Formula composition and medicinal preparation with effects of increasing bone density and treating bone joint pain, preparation method of medicinal preparation and application of formula composition

A technology for increasing bone density and pharmaceutical preparations, applied in the directions of medical preparations containing active ingredients, food preparation, and drug combinations, etc. The effect of treating joint pain

Inactive Publication Date: 2014-01-22
北京一品堂医药科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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  • Formula composition and medicinal preparation with effects of increasing bone density and treating bone joint pain, preparation method of medicinal preparation and application of formula composition
  • Formula composition and medicinal preparation with effects of increasing bone density and treating bone joint pain, preparation method of medicinal preparation and application of formula composition
  • Formula composition and medicinal preparation with effects of increasing bone density and treating bone joint pain, preparation method of medicinal preparation and application of formula composition

Examples

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Embodiment 1

[0028] This embodiment provides a formula composition with the effects of increasing bone density and treating bone and joint pain, which can increase human bone density, prevent osteoporosis, and treat bone and joint pain. The formulation composition of the present embodiment is made up of the raw material of following weight portion:

[0029] D-glucosamine sulfate potassium salt 60-90 parts, calcium carbonate 35-65 parts, bone collagen 10-40 parts, psoraleae extract 10-25 parts, casein phosphopeptide 2-8 parts.

[0030] Among them, D-glucosamine sulfate potassium salt, also known as glucosamine sulfate potassium salt, the English name is "N-Sulfo-glucosamine potassium salt", we found in the study that glucosamine and chitosan oligosaccharides have a strong effect on bone turnover It has obvious inhibitory effect, can improve the ability of bone reconstruction, and has obvious antagonism effect on osteoporosis caused by ovariectomy.

[0031] In the comparative experiments of...

Embodiment 2

[0044] Embodiment 2 Provides a preferred formulation composition with the effect of increasing bone density and treating bone and joint pain on the basis of Embodiment 1, which consists of the following raw materials in parts by weight: 75 parts of D-glucosamine sulfate potassium salt, calcium carbonate 50 parts, collagen 25 parts, psoraleae extract 15 parts, casein phosphopeptide 4 parts.

[0045] In a preferred embodiment, the psoralen extract contains psoralen greater than or equal to 1% by weight.

[0046] The formulation composition described in this example can be prepared by mixing various raw materials.

[0047] The formula composition with the effect of increasing bone density can be taken orally after being prepared as a pharmaceutical preparation, and the recommended dosage for human body is 4g / person / day.

[0048] In this example, D-glucosamine sulfate potassium salt, calcium carbonate, collagen, psoraleae extract and casein phosphopeptide are used together in the...

Embodiment 3

[0050] Embodiment 3 provides a pharmaceutical preparation based on the formulation composition described in Embodiment 1, that is, the formulation composition is composed of the following raw materials in parts by weight:

[0051] D-glucosamine sulfate potassium salt 60-90 parts, calcium carbonate 35-65 parts, bone collagen 10-40 parts, psoraleae extract 10-25 parts, casein phosphopeptide 2-8 parts.

[0052] The pharmaceutical preparation of this embodiment is composed of the raw materials of the above formula composition and solid pharmaceutical auxiliary materials; the weight of the solid pharmaceutical auxiliary materials does not exceed 25% of the weight of the pharmaceutical preparation.

[0053] Specifically, the pharmaceutical preparation of this example uses the formula composition with the effect of increasing bone density described in Example 1 as a raw material, combined with solid pharmaceutical excipients to form a solid form of pharmaceutical preparation, which is...

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Abstract

The invention relates to the field of medicines and health care food, and particularly relates to a formula composition and a medicinal preparation with effects of increasing bone density and treating bone joint pain, a preparation method of the medicinal preparation and an application of the formula composition. The formula composition comprises N-sulfo-glucosamine potassium salt, calcium carbonate, collagen, fructus psoraleae extractive, and casein phosphopeptides. The formula composition can be prepared into various dosage forms to be used as medicines or health care food. The formula composition and the medicinal preparation thereof can effectively increase bone cell proliferation and the bone density, prevent various kinds of discomfort caused by bone loss and relieve bone joint pain, and have no toxic or side effects.

Description

technical field [0001] The present invention relates to the field of medicine and health food, in particular to a formulation composition, a pharmaceutical preparation, a preparation method and its use with the effects of increasing bone density and treating bone and joint pain, the formulation composition and pharmaceutical preparation of the present invention and according to the present invention The product prepared by the preparation method can be prepared as medicine or health food. Background technique [0002] Osteoporosis is a systemic bone disease characterized by decreased bone mass and destruction of bone microstructure, manifested by increased bone fragility, which in turn leads to a greatly increased risk of fracture, even with minor or no trauma fractures are also prone to occur. Osteoporosis is a multifactorial chronic disease. Before the fracture occurs, there are usually no special clinical manifestations. With the increase of the elderly population in o...

Claims

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Application Information

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IPC IPC(8): A61K38/39A23L1/29A61P19/10A61P19/02A61K38/02A61K36/487A61K33/10A61K31/7008A23L33/00
Inventor 贾银良
Owner 北京一品堂医药科技有限公司
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