18 results about "Airway wall" patented technology

An atomization assembly includes a housing assembly and a heating element. The housing assembly is formed with an e-liquid tank and an atomization tank spaced apart from each other. The housing assembly is further formed with an air inlet channel and a vent channel. The air inlet channel is in communication with the atomization tank. The vent channel is in communication with the e-liquid tank. The atomization tank is isolated from the vent channel. The housing assembly includes an air channel wall forming the vent channel. The air channel wall is at least partially located in the atomization tank.

The application discloses a spoiler assembly for a vehicle and the vehicle, the spoiler assembly comprises a base body, a first air guide and a second air guide, the base body is suitable for being connected with the back of the vehicle body, the base body extends in the width direction, the upper surface of the base body is formed with an air guide surface, the first air guide and the second air guide are symmetrically arranged at the two ends of the base body, at least part of the first air guide and at least part of the second air guide protrude from the air guide surface, the first air guide and the second air guide are arranged in the vehicle width direction, wherein the two side edges of the first air guide and the second air guide towards each other are respectively formed with a first air channel wall and a second air channel wall, the first air channel wall and the second air channel wall are arranged away from each other in the direction close to the air guide surface, a first concave air channel is formed between the first air channel wall and the air guide surface, and a second concave air channel is formed between the second air channel wall and the air guide surface, so that the wind resistance of the vehicle can be further reduced.

An access tool for piercing an airway wall including a dilating member (308) having a minimally traumatic tip formed on a distal end, a piercing member (302) having a piercing tip on a distal and a handle (304) formed on a proximal end, and a spring-loaded actuator (406) connecting the piercing member and the dilating member such that upon actuation the piercing member is urged in the direction of the dilating member.

The invention discloses a catheter system for treating chronic obstructive pulmonary disease through two-stage pulsed electric field ablation, and the system comprises a two-stage electrode assembly which is used for guaranteeing that current only flows between specific electrodes; the handle regulation and control mechanism is used for dynamically adjusting the size of the electrode so as to adapt to different airway diameters; imaging probes, integrated OCT and / or ultrasound, for providing real-time airway wall structure and tissue condition monitoring. By means of the technical scheme, the problems that in the prior art, current flows through deep tissue in the ablation process of a single-stage system, and risks are caused due to incomplete electrode coverage can be effectively solved.

The invention discloses a lung function training device which comprises a shell, an air outlet end and a blowing nozzle are arranged at the left end and the right end of the shell respectively, a fixing base is arranged on the side, close to the air outlet end, of the inner wall of the shell, a reed is fixedly connected to the side face of the fixing base, and a bypass cavity is formed in the side, close to the blowing nozzle, of the inner wall of the shell. By arranging the shell, the reed and the diaphragm, firstly, a patient actively blows air to impact the reed, so that the reed generates a primary vibration source, when the frequency of pressure pulsation generated by the reed is close to or consistent with the inherent frequency of the diaphragm, the diaphragm enters a resonance state, then the diaphragm generates an ultimate vibration source, vibration is transmitted to the whole shell, and the vibration is transmitted to the whole shell. The high-frequency vibration is utilized to effectively reduce the viscosity and adhesive force of sputum, so that the sputum is loosened from the airway wall, and exhaled air flow generated by blowing can also help the loosened sputum to move towards the oral cavity.

The invention discloses an infant airway collaborative intubation safety control system based on different-place mixed reality. The system aims at solving the problems of space synchronization robustness and predictive time delay compensation in remote guidance, a mapping relation between a local coordinate system and a remote coordinate system is established through a space synchronization module, a long short-term memory (LSTM) network is used for predictive compensation of a remote expert track, and visual lag is eliminated. The core safety mechanism comprises the steps that the airway dynamic model module generates a real-time dynamic signed distance field (D-SDF); the risk prediction module calculates the dynamic collision risk probability of the laryngoscope tail end and the dynamic airway wall in real time. The tactile feedback device responds to the risk probability, adopts a variable admittance control strategy, generates an operation viscous sense by nonlinearly increasing virtual damping, and activates a virtual stiffness item pointing to a safety area when the risk exceeds a critical value, so as to apply a reverse elastic restoring force and realize active safety avoidance in a physical level. And the submillimeter precision and safety of the airway operation of the infant are ensured.

The invention provides an acute respiratory tract obstruction airway unobstructing device, and belongs to the technical field of medical treatment, the device comprises a connecting suction tube, a sputum suction head and a negative pressure suction mechanism, the sputum suction head is arranged at the insertion end of the connecting suction tube, the sputum suction head comprises a suction head front part and a suction head rear part, the suction head front part and the suction head rear part can move relatively in the axial direction, and the suction head front part and the suction head rear part are arranged on the connecting suction tube. The rear portion of the suction head is rotationally connected with the connecting suction pipe, the negative pressure suction mechanism is arranged at the far end of the insertion end of the connecting suction pipe, and a suction hole is formed in the surface of the rear portion of the suction head. An elastic film is arranged in the suction hole, the interior of the elastic film is of an annular double-layer structure, and the opening end of the elastic film is fixedly connected with the inner surface of the suction hole, and through the synergistic effect of the elastic film and the pore diameter adjusting and controlling mechanism, the pore diameter of the suction hole can be automatically adjusted according to the pressure change at the suction hole; airway injury caused by negative pressure adsorption is avoided, and the technical defect that suction holes are adsorbed to the airway wall due to sputum accumulation in the sputum suction process of an existing airway unobstructed device is overcome.

