The invention discloses a novel Chinese herbal medicine tobacco sheet and a preparation method thereof. The method comprises steps as follows: tobacco stems, tobacco powder, milkvetch roots, mulberry bark, pueraria roots, liquorice roots, ginkgo leaves, mulberry leaves and eucommia leaves are selected, washed clean and placed together to be cooked, and insoluble solids and a mixed solution are obtained; the insoluble solids are ground and evenly mixed with non-tobacco plant fiber pulp and water, and final pulp is obtained; papermaking, long-net water filtration, vacuum dehydration, squeezing and drying are performed on the final pulp, and a shaped tobacco sheet is obtained; a seasoning flavor is added to the mixed solution, the mixture is evenly mixed and then sprayed onto the tobacco sheet, the tobacco sheet is dried and sliced, and then the Chinese herbal medicine tobacco sheet is obtained. According to the novel Chinese herbal medicine tobacco sheet, the preparation process is simple and easy to implement, utilization rates of raw materials are high, and tar and harm can be reduced effectively; the finished product is mellow in taste, soft in smoke, little in miscellaneous gas and capable of regulating blood lipids, promoting blood circulation, eliminating blood stasis, clearing away heat and toxic materials, tonifying livers and kidneys, relieving coughs and asthma, enhancing human immunity and inhibiting human cardiovascular and cerebrovascular diseases and respiratory tract diseases.