particles are less than 30 microns in standard value, sequentially adding a clay stabilizer, a high-temperature chelating agent, a corrosion inhibition bactericide, a water blocking prevention agent and a phase change agent, and uniformly stirring to obtain the water control type workover fluid. After the workover fluid enters a reservoir, the oil phase starting pressure can be reduced, the oil-water interfacial tension can be reduced, the effect of inhibiting water content rising after well workover is achieved, the workover fluid can be matched with different field operation types, and the recovery period of an oil well can be shortened.

The invention relates to the technical field of detergent compositions, and discloses a preparation method of a seaweed extract composite disinfecting and killing detergent composition, which comprises the following steps: under temperature-controlled stirring, mixing alkyl glycoside and a quaternary ammonium salt cationic bactericide according to a specific molar ratio and a free water content of less than 55% to construct a high-viscosity water-deficient lamellar liquid crystal shielding phase; the shielding phase is immersed and injected into a seaweed extract substrate solution, shearing dispersion is performed at a specific rate to obtain the composition, a metastable-state water-deficient layered liquid crystal structure is constructed, the cationic bactericide and the anionic seaweed extract are physically isolated through the steric hindrance effect at the mixing moment, flocculation caused by charge confrontation is effectively blocked, and the stability of the composition is improved. Thermodynamically stable coexistence and functional compatibility of the two in a single water phase system are realized, and the bactericidal activity can be released during dilution use.