105results about "Ether preparation by ester reactions" patented technology

The application belongs to the technical field of electrolyte solvent synthesis and application, and discloses a fluorosulfone ether compound, a preparation method thereof and a sodium ion battery electrolyte. The structural general formula of the fluorosulfone ether compound is R'-O-L-SO2-R; wherein R' and R are respectively selected from C1-C6 alkyl; and L is a fluorinated alkylene group with a carbon atom number greater than or equal to 2. The fluorosulfone ether compound of the application can be applied to the sodium ion battery electrolyte, so that the high-voltage stability, low-temperature stability and interface stability of the electrolyte can be significantly improved.

The application discloses a titanium-doped sheet-layer FER molecular sieve and application of the titanium-doped sheet-layer FER molecular sieve in an electrochemical sensing detector for rutin, and belongs to the technical field of molecular sieve synthesis and electrochemical sensor detection. n -O-(p-C6H4)2-O-(CH2) n -NH-C2H4-NH2; wherein n is 10-16. The titanium-doped sheet-layer FER molecular sieve is immobilized with chitosan to obtain a composite material, an electrode is modified by using the obtained composite material to construct an electrochemical sensor, and the obtained electrochemical sensor is used for detecting and analyzing rutin. The concentration linear range of the electrochemical sensor for detecting rutin reaches 0.1-10 micromoles per liter, the concentration detection range is wide, the detection sensitivity, accuracy, repeatability and selectivity are high, the detection lower limit is low, and the stability is good.

Provided herein are halogenated ether compounds of Formula (I), Formula (II), or Formula (III): Formula (I)Formula (II)Formula (III) Also provided are electrolytes comprising one or more compounds of Formula (I), Formula (II), or Formula (III) and electrochemical cells comprising electrolytes comprising one or more compounds of Formula (I), Formula (II), or Formula (III).

This invention provides novel fluorine-containing diether compounds. [Solution] Formula (1) below: JPEG2026065628000011.jpg30128 (In formula (1), R1 represents a fluorine atom or a perfluoroalkyl group having 1 to 10 carbon atoms, R2 may be the same or different, consisting of a methyl group, an ethyl group, -CH2CF3, or -CH2(C2F4). n Showing H n represents an integer between 1 and 10 (inclusive). A fluorine-containing diether compound represented by the following:

The application provides a kind of plane chiral boronic acid compound based on cycloaralkane skeleton and its synthesis method and application, the plane chiral compound has the structure shown in formula I;R 1 It is selected from one of C1-C8 alkyl, C1-C8 alkoxy, C1-C20 aryloxy.R 2 It is selected from one of hydrogen, fluorine, methyl, ethyl, methoxy, ester group, nitro group, phenyl, benzyl, tert-butyl, isopropyl.The application can effectively synthesize plane chiral boronic acid catalyst based on cycloaralkane skeleton, and the plane chiral boronic acid catalyst based on cycloaralkane skeleton can realize diol desymmetrization reaction.

The invention relates to a process for preparing an alkoxylated product. The aim of the invention is to provide aromatic polyols for preparing polyurethane-based and polyisocyanurate-based polymers, which ensure good miscibility with the isocyanate component and other components, have a good storage stability and render the end product flameproof. For this purpose, the invention devises a process for preparing an alkoxylated product by reacting bisphenol F with propylene carbonate and / or propylene oxide as propoxylation agent and ethylene carbonate and / or ethylene oxide as ethoxylation agent, the propoxylation agent and the ethoxylation agent being used in a molar ration of 70:30 to 45:55.

The present invention relates to halogenated alkenylalkoxymethyl ether compounds of the following general formula (1): R 1 CH2OCH2OCH2CH2CH=CH(CH2) a X 1 (1), wherein R 1 represents a hydrogen atom, a n-alkyl group having 1 to 9 carbon atoms, or a phenyl group, X 1 represents a halogen atom, and a represents an integer of 3 to 14. The present invention also relates to a method for producing terminal conjugated alkadien-1-yl acetate compounds of the following general formula (5): CH2=CHCH=CH(CH2) a OAc (5), wherein a is defined as above, and Ac represents an acetyl group, and a method for producing terminal conjugated alkadien-1-ol compounds of the following general formula (6): CH2=CHCH=CH(CH2) a OH (6), wherein a is defined as above.

