33 results about "Propyl bromide" patented technology

The invention discloses a stable curing material of high-expansibility heavy metal polluted clay and a preparation method of the stable curing material, belongs to the technical field of engineering materials and environmental engineering, and is used for solving the technical problems that in the prior art, all curing components in the stable curing material are poor in binding property and poor in adsorbability to polluted heavy metal elements. The preparation method comprises the following steps: synthesizing an intermediate A from composite carbide slag pellets, a modified adhesive, an alkaline excitation material, dead burned magnesium oxide, metakaolin, polyvinyl alcohol, chlorocyclopropane and methyltrimethoxysilane, reacting allyl bromide with methyl trichlorosilane to obtain allyl chlorosilane, reacting the intermediate A with allyl chlorosilane to obtain the modified calcium carbide slag pellets. The modified adhesive with high viscosity and strong adsorbability is obtained, the fly ash, the modifier and the carbide slag are mixed, and high-strength and high-stability composite carbide slag pellets are obtained through spheroidizing treatment and high-temperature calcination, so that the prepared stable curing material has the advantages of being excellent in adsorption curing performance and good in overall stability.

The invention belongs to the technical field of molecular sieve synthesis, and discloses a preparation method of a TS-1 molecular sieve for phenol hydroxylation, which comprises the following steps: dropwise adding tetraethyl orthosilicate into an aqueous solution containing tetrapropylammonium hydroxide; after clarification, dropwise adding a solution containing tetrabutyl titanate and isopropanol into the solution; carrying out hydrothermal crystallization, centrifugation, drying and calcination; the preparation method comprises the following steps: adding silica gel into an aqueous solution of tetrapropylammonium bromide and ethanolamine; dropwise adding a solution containing tetrabutyl titanate and isopropanol into the solution; adding a seed crystal; carrying out hydrothermal crystallization, centrifugation, drying and calcination; dissolving in an aqueous solution of tetrapropylammonium bromide and ethanolamine; and carrying out hydrothermal crystallization, centrifugation, drying and calcination. The method is low in cost and simple to operate, a large number of mesopores are formed in the molecular sieve, the diffusion mass transfer rate is increased, the content of hexa-coordinated titanium is greatly increased, and the catalyst has good catalytic activity in 1-hexene epoxidation, cyclohexene epoxidation, propylene epoxidation and phenol hydroxylation reactions.

The invention belongs to the technical field of chemical engineering, and discloses a cooling agent N, 2, 3-trimethyl-2-isopropyl butyramide and a synthesis method and application thereof, and the synthesis method comprises the following steps: adding propionitrile and isopropyl bromide into a reaction kettle, and reacting under the low-temperature liquid ammonia condition of-30-50 DEG C to obtain an intermediate DIPPN; carrying out purification and distillation on the intermediate DIPPN; reacting the purified and distilled intermediate DIPPN with dimethyl polyphosphate at the temperature of 100-140 DEG C, neutralizing with acid, separating, and filtering to obtain a crude product; the crude product is crystallized and dried, and the cooling agent N, 2, 3-trimethyl-2-isopropyl butyramide is obtained; the problem of low yield in the prior art is solved, and the problem of high acid value of amidation of methanol and concentrated sulfuric acid as a catalyst in the prior art is also solved.

The invention relates to the field of oilfield chemistry, and relates to a composite clean fracturing fluid for compact oil and gas reservoir fracturing and a fracture water plugging method. The composite clean fracturing fluid is prepared by compounding the following components in percentage by weight: 0.005 to 0.03 percent of nano particles, 0.5 to 3 percent of a viscoelastic surfactant, 0.5 to 2 percent of sodium p-toluenesulfonate and 94.97 to 98.995 percent of water. Wherein the nano particles are hydrophobic fluorine modified nano silicon dioxide, and the viscoelastic surfactant is octadecyl dimethyl hydroxypropyl ammonium bromide synthesized by N, N-dimethyl propanolamine and long-chain alkyl bromide. The composite clean fracturing fluid injection process is used for compact oil and gas reservoirs. The composite clean fracturing fluid has dual effects of fracturing and filtration loss reduction, and has higher shear resistance and viscoelasticity, and the used nanoparticles are prepared by a simple process, so that the composite clean fracturing fluid is beneficial to industrial popularization.

