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61results about How to "Limit their usefulness" patented technology

Multifocal imaging systems and method

In the systems and methods of the present invention a multifocal multiphoton imaging system has a signal to noise ratio (SNR) that is reduced by over an order of magnitude at imaging depth equal to twice the mean free path scattering length of the specimen. An MMM system based on an area detector such as a multianode photomultiplier tube (MAPMT) that is optimized for high-speed tissue imaging. The specimen is raster-scanned with an array of excitation light beams. The emission photons from the array of excitation foci are collected simultaneously by a MAPMT and the signals from each anode are detected using high sensitivity, low noise single photon counting circuits. An image is formed by the temporal encoding of the integrated signal with a raster scanning pattern. A deconvolution procedure taking account of the spatial distribution and the raster temporal encoding of collected photons can be used to improve decay coefficient. We demonstrate MAPMT-based MMM can provide significantly better contrast than CCD-based existing systems.
Owner:MASSACHUSETTS INST OF TECH

Phased array metamaterial antenna system

An efficient, low-loss, low sidelobe, high dynamic range phased-array radar antenna system is disclosed that uses metamaterials, which are manmade composite materials having a negative index of refraction, to create a biconcave lens architecture (instead of the aforementioned biconvex lens) for focusing the microwaves transmitted by the antenna. Accordingly, the sidelobes of the antenna are reduced. Attenuation across microstrip transmission lines may be reduced by using low loss transmission lines that are suspended above a ground plane a predetermined distance in a way such they are not in contact with a solid substrate. By suspending the microstrip transmission lines in this manner, dielectric signal loss is reduced significantly, thus resulting in a less-attenuated signal at its destination.
Owner:LUCENT TECH INC

Read Ahead Tiered Local and Cloud Storage System and Method Thereof

A high tier storage area stores a stub file and a lower tier cloud storage area stores the file corresponding to the stub file. When a client apparatus requests segments of the file from the high tier storage area, reference is made to the stub file to determine a predicted non-sequential pattern of requests to the segments by the client apparatus. The high tier storage area follows the predicted non-sequential pattern of requests to retrieve the segments of the file from the cloud prior to the client apparatus actually requesting the segments. As such, the file may be efficiently provided to the client apparatus while also efficiently storing the file on the lower tier cloud storage area.
Owner:HITACHI VANTARA LLC

Secure authentication and payment system

A transaction and payment and processing system securely conducts transactions over the public telephone network. The transactions may be between and among entities of any type such as individuals, merchants, utilities, banks, etc. Nothing more than access to a telephone is required after initial registration of a user.
Owner:ALIASWIRE

Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation

A method and solution for perioperatively inhibiting a variety of pain and inflammation processes during arthroscopic procedures. The solution preferably includes a vasoconstrictor that demonstrates substantial agonist activity at alpha adrenergic receptors and that is selected for peripheral (local) vasoconstriction and one or more additional pain and inflammation inhibitory agents at dilute concentration in a physiologic carrier, such as saline or lactated Ringer's solution. The solution is applied by continuous irrigation of a wound during a surgical procedure for peripheral vasoconstriction and inhibition of pain and / or inflammation while avoiding undesirable side effects associated with systemic application of larger doses of the agents.
Owner:OMEROS CORP

Irrigation solution and method for inhibition of pain, inflammation, spasm and restenosis

A method and solution for perioperatively inhibiting a variety of pain, inflammation, spasm and restenosis processes resulting from cardiovascular or general surgical, therapeutic and diagnostic procedures. The solution preferably includes multiple pain and inflammation inhibitory agents, including at least one local anesthetic agent, and spasm inhibitory agents at dilute concentration in a physiologic carrier, such as saline or lactated Ringer's solution. Specific preferred embodiments of the solution of the present invention for use in cardiovascular and general vascular procedures also include anti-restenosis agents.
Owner:OMEROS CORP

Compositions and methods for systemic inhibition of cartilage degradation

Methods and compositions for inhibiting articular cartilage degradation. The compositions preferably include multiple chondroprotective agents, including at least one agent that promotes cartilage anabolic activity and at least one agent that inhibits cartilage catabolism. The compositions may also include one or more pain and inflammation inhibitory agents. The compositions may be administered systemically, such as to treat patients at risk of cartilage degradation at multiple joints, and suitably may be formulated in a carrier or delivery vehicle that is targeted to the joints. Alternatively the compositions may be injected or infused directly into the joint.
Owner:OMEROS CORP