The invention provides a cholesteric luminescent liquid crystal material with a high asymmetric factor, a film and a preparation method, and belongs to the technical field of photoluminescent materials. The cholesteric luminescent liquid crystal material prepared by the invention is obtained by taking 9, 9-dioctylfluorene as a central group through Suzuki reaction and Williamson synthesis. According to the material, supermolecule co-assembly can be realized in a thermal annealing process under the action of a chiral binaphthalene inducer by regulating and controlling an alkyl chain and an effective conjugate length, so that a relatively high CPL signal is obtained. The chiral liquid crystal co-assembly thin film and the polymer network thin film have the advantages that the chiral liquid crystal co-assembly thin film and the polymer network thin film prepared by the aid of the method are ingenious in design and low in cost, and the chiral liquid crystal co-assembly thin film and the polymer network thin film can be applied to advanced photon applications such as 3D (three-dimensional) imaging and anti-counterfeiting encryption.

A solid catalyst component for the polymerization of olefins made from or containing a magnesium halide, a titanium compound having at least a Ti-halogen bond, and at least an electron donor compound selected from 1,3-diethers.

The application belongs to the field of medicine synthesis, and specifically provides a daunorubicin intermediate compound. The daunorubicin can be synthesized by pure chemical synthesis by using the intermediate compound. The daunorubicin is synthesized by taking 2,5-dihydroxybenzyl alcohol as a raw material. The route has low raw material cost, mild reaction condition, convenient post-treatment, high total yield, and good industrial application prospect.

The invention relates to a preparation method of a KRAS G12D intermediate. Specifically, the method for preparing the compound as shown in the formula (V-1) is simple in preparation process route, and the cost can be remarkably reduced.

Methods are provided for the synthesis of cannabinoids, including cannabidiol (CBD), cannabinol (CBN), cannabichromene (CBC), cannabidiolic acid (CBDA), cannabigerol (CBG), cannabigerolic acid (CBGA), cannabidivarin (CBDV), cannabidibutol (CBD-C4), dihydrocannabidiol (DCBD), tetrahydrocannabivarin (THCV), analogs thereof, and precursors to the foregoing. One method employs phloroglucinol or a phloroglucinol analog as a starting material. The syntheses are stereospecific, efficient, selective, and cost-effective, with little or no potential for generation of THC ((−)-trans-Δ9-tetrahydro-cannabinol) or any other psychoactive side product. Telescoped syntheses are also provided, as are new cannabinoids, pharmaceutical formulations, and methods of use.

Provided are: 1,1,1,5,5,5-hexafluoro-3-(2,2,2-trifluoroethoxy)-2-pentene which is a new compound; and a use application and a production method for the new compound.　The present invention provides 1,1,1,5,5,5-hexafluoro-3-(2,2,2-trifluoroethoxy)-2-pentene. This new compound can be produced by, for example, reacting 1,1,1,5,5,5-hexafluoro-3-chloro-2-pentene and 2,2,2-trifluoro ethanol in the presence of a base. Further, the new compound is useful as an additive in a nonaqueous electrolytic solution of a secondary battery.

The research aims to optimize the synthesis process of oxyfluorfen, improve the product yield and purity, and turn byproducts into wealth. According to an original process route, resorcinol is used as a starting raw material, and oxyfluorfen is synthesized through double etherification, nitration and ether exchange. After optimization, the total yield reaches 94.1%, and the purity reaches 98.4%. In order to improve the utilization rate of the raw materials, an acidic water phase obtained after quenching of an oxyfluorfen reaction solution is subjected to reduced pressure distillation, the byproduct 3-chloro-4-hydroxy-trifluorotoluene is recovered, and the yield can reach 93.7%. Further serving as a raw material of a new process, and synthesizing a target product through nucleophilic substitution. In the route, 2, 4-dichloronitrobenzene with moderate reaction activity and better selectivity is innovatively used for replacing 2, 4-difluoronitrobenzene, so that side reaction is effectively inhibited, and a target product with the content of 98.7% is obtained at the total yield of 94.8%. According to the new and old combination strategy, through integration of two process routes, high-valued conversion of by-products is realized, limitation of a traditional synthesis method is broken through, and atom economy is remarkably improved.

