100 results about "Propiophenone" patented technology

The present invention relates to hyaluronic acid ester derivatives, whose carboxylic groups are partially esterified with hydroxy groups of propiophenone derivatives, to the hydrogel materials consisting of the said hyaluronic acid ester derivatives, to their preparation process by photocuring of the hyaluronic acid ester derivatives, and their use in the biomedical, sanitary and surgical fields, and in the medical field as controlled release systems for drugs.

A propiophenone derivative of the formula (I): wherein OX is a hydroxy group which may optionally be protected, Y is a lower alkyl group, and Z is a beta -D-glucopyranosyl group wherein one or more hydroxy groups may optionally be protected, or a pharmaceutically acceptable salt thereof. Said compounds have excellent hypoglycemic activity so that they are useful in the prophylaxis or treatment of diabetes.

The invention discloses a method for preparing polymerizable photoinitiators. The polymerizable photoinitiators are prepared from methacrylic acid and 2-hydroxyl-4'-(2'-hydroxyethoxy)-2-methyl propiophenone by the aid of direct esterification processes. The use quantity of polymerization inhibitors in a reaction system accounts for 0.01%-0.5% of the mass of the methacrylic acid, the use quantity of methane sulfonic acid which is a catalyst accounts for 0.1%-2% of the mass of the methacrylic acid, and a molar proportion of the methacrylic acid to the 2-hydroxyl-4'-(2'-hydroxyethoxy)-2-methyl propiophenone is 1:1-1.2. Each polymerization inhibitor is methoxyphenol or hydroquinone or 2-tertiary butylhydroquinone, and a solvent is toluene or dimethylformamide or tetrahydrofuran. The method has the advantages that the polymerizable photoinitiators are excellent in compatibility with monomers and resin in photo-curing systems fragments obtained after the polymerizable photoinitiators are subjected to illumination pyrolysis are low in migration rate in cured films and are anti-yellowing, excellent initiation effects can be realized, and the method can be applied to the field of photo-cured coating, printing ink, adhesive and the like; the method for synthesizing the polymerizable photoinitiators is low in cost, processes for preparing the polymerizable photoinitiators are simple and convenient, and obvious application effects can be realized.

The invention relates to a concentrated multifunctional detergent. A formula of the concentrated multifunctional detergent contains the following ingredients in parts by weight: 2-8.5 parts of fatty alcohol-polyoxyethylene ether, 1-10 parts of sodium sec-alkyl sulfonate, 5-15 parts of alkyl glycoside, 10-30 parts of limonene, 5-10 parts of polyethylene glycol, 1-3 parts of radix astragali-polygonatum sibiricum extract, 2-5 parts of aloe gel, 0.5-2 parts of citric acid, 0.1-1 part of flavoring essence and 5-15 parts of water. The multifunctional detergent provided by the invention can be applied to various surfaces of metal, plastics, glass, stone, ceramics and the like and can be used for cleaning various blots such as oil stains, dust, printing ink, lipsticks, fruit juice, coffee, bloodstains, ball-point pen ink and marking pen ink. The multifunctional detergent is prepared from natural-derived raw materials, is free of heavy metals, is free of phosphorus and is free of toxic solvents such as benzene and acetone, thereby not polluting environment. Skin care ingredients are added, so that the multifunctional detergent does not injure hands and does not damage cleaned objects. A concentrate formula is adopted, so that transportation and storage are facilitated.

The invention belongs to the technical field of super-molecular chemistry and particularly relates to small molecule peptide-based cholesteric organic gel molecules and a preparation method thereof. The cholesteric organic gel molecules can form gel in an organic solvent and the formed gel has thermal stability and water stability and can respond to ultrasound for realizing transformation of ultrasonically-induced gel into gel. The organic gel molecule comprises 1) an anhydride naphthalene part serving as a luminophor, 2) a middle small peptide serving as a functional group for forming intermolecular hydrogen bonds and 3) a sterides part which has biocompatibility and serves as a gelation factor and a hydrophobic group. The molecule can form high-quality gel which has rich micro-nanoscale macro morphologies, such as nuclear shells, solid balls, defect balls, nanofiber, micro-fiber and the like, and has regular shape and high repeatability in nearly ten organic solvents including acetonitrile, ethanol, benzene, toluene, acetone and the like through a sol-gel process. The organic fluorescent gel has a certain application value in the aspects of nano material preparation, medicinal carrier transportation, biological marking and the like.