Pharmaceutical compositions

A method and solution for perioperatively inhibiting a variety of pain and inflammation processes at wounds from general surgical procedures including oral / dental procedures. The solution preferably includes multiple pain and inflammation inhibitory at dilute concentration in a physiologic carrier, such as saline or lactated Ringer's solution. The solution is applied by continuous irrigation of a wound during a surgical procedure for preemptive inhibition of pain and while avoiding undesirable side effects associated with oral, intramuscular, subcutaneous or intravenous application of larger doses of the agents. One preferred solution to inhibit pain and inflammation includes a serotonin2 antagonist, a serotonin3 antagonist, a histamine antagonist, a serotonin agonist, a cyclooxygenase inhibitor, a neurokinin1 antagonist, a neurokinin2 antagonist, a purinoceptor antagonist, an ATP-sensitive potassium channel opener, a calcium channel antagonist, a bradykinin1 antagonist, a bradykinin2 antagonist and a mu-opioid agonist.
Owner:OMEROS CORP

Radiation therapy system

A radiation therapy System comprises a magnetic resonance imaging (MRI) apparatus and a linear accelerator capable of generating a beam of radiation. The linear accelerator is immersed in and oriented with respect to the MRI magnetic field to expose the linear accelerator to magnetic force that directs particles therein along a central axis thereof.
Owner:ALBERTA HEALTH SERVICES

Surgical irrigation solution and method for inhibition of pain and inflammation

A method and solution for perioperatively inhibiting a variety of pain and inflammation processes at wounds from general surgical procedures including oral / dental procedures. The solution preferably includes multiple pain and inflammation inhibitory at dilute concentration in a physiologic carrier, such as saline or lactated Ringer's solution. The solution is applied by continuous irrigation of a wound during a surgical procedure for preemptive inhibition of pain and while avoiding undesirable side effects associated with oral, intramuscular, subcutaneous or intravenous application of larger doses of the agents. One preferred solution to inhibit pain and inflammation includes a serotonin2 antagonist, a serotonin3 antagonist, a histamine antagonist, a serotonin agonist, a cyclooxygenase inhibitor, a neurokinin1 antagonist, a neurokinin2 antagonist, a purinoceptor antagonist, an ATP-sensitive potassium channel opener, a calcium channel antagonist, a bradykinin1 antagonist, a bradykinin2 antagonist and a mu -opioid agonist.
Owner:OMEROS CORP

Switchable imaging polarimeter and method

A polarimeter and method of polarizing incoming light includes an optical assembly, a first adjustable circular retarder that rotates the polarization content of incoming light, a polarization beam splitter that receives light from the adjustable circular retarder and polarizing the light into a first portion of light having a first polarization and a second portion of light having a second polarization. The first portion of light is directed to a focal plane and the second portion of light is directed to the optical assembly. The optical assembly is switchable between a polarizing mode of operation in which the first portion of light is viewable at the focal plane in absence of the second portion of light and an imaging mode of operation in which the first portion of light and the second portion of light are viewable at the focal plane.
Owner:RAYTHEON CO

Method of inhibition of pain and inflammation during surgery comprising administration of soluble TNF receptors

A method and solution for perioperatively inhibiting a variety of pain and inflammation processes at wounds from general surgical procedures including oral / dental procedures. The solution preferably includes at least one tumor necrosis factor (TNF) soluble receptor at dilute concentration in a physiologic carrier, such as saline or lactated Ringer's solution. The solution is applied locally and perioperatively to a surgical site during a surgical procedure for preemptive inhibition of pain and while avoiding undesirable side effects associated with oral, intramuscular, subcutaneous or intravenous application of larger doses of the agents.
Owner:OMEROS CORP

Program Test System

An improved automated software testing system provides the ability to generate and reuse test cases over multiple platforms. Keywords and natural language are used in test case creation, simplifying the process for non-technical business users. Business users can write test cases without scripts. Test cases can be generated even before the application to be tested is available. Data substitution provides ability for test cases to adapt to changing data. Abstraction allows use of all third-party and custom software test tools to be incorporated. Persistent data handling allows capture of data generated during test execution for later use. Testing can be performed entirely automatically or can incorporate some manual interaction. Test results, screen captures of the system tested, along with environment and machine variables are saved in results logs for later review.
Owner:SYSTWARE

