52results about How to "Pain control" patented technology

A method and apparatus for treatment of cardiac and renal diseases associated with the elevated sympathetic renal nerve activity by implanting a device to block the renal nerve signals to and from the kidney. The device can be a drug pump eluting implant for targeted delivery of a nerve-blocking agent to the periarterial space of the renal artery.

A microenvironment of a biological body is controlled, and more particularly, is measured, changed, and monitored with respect to temperature, pH level, moisture and other tissue parameters of a region of the body while, optionally, administering a therapeutic agent to that region.

Methods and devices are disclosed for controlled mediation and / or improvement of inflammation, inflammation associated with pain, and pain by delivering non-ablative thermal tissue damage to portions of a region of tissue including a volume of inflamed tissue, thereby activating the immune systems pain relief response to the tissue damage.

A pharmaceutical composition contains a nitric oxide donor and advantageously an optional corticosteroid and / or topical anesthetic. The composition is useful in a method for treating anal disorders such as anal fissure, anal ulcer, hemorrhoidal disease, levator spasm, and so forth, by topical application to or proximate the affected area.

Methods and compositions for inhibiting articular cartilage degradation. The compositions preferably include multiple chondroprotective agents, including at least one agent that promotes cartilage anabolic activity and at least one agent that inhibits cartilage catabolism. The compositions may also include one or more pain and inflammation inhibitory agents. The compositions may be administered systemically, such as to treat patients at risk of cartilage degradation at multiple joints, and suitably may be formulated in a carrier or delivery vehicle that is targeted to the joints. Alternatively the compositions may be injected or infused directly into the joint.

A method and solution for perioperatively inhibiting a variety of pain and inflammation processes during arthroscopic procedures. The solution preferably includes a vasoconstrictor that demonstrates substantial agonist activity at alpha adrenergic receptors and that is selected for peripheral (local) vasoconstriction and one or more additional pain and inflammation inhibitory agents at dilute concentration in a physiologic carrier, such as saline or lactated Ringer's solution. The solution is applied by continuous irrigation of a wound during a surgical procedure for peripheral vasoconstriction and inhibition of pain and / or inflammation while avoiding undesirable side effects associated with systemic application of larger doses of the agents.

A formulation and methods for inducing sustained regional local anesthesia in a patient comprising a substrate comprising a local anesthetic and an effective amount of a biocompatible, biodegradable, controlled release material prolonging the release of the local anesthetic from the substrate to obtain a reversible local anesthesia when inplanted or injected in a patient, and a pharmaceutically acceptable, i.e., non-toxic, non-glucocorticoid augmenting agent effective to prolong the duration of the local anesthesia for a time period longer than that obtainable from the substrate without the augmenting agent.

A formulation and methods for inducing sustained regional local anesthesia in a patient comprising a substrate comprising a local anesthetic and an effective amount of a biocompatible, biodegradable, controlled release material prolonging the release of the local anesthetic from the substrate to obtain a reversible local anesthesia when implanted or injected in a patient, and a pharmaceutically acceptable, i.e., non-toxic, non-glucocorticoid augmenting agent effective to prolong the duration of the local anesthesia for a time period longer than that obtainable from the substrate without the augmenting agent.

A method and solution for perioperatively inhibiting a variety of pain and inflammation processes during arthroscopic procedures. The solution preferably includes a vasoconstrictor that exhibits alpha-adrenergic activity and one or more additional pain and inflammation inhibitory agents at dilute concentration in a physiologic carrier, such as saline or lactated Ringer's solution. The solution is applied by continuous irrigation of a wound during a surgical procedure for peripheral vasoconstriction and inhibition of pain and / or inflammation while avoiding undesirable side effects associated with systemic application of larger doses of the agents.

A knee brace (10) consisting of an upper arch (12) positioned, when worn, above the knee and a lower arch (16) positioned, when worn, below the knee, connected to means of constraint for fixing to the limb, a first upright (13) equipped in its central part with a joint (15) consisting of a pair of respective rotating elements comprising toothed wheel portions prevented from reciprocally moving in a direction perpendicular to the axis of the brace, the first upright (13) presenting a first system designed to exert adjustable pressure on the knee joint and a second system designed to compensate the deformation of the first upright (13) in exerting this pressure, the first system consisting of a first micrometric angular hinge (20) positioned on the femoral part of the first upright (13) and a second micrometric angular hinge (21) positioned on the tibial part of the same upright (13), the brace having each of the respective rotating elements rigidly connected to a respective micrometric angular hinge element, and each micrometric angular hinge which is also rigidly connected to the second compensation system which is in turn connected to a respective femoral or tibial arch of the brace (10).

Methods and formulations for inducing substantially safer local anesthesia in a patient are provided. The methods comprise administering, to a patient in need thereof, a substrate containing a local anesthetic and an effective amount of a biocompatible, biodegradable, controlled release material to safely obtain a reversible nerve blockade when implanted or injected in a patient.