The invention provides a novel method for preparing an intermediate compound of aromatic sesquiterpenes Commiphoranes C-D. The method comprises the following steps: substituting the ortho-position of a compound 1 with iodine through n-butyllithium and diiodoethane to obtain a compound 2; removing methoxyl by using boron tribromide to obtain a compound 3; performing nucleophilic substitution on 3-allyl bromide and potassium carbonate to synthesize a compound 4; carrying out Grignard reaction to obtain a compound 5; oxidizing into a compound 6 through a Dess-Martin oxidizing agent; finally, (CH3Si) 3SiH and triethyl boron are subjected to intramolecular free radical series cyclization, so that synthesis of an aromatic sesquiterpene Commiphoranes C-D intermediate compound is successfully completed, sufficient preparation is made for follow-up total synthesis of the natural product, key intramolecular free radical series cyclization has the capacity of efficiently constructing a polycyclic system, and the synthesis process is simple and convenient. According to the preparation method, the defects of expensive reagents, long 14-step linear synthesis route, low yield and the like in the existing synthesis route are overcome; the popularization potential is high.

The invention discloses a method for preparing isopentenyl indole alkaloid Debromolustramine B. The isopentenyl indole alkaloid Debromolustramine B belongs to the technical field of organic synthesis, an o-bromo aniline aldehyde compound is used as an initial raw material, and on the basis of novel chiral p-toluene sulfinyl guidance, cheap copper catalysis amido alpha-position arylation and 3, 3-dimethyl allyl bromide cyclization reaction, the isopentenyl indole alkaloid Debromolustramine B is synthesized, and the isopentenyl indole alkaloid Debromolustramine B is obtained. According to the present invention, the key aryl quaternary carbon chiral center in the isopentenyl indole alkaloid Debomolustramine B is constructed, and the isopentenyl indole alkaloid Debomolustramine B with the butyrylcholine esterase inhibition activity is prepared through the subsequent series of chemical conversion, such that the material basis is provided for the further research of the natural product Debomolustramine B and the analogue thereof. The method has the advantages that the reaction conditions are mild, the cheap metal copper is used as the catalyst, the synthesis route is short, the energy consumption is low, the environmental protection is facilitated, and the large-scale chiral preparation of the isopentenyl indole alkaloid Debromofloutramine B is facilitated; the method also has the characteristics of relatively good atom economy and high product yield.

The method for manufacturing an intermediate compound for shikonin synthesis of the present invention comprises the steps of: reacting 1,5-dihydroxynaphthalene with dimethyl sulfate to prepare 1,5-dimethoxynaphthalene; reacting 1,5-dimethoxynaphthalene with N-bromosuccinimide (NBS) to prepare 1,5-dibromo -4,8-dimethoxynaphthalene; introducing a methoxy group into 1,5-dibromo-4,8-dimethoxynaphthalene using copper iodide (CuI) and 1,10-phenanthroline as a catalyst to prepare 1,4,5,8-tetramethoxynaphthalene; performing formylation of 1,4,5,8-tetramethoxynaphthalene using phosphoryl chloride (POCl3) to prepare 2-formyl-1,4,5,8-tetramethoxynaphthalene; and forming a boron complex using pinacolborane (HBpin) and 3,3-dimethylallyl bromide and reacting the boron complex with 2-formyl -1,4,5,8-tetramethoxynaphthalene to prepare a prenylated shikonin intermediate. Compared to conventional synthetic methods, the method of the present invention offers milder reaction conditions, shorter reaction time, and improved yield, thereby greatly enhancing the economic feasibility of shikonin synthesis.

