370results about "Ether preparation by ester reactions" patented technology

The utility model discloses equipment for producing high-purity methyl ethyl ether, which relates to the field of synthesis of chemical compounds and comprises a reaction device, a heating component, a cold bath tank, a crude product receiving tank, a heavy component removal tower, a light component removal tower, a first reboiler, a second reboiler, a first condenser, a second condenser, a recovery tank, a product receiving tank and a controller, raw materials including sodium methoxide and halogenated ethane directly react under the anhydrous condition, a catalyst is not needed, crude methyl ethyl ether is produced, then the crude methyl ethyl ether enters a heavy component removal tower, crude methyl ethyl ether gas with heavy components removed enters a light component removal tower from the top of the light component removal tower after being detected to be qualified through a first online analysis and detection component, light component removal rectification is conducted, and methyl ethyl ether is obtained. Gas-phase impurities at the top of the light component removal tower are analyzed through the second online analysis and detection part, when the gas-phase impurities are detected to be qualified, the methyl ethyl ether product enters the product receiving tank, and then the high-purity methyl ethyl ether product is produced through continuous rectification, so that the product purity is high, the reaction temperature is low, the energy consumption is reduced, the reaction yield is high, and the production cost is low.

The invention belongs to the technical field of organic synthesis of ethers, and particularly relates to a method for continuously synthesizing ethylene glycol dimethyl ether. The method comprises the following steps that ethylene glycol, sodium hydroxide and methane chloride serve as raw materials, multi-stage continuous reaction is carried out in liquid membrane reactors to synthesize ethylene glycol dimethyl ether, ethylene glycol, sodium hydroxide and methane chloride are introduced into the first-stage liquid membrane reactor, sodium hydroxide and methane chloride are introduced into the subsequent stages of liquid membrane reactors, and the first-stage liquid membrane reactor and the second-stage liquid membrane reactor are connected with the second-stage liquid membrane reactor. A byproduct sodium chloride is separated from a reaction product in the previous-stage liquid membrane reactor and then enters the next-stage liquid membrane reactor, a byproduct sodium chloride is separated from a reaction product in the last-stage liquid membrane reactor and then clear liquid is obtained, and ethylene glycol dimethyl ether is obtained through rectification treatment. The invention develops a novel process mode for continuously synthesizing an ethylene glycol dimethyl ether product, and provides a new idea for large-scale continuous production of ethylene glycol dimethyl ether.

The invention belongs to the technical field of synthesis of ether organic compounds, and particularly relates to a one-pot catalyst-free method for preparing ethylene glycol dimethyl ether from ethylene glycol, which comprises the following steps: (1) adding ethylene glycol into a reaction kettle, heating to 120-140 DEG C, introducing methane chloride, and controlling the introduction amount of methane chloride to be 20-50% of the total molar amount of ethylene glycol; (2) adding NaOH into the reaction kettle in batches, and stirring for reaction at the reaction temperature of 120-140 DEG C; (3) after the last batch of NaOH is added, sampling and detecting every 20-25 minutes, and measuring the concentration lt of NaOH in the reaction liquid; and when the concentration is 0.05 mol / L, finishing the reaction, filtering, and carrying out post-treatment rectification on the filtrate to obtain the ethylene glycol dimethyl ether. The preparation raw material ethylene glycol can be derived from biomass or coal, dependence on petroleum resources is reduced, and meanwhile the preparation method has the advantages of being few in side reaction and low in production cost.

The invention discloses a titanium-doped lamellar FER molecular sieve and application thereof in a rutin electrochemical sensing detector, and belongs to the technical field of molecular sieve synthesis and electrochemical sensor detection. The titanium-doped lamellar FER molecular sieve is prepared by taking an organic compound as a template agent through a hydrothermal method. The structural formula of the organic compound is NH2-C2H4-NH-(CH2) n-O-(p-C6H4) 2-O-(CH2) n-NH-C2H4-NH2, and the structural formula of the organic compound is NH2-C2H4-NH-CH2. Wherein n ranges from 10 to 16. The preparation method comprises the following steps: immobilizing chitosan on a titanium-doped lamellar FER molecular sieve to obtain a composite material, and modifying an electrode by adopting the obtained composite material to construct an electrochemical sensor; the obtained electrochemical sensor is used for detecting and analyzing rutin. The rutin detection concentration linear range of the obtained electrochemical sensor reaches 0.1-10 [mu] mol / L, the concentration detection range is wide, the detection sensitivity, accuracy, repeatability and selectivity are high, the detection lower limit is low, and the stability is good.