Methods and compositions for inhibiting articular cartilage degradation. The compositions preferably include multiple chondroprotective agents, including at least one agent that promotes cartilage anabolic activity and at least one agent that inhibits cartilage catabolism. The compositions may also include one or more pain and inflammation inhibitory agents. The compositions may be administered systemically, such as to treat patients at risk of cartilage degradation at multiple joints, and suitably may be formulated in a carrier or delivery vehicle that is targeted to the joints. Alternatively the compositions may be injected or infused directly into the joint.

A knee brace (10) consisting of an upper arch (12) positioned, when worn, above the knee and a lower arch (16) positioned, when worn, below the knee, connected to means of constraint for fixing to the limb, a first upright (13) equipped in its central part with a joint (15) consisting of a pair of respective rotating elements comprising toothed wheel portions prevented from reciprocally moving in a direction perpendicular to the axis of the brace, the first upright (13) presenting a first system designed to exert adjustable pressure on the knee joint and a second system designed to compensate the deformation of the first upright (13) in exerting this pressure, the first system consisting of a first micrometric angular hinge (20) positioned on the femoral part of the first upright (13) and a second micrometric angular hinge (21) positioned on the tibial part of the same upright (13), the brace having each of the respective rotating elements rigidly connected to a respective micrometric angular hinge element, and each micrometric angular hinge which is also rigidly connected to the second compensation system which is in turn connected to a respective femoral or tibial arch of the brace (10).

The invention belongs to the field of health beverages, and in particular relates to a gynura procumbens compound preparation as well as a preparation method and application thereof. The gynura procumbens compound preparation is characterized by being prepared from the following raw materials in percentage by weight: 75-85% of gynura procumbens, 5-10% of barley seedlings, 3-6% of common lophatherum herb, 2-5% of frostbitten mulberry leaves, 2-4% of kudzuvine root and 1-3% of poria cocos. The preparation method of the gynura procumbens compound preparation comprises the following steps: performing weighing, drying and small fire baking on gynura procumbens, then mixing with other weighed raw materials, and crushing. The preparation disclosed by the invention is safe, healthy and natural, has various effects of treating gout in multiple ways comprehensively, can play roles in adjusting uric acid metabolism, promoting excretion of uric acid, preventing uric acid crystallization, diminishing inflammation and relieving pain, and controlling arthralgia, swelling and inflammations in an attack stage of gout, also can be used for reducing the blood lipid and blood sugar and strengthening kidney metabolism, can be used for treating both symptoms and root causes and achieving the effects of preventing and treating gout, and has the characteristics of natural compounds and natural health maintenance; and the preparation method disclosed by the invention is simple and convenient, and can be used for keeping original components of the raw materials to the greatest extent.

The invention relates to a medicinal composition used for treating human or animal dental ulcer; the medicinal composition consists of an active component, dexamethasone, one or more medicinal salts or esters thereof, vitamin B12, and one or more medicinal inactive components that are suitable for local administration to the oral cavity.

A thermal regulatory system to reduce swelling caused by trauma to a variety of tissues and limbs is provided. One or more substantially flexible, at least partially thermally conductive housing containing optionally activatable thermal regulatory medium may be coupled with one or more applicator, such as a splint, that is adapted to apply the medium housing to the tissue. Methods of therapeutically regulating tissue temperature are also provided.

A thermal regulatory system to reduce swelling caused by trauma to a variety of tissues and limbs is provided. One or more substantially flexible, at least partially thermally conductive housing containing optionally activatable thermal regulatory medium may be coupled with one or more applicator, such as a splint, that is adapted to apply the medium housing to the tissue. Methods of therapeutically regulating tissue temperature are also provided.

The present invention provides a therapy instrument for myocardial ischemia, which is combined with power circuit, generation circuit of modulation wave, shaping circuit of modulation wave, modulation circuit, constant current source circuit, stimulating electrode, CPLD carrier generation circuit, carrier shaping circuit, output intensity control circuit and MCU. The therapy instrument has characters of non-invasive, non-pain sense electrical stimulation, overcoming body adaptability etc., and can treat patient with comfortable sense. The therapy instrument can assistant treat myocardial ischemia by skin spinal cord and fastigial nucleus electrical stimulation. The therapy instrument modulates the random signal of low-frequency slow change rhythm on the MF carrier signal with special spectrum structure by method of pulse amplitude modulation, and loads LF current to human skin spinal cord and fastigial nucleus with forms of current by surface electrode. The therapy instrument can treat myocardial ischemia by improving coronary blood flow, reducing myocardial oxygen consumption, controlling pain and protecting neurogenic neuroprotection.

The invention belongs to the field of medicines, and in particular relates to a Chinese medicine composition for removing scars and a preparation method thereof. The Chinese medicine composition is prepared from the following raw materials in parts by weight: 6-12 parts of radix angelicae, 6-12 parts of the root of red-rooted salvia, 4-8 parts of centipede, 5-10 parts of dandelion, 3-8 parts of safflower carthamus, 5-10 parts of sanguisorba officinalis, 5-10 parts of pearl powder, 1-4 parts of camphor, 4-10 parts of honey and 8-15 parts of Vaseline. The Chinese medicine composition has the advantages of stable effect, rapid efficacy, fast acting, short treatment course and significant effect, and is convenient to use; and meanwhile the Chinese medicine composition has the functions in improving skin microcirculation of a wounded part, recovering the skin elasticity of the wounded part, removing pigmentation, activating blood and removing scars, detoxifying and covering, prompting granulation and removing stasis, moistening skin and the like; and furthermore, the Chinese medicine composition can be used for treating scars of various types.