The invention belongs to the field of high polymer materials, and relates to a clean construction method of a halogen-free phosphorus-free flame-retardant epoxy polymerization system. The preparation method comprises the following steps: preparing an intermediate I from 2, 2 '-diallyl bisphenol and allyl bromide under the action of potassium carbonate; carrying out rearrangement reaction on the intermediate I to prepare an intermediate II; and carrying out etherification and ring-closure reaction on the intermediate II and epoxy chloropropane under the action of a catalyst and sodium hydroxide to obtain the epoxy resin monomer III. The halogen-free phosphorus-free flame-retardant epoxy resin polymer is obtained by mixing an epoxy resin monomer with a curing agent, melting, performing injection molding and curing. The halogen-free and phosphorus-free flame retardant polymer obtained by the invention can reach the flame retardant grade of UL94-V0 grade.

This invention provides a ( E This invention relates to the field of pharmaceutical synthesis technology and provides a method for synthesizing 3,5-dihydroxy-4-isopropylstilbene. The method comprises three steps: starting with 3,5-dimethoxy-bromobenzene as a starting material, isopropylation is carried out under acidic conditions to obtain 3,5-dimethoxy-4-isopropylstilbene; further, a Heck reaction is performed with styrene under palladium catalysis to obtain (…). E )-3,5-dimethoxy-4-isopropylstilbene; demethylation reaction yields the ( E 3,5-Dihydroxy-4-isopropylstilbene. Compared to existing synthetic routes, the synthetic method of this invention significantly shortens the synthetic path, has higher atom utilization, higher product yield, and is environmentally friendly.

The invention relates to a method for preparing a bathroom mat from a nano antibacterial and mildew-proof environment-friendly material, and belongs to the technical field of bathroom mats. Polyvinyl chloride, an antioxidant, a stabilizer, trioctyl trimellitate, a filler, polyester, a lubricant, a plasticizer and a mildew-proof antibacterial agent are put into a mixing machine to be stirred, extruded in a double-screw extruder, mixed on a double-roller open mill and tableted on a flat vulcanizing machine, and the nano antibacterial mildew-proof environment-friendly material bathroom mat is obtained. The mildew-proof antibacterial agent is prepared by the following steps: stirring 3-mercaptoquinoline, methyl pyrrolidone, O-allyl-2-bromophenol ether and triethanolamine to react; adding tributyl isopropenyl tin, stirring to react, and distilling to remove the methyl pyrrolidone, thereby obtaining the product. The prepared bathroom mat has excellent mildew resistance and good bacteria resistance, has lasting mildew-proof and antibacterial effects, and is an ideal bathroom mat manufacturing material.

The invention provides a preparation process of n-propyl cyclopentadienyl tri (dimethylamino) zirconium. The preparation process comprises the following two steps: step 1, preparing n-propyl cyclopentadiene; the method comprises the following steps: taking a mixture of brominated cyclopentadiene and propyl magnesium bromide as a raw material to react, filtering out solid impurities after the reaction is finished, and carrying out reduced pressure distillation to obtain an n-propyl cyclopentadiene product; step 2, preparation of n-propyl cyclopentadiene tri (dimethylamino) zirconium; according to the method, n-propyl cyclopentadiene and a tetra (dimethylamino) zirconium solution are used as raw materials for reaction, and after the reaction is finished, reduced pressure distillation is performed to obtain n-propyl cyclopentadiene tri (dimethylamino) zirconium. The invention also relates to a film-forming preparation method of the precursor composition, and the precursor composition forms an oxide film, a nitride film or a nitrogen oxide film. According to the invention, the deposition quality defect of the pure propyl cyclopentadienyl tri (dimethylamino) zirconium precursor raw material due to high viscosity is overcome.

