The utility model provides a kind of high stability linear guide rail mounting base, the high stability linear guide rail mounting base includes linear guide rail body, the linear guide rail body is provided with sliding block, the linear guide rail body bottom is provided with guide rail mounting base, the both sides of the guide rail mounting base are provided with fixed slot, and one locating groove is provided on the side wall in the fixed slot.The high stability linear guide rail mounting base provided by the utility model provides independent, stable support carrier for linear guide rail, avoids the problem of uneven installation surface caused by direct contact between guide rail and equipment rack, improves overall installation reference accuracy, fixed slot forms preliminary horizontal limit for guide rail, prevents left and right deviation during guide rail installation;Positioning groove further accurately clamps guide rail, so that guide rail and base form firm positioning cooperation, reduce the micro-displacement of guide rail during the operation of sliding block, maintain transmission clearance stable, improve stability, improve long-term operation accuracy of equipment.