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7 results about "Mechanical index" patented technology

Mechanical index (MI) is an ultrasound metric. It is defined as MI=PNP/√(Fc), where PNP is the peak negative pressure of the ultrasound wave (MPa), derated by 0.3 dB cm⁻¹ MHz⁻¹ to account for the difference between in-water and in-tissue acoustic attenuation, and Fc is the center frequency of the ultrasound wave (MHz). MI is measured with a calibrated hydrophone in a tank of water. Derated (0.3 dB/cm/MHz) Pulse Pressure Squared Integral (ppsi) values are measured along the axis of the ultrasound beam.

Ultrasonic plane wave multi-mode cooperative imaging method and system

The invention provides an ultrasonic plane wave multi-mode cooperative imaging method and system, and the method comprises the steps: controlling an ultrasonic probe to execute shear wave elastic imaging and sound attenuation imaging of which the mechanical index is equal to or greater than a first threshold value based on a multi-level voltage control scheme; and executing super-resolution imaging with the mechanical index smaller than or equal to a second threshold value after the super-resolution imaging is completed. The method comprises the following steps: acquiring a sound attenuation coefficient graph generated in a sound attenuation imaging process, and respectively acquiring a first super-resolution graph without contrast agent perfusion, a second super-resolution graph with contrast agent perfusion and a tissue elasticity graph generated in a shear wave elasticity imaging process based on an ultrafast plane wave technology; performing post-processing on the collected first super-resolution graph to generate a probability density graph of the tissue structure, and performing post-processing on the collected second super-resolution graph to generate a microbubble tracking speed graph; and carrying out cooperative imaging on the tissue elasticity map, the sound attenuation coefficient map, the probability density map and the velocity map. The imaging comprehensiveness and accuracy are improved, and early lesion diagnosis is facilitated.
Owner:ESONIC MEDICAL TECHNOLOGY (BEIJING) CO LTD

Methods and systems of improving medical conditions via ultrasound neuromodulation of the brain

PendingUS20260137963A1Ultrasound therapyMechanical indexAssociated anxiety
Methods and systems for improving medical conditions by delivering a focused ultrasound signal to target sites of the brain. The focused ultrasound signal can have a mechanical index of between about 1.0 to about 8.0 and / or an acoustic pressure of between about 1.0 MPa to about 3.0 MPa. The medical condition can comprise addiction (including binge eating), anxiety disorders and anxiety associated disorders, tinnitus, neurodegenerative disorders, neuropsychiatric disorders, cognitive disorders, neurodevelopmental disorders, post-traumatic stress disorder, stroke recovery, and combinations thereof.
Owner:WEST VIRGINIA UNIV BOARD OF GOVERNORS ON BEHALF OF WEST VIRGINIA UNIV

A method for testing the dynamic compressive mechanical properties of ice structures

This invention relates to the field of ice mechanical performance testing technology and discloses a method for testing the dynamic compression mechanical properties of ice structures. The method includes simultaneously acquiring three-dimensional coordinates, time series, acoustic emission signals, and thermal infrared images of an ice structure during dynamic compression using multiple sensors to construct a multimodal dataset; extracting mechanical indices, acoustic features, and thermodynamic parameters after spatiotemporal alignment processing to generate an integrated feature set; automatically identifying consistent and abnormal regions based on spatial distance and feature similarity; simulating the evolution of mechanical properties under different working conditions using consistent region data; calculating anomaly risk indices by combining acoustic energy distribution and infrared temperature difference changes to form a high-risk point set; and finally generating a risk warning report through failure mode identification. This method achieves multi-dimensional automated evaluation of the mechanical properties of ice structures, accurately locating defective areas and quantifying risk levels, thus improving the accuracy of testing and analysis and the ability to provide early warnings.
Owner:HEILONGJIANG UNIV

Methods and systems of improving medical conditions via ultrasound neuromodulation of the autonomic nervous system

PendingUS20260069895A1Ultrasound therapyNervous systemMechanical index
Methods and systems for improving medical conditions by delivering a focused ultrasound signal to target sites of the autonomic nervous system. The focused ultrasound signal can have a mechanical index of between about 0.1 to about 5.0 and / or an acoustic pressure of between about 0.1 MPa to about 2.5 MPa. The medical condition can comprise chronic or refractory rhinitis, chronic rhinosinusitis, autonomic instability / autonomic dysfunction, functional gastrointestinal disorders, inflammatory disorders, immune disorders (including improving cancer and infections by neuromodulation of immune function), complex regional pain syndrome, post-traumatic stress disorder (PTSD), anxiety and anxiety-associated disorders, autism, fibromyalgia, uterine function, metabolic disorder, urinary incontinence or binge eating.
Owner:WEST VIRGINIA UNIV BOARD OF GOVERNORS ON BEHALF OF WEST VIRGINIA UNIV

Methods and systems of improving medical conditions via ultrasound neuromodulation of the brain

PCT designated stageWO2026096334A1Ultrasound therapyMechanical indexCognitive disorder
Methods and systems for improving medical conditions by delivering a focused ultrasound signal to target sites of the brain. The focused ultrasound signal can have a mechanical index of between about 1.0 to about 8.0 and / or an acoustic pressure of between about 1.0 MPa to about 3.0 MPa. The medical condition can comprise addiction (including binge eating), anxiety disorders and anxiety associated disorders, tinnitus, neurodegenerative disorders, neuropsychiatric disorders, cognitive disorders, neurodevelopmental disorders, post-traumatic stress disorder, stroke recovery, and combinations thereof.
Owner:WEST VIRGINIA UNIV BOARD OF GOVERNORS ON BEHALF OF WEST VIRGINIA UNIV

Methods and systems for improved delivery via ultrasound

Methods are provided for improving expression of a nucleic acid construct in a cell or organ of a subject using sonoporosis and optimization of the ultrasonic acoustic energy mechanical index.
Owner:SONOTHERA INC

Methods and systems of improving medical conditions via ultrasound neuromodulation of the autonomic nervous system

PCT designated stageWO2026059975A1Ultrasound therapyNervous systemMechanical index
Methods and systems for improving medical conditions by delivering a focused ultrasound signal to target sites of the autonomic nervous system. The focused ultrasound signal can have a mechanical index of between about 0.1 to about 5.0 and / or an acoustic pressure of between about 0.1 MPa to about 2.5 MPa. The medical condition can comprise chronic or refractory rhinitis, chronic rhinosinusitis, autonomic instability / autonomic dysfunction, functional gastrointestinal disorders, inflammatory disorders, immune disorders (including improving cancer and infections by neuromodulation of immune function), complex regional pain syndrome, post-traumatic stress disorder (PTSD), anxiety and anxiety-associated disorders, autism, fibromyalgia, uterine function, metabolic disorder, urinary incontinence or binge eating.
Owner:WEST VIRGINIA UNIV BOARD OF GOVERNORS ON BEHALF OF WEST VIRGINIA UNIV