The invention relates to a preparation method of high-purity o-phenylphenoxyethanol. The preparation method comprises the following steps: S1, reacting o-phenylphenol with ethylene carbonate in the presence of a catalyst to obtain an o-phenylphenoxyethanol crude product; s2, dissolving the o-phenyl phenoxyethanol crude product in an organic solvent; and S3, adding an anti-solvent, cooling and crystallizing to obtain the o-phenylphenoxyethanol. The o-phenylphenoxyethanol obtained by the method is high in purity, namely the HPLC (high performance liquid chromatography) purity is more than or equal to 99.5%, the single impurity is less than or equal to 0.1%, the o-phenylphenoxyethanol can be produced by conventional equipment, the process operation is simple, the production cost is low, an ethylene oxide method can be replaced, and the industrial production is easy.

The invention relates to a gemini surfactant for thickened oil recovery and a preparation method thereof, and belongs to the technical field of thickened oil recovery. The preparation method of the gemini surfactant for thickened oil recovery comprises the following steps: dissolving ethylene glycol dihydric alcohol and paratoluensulfonyl chloride in a tetrahydrofuran solvent, and carrying out substitution reaction under an alkaline condition to obtain an intermediate I; adding nonyl phenol and the intermediate I into a mixed solvent of tetrahydrofuran and N, N-dimethylformamide, and carrying out etherification reaction under an alkaline condition to obtain a gemini precursor II; and mixing an alkylphenol polyoxyethylene ether surfactant, the gemini precursor II and a formaldehyde aqueous solution, and carrying out a phenolic aldehyde condensation polymerization reaction under an acidic condition to obtain the gemini surfactant. The gemini surfactant prepared by the preparation method has good temperature resistance and salt tolerance, the preparation method is simple, the synthesis cost is low, and the gemini surfactant has good economical efficiency and is beneficial to realizing large-scale industrial production.

The invention discloses a preparation method of pentaerythritol triallyl ether, wherein the method comprises: providing reaction raw materials and a catalyst, heating to a preset temperature and keeping the temperature for a first preset time, controlling water separation in a first mode and dripping propylene chloride at a first preset speed for 5 hours to obtain a first-stage reaction product; adding alkali solution and a catalyst into the product of the previous reaction step three times and controlling water separation in a second water separation mode, a third water separation mode, and a fourth water separation mode, wherein the water separation in the first mode includes no water separation during all reaction time, the water separation in the second mode includes water separation during part of the reaction time, the water separation in the third mode includes water separation during all reaction time, and the water separation in the fourth mode includes water separation during all reaction time. By controlling different water separation modes, the selectivity of the triether can be effectively improved, the cost of pentaerythritol triallyl ether can be effectively reduced, and its application field is conducive to further expansion.

The invention relates to a preparation method of fluoro-ether, which comprises the following steps: providing a first reaction system which comprises paratoluensulfonyl chloride, fluorine-containing alcohol, an alkali metal hydroxide aqueous solution, a phase transfer catalyst and an organic solvent which is insoluble in water; performing a first reaction on the first reaction system to generate p-toluenesulfonate, then standing for layering, and taking an organic phase; providing a second reaction system, wherein the second reaction system comprises the organic phase, fluorine-containing alcohol and an alkali metal hydroxide aqueous solution; and carrying out a second reaction on the second reaction system to generate fluoroether. The preparation method is simple in operation steps, does not need or reduces the steps of extraction, separation and the like, and has the advantage of saving reagent cost.

The present invention provides a method for producing a bio-derived branched alkyl glyceryl ether, the method comprising: a step for producing a bio-derived branched primary alcohol having a branched alkyl group having 6 to 12 carbon atoms, the step including dimerizing at least one component selected from the group consisting of a bio-derived linear primary alcohol having a linear alkyl group having 3 to 6 carbon atoms, a bio-derived linear primary alcohol having a linear alkenyl group having 3 to 6 carbon atoms, a bio-derived linear aldehyde having a linear alkyl group having 3 to 6 carbon atoms, and a bio-derived linear aldehyde having a linear alkenyl group having 3 to 6 carbon atoms; and a step for producing a bio-derived branched alkyl glyceryl ether using the bio-derived branched primary alcohol. The present invention also provides a bio-derived branched alkyl glyceryl ether produced by the method.