Dual action locking pliers

ActiveUS7389714B1Dexterity limitedHand strength limitedPliersGrip forceDual action
A locking pliers tool with an improved dual action driver handle comprising two intersecting handles and interacting jaws. When the user grips the handle forward the resultant force produces a locking action. Conversely, when a rearward gripping force is initiated, the tool releases its grip on the object. A limited amount of energy on the inventive handle produces free movement of the handle and gripping mechanism to lock or release. The system operates with a handle and stationary jaw in conjunction with a second pivotally secured jaw and internal adjustment bolt. A second lever handle rests against the adjustment bolt. An over center toggle link connects the second lever handle to the pivotally secured second jaw. A tension spring interconnects the first handle and the pivotally secured second jaw.
Owner:HEAGERTY MICHAEL

Controlled flow polymer blends and products including the same

InactiveUS20080045102A1Easy to manufactureFacilitating downstream storageLaminationLamination apparatusPolymer scienceDelivery system
The present invention is directed to polymer blends having controlled flow properties. The polymer blends can be useful in various applications including bonding systems and additive delivery systems, which can provide durable binding and / or delivery and / or affixing of additives. The polymer blends can include at least two different components, at least one being a polymer component having a higher molecular than the other of the components. When heated to an activating temperature, the resultant blend exhibits desirable flow or wet out properties without applied pressure. Despite the controlled flow properties, the blends do not exhibit blocking or fusing properties typically associated with high flow polymer materials.
Owner:MISSING OCTAVE INSIGHTS

Diagnositic Agent for Malignant Melanoma

An object of the present invention is to provide a novel and clinically useful diagnostic agent for malignant melanoma. The present invention provides a diagnostic agent for malignant melanoma, which comprises an antibody against GPC3, or a probe or a primer capable of detecting GPC3 expression.
Owner:LSIP

Doped nanoparticle-based semiconductor junction

A doped semiconductor junction for use in an electronic device and a method for making such junction is disclosed. The junction includes a first polycrystalline semiconductor layer doped with donors or acceptors over a substrate such that the first doped semiconductor layer has a first polarity, the first layer including fused semiconductor nanoparticles; and a second layer in contact with the first semiconductor layer over a substrate to form the semiconductor junction.
Owner:NANOCO TECH LTD

Method of monitoring the condition of a wind turbine

A method of monitoring the condition of a wind turbine. The method includes the steps of selecting a plurality of measurable parameters indicative of the operational state of the wind turbine; recording measures of a variable indicative of the condition of the wind turbine during a period of normal operation thereof, and deriving corresponding values of a characteristic quantity from said measures; recording measures of the parameters during the same period; identifying a correlation between the characteristic quantity and at least one correlated parameter; and from said correlation, defining the expected value of the characteristic quantity as a target function that is a function of said at least one correlated parameter.
Owner:GE RENEWABLE TECH WIND BV

Irrigation solution and method for inhibition of pain and inflammation

A method and solution for perioperatively inhibiting a variety of pain and inflammation processes at wounds from general surgical procedures including oral / dental procedures. The solution preferably includes at least one pharmacological agent that is a soluble receptor tyrosine kinase, and optionally additional multiple pain and inflammation inhibitory agents at dilute concentration in a physiologic carrier, such as saline or lactated Ringer's solution. The solution is applied by continuous irrigation of a wound during a surgical procedure for preemptive inhibition of pain and while avoiding undesirable side effects associated with oral, intramuscular, subcutaneous or intravenous application of larger doses of the agents.
Owner:OMEROS CORP

Multifocal imaging systems and method

In the systems and methods of the present invention a multifocal multiphoton imaging system has a signal to noise ratio (SNR) that is reduced by over an order of magnitude at imaging depth equal to twice the mean free path scattering length of the specimen. An MMM system based on an area detector such as a multianode photomultiplier tube (MAPMT) that is optimized for high-speed tissue imaging. The specimen is raster-scanned with an array of excitation light beams. The emission photons from the array of excitation foci are collected simultaneously by a MAPMT and the signals from each anode are detected using high sensitivity, low noise single photon counting circuits. An image is formed by the temporal encoding of the integrated signal with a raster scanning pattern. A deconvolution procedure taking account of the spatial distribution and the raster temporal encoding of collected photons can be used to improve decay coefficient. We demonstrate MAPMT-based MMM can provide significantly better contrast than CCD-based existing systems.
Owner:MASSACHUSETTS INST OF TECH