The invention discloses a modified molecular sieve capable of adsorbing and regenerating high-boiling-point substances and a preparation method thereof. According to the molecular sieve, a tetrapropylammonium bromide and N-bromoacetamide double-template system is adopted, a high-silicon ZSM-5 molecular sieve with the silica-alumina ratio larger than 300 is prepared through a guided gel-assisted hydrothermal synthesis method, and Ni metal is loaded for modification. The product has excellent hydrophobicity (the water contact angle is greater than 120 degrees) and a mesoporous structure, and can efficiently adsorb macromolecular organic matters such as coal tar and the like. Ni2 + / NiO bifunctional sites are innovatively introduced, adsorption selectivity is enhanced through pi-complexation, low-temperature desorption assisted by ethanol at the temperature of 80-120 DEG C is realized, and the desorption rate is increased by 3-5 times. Compared with a traditional method, the technology has the advantages of cheap raw materials, high crystallinity (greater than 95%), carbon deposition resistance, cyclic regeneration and the like, and is suitable for resourceful treatment of high-boiling-point organic matters in industrial waste gas.

An electrolyte (102) of a zinc-bromine static battery (104), comprising zinc bromide in molar concentration from 1.5 to 3.0 M; a mixture of two or more quaternary ammonium salts in 30 to 55 % of the molar concentration of the ZnBr2; a glycol based anti-freezing agent in molar concentration 0.1 to 2.0 M; and one or more additional supporting ionic conducting agents selected from zinc chloride, potassium chloride, magnesium chloride, lithium chloride and calcium chloride, where each or the combination are present in a molar concentration 0.5 to 2 M. The ammonium salts may be selected from tetrapropylammonium bromide (TPAB) or chloride or tetrabutylammonium bromide (TBAB) or chloride along with tetraethylammonium bromide (TEAB) or chloride. The anti-freezing agent may be selected from monoethylene glycol, propylene glycol, 1,3-butylene glycol, polyethylene glycol 200, polyethylene glycol 400, or a combination thereof. The electrolyte may be free of pH maintaining agents and buffering agents.

The invention provides a preparation method of octabromoS ether, and belongs to the technical field of flame-retardant materials. According to the preparation method, bisphenol S and allyl bromide are subjected to a carbon-oxygen coupling reaction under catalysis of a transition metal compound catalyst, bisphenol S diallyl ether and hydrogen bromide are obtained, hydrogen bromide can be recycled in a subsequent addition reaction, and the cost is saved; then hydrobromic acid and bisphenol S diallyl ether are subjected to an addition-electrophilic substitution reaction under catalytic oxidation of hydrogen peroxide to obtain octabromo-S ether, and high-toxicity bromine is not adopted; hydrogen peroxide is reduced into water in the reaction, so that the method is green and environment-friendly.

This invention provides a ZSM-48 and ZSM-5 composite molecular sieve, its preparation method, and its application. The method includes: mixing a template agent, a silicon source, an aluminum source, water, and an alkali source in a molar ratio of (0.01-0.5):1:(0.005-0.05):(10-100):(0.03-0.2) to obtain an initial gel; the template agent is tetrapropylammonium bromide and / or hexamethyldiammonium bromide; adding seed crystals to the initial gel and crystallizing to obtain a crystallized product; the seed crystals are ZSM-5 molecular sieve and / or ZSM-48 molecular sieve, with a mass ratio of seed crystal to silicon source of (0.01-0.2):1; calcining and ammonium exchange of the crystallized product to obtain the ZSM-48 and ZSM-5 composite molecular sieve. This invention significantly improves product purity and inhibits the formation of impurity crystals while ensuring the relative crystallinity of the composite molecular sieve by introducing heterogeneous seed crystals and a two-step crystallization process.

The invention provides a preparation method of spirolactone, and relates to the technical field of organic synthesis. The preparation method of spirolactone provided by the invention comprises the following steps: taking 4-androstene-3, 17-diketone as a raw material, carrying out nucleophilic addition reaction on the 4-androstene-3, 17-diketone and an organic zinc reagent 3-tert-butoxy-3-oxypropyl zinc bromide, then carrying out elimination-lactonization under the catalysis of trifluoroacetic acid, and completing lactonization while removing tert-butyl; then sequentially carrying out etherification reaction and oxidative dehydrogenation reaction to obtain canrenone, and finally carrying out addition reaction on canrenone and thioacetic acid to obtain spirolactone. The preparation method provided by the invention provides a novel construction method of 21-carboxylic acid-gamma-lactone, the method is good in specificity, the total mass yield of spirolactone is greater than 92%, and the total mass yield is high; moreover, the HPLC purity of the spirolactone prepared by the preparation method provided by the invention is greater than 99.7%, which is far higher than the purity of the spirolactone prepared by the existing process.