The invention discloses a film-embedded conjugated oligomeric electrolyte based on a natural product, and the structure of the film-embedded conjugated oligomeric electrolyte takes a natural polyphenol compound as a conjugated skeleton part, so that the overall biocompatibility of molecules is improved, and the toxicity is reduced; alkyl chains with different lengths or numbers are used as side chain parts to adjust the compatibility with a cell membrane and promote the membrane embedding and retention of molecules, and the alkyl chains can disturb the phospholipid arrangement of the cell membrane and increase the membrane permeability after the molecules are embedded into the membrane; a positively charged group is used as an end group part, and a negatively charged cell membrane is anchored through electrostatic attraction, so that the local molecular concentration is improved. The cell membrane is modified by the embedded membrane conjugated oligomeric electrolyte derived from the natural product, so that the permeability of the cell membrane is improved, the cytotoxicity is reduced, and the catalytic efficiency of cells is improved. The cell membrane is modified by the embedded membrane conjugated oligomeric electrolyte derived from the natural product, so that the permeability of the cell membrane is improved, the cytotoxicity is reduced, and the catalytic efficiency of cells is improved.

The application belongs to the technical field of electrolyte solvent synthesis and application, and discloses a fluorosulfone ether compound, a preparation method thereof and a sodium ion battery electrolyte. The structural general formula of the fluorosulfone ether compound is R'-O-L-SO2-R; wherein R' and R are respectively selected from C1-C6 alkyl; and L is a fluorinated alkylene group with a carbon atom number greater than or equal to 2. The fluorosulfone ether compound of the application can be applied to the sodium ion battery electrolyte, so that the high-voltage stability, low-temperature stability and interface stability of the electrolyte can be significantly improved.

The invention discloses a method for preparing anisole by taking dimethyl carbonate as a methylation reagent, a ternary concerted catalytic system is created for the first time to break through temperature limitation, phenol is efficiently activated by [BMIM] OH to generate high-activity phenoxy anions through a composite catalytic design of an alkaline ionic liquid / quaternary ammonium salt / nano metal oxide, the quaternary ammonium salt executes phase transfer and reaction path switching, and the anisole is prepared by taking dimethyl carbonate as a methylation reagent. The nano metal oxide has the effects of balance regulation and structural protection, and the conversion rate of phenol is gt according to the mass ratio of phenol to dimethyl carbonate to basic ionic liquid to quaternary ammonium salt compound to nano metal oxide being 94: (99-117): (2.82-7.52): (0.94-4.7): (0.47-3.76); the selectivity of anisole is gt; the method has the advantages that the concentration is 99%, decomposition of DMC and generation of by-products such as o-cresol are inhibited from the source, a self-settling separation-circulation method subverts a catalyst recovery mode, the by-products are directionally inhibited, the separation process is simplified, and the product can reach gt through single washing and reduced pressure distillation; and high-energy-consumption multi-tower rectification for substances with approximate boiling points in the traditional method is omitted, so that the economic benefit is greatly improved.

The present invention belongs to the technical field of organic synthesis, and particularly relates to a p-chlorophenyl ether compound, a preparation method thereof, and an application thereof. Disclosed by the present invention is a novel p-chlorophenyl ether compound, 3,3'-oxybis(1-(4-chlorophenoxy)isopropyl-2-ol). Mainly using p-chlorophenol and 3-chloro-1,2-propanediol as raw materials, in a mixed solvent of isopropanol and water, a reaction occurs in the presence of a base, and the reaction solution is subjected to column chromatography to obtain 3,3'-oxybis(1-(4-chlorophenoxy)isopropyl-2-ol). The preparation process of this compound is simple, the synthesis route is short, and the antibacterial ability is strong.

The invention discloses a preparation method of p-phenylethylether, p-phenylethylether is prepared from hydroquinone and diethyl carbonate in a high-selectivity manner under the catalysis of a catalyst, and the catalyst is a Zr / Ho-loaded SAPO molecular sieve catalyst. The process is green and environment-friendly, few in three wastes, high in catalyst reaction activity, good in stability, simple to separate and high in product yield, and has a good industrial application prospect.