The invention discloses a simple synthesis method of 2, 2, 2-trifluoroethyl ether, and belongs to the field of organic synthesis. According to the synthesis method, the easily available 2, 2, 2-trifluoroethanol, trifluoromethanesulfonic anhydride / trifluoromethanesulfonyl chloride and the like are directly adopted to synthesize the 2, 2, 2-trifluoroethyl ether in one step under the action of organic alkali and under the conditions of normal temperature and normal pressure, dangerous metal / high temperature and high pressure / gas delivery is not involved, the preparation cost of the 2, 2, 2-trifluoroethyl ether is greatly reduced, and the synthesis method is suitable for an industrial production route.

The invention belongs to the technical field of power equipment fault diagnosis, and particularly relates to a preparation method of a fault diagnosis agent for transformer insulating oil. The preparation method comprises the following steps: mixing a phenolic compound, a halogenated hydrocarbon compound, alkali and a solvent, carrying out a stirring reaction, and carrying out optional cooling, optional filtering, optional filtrate concentration and optional purification to obtain the fault diagnosis agent. The preparation method of the fault diagnosis agent provided by the invention is simple in reaction steps, does not need complex equipment and is easy to industrialize; cheap and easily available raw materials are used, no catalyst is used, and the cost is low; the reaction conditions are mild, the safety is high, and the method is environment-friendly; and the product has high purity and good compatibility with insulating oil.

The application belongs to the field of medicine synthesis, and particularly relates to a chemical synthesis method of an epirubicin intermediate, daunorubicin. The daunorubicin is synthesized by taking 2,5-dihydroxybenzyl alcohol as raw material, the route has low raw material cost, mild reaction condition, convenient post-treatment, high total yield, and has a good industrial application prospect.

The invention discloses a preparation method of a tergorazan intermediate, which comprises the following steps: (1) 3, 5-difluorophenol and 3-chloro-1-propanol are dissolved in isopropanol, the molar ratio of the 3-chloro-1-propanol to the 3, 5-difluorophenol is (1-1.5): 1, alkali is added, and heating reflux reaction is performed; (2) 3-bromo-1-propanol is added into the reaction system in the step (1), the molar ratio of the 3-bromo-1-propanol to the 3, 5-difluorophenol is (0.1-0.15): 1, and heating reflux reaction is continued; and (3) after the reaction is finished, filtering and concentrating under reduced pressure to obtain the intermediate compound 3-(3, 5-difluorophenoxy)-1-propanol of the tergorazan. According to the method, dangerous reagents are not used, the industrial production cost can be reduced, the yield is high, and the product purity is high.

The invention discloses a triazole group-containing compound as well as application and a preparation method thereof. The invention specifically discloses a compound I. The compound I has one or more advantages as follows: the compound I is novel in structure, good in stabilizing effect on membrane protein with a complex structure, easy to synthesize, capable of being prepared on a large scale, excellent in character and easy in quality control.

The invention provides a method for catalytic continuous synthesis of aryl methyl ether, and belongs to the field of aryl methyl ether. The method for catalytically and continuously synthesizing the aryl methyl ether is carried out in a manner of combining continuous reaction and continuous rectification. According to the method for catalytically and continuously synthesizing the aryl methyl ether, the continuous production of the aryl methyl ether can be realized while dimethyl sulfate is not adopted and a large amount of high-toxicity wastewater and solid wastes are prevented from being generated in the production process, and the continuous production of the aryl methyl ether is mild in reaction condition, low in requirement on production equipment, small in production risk and high in production efficiency; the yield of the aryl methyl ether prepared through large-scale production is high, and large-scale industrial production is facilitated.

