119results about How to "Control degradation" patented technology

An electrode with three-dimensional capabilities for detection and control of brain state changes of a subject. The electrode includes a disk portion having an upper surface and a lower surface, and a shaft portion secured to and extending perpendicularly outwardly from the lower surface of the disk portion; the shaft portion having an outer surface. The disk portion and shaft portion may include one or more recording or stimulating contact surfaces structured to operatively interact with the brain of a subject. Insulating material isolates each of the recording or stimulating contact surfaces from each other. At least one conductor operatively and separately connect each of the recording or stimulating contact surfaces in communication with external apparatus. The disk portion and shaft portion are structured relative to each other to operatively provide support and anchoring for each other while providing three-dimensional capabilities for detection and control of brain state changes of a subject. Modified embodiments include insertible/retractable electrode wires, both contained in channels and sheathed in axially displaceable cannulae; activating mechanisms for inserting/retracting the electrode wires and/or cannulae; and multiple shaft portions.

Methods and compositions for inhibiting articular cartilage degradation. The compositions preferably include multiple chondroprotective agents, including at least one agent that promotes cartilage anabolic activity and at least one agent that inhibits cartilage catabolism. The compositions may also include one or more pain and inflammation inhibitory agents. The compositions may be administered systemically, such as to treat patients at risk of cartilage degradation at multiple joints, and suitably may be formulated in a carrier or delivery vehicle that is targeted to the joints. Alternatively the compositions may be injected or infused directly into the joint.

In an autonomous system, the method for charging a power storage element from a generator comprises temperature measurement, with switching from a first charging mode to a second charging mode in which the voltage is regulated by the temperature. The first charging mode is charging at regulated current to a maximum current value which is a function of the state of charge of the power storage element and of the temperature of the power storage element. Switching is performed when the voltage at the terminals of the power storage element reaches a preset threshold value, itself a function of the value of the current and temperature of the power storage element.

When attempting to make a lithium ion-switching device such as a high-efficiency, all-solid state, thin film battery the choice of carrier substrate is all important. As such a substrate must withstand a high temperature under an oxidising atmosphere to crystallise certain layers making up the device, the substrate should not oxidise thereby ruling out most metals. The invention now describes a class of ternary alloys of which the oxidation rate is limited and that are useable to produce thin film batteries on. At least one element with a high affinity to oxygen (Al, Mg, Zn or Si) is present in the alloy. The other two metallic elements reduce the growth of the oxide of this first element. In addition the thus formed oxide scale turns out to be an effective barrier to lithium. Surprisingly, the scale shows nanoscopic voids that allow for sufficient electrical contact with the device layers, thereby eliminating the need for a separate current collector. As the ternary alloy can be made in a flexible foil, it can advantageously be used in a roll-to-roll process.

An inverse dispersion fiber having a large effective area and a transmission system that incorporates the fiber for providing dispersion and dispersion slope compensation in a transmission fiber. The large-effective-area inverse dispersion optical fiber (IDF) has a negative dispersion and a negative dispersion slope. The effective area, A_eff, of the IDF preferably is greater than approximately 31 micrometers squared (μm²) at a transmission wavelength of approximately 1550 nm. The large-effective-area IDF is suitable for use with super-large-effective-area (SLA) transmission fiber for compensating dispersion in the SLA transmission fiber while reducing nonlinear effects between wavelength channels and cabling loss, which is especially advantageous in transoceanic and long-haul terrestrial systems. These nonlinear effects are inversely related to the effective area of the fiber (i.e., nonlinearities˜1/A_eff). Thus, an increase in the effective area of the fiber translates into a decrease in nonlinear interactions, which increases bandwidth capabilities and limits signal degradation. Furthermore, the large-effective-area IDF of the present invention has very desirable transmission properties. The present invention also provides a transmission system comprising at least one of the large-effective-area IDF optical fibers of the present invention. Furthermore, A_eff can be made large without having to increase the ratio, R_a, of the diameter of the core to the diameter of the trench region.