The invention discloses a method for preparing ditrimethylolpropane, which comprises the following steps: a) trimethylolpropane and a brominating reagent are subjected to nucleophilic substitution reaction under the action of a catalyst I to obtain 2-bromo-2-ethyl-1, 3-propylene glycol; b) generating 2, 2-dimethylolbutanol sodium from trimethylolpropane under the action of a catalyst II; and c) carrying out a reaction on the 2, 2-dimethylol sodium butoxide and 2-bromo-2-ethyl-1, 3-propylene glycol under the action of a catalyst III to obtain the ditrimethylolpropane. The method has the advantages of high yield, few byproducts and high purity.

A use of a compound of formula Y: (Y) to form a protected nucleophile, wherein a single substituent selected from R1-R4 is -CH2-LG or -CH2-OH, wherein LG is a leaving group; at least one substituent s

The application discloses a titanium-doped sheet-layer FER molecular sieve and application of the titanium-doped sheet-layer FER molecular sieve in an electrochemical sensing detector for rutin, and belongs to the technical field of molecular sieve synthesis and electrochemical sensor detection. n -O-(p-C6H4)2-O-(CH2) n -NH-C2H4-NH2; wherein n is 10-16. The titanium-doped sheet-layer FER molecular sieve is immobilized with chitosan to obtain a composite material, an electrode is modified by using the obtained composite material to construct an electrochemical sensor, and the obtained electrochemical sensor is used for detecting and analyzing rutin. The concentration linear range of the electrochemical sensor for detecting rutin reaches 0.1-10 micromoles per liter, the concentration detection range is wide, the detection sensitivity, accuracy, repeatability and selectivity are high, the detection lower limit is low, and the stability is good.

The present invention relates to a crosslinking agent, a photosensitive resin composition and its use, wherein the crosslinking agent has a structure shown in formula (I) or formula (II), the crosslinking agent contains at least 3 benzyl ether groups or benzyl alcohol groups substituted on an aromatic group, and at least 2 oxyethylene groups, the photosensitive resin composition comprises the crosslinking agent, and also comprises a solvent, a photoacid generator and a hydroxyl-containing polyimide resin, and the use of the photosensitive resin composition, wherein the photosensitive resin composition is used for an OLED display panel. The photosensitive resin composition comprising the crosslinking agent provided by the present invention has good resolution and development film retention rate, and also has high anti-stripping performance, mechanical strength, and low small molecule volatility.

Provided herein are halogenated ether compounds of Formula (I), Formula (II), or Formula (III): Formula (I)Formula (II)Formula (III) Also provided are electrolytes comprising one or more compounds of Formula (I), Formula (II), or Formula (III) and electrochemical cells comprising electrolytes comprising one or more compounds of Formula (I), Formula (II), or Formula (III).

This invention provides novel fluorine-containing diether compounds. [Solution] Formula (1) below: JPEG2026065628000011.jpg30128 (In formula (1), R1 represents a fluorine atom or a perfluoroalkyl group having 1 to 10 carbon atoms, R2 may be the same or different, consisting of a methyl group, an ethyl group, -CH2CF3, or -CH2(C2F4). n Showing H n represents an integer between 1 and 10 (inclusive). A fluorine-containing diether compound represented by the following:

The application provides a kind of plane chiral boronic acid compound based on cycloaralkane skeleton and its synthesis method and application, the plane chiral compound has the structure shown in formula I;R 1 It is selected from one of C1-C8 alkyl, C1-C8 alkoxy, C1-C20 aryloxy.R 2 It is selected from one of hydrogen, fluorine, methyl, ethyl, methoxy, ester group, nitro group, phenyl, benzyl, tert-butyl, isopropyl.The application can effectively synthesize plane chiral boronic acid catalyst based on cycloaralkane skeleton, and the plane chiral boronic acid catalyst based on cycloaralkane skeleton can realize diol desymmetrization reaction.

The invention relates to a process for preparing an alkoxylated product. The aim of the invention is to provide aromatic polyols for preparing polyurethane-based and polyisocyanurate-based polymers, which ensure good miscibility with the isocyanate component and other components, have a good storage stability and render the end product flameproof. For this purpose, the invention devises a process for preparing an alkoxylated product by reacting bisphenol F with propylene carbonate and / or propylene oxide as propoxylation agent and ethylene carbonate and / or ethylene oxide as ethoxylation agent, the propoxylation agent and the ethoxylation agent being used in a molar ration of 70:30 to 45:55.