The invention relates to compositions comprising a hydrogel matrix, where the matrix comprises poly(ethylene glycol) dimethyacrylate (PEGDMA), an acrylate, such as methacrylic acid (M) and methyl methacrylate (MMA), as well as 2-hydroxy-2 methyl propiophenone (HMPP).

The invention provides a method for asymmetrically catalyzing and synthesizing (R)-(+)-3-chlorine-phenylpropanol. The method is implemented as follows: metal hydroboron is taken as a reducing agent and organic acid is taken as an accessory ingredient to asymmetrically catalyze and reduce 3-chlorine-propiophenone; spiroborate and hydroboron are mixed by a tetrahydrofuran solvent, a certain quantity of organic acid is added and stirred until mixed solution is clear and transparent, tetrahydrofuran solution of the 3-chlorine-propiophenone is dropped slowly and stirred to reaction at the 50 degrees below zero to 30 DEG C, reaction liquid is purified to obtain the (R)-(+)-3-chlorine-phenylpropanol mono-spin-body. The optical purity of undetached (R)-(+)-3-chlorine-phenylpropanol is more than 90%e.e..

The invention discloses an application of a novel microbial strain Saccharomyces cerevisiae CGMCC No.2230 in microbial transformation preparation of (S)-(-)-3-chlorine-1-phenylpropanols. The application of the invention is that: 3-chlorine-1-propiophenones are taken as substrates, and immobilized cell particles which are prepared by fermentation broth obtained after fermentation of the Saccharomyces cerevisiae strain CGMCC No.2230 are taken as biocatalysts; transformation reaction time of transformation liquid is 8 to 72 hours at the temperature of 25 to 30 DEG C in dibutyl phthalates, and the product S)-(-)-3-chlorine-1-phenylpropanols are obtained after separation and purification of the transformation liquid. The microbial transformation method has the advantages of friendly surroundings, mild reaction conditions, simple product separation, high substrate transformation ratio, good product purity and biocatalysts capable of being reused, and is suitable for commercial process.

The invention provides a high temperature resistant optical fiber and a preparation method thereof. The high temperature resistant optical fiber comprises an optical fiber core layer, a cladding layerand a double-layer coating, wherein, the coating material of an inner coating is composed of an acrylate oligomer, 2-hydroxyl-2-methyl propiophenone, vinyl tri(2-methoxy ethoxyl) silane and (2,4,6-trimethyl benzoyl)diphenyl phosphine xide; an outer coating is a high temperature resistant acrylic resin outer coating. The high temperature resistant optical fiber still maintains the reliability of optical transmission at a high temperature environment of 150DEG C for a long time, optical fiber coating has no aging phenomena of yellowing and blackening. The method is simple. The optical fiber transmission loss of the high temperature resistant optical fiber prepared at the wiredrawing speed of 2000-2200m/min, the attenuation value of the optical fiber at 1550nm is not more than 0.25dB/km, theadditional attenuation value of the optical fiber at environment of 150DEG C for a long time is not more than 0.05dB/km.

The invention discloses a compounding method for a beta-aryl propiophenone compound. The compounding method is characterized by taking chalcone compounds as reaction substrates, and selectively chemically reducing the carbon-carbon double bonds in the reaction substrates at 100-160 DEG C under the accelerating effect of inorganic alkaline and elemental selenium under the nitrogen condition in an organic solvent, thereby acquiring the beta-aryl propiophenone compound. The invention has the beneficial effects of mild reaction condition, simple and convenient operation, high functional tolerance, high reaction efficiency, high yield and purity, simple post-processing, reasonable price and suitability for large-scale industrial production.