The present invention relates to a preparation method of montelukast sodium intermediate, belonging to the field of pharmaceutical chemistry. In the present invention, crotonic acid is used as the starting material, and ethyl 3-butenoate is generated through esterification rearrangement reaction. The double bond of ethyl 3-butenoate undergoes epoxidation reaction with m-chloroperoxybenzoic acid to obtain an epoxy compound. The epoxy compound reacts with thiourea to obtain a cyclic sulfur compound. The cyclic sulfur compound undergoes ring opening with a cuprous salt reagent and cyclopropylmagnesium bromide, and finally, it is further hydrolyzed under alkaline conditions to obtain 1-mercaptomethylcyclopropylacetic acid. This method has cheap and easily available starting materials, reducing the material cost; in the reaction process, the use of highly toxic cyanide reagents or extremely explosive diazomethane is avoided, improving the production safety, and the technological process is simple and easy to implement; the number of reaction steps is reduced, the production cost can be greatly reduced, which is beneficial to industrial production.

The invention provides an ammonium / phosphorus-based electrolyte, and belongs to the technical field of aqueous zinc ion batteries, the electrolyte comprises a zinc salt, water, an organic solvent and an organic salt additive, the zinc salt comprises zinc sulfate, the organic solvent comprises ethylene glycol and / or N, N-dimethylformamide, and the organic salt additive comprises sodium hydroxide and sodium hydroxide. The organic salt additive is prepared from at least one of 3-bromopropyl trimethyl ammonium bromide, tetrapropyl ammonium bromide and methyl triphenyl phosphorus bromide; in the electrolyte, the concentration of the zinc salt is 1-3 mol / L, and the concentration of the organic salt additive is 0.1-0.3 mol / L. The electrolyte can successfully excite and stabilize high-reversible four-electron redox reaction of the zinc-iodine battery from I <-> to I < + >, so that the specific capacity, the electrode potential, the energy density and the cycle performance of the zinc-iodine battery are remarkably improved. The invention also provides a preparation method of the ammonium / phosphorus-based electrolyte and application of the ammonium / phosphorus-based electrolyte in preparation of an aqueous zinc-iodine battery.

The invention belongs to the technical field of fine chemicals, medicines and materials, and particularly relates to a preparation method of an aryl triepoxypropane compound. The preparation method comprises the following steps: 1) mixing 2, 6-diallylphenol with a first solvent, adding allyl bromide and alkali to obtain a mixture, heating and refluxing the mixture, reacting, and cooling to room temperature to obtain 1, 3-diallyl-2-allyloxybenzene as shown in a formula I; and 2) reacting the 1, 3-diallyl-2-allyloxybenzene as shown in the formula I, a metal complex catalyst and an oxidizing agent in a second solvent to obtain the aryl triepoxypropane compound as shown in a formula II. The preparation method has the advantages of cheap and easily available raw materials, simple and mild reaction, low catalyst price and high reaction yield, and can realize industrial production.

The application discloses a recycling process of propiconazole 4-H isomer, and aims at solving the problems of low yield and serious pollution caused by the waste of 4-H isomer in traditional processes. The closed loop cycle process is constructed. After condensation reaction, the process is subjected to sectional pressure change and four-stage gradient temperature rectification, so that toluene, unreacted raw materials, propiconazole products, and mixtures of propiconazole and 4-H isomer and rectification kettle residues are separated in sequence and enriched. The kettle residue polymers are selectively hydrolyzed by using acetic acid-sodium acetate buffer solution, the effective components physically wrapped are released and recovered. After the above isomer mixtures and the recovered organic phase are combined and purified, the isomer mixtures are efficiently converted into starting raw material propyl bromo-ketone under the catalysis of Lewis acid and by using trimethyl bromosilane. Finally, high-purity propyl bromo-ketone is recovered by rectification and is reused in the condensation section. The yield loss of chiral by-products is completely eliminated, the atom economy maximization and solid waste near zero emission are realized, and the economic and environmental benefits are remarkable.