The invention discloses application of bifidobacterium animalis in relieving respiratory tract allergy symptoms, and belongs to the technical field of microorganisms. The technical problem to be solved is to provide the application of the bifidobacterium animalis in relieving the respiratory tract allergy symptoms, the key point of the technical scheme is the application of the bifidobacterium animalis subsp. Lactis BL-5M in relieving the respiratory tract allergy symptoms, and the preservation number of the bifidobacterium animalis subsp. Lactis BL-5M is CGMCC (China General Microbiological Culture Collection Center) No.33449. The medicine can act on the core mechanism of respiratory tract allergy, and the sneezing / cough frequency caused by respiratory tract stimulation reflex is reduced; the lung tissue enlargement mediated by allergic inflammation is relieved; the ratio of eosinophilic granulocytes in bronchoalveolus is reduced; the concentration of proinflammatory factors IL-4 and IL-5 in bronchoalveolus alveolus is reduced; inflammatory cell infiltration around the lung airway wall is reduced; the IgE content in a body circulation system or local tissues is reduced, meanwhile, the diversity of intestinal flora is improved, anti-inflammatory functional flora is accurately enriched, and the allergic asthma is improved in a targeted manner.

The application provides an atomizer and an atomization device. The atomization device comprises a battery assembly and an atomizer. The battery assembly is used for supplying power for the atomizer. The atomizer comprises an air passage wall and a flow dividing member. The air passage wall is surrounded to form an air outlet channel. An inner surface of the air passage wall is concavely provided with a mounting groove in communication with the air outlet channel. The flow dividing member is at least partially arranged in the mounting groove. A side of the flow dividing member facing the air outlet channel is provided with a flow dividing portion for dividing condensate. The flow dividing portion is recessed relative to the inner surface of the air passage wall or flush with the inner surface of the air passage wall. According to the application, the flow dividing portion is recessed relative to the inner surface of the air passage wall or flush with the inner surface of the air passage wall, so that the flow dividing portion does not extend into the air outlet channel. The arrangement of the flow dividing portion does not affect the smoothness of airflow, that is, the arrangement of the flow dividing portion does not affect the smoking taste, thereby improving the user's smoking experience.

The invention relates to the technical field of medical instruments, in particular to a diameter-adaptive anesthesia intubation device which comprises a trachea cannula, an adjusting module and a control module. The adjusting module comprises a radial actuating assembly and a detection assembly, the radial actuating assembly is embedded in the trachea cannula, the detection assembly is arranged on the trachea cannula, and the detection assembly is used for detecting the contact pressure between the trachea cannula and the airway wall; the control module is electrically connected with the radial actuating assembly and the detection assembly, and the control module is used for controlling the radial actuating assembly to adjust the tube diameter of the trachea cannula according to the contact pressure detected by the detection assembly. The device has the effect of reducing the risk of airway injury or untight ventilation sealing.

Systems and methods involve abrading a patient lung airway wall to reduce mucus production therein. Exemplary techniques include rotationally and / or linearly oscillating an abrasive material against the airway wall so as to damage mucus producing tissues, for example by removing goblet cells, while destroying less than the entire airway wall. The abrasive material may be present on the surface of an expandable balloon body or another expandable device, which can be delivered to the patient treatment site via a bronchoscope. In some cases, the abrasion techniques can cause cell damage or death at a controlled or predetermined tissue depth.

The embodiment of the invention provides an aerosol generating substrate section and an aerosol generating product, and the aerosol generating substrate section comprises a peripheral wall and an airway wall; a containing space is defined by the peripheral wall, the peripheral wall has a first length size in the first direction and a second length size in the second direction, the first direction is perpendicular to the second direction, and the first length size is smaller than the second length size; the air channel walls are arranged in the containing space, the containing space is divided into a plurality of airflow channels by the air channel walls, the air channel walls at least comprise the first air channel wall, and the first air channel wall is connected with the two opposite sides of the peripheral wall in the first direction. According to the aerosol generating substrate section, a good suction experience feeling can be provided, and the structural strength is high.

The application provides an acute respiratory tract obstruction airway patency device, belonging to the technical field of medical treatment, comprising a connecting suction pipe, a sputum suction head and a negative pressure suction mechanism, the sputum suction head is arranged at the insertion end of the connecting suction pipe, the sputum suction head comprises a suction head front part and a suction head rear part, the suction head front part and the suction head rear part are relatively movable along the axial direction, the suction head rear part is rotationally connected with the connecting suction pipe, the negative pressure suction mechanism is arranged at the distal end of the insertion end of the connecting suction pipe, and the surface of the suction head rear part is provided with a suction hole; an elastic membrane is arranged in the suction hole, the inside of the elastic membrane is provided with a ring-shaped double-layer structure, and the opening end of the elastic membrane is fixedly connected with the inner surface of the suction hole; through the cooperation of the elastic membrane and the hole diameter control mechanism, the hole diameter of the suction hole can be automatically adjusted according to the pressure change of the suction hole, airway injury caused by negative pressure adsorption is avoided, and the technical defects that the existing airway patency device causes the suction hole to adsorb the airway wall due to sputum accumulation during sputum suction are solved.