Stabilized solvent system for cleaning and drying

This invention relates to improved stabilizing compositions for n-propyl bromide. More particularly, the cleaning composition includes about 0.1 to 5% Butylene oxide, about 0.1 to 5.0% t-butanol, about 0.1 to 5% acetonitrile, about 0.1 to 5% nitromethane; and the remainder n-propyl bromide. These mixtures are useful as cleaning solvents for the electronic, aerospace, and general manufacturing industries, especially in the area of vapor degreasing.
Owner:POLY SYST USA

Doped nanoparticle semiconductor charge transport layer

A method is disclosed for making a doped semiconductor transport layer for use in an electronic device comprising: growing in-situ doped semiconductor nanoparticles in a colloidal solution; depositing the in-situ doped semiconductor nanoparticles on a surface; and annealing the deposited in-situ doped semiconductor nanoparticles so that the organic ligands boil off the surface of the in-situ doped semiconductor nanoparticles.
Owner:EASTMAN KODAK CO

Doped nanoparticle semiconductor charge transport layer

A method is disclosed for making a doped semiconductor transport layer for use in an electronic device comprising: growing in-situ doped semiconductor nanoparticles in a colloidal solution; depositing the in-situ doped semiconductor nanoparticles on a surface; and annealing the deposited in-situ doped semiconductor nanoparticles so that the organic ligands boil off the surface of the in-situ doped semiconductor nanoparticles.
Owner:EASTMAN KODAK CO

Magnetic Drive System and Method

ActiveUS20140333166A1Limit their usefulnessGreater understanding of science and magnetismPermanent-magnet clutches/brakesDynamo-electric brake controlMagnetEngineering
A magnetic coupling device for communicating continuous rotational or linear motion through a magnetic coupling of magnetic forces communicated from magnets operatively positioned on an oscillation assembly and a rotation assembly in positions sufficiently proximate to form the magnetic coupling. Employed to communicate an output force in a rotational direction from an input linear force communicated from a powered oscillation assembly, the magnetic force of the magnet communicating the force compresses the volume of ellipsoidal-like magnetic fields of the coupling alternately in unlike polar domains, to induce a smooth, blended polar continuity and communicate a continuous 360 degree rotational force to a rotation assembly operatively engaged with the magnetic coupling. The input force may be reversed to induce a continuous linear motion of a reciprocating assembly.
Owner:GARDNER JAMES JOSEPH

Gate stack metrology

ActiveUS8774359B1Fast and simple to determineMore surface sensitivityMaterial analysis using radiation diffractionMetrologyX-ray
An x-ray photoelectron spectroscopy apparatus for measuring film stack characteristics, of the type having an x-ray source and an x-ray photoelectron spectroscopy module coupled to a contiguous vacuum environment, including an ultraviolet source and an ultraviolet photoelectron spectroscopy module coupled to the vacuum environment.
Owner:KLA TENCOR TECH CORP

Multifocal imaging systems and method

In the systems and methods of the present invention a multifocal multiphoton imaging system has a signal to noise ratio (SNR) that is reduced by over an order of magnitude at imaging depth equal to twice the mean free path scattering length of the specimen. An MMM system based on an area detector such as a multianode photomultiplier tube (MAPMT) that is optimized for high-speed tissue imaging. The specimen is raster-scanned with an array of excitation light beams. The emission photons from the array of excitation foci are collected simultaneously by a MAPMT and the signals from each anode are detected using high sensitivity, low noise single photon counting circuits. An image is formed by the temporal encoding of the integrated signal with a raster scanning pattern. A deconvolution procedure taking account of the spatial distribution and the raster temporal encoding of collected photons can be used to improve decay coefficient. We demonstrate MAPMT-based MMM can provide significantly better contrast than CCD-based existing systems.
Owner:MASSACHUSETTS INST OF TECH
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