The invention relates to a medicine for treating wound infection after surgical operation, comprising 12 Chinese medicines including pteris vittata, angelica sinensis, elephant leather, membrana follicularis ovi, pearl powder, crinis carbonisatus, rhubarb, radix scrophulariae, panax pseudoginseng, red halloysite, myrrh and borneol, wherein the Chinese medicines bring out the best in each other, jointly strengthen the body resistance and reinforce the body, and are exact in drug properties, free of toxic and side effects, and convenient to take, and the medicine is simple in preparation technology, low in price, quick in treatment speed, reliable in therapy, and compact in formation, can expel the rottenness, extract the toxin, promote blood circulation to remove blood stasis, engender flesh and close wounds, and invigorate qi and blood, is free from sequelae, can improve the blood running condition of wounds, and is simple and easy in preparation method, so that the wound infection after surgical operation can be effectively controlled, the wound heal can be accelerated, the wound treatment can be accelerated, and the problem that the wound infection after surgical operation is unhealed after being treated by the Chinese medicines can be solved.