A modified water-immiscible solvent useful in the extraction of acetic acid from aqueous streams is a substantially pure mixture of isomers of highly branched di-alkyl amines. This solvent is substantially devoid of mono-alkyl amines and alcohols. Solvent mixtures formed of such a modified solvent with a desired cosolvent, preferably a low boiling hydrocarbon which forms an azeotrope with water are useful in the extraction of acetic acid from aqueous gaseous streams. An anaerobic microbial fermentation process for the production of acetic acid employs such solvents, under conditions which limit amide formation by the solvent and thus increase the efficiency of acetic acid recovery. Methods for the direct extraction of acetic acid and the extractive fermentation of acetic acid also employ the modified solvents and increase efficiency of acetic acid production. Such increases in efficiency are also obtained where the energy source for the microbial fermentation contains carbon dioxide and the method includes a carbon dioxide stripping step prior to extraction of acetic acid in solvent.

Device that can be used in an enhanced oil recovery method by injection of a solution of water soluble polymer and brine having a viscosity below 1000 cps that includes a mixer, and preferably a static mixer, capable of homogenizing the solution on-line; a device capable of measuring the viscosity of the homogenized solution, continuously, downstream of the solution injection pump, at a pressure below or equal to 250 bars, and preferably between 50 and 250 bars, and at a temperature below or equal to 120° C., and preferably between 40 and 120° C., by measuring a pressure drop in a calibrated tube, at a constant rate of flow.

An apparatus for controlling the injection pressure of an aqueous polymer solution in a subsea oil wellhead, includes a linear pressure reducer in the form of a tube connected in series to the main injection line that is capable of absorbing the majority of the pressure drop and a choke that is capable of being regulated in order to enable a pressure control between 0 and 10 bar. Also, a process of offshore enhanced oil recovery by injection of an aqueous polymer solution uses the apparatus.

An electronic device detects a discontinuous figure in an old-new connection portion between old and new data and performs shape correction so as to restore the continuous figure. In this case, only the old data is corrected. Particular shape correction methods are as follows: (a) only the old-data side shape point P1 in the old-new connection portion is moved to match the new-data side shape point SP1; (b) other shape points P2 to P5 are moved in parallel by the same amount as that of movement of the shape point P1 in the old-new connection portion; and (c) among the old-data side shape points P1 to P5, the farthest shape point P5 from the shape point P1 in the old-new connection portion is not moved as a reference, and the other shape points P1 to P4 are moved in accordance with distance from the farthest shape point P5.

PCT No. PCT/JP97/04687 Sec. 371 Date Aug. 18, 1998 Sec. 102(e) Date Aug. 18, 1998 PCT Filed Dec. 18, 1997 PCT Pub. No. WO98/27573 PCT Pub. Date Jun. 25, 1998A shadow mask opposed to a phosphor screen has a substantially rectangular effective surface (30) where slit-like apertures are formed. The apertures are disposed so as to constitute a plurality of aperture rows which extend in parallel with the short axis of the effective surface and are disposed in the long axis of the effective surface. Each of the aperture rows includes a plurality of aperture, and bridges (38) positioned between any adjacent pair of the apertures. The width B of the bridges in the lengthwise direction of the aperture rows, positioned an intermediate between the short axis of the effective surface and a short side edge thereof is greater than that of the bridges positioned at a peripheral portion of the effective surface.

In a liquid crystal display device which is constructed by sealing a liquid crystal having spontaneous polarization in an active matrix panel including a coloring member and displays an image on a frame by frame basis by repeating a data writing process and a data erasing process for the active matrix panel, the frequency in the data writing process is set at least twice higher than a frame frequency and the data writing process and the data erasing process are completed within one frame time so that time taken for transmission of light through the coloring member is not more than a half of one frame time. The coloring member is in a non-light-transmitting state during a period of not shorter than a half of one frame, and the blurred outline section of a moving image is reduced.