A disclosed preparation method for erythro-structure methoxamine hydrochloride comprises the following steps: (1) dissolving an initial raw material 2,5-dimethylpropiophenone in an organic solvent, under the condition of introducing dry hydrogen chloride gas, dropwise adding a 1-butyl nitrite solution to perform an oximation reaction, so as to obtain an intermediate I; (2) under the acidic condition, taking a methanol solution as a solvent, take palladium on activated carbon as a catalyst, employing hydrogen to reduce the oximido group in the intermediate I, so as to obtain an intermediate II; and (3) performing hydrogenation reduction reaction on the intermediate II to obtain the erythro-structure methoxamine hydrochloride. The method provided by the invention is simple in operation, economic, environment-friendly, mild in reaction conditions, excellent in product quality and high in yield, and can help to obtain the single erythro-structure methoxamine hydrochloride.

The invention relates to an ultraviolet (UV) cured paint. The UV cured paint is prepared from the following raw materials in part by weight: 50-60 parts of epoxy acrylate, 20-25 parts of methacrylate, 6-8 parts of 2-hydroxyl-2-methyl-propiophenone, 10-12 parts of dimethylaminoethyl methacrylate, 1-2 parts of polyoxyethylene stearate, 10-12 parts of dipentaerythritol hexaacrylate, 3-5 parts of ethylene glycol monoethyl ether acetate, 1-2 parts of a silane coupling agent KH-550, 3-4 parts of an accelerator DM, 2-3 parts of acrylic acid-4-polyhydroxybutyrate, 1-2 parts of glycidyl methacrylate, 2-3 parts of bis tetradecene ester, 1-2 parts of an antioxidant DSTP (disteaxylthiodipropionate), and 4-5 parts of a dispersing aid. The UV paint is suitable for priming paints of hardware, zinc alloy, aluminium alloy, stainless steel, and vacuum plating coating UV, has lasting performance and strong universality, and meets the ROHS (Restriction Of Hazardous Substances) requirements.

The invention discloses a UV scratch-resistant agent of an organic-inorganic composite system and a preparation method and an application of the UV scratch-resistant agent. The UV scratch-resistant agent comprises the following raw materials by the weight percentage: 26-34% of a urethane acrylate oligomer, 2.4-6.4% of a nano silicon dioxide dispersion liquid, 0.3% of an adhesion promoter, 44-52% of a solvent, 0.3% of a reactive leveling agent, 3% of a macromolecular photoinitiator and 12% of an acrylate reactive diluent, wherein the sum of the weight percentages of the raw materials is 100%. The urethane acrylate oligomer comprises a urethane acrylate oligomer with six functional groups; the adhesion promoter comprises a phosphate modified acrylate oligomer; the leveling agent comprises acrylic acid modified polysiloxane; the macromolecular photoinitiator comprises 2-hydroxy-4-(2-hydroxyethyl)-2-methyl propiophenone. After coating the surface of a window film and being cured into a film, the scratch-resistant agent has the characteristics of low odor, high hardness, good adhesive force, excellent wear resistance and the like, and meets the index requirements of the window film market on film hardening treatment.

The invention provides a printed circuit board base plate and a preparation method thereof. The base plate comprises the components of bisphenol A benzoxazine, bisphenol A epoxy resin, silicon resin, p-aminophenol triglycidyl epoxy resin, N,N-dimethylformamide, alkali-free glass fiber cloth, triethylamine, silicic acid anhydride, phenol-formaldehyde resin, polyamide polyamine epichlorohydrin, methylbenzene, acetone, propyl gallate and copper foil. The preparation method comprises the following steps: heating to dissolve bisphenol A benzoxazine, N,N-dimethylformamide, triethylamine, methylbenzene, acetone and propyl gallate at first; then adding the other components except for the alkali-free glass fiber cloth and gold foil, and stirring to obtain a steeping glue solution; removing steeped alkali-free glass fiber cloth; and then baking to obtain a prepreg, superimposing the prepreg with the copper foil, and cooling in a press after heat and pressure preservation. The printed circuit board base plate provided by the invention has the advantages of good insulating property, heat resistance and caking property and low cost; moreover, the production process is relatively simple and is suitable for industrial production.