The invention belongs to the technical field of fracture acidizing in the field of petroleum engineering, and relates to a preparation method of a chelating alkaline prepad fluid for fracture acidizing, which comprises the following steps: firstly preparing tetrapropylamine-N, N, N ', N'-tetraacetic acid, and uniformly mixing potassium hydroxide and methanol to obtain a mixed solution I; uniformly mixing tetrapropylammonium bromide and methanol to obtain a mixed solution II; quickly adding the mixed solution I into the mixed solution II, and continuously stirring until all precipitates are separated out; filtering and precipitating under reduced pressure to obtain a faint yellow liquid which is a crude product; refining the crude product, cooling and crystallizing to obtain a tetrapropylamine-N, N, N ', N'-tetraacetic acid finished product; the preparation method comprises the following steps: preparing tetrapropylamine-N, N, N ', N'-tetraacetic acid and EDTA (Ethylene Diamine Tetraacetic Acid) disodium into an aqueous solution, namely prepad fluid; barium and strontium scales and stratum pollution and clay components can be effectively dissolved; while the fracturing acidizing effect is guaranteed, the environmental protection property and the equipment durability are greatly improved, and the fracturing acidizing agent has wide application prospects and market value.

The invention provides a Silicalite-1 molecular sieve as well as a preparation method and application thereof. The Silicalite-1 molecular sieve is prepared from raw materials including tetrapropylammonium bromide and a silicon source water solution, and optionally, the Silicalite-1 molecular sieve also comprises an alkaline reagent; wherein the molar ratio of SiO2 to tetrapropylammonium bromide to OH <-> to H2O is 1: (0.06-5): (0-1): (1-200). The preparation method comprises the following steps: grinding tetrapropylammonium bromide into powder, optionally grinding the tetrapropylammonium bromide and an alkaline reagent into powder, then adding a silicon source aqueous solution, continuously grinding to uniformly mix all the raw materials, fully reacting, crystallizing, drying a solid product obtained after separation, and roasting to obtain the Silicalite-1 molecular sieve. When the Silicalite-1 molecular sieve is prepared, water does not need to be additionally added, the operation is simple, the preparation period is short, and less wastewater is generated.

The application relates to the technical field of high polymer materials, and discloses a single-end type dihydroxyalkylamine modified polysiloxane as well as a preparation method and application thereof, and the structure is shown in formula I, wherein the value range of n is a natural number of 10-65. The preparation process is as follows: diethanolamine, hexamethyldisilazane, allyl bromide and alpha-(trimethylsilyl)-omega-dimethylsilyl polydimethylsiloxane shown in formula M1 are used as raw materials, and a single-end trimethylsilyl group and a dihydroxyalkylamine group are substituted at the other end under the catalysis of a Karstedt catalyst, the dihydroxyalkylamine modified polysiloxane has excellent stability and hydrophilicity, and the emulsion prepared by using the dihydroxyalkylamine modified polysiloxane has high hydrophilicity and good yellowing resistance when treating fabric.