The invention discloses a phosphorus-modified magnesium-aluminum hydrotalcite acid catalyst and a preparation method and application thereof, and belongs to the technical field of catalyst preparation.The preparation method comprises the steps that a mixed metal salt solution of magnesium nitrate and aluminum nitrate or an aluminum nitrate solution is subjected to a first water bath reaction, then the pH of the solution is adjusted to 9.5, a second water bath reaction is conducted, and after the second water bath reaction, the phosphorus-modified magnesium-aluminum hydrotalcite acid catalyst is obtained; washing the obtained precipitate to be neutral, drying and roasting to obtain hydrotalcite; the preparation method comprises the following steps: adding hydrotalcite into water, stirring until the hydrotalcite is swelled to obtain hydrotalcite slurry, adjusting the pH value of the slurry to 5.5-6, heating, adding a phosphorus-containing compound, carrying out an exchange reaction, and drying to obtain the phosphorus-modified magnesium-aluminum hydrotalcite acid catalyst. The phosphorus-modified magnesium-aluminum hydrotalcite acid catalyst synthesized by the invention is used for synthesizing o-methoxyphenol by reaction of catechol and dimethyl carbonate, and has better conversion rate and excellent stability.

The invention belongs to the field of novel preparation methods of magnesium-aluminum hydrotalcite, and particularly relates to a preparation method of a magnesium-aluminum composite oxide-based catalyst and application of the magnesium-aluminum composite oxide-based catalyst in preparation of anisole. Magnesium nitrate hexahydrate and sodium metaaluminate are respectively dissolved in deionized water, stirred until being dissolved, mixed and aged; carrying out suction filtration, drying and grinding to obtain a catalyst precursor magnesium-aluminum hydrotalcite; the preparation method comprises the following steps: dipping magnesium-aluminum hydrotalcite into a metal salt solution, heating and stirring in a water bath, and carrying out dipping, drying and roasting cycles for several times to obtain a magnesium-aluminum composite oxide-based catalyst; the metal salt at least contains one of lanthanum, barium, manganese and zirconium metal salts. The active component elements of the catalyst are transition metal, alkaline earth metal and rare earth metal oxides and do not contain noble metal, so that the preparation cost is low; active components are loaded on the surface of the magnesium-aluminum composite oxide carrier in a one-step loading manner, and the process is simple and convenient.

The invention discloses a plant-based plasticizer as well as a continuous flow process production method and application thereof. When the plant-based plasticizer provided by the invention is used as a rubber composition plasticizer, the Mooney viscosity of a rubber composition can be remarkably reduced, the processability is improved, and the scorching time, the vulcanization efficiency and the strength of the rubber composition can be remarkably improved. Meanwhile, the modified plant-based plasticizer is prepared by adopting a continuous flow process, so that the production safety can be remarkably improved, the efficiency of epoxidation reaction and the consistency of products can be improved, and the method is suitable for large-scale production.

The present invention relates to a manufacturing method of a precursor based on cashew nut shell oil (CNSL) and, more specifically, to a manufacturing method of the precursor using hydrogenated cardanol in which an unsaturated aromatic ring has been modified.

The invention relates to the technical field of synthesis of hydroquinone dihydroxyethyl ether, in particular to a synthesis method of high-purity hydroquinone dihydroxyethyl ether. Comprising the following steps: enabling hydroquinone and ethylene carbonate to react in the presence of a compound catalyst in the absence of a solvent and under the protection of inert gas; after the reaction is finished, cooling a reaction mixture, and adding a reducing agent for reduction treatment to obtain a reaction crude product; sequentially carrying out reduced pressure rectification and melt crystallization treatment on the reaction crude product to obtain refined hydroquinone dihydroxyethyl ether; by adopting a compound catalyst system consisting of a basic catalyst and an organic catalyst, the reaction selectivity and efficiency are remarkably improved, and the generation of monosubstituted byproducts is effectively inhibited; and by combining the reduction treatment at the later stage of the reaction and the purification process of vacuum distillation and melt crystallization, impurity introduction and oxidation side reaction are avoided, so that the hydroquinone dihydroxyethyl ether with high purity and low product chroma is efficiently obtained.

