Method for preparing personalized bionic drug eluting coronary stent by using 3D printing technology

A coronary artery and 3D printing technology, applied in the field of medical devices, can solve problems such as conical/special-shaped blood vessel stenosis, and achieve the effects of reducing the rate of revascularization, reducing mortality, and shortening the production cycle

Inactive Publication Date: 2016-08-24
周玉杰 +3
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Problems solved by technology

[0008] The technical problem to be solved by the present invention is to provide a method for preparing a personalized bionic drug-eluting coronary stent using

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  • Method for preparing personalized bionic drug eluting coronary stent by using 3D printing technology
  • Method for preparing personalized bionic drug eluting coronary stent by using 3D printing technology

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[0028] In order to make the purpose, technical solution and advantages of the patent of the present invention clearer, the patent of the present invention will be further described in detail below in conjunction with specific embodiments and with reference to the accompanying drawings.

[0029] Clinically, the location and shape of different coronary artery lesions vary, especially at the end of the left main artery and the opening of the anterior descending and circumflex branches. There is often a large difference in diameter between the proximal end and the distal end of the diseased blood vessel. However, current data show that tapered coronary arteries are very common clinically.

[0030] figure 1 It is an angiogram of a case of tapered coronary artery disease. As shown in the figure, coronary angiography shows diffuse lesions in the patient's left main-anterior descending artery, but the diameter of the left main lumen is about 4.5cm, and the diameter of the anterior des...

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Abstract

The invention discloses a method for preparing a personalized bionic drug eluting coronary stent by using a 3D printing technology and a product. The method for preparing the personalized bionic drug eluting coronary stent comprises the step that according to image data of coronary angiogram, adopting a QCA technique for measuring the diameter of a diseased coronary artery and reconstructing in a three-dimensional manner. According to indexes such as lesion vascular diameter, lesion length and lesion vascular pattern, a personalized coronary stent can be made for each patient in a customized manner and a stent most suitable for the lesion state of a patient can be prepared. The personalized bionic drug eluting coronary stent can be made of degradable poly L-lactic acid (PLLA) or other materials, after 3D printing molding, the surface of the stent can be coated with a polymer with anti-proliferation medicines by using a conventional process, and in-stent restenosis can be reduced (the polymer is prepared by mixing a medicine with PDLLA in a ratio of the medicine to PDLLA being 1:1). The most suitable personalized bionic drug eluting coronary stent can be customized for the patient according to diseased coronary arteries of different states, requirements of different lesions can be met, customization of coronary stents can be achieved, and complications such as vascular injury, thrombus and coronary arterial dissection caused by mismatching of the diameter of the stent and that of the blood vessel can be reduced.

Description

technical field [0001] The invention belongs to the technical field of medical devices, and in particular relates to a method and product for manufacturing a personalized bionic drug-eluting coronary stent by using 3D printing technology. Background technique [0002] 3D printing technology (also known as 3D rapid prototyping technology or additive manufacturing technology) is a new manufacturing technology that gradually emerged in the late 1980s. Or the analysis of data such as computerized tomography (CT), through the precise 3D accumulation of materials, a new digital molding technology for rapidly manufacturing 3D objects with arbitrary complex shapes, and has been applied in many fields. [0003] 3D printing is a subversive manufacturing technology, which refers to the principle of printer technology for layered processing. If the traditional manufacturing technology is "subtractive manufacturing technology", then 3D printing is "additive manufacturing technology", wh...

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Application Information

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IPC IPC(8): A61F2/90B33Y10/00B33Y50/00
Inventor 周玉杰孙伟马茜张磊
Owner 周玉杰
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