The invention discloses a quick-response liquid crystal composition which comprises 1-80% of component A composed of dielectric positive compounds disclosed as general formula I and general formula II, 1-80% of component B disclosed as general formula III, 1-80% of component C disclosed as general formula IV, 0-30% of component D disclosed as general formula V, and component E disclosed as general formula VI. Besides, an optical rotation compound, which accounts for 0-1.0 wt% of the liquid crystal composition, is also added. The quick-response liquid crystal composition disclosed by the invention has the advantages of moderately high positive dielectric anisotropy, wide nematic phase range, very high charge retentivity, low power consumption, low rotary viscosity, quick response time and appropriate optical anisotropy, is suitable for active matrix and passive matrix electro-optic elements and liquid crystal displays, and can be used for manufacturing quick-response TFT-LCDs (thin film transistor-liquid crystal displays).