An image processing apparatus includes a detection unit configured to detect at least one identical object or at least one object of an identical type from images captured by a plurality of imaging apparatuses, a selection unit configured to select at least one object from among at least one detected object based on color information of each object, and a determination unit configured to determine color correction information related to a plurality of the imaging apparatuses based on color information of at least one selected object. The image processing apparatus enables restricting the degradation of the color matching accuracy.

The invention relates to a preparation method of biapenem aseptic powder. Specifically, in a preparation process of a biapenem crude product, an alkaline substance of 2,6-lutidine is used so that post-reaction treatment is simple and a yield is high. In a preparation process of biapenem aseptic powder, acetic acid is utilized for adjustment of a pH value of water so that dissolvability and stability of biapenem in water are improved. Biapenem aseptic powder prepared through the preparation method has a high yield and controllable quality.

The invention discloses a ternary complex nanodrug, a preparation method and application thereof in preparation of a light controlled release nano-delivery system. The ternary complex nanodrug comprises a thioketal bond crosslinked low molecular weight PEI-based polymer, a hyaluronic acid polymer attached with a photosensitizer, and a nucleic acid drug. The photosensitizer contained in the complexcan generate reactive oxygen species (ROS) under the control of exogenous red light, realize photochemical internalization (PCI) mediated lysosome escape and photopromoted polymer degradation, thus finally realizing the purposes of reducing the toxic and side effects of materials, improving the transfection efficiency, and enhancing the tumor gene therapeutic effect.

The invention relates to a diabetes pathological model based on cell assembly technology and application thereof in high content drug screening. Adipose-derived stem cells and simulated extracellular matrix material are assembled to form a cell-containing three-dimensional structure with certain porosity; the inducing differentiation condition is controlled to enable the adipose-derived stem cells on the surface of the inner passage of the three-dimensional structure to differentiate into endothelial cells and to enable the adipose-derived stem cells inside the matrix material to differentiate into fat cells; and pancreas islet separated out from the body of an animal is directly assembled in the gaps of the three-dimensional structure. The system model is excited for a long time by high-concentration dextrose, fatty acid insulin, TNF or cytokine secretion of fat cells and the like so as to induce the system model to produce pathology and symptom of diabetes. The drug to be tested is put into a culture system, and by detecting the level of the relevant markers of the model under normal condition and pathological condition, the pharmacological activity of the drug to be tested can be analyzed and thereby high content screening can be carried out to the drug.

The invention relates to preparation of hollow capsules, specifically to marine animal fish skin gelatin hollow capsules and a preparation method thereof. The fish skin gelatin hollow capsules comprise the following four components by weight, 15-50% of fish skin gelatin, 0.1-30% of a plasticizer, 0.001-10% of a surfactant and 40-80% of water. According to the present invention, the adopted fish skin gelatin has characteristics of good film formation, good safety, good biocompatibility and good biodegradability, is a high quality protein resource, and has effects of human immunity increase and memory enhancement; the preparation method has characteristics of simple operation, easily available raw materials and significantly reduced hollow capsule production cost; and the obtained hollow capsules do not have the excessive heavy metal problem, do not contain hydroxybenzoate esters and other harmful preservatives, and do not adopt ethylene oxide and other sterilization processes.

The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water, a sodium containing concentrate, and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consists of powder components comprising glucose, at least one dry acid and at least one magnesium salt, and optionally potassium salt, and calcium salt. According to the invention said glucose and said at least one magnesium salt, are present as anhydrous components in said dialysis acid precursor composition.

A method for producing chitosan oligosaccharides coupled with enzymatic degradation of chitosan and membrane separation is characterized in that the production process is as follows: (1) preparing chitosan oligosaccharides by enzymatic degradation of chitosan; (2) adopting hollow fiber or flat ultra- Combine the filter with the degradation reaction to separate the active oligosaccharides in situ; (3) filter the ultrafiltrate with a nanofilter to separate high-concentration active chitosan oligosaccharides. The invention realizes the integration of reaction and separation, and prevents secondary degradation of active oligosaccharides. Since the process realizes continuous operation, the degrading enzyme can be used continuously, the yield is improved, the cost is reduced, and it is beneficial to realize industrialization.