The present invention provides a method for asymmetric synthesis of cyclobutane derivatives. Compound 2 and PhBpin are used as substrates, and are mixed with a catalyst, a ligand, an additive, an oxidant, a base, water, and a solvent for reaction to generate a target compound 1. The reaction formula is as follows: wherein R 1 The present invention forms a chiral complex by using a chiral α-amino spirocyclic ligand and a Pd(II) center, thereby achieving high yield and high enantioselectivity and providing a new approach to the asymmetric synthesis of cyclobutane derivatives.

The present invention relates to a preparation method of galaxolide, comprising: preparing herb alcohol into herb alcoholate; reacting the herb alcoholate with a compound having a structural formula as shown in formula (1) to generate an intermediate having a structural formula as shown in formula (2), wherein in formula (1), R is a halogen element; and subjecting the intermediate to a transesterification reaction with methyl propionate under the action of a transesterification catalyst to obtain galaxolide. In the preparation method of galaxolide of the present invention, the raw materials and reactants are widely sourced, low in price, low in production cost, and the yield of galaxolide is high.

The present invention relates to halogenated alkenylalkoxymethyl ether compounds of the following general formula (1): R 1 CH2OCH2OCH2CH2CH=CH(CH2) a X 1 (1), wherein R 1 represents a hydrogen atom, a n-alkyl group having 1 to 9 carbon atoms, or a phenyl group, X 1 represents a halogen atom, and a represents an integer of 3 to 14. The present invention also relates to a method for producing terminal conjugated alkadien-1-yl acetate compounds of the following general formula (5): CH2=CHCH=CH(CH2) a OAc (5), wherein a is defined as above, and Ac represents an acetyl group, and a method for producing terminal conjugated alkadien-1-ol compounds of the following general formula (6): CH2=CHCH=CH(CH2) a OH (6), wherein a is defined as above.

The present invention relates to the technical field of chemical synthesis, and provides a method for synthesizing 5-chloro-2-(2-chloroethoxy)benzenesulfonamide. The method comprises: performing an amination reaction on 5-chloro-2-(2-chloroethoxy)benzenesulfonyl chloride and aqueous ammonia to obtain 5-chloro-2-(2-chloroethoxy)benzenesulfonamide. The above technical solution solves the problems of incomplete amination, unstable product quality, and subsequent deactivation of a hydrogenation catalyst in the production process of 5-chloro-2-(2-chloroethoxy)benzenesulfonamide in the related art, while also solving the problems of low product yield and high production and processing costs.

The invention relates to the technical field of organic synthesis, and discloses a synthetic method of aromatic acyl chloride, which comprises the following steps: at normal temperature, adding carboxyl modified quaternized cardanol into a reaction kettle, then adding anhydrous aluminum trichloride and trichlorotoluene, slowly heating to 70-75 DEG C, heating to 105-110 DEG C after no bubble is generated in the reaction, reacting for 1-2 hours, and cooling to room temperature to obtain the aromatic acyl chloride. And after the reaction is finished, transferring the reaction liquid into a distillation flask, and distilling to obtain the aromatic acyl chloride. The aromatic acyl chloride provided by the invention solves the problem of high energy consumption or introduction of other organic solvents, and has a good antibacterial effect.

The invention provides a cholesteric luminescent liquid crystal material with a high asymmetric factor, a film and a preparation method, and belongs to the technical field of photoluminescent materials. The cholesteric luminescent liquid crystal material prepared by the invention is obtained by taking 9, 9-dioctylfluorene as a central group through Suzuki reaction and Williamson synthesis. According to the material, supermolecule co-assembly can be realized in a thermal annealing process under the action of a chiral binaphthalene inducer by regulating and controlling an alkyl chain and an effective conjugate length, so that a relatively high CPL signal is obtained. The chiral liquid crystal co-assembly thin film and the polymer network thin film have the advantages that the chiral liquid crystal co-assembly thin film and the polymer network thin film prepared by the aid of the method are ingenious in design and low in cost, and the chiral liquid crystal co-assembly thin film and the polymer network thin film can be applied to advanced photon applications such as 3D (three-dimensional) imaging and anti-counterfeiting encryption.