The invention relates to an enameled wire paint remover as well as a preparation method and a use method thereof. The enameled wire paint remover is characterized by being prepared from the following components in parts by weight: 20-30 parts of dichloromethane, 13-16 parts of diethylene glycol monomethyl ether, 10-15 parts of ethanol, 8-12 parts of glycol, 0.3-0.8 part of dimethyl sulfoxide, 4-6 parts of sodium dodecyl benzene sulfonate, 0.02-0.1 part of 98 percent by weight of concentrated sulfuric acid and the balance of water. The preparation method comprises the following steps: uniformly mixing the dichloromethane, the diethylene glycol monomethyl ether and the dimethyl sulfoxide to obtain liquid A; uniformly mixing the ethanol, the glycol, sulfuric acid, the sodium dodecyl benzene sulfonate as a surface active agent and the water to obtain liquid B; uniformly mixing the liquid A and the liquid B to obtain a finished product. Compared with an existing organic paint remover, the enameled wire paint remover contains no benzene, acetone and other poisonous substances, is low in cost, green and environment-friendly, and quick and efficient in paint removal, does not corrode a copper substrate, is prepared and used at a normal temperature, is mild in use condition and has the advantage of being simple and convenient to operate, time-saving and labor-saving.

The invention relates to a method for preparing 2-(4-Chloromethylphenyl) propionic acid as a loxoprofen key intermediate. The method comprises the following steps of: condensing methyl benzene as a starting raw material with propionyl chloride to obtain methyl propiophenone, carrying out bromination and methoxycarbonylation through a one-step method on the obtained methyl propiophenone, hydrolyzing to obtain 2-(p-tolyl)propionic acid, and finally carrying out chlorination on the 2-(p-tolyl)propionic acid to obtain the 2-(4-Chloromethylphenyl) propionic acid. According to the method disclosed by the invention, the methyl propiophenone can be prepared from methyl; the key intermediate 2-(p-tolyl)propionic acid can be obtained directly through a one-step one-pot method; the intermediate is chlorinated under the conditions of quantitatively illuminating and charging chlorine in petroleum ether so that the loxoprofen is finally synthesized; and in addition, the production process is very short and the wastewater amount is small.

The invention discloses a copper bromide reagent, a preparation method thereof, and a synthesis method of alpha-amido propiophenone and derivative thereof. Copper bromide cheap in industry and 2,6-bi[4-(1,1-dimethyl)-2-oxazoline-2-base] pyridine react to directly obtain high yield of high-purity copper bromide reagent, in addition, the copper bromide reagent and propiophenone containing multiple important functional groups have good reaction activity. Due to the characteristic, high yield of alpha-amido propiophenone and derivative thereof can be obtained in mild conditions, conventional expensive azoic compound materials are not used, the cost is lowered to a large extent, the operation requirement is also lowered, and alpha-amido propiophenone and derivative thereof have good application prospect in industry.

A preparation method of hydroxyl-terminated styrene resin belongs to the technical field of high molecular materials. In an ultraviolet reactor, an ultraviolet initiator of 2-hydroxyl-4-(2-hydroxyethoxy)-2-methyl propiophenone (2959) and refined styrene monomers are added; nitrogen is injected; polymerization is carried out through the initiation by ultraviolet light irradiation at room temperature, and unreacted styrene monomers are removed at a reduced pressure; and thus the hydroxyl-terminated styrene resin is obtained. The preparation method of the invention is easily available in raw materials, low in cost, simple, practical, and suitable for large-scale industrial production, and provides a new approach for the preparation of polystyrene resin with reactivity.

The invention provides a MSn (OH) 6 photocatalyst and preparing method and application thereof. M=Mg, Ca, Sr. In the invention, alkaline earth metal nitrate and stannic chloride pentahydrate are used as raw materials to obtain MSn (OH)6 photocatalyst through further sediment. The prepared MSn (OH) 6 photocatalyst is applied for photocatalytic gas phase degradation of volatile organic pollutants, namely benzene, formaldehyde and acetone. The photocatalyst has low preparing cost, raw materials easy to get and simple manufacturing technique, and can be produced in large scale and used for degradation of volatile organic pollutants in the air and room, which is beneficial to sustainable development of environment purification and human society.