The invention discloses a modified gamma-Al2O3 catalyst as well as a preparation method and application thereof, and belongs to the technical field of industrial catalyst preparation. The invention relates to a preparation method of a modified gamma-Al2O3 catalyst, which comprises the following steps: adding a triblock copolymer into an organic solvent, then adding nitric acid and a precursor, heating and stirring the obtained mixture to react, then heating and evaporating to dryness, and drying and roasting the obtained solid to obtain the modified gamma-Al2O3 catalyst, the metal source is selected from lanthanum nitrate, cerium nitrate or zirconium nitrate. The modified gamma-Al2O3 catalyst synthesized through the one-pot method is used for synthesizing anisole through the oxygen alkylation reaction of phenol and dimethyl carbonate, and has good conversion rate and excellent selectivity.

The invention discloses a preparation method of octabromo-ether, and belongs to the technical field of flame retardants, the preparation method comprises the following steps: synthesizing tetrabromobisphenol A, synthesizing tetrabromobisphenol A diallyl ether, and synthesizing tetrabromobisphenol A bis (2, 3-dibromopropyl) ether; the synthesis of tetrabromobisphenol A diallyl ether comprises the following steps: mixing tetrabromobisphenol A, methanol and a first part of deionized water, heating to 50-55 DEG C, stirring and refluxing until the tetrabromobisphenol A, methanol and the first part of deionized water are completely dissolved, adding sodium hydroxide, stirring and refluxing, adding a catalyst, stirring and refluxing, dropwise adding 3-chloropropene, then continuing stirring and refluxing, distilling out all methanol, and cooling to room temperature to obtain the tetrabromobisphenol A diallyl ether. Mixing with a second part of deionized water and dichloromethane, stirring at room temperature, standing, taking an organic layer, centrifuging, taking supernate, washing with deionized water, distilling out all dichloromethane, and drying; the prepared octabromo-ether is high in purity and yield and good in appearance performance, the condensation problem of the obtained octabromo-ether is avoided, and the yield is stable.

To provide: a polyhydric hydroxy resin which can form a cured product excellent in heat resistance, moisture resistance, low dielectricity, high thermal conductivity and the like, and is useful in applications such as lamination, molding, casting and bonding; and an epoxy resin thereof.SOLUTION: The polyhydric hydroxy resin is represented by the general formula (1) in the figure, where A represents a divalent aromatic group and n represents a number from 1 to 50. The epoxy resin is obtained by reacting the polyhydric hydroxy resin with epichlorohydrin.SELECTED DRAWING: None

The invention belongs to the technical field of papermaking chemical synthesis, particularly discloses anacardol methyl ether for synthesizing alkenyl succinic anhydride as well as a preparation method and application thereof, and aims to solve the technical problems that the existing alkenyl succinic anhydride synthesis depends on imported internal olefin, and the cost is high. The preparation method comprises the following steps: under the protection of nitrogen, adding cardanol and absolute methanol into a reaction kettle, adding a catalyst and an antioxidant, and reacting at 150-200 DEG C for 4-8 hours; and after the reaction is finished, removing generated water and excessive methanol through reduced pressure distillation to obtain the target product anacardol methyl ether. Renewable and cheap cardanol is used as a core raw material, the technical monopoly of alkenyl succinic anhydride synthesis is effectively broken through, and the production cost of alkenyl succinic anhydride is remarkably reduced. In addition, the preparation process is simple, reaction conditions are mild, the sizing performance of alkenyl succinic anhydride synthesized by using the cardanol methyl ether is equivalent to that of commercially available products, and the cardanol methyl ether has a good industrial popularization prospect.