The invention belongs to the technical field of chemical synthesis, and particularly relates to a preparation method of 2-(4-(cyclopropyl formyl) phenyl)-2-methyl tert-butyl propionate 13C. Comprising the following steps: introducing carbon dioxide (13C) into tetrahydrofuran and a reagent A at-80 DEG C to synthesize cyclopropanecarboxylic acid (13C), wherein the reagent A is cyclopropyl magnesium bromide and cyclopropyl magnesium iodide: adding the cyclopropanecarboxylic acid (13C), dichloromethane, dimethyl hydroxylamine hydrochloride and 4-dimethylaminopyridine into triethylamine at room temperature, and reacting at the temperature of-80 DEG C to obtain the cyclopropanecarboxylic acid (13C). The preparation method comprises the following steps: synthesizing N-methoxy-N-methyl cyclopropanecarboxamide-13C from 1-ethyl-(3-dimethylaminopropyl) carbodiimide hydrochloride; the preparation method comprises the following steps: adding 2-(4-bromophenyl)-2-tert-butyl methyl propionate and tetrahydrofuran into a reaction kettle, dropwise adding an alkali solution at the temperature of-40 DEG C, and dropwise adding N-methoxy-N-methylcyclopropanecarboxamide-13C to synthesize 2-(4-(cyclopropanecarboxyl) phenyl)-2-tert-butyl methyl propionate-13C, thereby obtaining the 2-(4-(cyclopropanecarboxyl) phenyl)-2-tert-butyl methyl propionate-13C. The method is reasonable in route, low in cost, high in yield and easy to industrialize.

The present invention relates to a cyanoacetate method for preparing valproic acid via a 2-propyl-2-cyanovalerate intermediate shown in formula I: cyanoacetate and 1-chloropropane are reacted in a K 2 CO 3 Under the action of the composite catalytic dipropylation, 2-propyl-2-cyanovalerate shown in Ⅰ is obtained, and the latter is hydrolyzed and decarboxylated to obtain valproic acid, and the preparation reaction is as follows: #imgabs0#R is selected from methyl, ethyl, propyl, isopropyl, butyl, tert-butyl or pentyl; the catalyst for dipropylation is composed of catalyst A and catalyst B; catalyst A is selected from tetrabutylammonium chloride, tetrabutylammonium bromide, tetrabutylammonium iodide, tetrapropylammonium chloride, tetrapropylammonium bromide, tetrapropylammonium iodide, tetraethylammonium chloride, tetraethylammonium bromide, tetraethylammonium iodide, tetramethylammonium chloride, tetramethylammonium bromide or tetramethylammonium iodide; catalyst B is selected from KBr or KI; the dipropylation reaction temperature is selected from 60°C to 120°C; the reaction time is selected from 1.0h to 12h. Impurities in the obtained valproic acid or sodium valproate: total impurities are less than 0.2%, single impurities are less than 0.05%; the valproic acid content is greater than 99.90%. The cyanoacetate method for preparing valproic acid or sodium valproate meets the quality requirements.

The invention belongs to the technical field of molecular sieve synthesis, and discloses a preparation method of a flaky hollow TS-1 molecular sieve for phenol hydroxylation, the molecular sieve and application, and the preparation method comprises the following synthesis steps: dropwise adding tetraethyl orthosilicate into an aqueous solution containing tetrapropylammonium hydroxide; after clarification, dropwise adding a solution containing tetrabutyl titanate and isopropanol into the solution; after high-temperature alcohol removal, N, N-dimethylformamide is added; carrying out hydrothermal crystallization, centrifugation, drying and calcination; adding the collected maternal zeolite into an aqueous solution of tetrapropylammonium bromide and ethanolamine; and carrying out hydrothermal crystallization, centrifugation, drying and calcination. The method is low in cost and simple to operate, the sheet-shaped hollow titanium silicalite molecular sieve is synthesized, the diffusion mass transfer rate is increased, and the sheet-shaped hollow titanium silicalite molecular sieve has a large number of hexa-coordination active titanium species and has good catalytic activity in 1-hexene epoxidation, cyclohexene epoxidation, propylene epoxidation and phenol hydroxylation reactions.

The application discloses a method for hydrogen sulfide resource utilization by using surfactant-induced modified zeolite to catalyze butene and hydrogen sulfide to synthesize butyl mercaptan. The surfactant-induced modified zeolite is prepared by the following steps: dissolving 0.3-0.4g of cetyl tripropyl ammonium bromide in 0.06-0.1mol / L of NaOH aqueous solution, then adding 1-1.2g of FAU type zeolite, stirring for 1-2h at room temperature, transferring the mixture into a high-pressure reaction kettle, heating for 30-90h at 150-170 DEG C, performing solid-liquid separation, calcining the solid at 500-700 DEG C for 3-5h, and then using an equal-volume impregnation method to place the calcined solid in a molybdate solution, standing, and drying to obtain the surfactant-induced modified zeolite. The catalyst has the advantages of good stability, good sulfur resistance and high selectivity, and the service life of the catalyst is greatly improved.