The application discloses a kind of based on off-site mixed reality infant airway collaborative intubation safety control system.The system aims to solve the problem of space synchronization robustness and predictive latency compensation in remote guidance, the mapping relationship between local and remote coordinate system is established by space synchronization module, and the trajectory of remote expert is predicted and compensated by using long short-term memory network (LSTM), to eliminate visual lag.The core safety mechanism includes: airway dynamic model module generates real-time dynamic signed distance field (D-SDF);Risk prediction module calculates the dynamic collision risk probability of laryngoscope tip and dynamic airway wall in real time.Tactile feedback device responds to risk probability, adopts variable admittance control strategy, generates operation stickiness by nonlinearly increasing virtual damping, and when risk exceeds the critical value, activates the virtual stiffness term pointing to the safety area to apply reverse elastic restoring force, realize active safety avoidance in physical level, guarantee the sub-millimeter level precision and safety of infant airway operation.

The application discloses application of fresh bamboo juice effective part in preparation of a medicine for treating chronic obstructive pulmonary disease, and belongs to the technical field of medicines.The fresh bamboo juice effective part contains phenolic substances such as guaiacol, 4-ethylphenol, 4-methylguaiacol, 4-ethylguaiacol, p-vinylguaiacol, 2,6-dimethoxyphenol and dihydroeugenol, and the application has been verified to have the effect of significantly relieving airway mucus hypersecretion caused by the syndrome of external cold and internal fluid retention, can simultaneously inhibit multiple inflammatory factors, and reduce inflammatory infiltration of lung tissue, alleviate emphysema, restore lung tissue elasticity, improve lung function and airway wall thickness, and the like.The application provides a new and effective medicine selection for treatment of chronic obstructive pulmonary disease, and is especially suitable for the disease caused by external cold and internal fluid retention, and has a wide application prospect and important clinical value.

The present disclosure relates to the technical field of endoscopy, and provides a path planning method. In the method, a cross-sectional image of a target object and hardware parameters of a bronchoscope robot corresponding to the target object are obtained; according to the cross-sectional image of the target object, lesion feature information, trachea feature information and blood vessel feature information of the target object are determined; according to the hardware parameters of the bronchoscope robot, and the lesion feature information, the trachea feature information and the blood vessel feature information of the target object, an airway wall puncture biopsy path of the bronchoscope robot is determined. In this way, since multiple constraint conditions are considered in the generation process of the airway wall puncture biopsy path, the most efficient and safe airway wall puncture biopsy path can be obtained, thereby the problems of subjectivity and human error that occur when a scheme is artificially formulated can be avoided, and thus the airway wall puncture biopsy path obtained by the embodiment is more accurate and has more reference value, and the safety and efficiency of the puncture biopsy are also improved.

This invention belongs to the field of new pharmaceutical technology and relates to a nebulized inhalation formulation for treating chronic obstructive pulmonary disease (COPD) and asthma, and its preparation method. Specifically, it relates to a nebulized inhalation solution formulation of an aminotetraphenylporphyrin photosensitizer (D4) with high light sensitivity. This invention uses an aminotetraphenylporphyrin photosensitizer (D4) as the active ingredient for treating COPD and asthma. The prepared D4 nebulized inhalation formulation comprises the following components: 200-400 μg / ml of the small molecule compound D4 solution, 0.1%-0.6% w / w acrylic polymer carbopol / 3%-25% w / w poloxamer 407 / 3%-25% w / w poloxamer 188, appropriate amounts of isotonic agent, pH adjuster, and purified water. The D4 nebulized inhalation formulation prepared by this invention, after excitation with a 650nm laser, shows significant therapeutic effects on COPD and asthma. After treatment, the alveolar septa narrowed, inflammatory infiltration decreased, airway changes were alleviated, and the thickness of the airway wall, smooth muscle layer, and basement membrane layer decreased. This method is highly effective, low in toxicity, highly targeted, has high nebulization efficiency, a short treatment cycle, and the preparation method is simple, convenient, and reliable, facilitating the establishment of quality control standards in production and promoting drug quality monitoring and large-scale production.

The invention relates to the technical field of medical equipment, in particular to an ablation device.The ablation device comprises an ablation support, one or more protection pieces and one or more electrode assemblies, the ablation support comprises a pushing pipe and an ablation head connected with the far end of the pushing pipe, and the ablation head comprises one or more ablation parts; the ablation head has a radial compression state and a radial expansion state, in the process of switching from the radial compression state to the radial expansion state, the ablation parts move in the direction away from the central axis of the pushing pipe, the peripheral surface of at least one ablation part is provided with a protection piece used for overheating protection, and at least one protection piece is provided with an electrode assembly. According to the ablation device, the risk that the ablation device burns the inner wall of the airway in the ablation process is reduced.