A microenvironment of a biological body is controlled, and more particularly, is measured, changed, and monitored with respect to temperature, pH level, moisture and other tissue parameters of a region of the body while, optionally, administering a therapeutic agent to that region.

This invention is disclosing a pure ointment of traditional Chinese medicine which was invented to treat burn or scald, and infectious trauma, and its preparation. The ointment has solved a number of problems in the treatment of burn or scald, and infectious trauma, such as the high cost of current drugs, post-treatment scar, and unfavorable therapeutic effect. The advantages of this ointment include low cost, favorable therapeutic effect, short course, and without scar after treatment. Its formula is based on the weight of every five hundred portions of following ingredients: lithospermum, 4-10 portions, beeswax, 5-20 potions, insect-white wax, 5-20 portions, and lard, 450-486 portions.

The present invention providing a Chinese medicine ointment, particularly the one for curing herpes zoster and the preparation thereof, is directed to a drug combination of antibiotic and antiviral drug with the following disadvantages: a slow effect, an easy entry to the outbreak period, a long treatment time, a high cost of treatment and the like. The ointment with hedgehog skin and sesame oil as raw materials has properties in a simple prescription and production, a low cost, healing fast and a high cure rate without toxic and side effect.

A torso compression medical device allows selectively applied compressive torso support to alleviate chest pain. The device includes a flexible band of material having a width of at least several inches and a length sufficient to extend substantially around the person's torso, with handles on ends of the band positioned adjacent the person's hands. The handles can be grasped by the person and biased to selectively generate compression forces on the person's torso from wrapping tension on the band of material. Cushions on the band distribute forces from the tensioned band onto the person's torso. Related methods of use are disclosed, including wearing the device as a garment.

The invention belongs to the technical field of traditional Chinese medicaments, and provides a traditional Chinese medicament for treating digestive tract cancers. The traditional Chinese medicament is prepared from the following components by weight: 20-40g of purpurea halitium, 20-40g of borneol, 50-70g of aconite, 50-70g of arisaema cum bile, 50-70g of potassium nitrate and 10-15g of nux vomica. The traditional Chinese medicament has the advantages of exact curative effect, low relapse rate and high safety.

Apparatuses and methods for generating therapeutic compressed acoustic waves (e.g., shock waves) with an improved acoustic wavefront. In the apparatuses, a housing is defined by a chamber and a shockwave outlet, the chamber is configured to be filed with liquid, a plurality of electrodes defining one or more spark gaps and an acoustic reflector can disposed in the chamber, and a pulse generation system configured to apply voltage pulses to the electrodes at a rate of between 10 Hz and 5 MHz. The improved acoustic wavefront is achieved via a free-form acoustic reflector and / or a stable spark gap location. The free-form acoustic reflector is designed according to a disclosed method including iterating reflector shape using spline interpolation based on defined variables. Additionally, a stable spark gap location is achieved via a single servomotor that adjusts both electrodes simultaneously.

A topical anesthetic composition comprising benzocaine, pharmaceutically acceptable salt thereof, amide thereof and / or ester thereof; tetracaine and / or pharmaceutically acceptable salt thereof; ethanol; polyethylene glycol; propylene glycol; water; and benzyl alcohol is provided. Also provided is method for dispensing the above topical anesthetic composition to a desired site such by spraying the topical anesthetic from a pump actuated metered dose spray device. The topical anesthetic composition can also be administered subgingivally with a syringe and applicator tip. A product comprising the above topical anesthetic spray composition contained in a pump actuated metered dose spray device.

The invention relates to the field of medicines, and in particular relates to a medicinal magnetic plaster for treating tumors. The plaster comprises a medical adhesive tape, more than 20 traditional Chinese medicines, a medicinal magnetic layer made of a permanent magnet or magnetic powder, a protective layer and the like. The medicinal magnetic plaster has the effects of dredging collaterals, removing stasis, eliminating phlegm, promoting diuresis, removing toxicity to relieve pain, relieving and eliminating mass and the like to inhibit tumor growth, changing shapes of cancer cells, inducing apoptosis of tumor cells, gradually reducing tumors, eliminating inflammation of vascular wall, controlling transfer of pain signals, improving local micro-circulation, controlling spread and pain of medium or advanced cancer, and the like; the plaster can be divided in different magnetic field strength, different shapes and different specification models; when the plaster is used, the required specification model is selected, the protective layer is peeled off, the medicinal magnetic layer of the stagnation-eliminating plaster is directly adhered to the meridian skin, corresponding acupoint or the Shenque acupoint in a range of the focus area, and the plaster is fixed by the medical adhesive tape; different parts can be adhered by multiple plasters at the same time, and each plaster is used for 1-2 days.