The invention relates to the technical field of acidification and yield increase of petroleum and natural gas, and discloses a drag-reducing retarded acid solution composition, a drag-reducing retarded acid solution, and a preparation method and application of the drag-reducing retarded acid solution. The composition comprises the following components: a retarder which is compounded by at least two of C2-C8 binary acids; the corrosion inhibitor is at least one of pyridine quaternary ammonium salt, quinoline quaternary ammonium salt, naphthenic acid imidazoline and lauric acid imidazoline; the corrosion inhibition synergist is at least one of antimony trioxide, glutaraldehyde and potassium iodide; the drag reducer is prepared from at least one of acryloyloxyethyl trimethyl ammonium chloride, 2-methacryloyloxyethyl trimethyl ammonium chloride, dimethyl diallyl ammonium chloride and N-vinyl-2-pyrrolidone, and N, N-dimethyl dodecyl allyl ammonium bromide, N, N-dimethyl hexadecyl allyl ammonium bromide and N, N-dimethyl hexadecyl allyl ammonium bromide, and at least one of N, N-dimethyl hexadecyl allyl ammonium bromide and N, N-dimethyl hexadecyl allyl ammonium bromide. And polymerizing at least one of N, N-dimethyl octadecyl allyl ammonium bromide. The drag-reducing and retarding acid liquor can reduce the corrosion rate and corrosion to a tubular column under the condition of ultrahigh temperature.

The invention discloses a high-weather-resistance photovoltaic panel coating material and a preparation method thereof, and relates to the field of coating materials. When the high-weather-resistance photovoltaic panel coating material is prepared, 4, 4 '-dibromo benzophenone and N-methylallylamine react to prepare a functional monomer; the preparation method comprises the following steps: carrying out a reaction on dimethyl diethoxy silane, allyl dimethyl methoxy silane and (N, N-dimethyl-3-aminopropyl) trimethoxy silane, and then carrying out a reaction on the obtained product and 3-trifluoromethyl phenylpropyl bromide so as to prepare modified polysiloxane; the preparation method comprises the following steps: reacting microcrystalline cellulose with maleic anhydride, 2-amino-3-cyano-4, 5-dimethyl pyrrole, N, N-diethyl hydroxylamine and 1-(4-hydroxybenzene) ethanol in sequence, so as to prepare functional cellulose; the functional cellulose, the modified polysiloxane, the functional monomer, sodium tert-butoxide, zinc acetate and tetrahydrofuran are mixed, and the high-weather-resistance photovoltaic panel coating material is prepared. The high-weather-resistance photovoltaic panel coating material prepared by the invention has antifouling, waterproof, dustproof and self-repairing capabilities.

The invention relates to the technical field of agricultural disease control, in particular to application of indole compounds and pharmaceutically acceptable salts, solvates, crystal forms, prodrugs, stereoisomers and tautomers thereof in preparation of drugs for inhibiting pathogenic fungi pathogenic key protein kinase CgSlt2. The invention provides a novel CgSlt2 targeting inhibitor for the first time, in particular, indole compounds ((S)-N-(1-(1H-indol-3-yl)-4-(methylamino)-4-oxobutyl-2-yl)-8-bromine-1, 6-naphthyridine-2-formamide) and ((S)-N-(2-((1H-indol-3-yl)-1-(methylamino)-1-oxopropyl)-8-bromine-1, 6-naphthyridine-2-formamide) are subjected to a one-pot reaction to prepare the CgSlt2 targeting inhibitor. The CgSlt2 inhibitor (2, 6-naphthyridine-2-formamide) has the characteristics of strong target property and high activity, and shows excellent pathogenicity for inhibiting colletotrichum gloeosporioides complex strains.